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The Influence of Preoperative Interventions on Postoperative Surgical Wound Healing in Patients Without Risk Factors: A Systematic Review.

Abstract：

Background:Poor wound healing and scar formation remain critical problems in daily surgical practice. Generally, most attention is paid to intra- and postoperative interventions to improve wound healing after surgery, while preoperative interventions remain unsatisfactorily explored. Objectives:In this systematic review, the available literature on the beneficial effects of preoperative interventions on wound healing and scar formation have been summarized and compared. Methods:A comprehensive and systematic search has been conducted in MEDLINE, Pubmed, Embase, Web of Science, and Cochrane, supplemented by reference and citation tracking. All preoperative interventions and all clinically relevant outcome parameters have been considered for inclusion, due to the expected limited availability of literature. Results:A total of 13 studies were included, which were all randomized trials. No cohort studies or retrospective studies have been identified. All studies described different preoperative interventions and outcome parameters and could hence not be pooled and compared. Eight studies showed significantly better wound healing after a preoperative intervention. The individual studies have been summarized in this review. Conclusions:This systemic review shows that preoperative interventions can be beneficial in improving wound healing and scar formation. In selected cases, wound healing was found to benefit from a higher preoperative body temperature, topical vitamin E application, and low patient stress levels. Level of Evidence 2:

journal_name

Aesthet Surg J

journal_title

Aesthetic surgery journal

authors

Geers NC,Zegel M,Huybregts JGJ,Niessen FB

doi

10.1093/asj/sjy074

subject

Has Abstract

pub_date

2018-10-15 00:00:00

pages

1237-1249

issue

11

eissn

1090-820X

issn

1527-330X

pii

4955177

journal_volume

38

pub_type

杂志文章

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