Physical health conditions associated with full and subthreshold PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study.

Abstract:

BACKGROUND:While both full and subthreshold posttraumatic stress disorder (PTSD) may be linked to physical conditions, contemporary population-based data on these associations in military veterans are scarce. Further, little is known about how component aspects of PTSD, which is a heterogeneous disorder, may relate to physical conditions in this population. METHODS:Data were analyzed from a population-based sample of 3157 U.S. military veterans who participated in the 2011 National Health and Resilience in Veterans Study. Multiple logistic regression analyses evaluated associations between full and subthreshold PTSD, and physical conditions. RESULTS:A total 6.1% of the sample met screening criteria for full PTSD and 9.0% for subthreshold PTSD. Both full and subthreshold PTSD were associated with increased odds of sleep disorder (adjusted odds ratio [AOR] = 3.52 and 2.10, respectively) and respiratory conditions (AOR = 2.60 and 1.87, respectively). Full PTSD was additionally associated with increased odds of osteoporosis or osteopenia (AOR = 2.72) and migraine (AOR = 1.91), while subthreshold PTSD only was associated with increased odds of diabetes (AOR = 1.42). Analyses of PTSD symptom clusters revealed that all of these associations were primarily driven by dysphoric arousal symptoms, which are characterized by sleep difficulties, anger/irritability, and concentration problems. LIMITATIONS:The study used self-report measures for health conditions and DSM-IV diagnostic criteria for PTSD. CONCLUSION:Results of this study provide a characterization of physical conditions associated with full and subthreshold PTSD in U.S. military veterans. They highlight the potential importance of PTSD dysphoric arousal in risk models of certain physical conditions in this population.

journal_name

J Affect Disord

authors

El-Gabalawy R,Blaney C,Tsai J,Sumner JA,Pietrzak RH

doi

10.1016/j.jad.2017.11.058

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

849-853

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(17)31072-8

journal_volume

227

pub_type

杂志文章
  • Gender differences in the prevalence of depression: a survey in primary care.

    abstract::Epidemiological surveys demonstrate that unipolar depression is more common in females than in males. Gender-specific cultural and social factors may contribute to the female preponderance. This study explores this possibility in a cross-cultural sample of general-practice patients systematically recruited in the WHO ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(98)00131-1

    authors: Maier W,Gänsicke M,Gater R,Rezaki M,Tiemens B,Urzúa RF

    更新日期:1999-06-01 00:00:00

  • Developing an early warning system of suicide using Google Trends and media reporting.

    abstract:BACKGROUND:Conventional surveillance systems for suicides typically suffer from a substantial time lag of six months to two years. This study aims to develop an early warning system of possible suicide outbreaks in Hong Kong using Google Trends and suicide-related media reporting. METHODS:Data on 3,534 suicides from 2...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.05.030

    authors: Chai Y,Luo H,Zhang Q,Cheng Q,Lui CSM,Yip PSF

    更新日期:2019-08-01 00:00:00

  • Subthreshold anxiety better defined by symptom self-report than by diagnostic interview.

    abstract:BACKGROUND:There is no consensus on how to define subthreshold anxiety. Based on functional impairment, we aim to evaluate the use of a diagnostic instrument and an anxiety severity questionnaire to derive an empirical cut-off for defining clinically relevant, subthreshold anxiety. METHODS:Our sample consisted of 1788...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2010.09.006

    authors: Karsten J,Nolen WA,Penninx BW,Hartman CA

    更新日期:2011-03-01 00:00:00

  • Role of lamotrigine in the management of treatment-resistant bipolar II depression: a chart review.

    abstract:OBJECTIVES:We report the results of a retrospective, naturalistic study of lamotrigine in the management of treatment-resistant bipolar II depression. METHODS:Hospital charts of 31 patients treated at a mood disorders clinic, who had been on lamotrigine for at least six months after failing to show an adequate respons...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2008.01.029

    authors: Sharma V,Khan M,Corpse C

    更新日期:2008-11-01 00:00:00

  • Night shift work in resident physicians: does it affect mood states and cognitive levels?

    abstract:BACKGROUND:The effects of night shift work on health status have been widely studied. Night workers seem to smoke more, eat badly and show a low propensity to physical activity. Night work can be associated with an increase in cardiovascular and gastrointestinal disorders, alterations in immune response, diabetes, agin...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.03.139

    authors: Costa C,Mondello S,Micali E,Indelicato G,Licciardello AA,Vitale E,Briguglio G,Teodoro M,Fenga C

    更新日期:2020-07-01 00:00:00

  • Distribution of ancestral secondary cases in anxiety neurosis (panic disorder).

    abstract::The Slater computational model for use in distinguishing between polygenic inheritance and the effects of a single dominant gene with incomplete penetrance was applied to 15 kindreds of anxiety neurosis (panic disorder). The number of observed unilateral pairs (two ancestral cases from one side of the kindred) was sig...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:

    authors: Pauls DL,Crowe RR,Noyes R Jr

    更新日期:1979-12-01 00:00:00

  • Dietary magnesium intake and the incidence of depression: A 20-year follow-up study.

    abstract:BACKGROUND:Depression is a major global public health concern. The aetiology of depression is partly unclear; however, intake of nutrients, such as magnesium, have been suggested to affect depressive symptoms and modify depression risk. METHODS:This research is a part of the Kuopio Ischemic Heart Disease Risk Factor (...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.12.056

    authors: Yary T,Lehto SM,Tolmunen T,Tuomainen TP,Kauhanen J,Voutilainen S,Ruusunen A

    更新日期:2016-03-15 00:00:00

  • Daytime midpoint as a digital biomarker for chronotype in bipolar disorder.

    abstract:BACKGROUND:Bipolar disorder (BD) is associated with later sleep and daily activity (evening rather than morning chronotype). Objective chronotype identification (e.g., based on actigraphs/smartphones) has potential utility, but to date, chronotype has mostly been assessed by questionnaires. Given the ubiquity of accele...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.08.032

    authors: Kaufmann CN,Gershon A,Depp CA,Miller S,Zeitzer JM,Ketter TA

    更新日期:2018-12-01 00:00:00

  • Key concepts in screening for depression in people with diabetes.

    abstract:BACKGROUND:The prevalence of depression is increased in people with diabetes and there are both national and international recommendations for screening of depression in people with diabetes. The aim of this review is to assess the justification for screening for depression in people with diabetes. METHODS:The viabili...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/S0165-0327(12)70011-3

    authors: Holt RI,van der Feltz-Cornelis CM

    更新日期:2012-10-01 00:00:00

  • Validity of Gotland Male Depression Scale for male depression in a community study: the Sudurnesjamenn study.

    abstract:BACKGROUND:Several studies suggest a "male depressive syndrome", where not only the standard symptoms of major depressive disorder (MDD) but also symptoms of anxiety, anger, irritability and antisocial behaviour are prominent. METHOD:In a community study, 534 males were screened for possible depression by the Gotland ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.10.065

    authors: Sigurdsson B,Palsson SP,Aevarsson O,Olafsdottir M,Johannsson M

    更新日期:2015-03-01 00:00:00

  • Fluoxetine: no association with suicidality in obsessive-compulsive disorder.

    abstract::Since (a) obsessive-compulsive disorder (OCD) may involve serotonergic neural transmission abnormalities also though to be related to regulation of suicide and aggression, (b) comorbidity between OCD and depression is substantial, and (c) depression is a major risk factor for suicide, a comprehensive analysis of clini...

    journal_title:Journal of affective disorders

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/0165-0327(92)90054-a

    authors: Beasley CM Jr,Potvin JH,Masica DN,Wheadon DE,Dornseif BE,Genduso LA

    更新日期:1992-01-01 00:00:00

  • The relationship between temperament and sexual orientation.

    abstract:BACKGROUND:The relationship between temperament and sexual orientation has been poorly characterized. We have used the Affective and Emotional Composite Temperament (AFECT) model to evaluate this association in a large population sample. METHODS:Data from 16,571 subjects between 21 and 45 years old (mean age=29.1±6.3 ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.01.029

    authors: Guerim LD,de Carvalho HW,Lara DR

    更新日期:2015-04-01 00:00:00

  • Social class in unipolar and bipolar probands and relatives.

    abstract::130 patients fulfilling DSM-III-R criteria for bipolar disorder (n = 62), bipolar disorder not otherwise specified (n = 19) and major depression (n = 49) were included in a comparative study on the occupational levels of uni- and bipolar probands and relatives. The occupational levels did not significantly differ betw...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(94)00087-p

    authors: Verdoux H,Bourgeois M

    更新日期:1995-03-14 00:00:00

  • Anti-anxiety drugs reduce conflict-specific "theta"--a possible human anxiety-specific biomarker.

    abstract:BACKGROUND:Syndromes of fear/anxiety are currently ill-defined, with no accepted human biomarkers for anxiety-specific processes. A unique common neural action of different classes of anxiolytic drugs may provide such a biomarker. In rodents, a reduction in low frequency (4-12 Hz; "theta") brain rhythmicity is produced...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jad.2012.11.057

    authors: McNaughton N,Swart C,Neo P,Bates V,Glue P

    更新日期:2013-05-15 00:00:00

  • Hopelessness in adolescents.

    abstract:BACKGROUND:The hopelessness scales devised by Beck and by Kazdin have been used in hundreds of studies of both non-clinical and clinical samples. The present study identified non-clinical adolescent samples to see if the mean scores differed by age, sex, year of publication of the study, and nation. METHODS:Studies of...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.10.048

    authors: Lester D

    更新日期:2015-03-01 00:00:00

  • Impact of early onset bipolar disorder on family functioning: adolescents' perceptions of family dynamics, communication, and problems.

    abstract:OBJECTIVE:This research investigated the impact of adolescent onset bipolar illness on perceived family functioning in stabilized bipolar I (B) and unipolar (U) probands, and normal controls (C). METHOD:Sample N=119: 44 bipolar 1(17 M, 27 F), 30 unipolar (9 M, 21 F), and 45 controls (19 M, 26 F). Mean ages: 19.9, 18.5...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(00)00281-0

    authors: Robertson HA,Kutcher SP,Bird D,Grasswick L

    更新日期:2001-09-01 00:00:00

  • Fluvoxamine and lithium in long-term treatment of unipolar subjects with high recurrence rate.

    abstract::We prolonged from 24 to 36 months a follow-up study of unipolar subjects with a high probability of recurrence treated with fluvoxamine (n = 32) or lithium (n = 32). During the extra observation period, two patients developed mania and were excluded from the study. There were no further recurrences in either the lithi...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(95)00095-x

    authors: Franchini L,Zanardi R,Gasperini M,Perez J,Smeraldi E

    更新日期:1996-04-26 00:00:00

  • The association between cannabis use and mood disorders: A longitudinal study.

    abstract:BACKGROUND:The association between cannabis use and mood disorders is well documented, yet evidence regarding causality is conflicting. This study explored the association between cannabis use, major depressive disorder (MDD) and bipolar disorder (BPD) in a 3-year prospective study. METHODS:Data was drawn from waves 1...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.10.006

    authors: Feingold D,Weiser M,Rehm J,Lev-Ran S

    更新日期:2015-02-01 00:00:00

  • Darwinian depression.

    abstract:BACKGROUND:The standard evolutionary explanation for depression is that being in an emotionally depressed state is adaptive. METHOD:The article first undertakes a critical review of the extant literature. It then provides an alternative evolutionary explanation for event-based depression and elation. It argues that be...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/j.jad.2014.06.052

    authors: Wittman D

    更新日期:2014-10-01 00:00:00

  • Negative affectivity moderated by BDNF and stress response.

    abstract:BACKGROUND:Gene×environment (G×E) interactions are known to predict susceptibility to disorders such as depression and anxiety. Adverse experiences in childhood and number of stressful life events (SLEs) have been widely studied as environmental risk factors; however, SLE response has not yet been studied. Here we pres...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2011.09.043

    authors: Perea CS,Paternina AC,Gomez Y,Lattig MC

    更新日期:2012-02-01 00:00:00

  • Dissociative experiences differentiate bipolar-II from unipolar depressed patients: the mediating role of cyclothymia and the Type A behaviour speed and impatience subscale.

    abstract:BACKGROUND:Dissociative symptoms are often seen in patients with mood disorders, but there is little information on possible association with subgroups and temperamental features of these disorders. METHODS:The Dissociative Experience Scale was administered to 85 patients with a DSM-IV Major Depressive Disorder (MDD) ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2007.10.018

    authors: Oedegaard KJ,Neckelmann D,Benazzi F,Syrstad VE,Akiskal HS,Fasmer OB

    更新日期:2008-06-01 00:00:00

  • Serotonin transporter clustering in blood lymphocytes as a putative biomarker of therapeutic efficacy in major depressive disorder.

    abstract:BACKGROUND:Serotonin transporter (SERT) binding is decreased in lymphocytes of depression patients and this decrease is partially reversed by antidepressant medication. However, recent evidence has shown that clustering of SERT on cell membranes is very important for receptor functionality. Alteration in SERT clusterin...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2011.12.041

    authors: Rivera-Baltanas T,Olivares JM,Calado-Otero M,Kalynchuk LE,Martinez-Villamarin JR,Caruncho HJ

    更新日期:2012-03-01 00:00:00

  • The prevalence and clinical correlates of anger attacks during depressive episodes in bipolar disorder.

    abstract:BACKGROUND:Anger attacks, characterized by sudden episodes of intense anger with autonomic arousal, have been described in patients with major depressive disorder (MDD). This study compared the prevalence and clinical significance of anger attacks in unipolar versus bipolar depression. METHODS:Using the questionnaire ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/S0165-0327(02)00451-2

    authors: Perlis RH,Smoller JW,Fava M,Rosenbaum JF,Nierenberg AA,Sachs GS

    更新日期:2004-04-01 00:00:00

  • Is the type of remission after a major depressive episode an important risk factor to relapses in a 4-year follow up?

    abstract:BACKGROUND:Rates of relapse and predictive relapse factors were studied over more than 4 years in a sample of Spanish outpatients with DSM-III-R criteria for unipolar major depressive episode. METHODS:A final sample of 139 outpatient was followed monthly in a naturalistic study. The Structured Clinical Interview for D...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2003.11.008

    authors: Pintor L,Torres X,Navarro V,Matrai S,Gastó C

    更新日期:2004-10-15 00:00:00

  • Lifestyle behaviors predict adolescents bullying victimization in low and middle-income countries.

    abstract:BACKGROUND:In this study we aimed to provide a global perspective of the association between different lifestyle behaviors and bullying in school adolescents and to ascertain whether or not the Human Development Index moderated those associations. METHODS:Data from the Global school-based Student Health Survey were an...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.04.065

    authors: Alfonso-Rosa RM,García-Hermoso A,Sanders T,Parker P,Oriol-Granado X,Arnott H,Del Pozo Cruz B

    更新日期:2020-08-01 00:00:00

  • Eighteen months of drug treatment for depression: predicting relapse and recovery.

    abstract:BACKGROUND:The clinically relevant outcomes in treating depression are persistent recovery, relapse, and treatment resistance. METHOD:175 outpatients treated with antidepressants for 6 months were assessed for major depression. Those who had recovered were prospectively monitored for one year to study rates of relapse...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jad.2008.08.002

    authors: Mulder RT,Frampton CM,Luty SE,Joyce PR

    更新日期:2009-04-01 00:00:00

  • TrkB gene expression and DNA methylation state in Wernicke area does not associate with suicidal behavior.

    abstract:BACKGROUND:Alterations of DNA methylation and expression of suicide-related genes occurring in specific brain's areas have been associated to suicidal behavior. In the BDNF pathway, TrkB gene in frontal cortex and hippocampus, and BDNF gene in Wernicke area have been found hypermethylated and down-regulated in suicide ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2011.07.003

    authors: Keller S,Sarchiapone M,Zarrilli F,Tomaiuolo R,Carli V,Angrisano T,Videtic A,Amato F,Pero R,di Giannantonio M,Iosue M,Lembo F,Castaldo G,Chiariotti L

    更新日期:2011-12-01 00:00:00

  • The neural correlates of reward-related processing in major depressive disorder: a meta-analysis of functional magnetic resonance imaging studies.

    abstract:BACKGROUND:A growing number of functional magnetic resonance imaging (fMRI) studies have been conducted in major depressive disorder (MDD) to elucidate reward-related brain functions. The aim of this meta-analysis was to examine the common reward network in the MDD brain and to further distinguish the brain activation ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jad.2013.06.039

    authors: Zhang WN,Chang SH,Guo LY,Zhang KL,Wang J

    更新日期:2013-11-01 00:00:00

  • Functional disability, depression, and suicidal ideation in older prisoners.

    abstract:BACKGROUND:The population of older prisoners (age ≥50), a group with high suicide rates, is growing. We sought to explore the associations among functional disability, depression, and suicidal ideation (SI) among older prisoners, focusing on the mediating role of depression. METHODS:Study participants were 220 sentenc...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.01.156

    authors: Barry LC,Coman E,Wakefield D,Trestman RL,Conwell Y,Steffens DC

    更新日期:2020-04-01 00:00:00

  • An adoption study comparing the prevalence of psychiatric illness in women who have adoptive and natural children compared with women who have adoptive children only.

    abstract::The current study compares the current and lifetime prevalence of affective disorder in women who have adopted and have natural children (n = 110) with women who only have adopted children (n = 176). There was no difference in lifetime prevalence of psychiatric disorder between the two groups and a nonsignificant tren...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(94)00105-i

    authors: Dean C,Dean NR,White A,Liu WZ

    更新日期:1995-04-16 00:00:00