What are the prevalence, characteristics and significance of fetal lateral neck cysts detected in an early anatomical scan?

Abstract:

PURPOSE:This study evaluated the association of fetal lateral neck cysts (FLNC) with adverse pregnancy outcomes, in relation to specific sonographic characteristics and co-existing findings. METHODS:Pregnancies in which FLNC were detected by a single examiner in early anatomical scans (14-16 weeks) were included. Data regarding the pregnancy and its outcome were retrieved from telephone-based questionnaires, patient charts and from the examiner's reports. RESULTS:654 cases of FLNC were detected among 9446 early anatomical scans (6.9%). Complete data regarding 219 pregnancies were available. FLNC were significantly more prevalent in males (65.2%). The prevalence of heart malformations was 3.2% [all were non-isolated cases or with abnormal nuchal translucency (NT) and/or nuchal fold (NF)]. Amniocentesis performed in 165 pregnancies was abnormal in 1.2%. Among 206 children born from this cohort, adverse medical outcomes were reported in 5.3%. The likelihood of adverse pregnancy outcomes was significantly higher in non-isolated cases and in cases with abnormal NT or NF. Sonographic characteristics such as cyst size and bilateral findings were not linked to adverse pregnancy outcomes. CONCLUSION:Isolated FLNC are benign findings which do not require additional work up. FLNC with additional sonographic abnormalities are associated with a significantly increased risk for adverse pregnancy outcomes.

journal_name

Arch Gynecol Obstet

authors

Sukenik Halevy R,Mashiach Friedler J,Hershko-Klement A,Biron-Shental T,Markovitch O,Tepper R

doi

10.1007/s00404-018-4747-z

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

51-58

issue

1

eissn

0932-0067

issn

1432-0711

pii

10.1007/s00404-018-4747-z

journal_volume

298

pub_type

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