Abstract：
:Cohesin-Dockerin interactions are at the core of cellulosomal assembly and organization. They are highly specific and form stable complexes, allowing cellulosomes to adopt distinct conformations. Each cellulosomal system seems to have a particular organizational strategy that can vary in complexity according to the nature of its Cohesin-Dockerin interactions. Hence, several efforts have been undertaken to reveal the mechanisms that govern the specificity, affinity and flexibility of these protein-protein interactions. Here we review the most recent studies that have focused on the structural aspects of Cohesin-Dockerin recognition. They reveal an ever-increasing number of subtle intricacies suggesting that cellulosome assembly is more complex than was initially thought.
journal_name
Curr Opin Struct Bioljournal_title
Current opinion in structural biologyauthors
Bule P,Pires VM,Fontes CM,Alves VDdoi
10.1016/j.sbi.2018.03.012subject
Has Abstractpub_date
2018-04-01 00:00:00pages
154-161eissn
0959-440Xissn
1879-033Xpii
S0959-440X(17)30212-9journal_volume
49pub_type
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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doi：10.1016/j.sbi.2009.06.003
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
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journal_title：Current opinion in structural biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in structural biology
pub_type： 杂志文章,评审
doi：10.1016/s0959-440x(96)80088-1
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abstract：:2-Oxoacid:ferredoxin oxidoreductases (OFORs) are essential enzymes in microbial one-carbon metabolism. They use thiamine pyrophosphate to reversibly cleave carbon-carbon bonds, generating low potential (∼-500mV) electrons. Crystallographic analysis of a recently discovered OFOR, an oxalate oxidoreductase (OOR), has pr...
journal_title：Current opinion in structural biology
pub_type： 杂志文章,评审
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abstract：:The radical intermediates generated during the catalytic cycles of adenosylcobalamin-dependent enzymes occur in pairs. The positions of radicals residing on the cofactor, substrate or protein, relative to the position of the low-spin Co(2+) from the cob(II)alamin intermediate, can be extracted from electron paramagnet...
journal_title：Current opinion in structural biology
pub_type： 杂志文章,评审
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journal_title：Current opinion in structural biology
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