Extramedullary hematopoiesis: A report of two cases.

Abstract:

:Extramedullary hematopoiesis (EMH) is defined as hematopoiesis occurring in organs outside of the bone marrow. The present report describes two cases of thalassemic patients with paraspinal medullary hematopoiesis and analyzes the clinical manifestations, imaging, pathology, diagnosis and treatment of EMH. In addition, a supplementary review of previously published cases is provided along with a review of the related literature. Computed tomography (CT) of the first case revealed multiple paraspinal masses, and the largest was 6.2×8.0 cm in diameter. Likewise, CT of the second patient revealed multiple paraspinal masses in the bottom of the left thoracic cavity, and the largest was measured 10.1×10.5 cm. The two cases underwent surgical biopsy and the findings were compatible with a diagnosis of EMH. In conclusion, EMH is a compatible and rare disease, and should be distinguished from other neoplasms. EMH must considered when masses with characteristic radiologic appearance are detected in patients with thalassemia intermedia.

journal_name

Exp Ther Med

authors

Zhang HZ,Li Y,Liu X,Chen BR,Yao GH,Peng YN

doi

10.3892/etm.2016.3855

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

3859-3862

issue

6

eissn

1792-0981

issn

1792-1015

pii

ETM-0-0-3855

journal_volume

12

pub_type

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