当前位置： SCI文献检索 > TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE期刊下所有文献 > Quantifying the physical and socio-economic burden of filarial lymphoedema in Chikwawa District, Malawi.

Quantifying the physical and socio-economic burden of filarial lymphoedema in Chikwawa District, Malawi.

Abstract：

BACKGROUND:Lymphatic filariasis (LF) is a disfiguring parasitic disease and one of the leading causes of disability in the world. This study aimed to assess the severity of lymphoedema, the physical restrictions and socio-economic impact on affected individuals living in an endemic community in Malawi. METHODS:In a single health centre catchment area, a follow-up survey was conducted to assess 69 lymphoedema cases, and the impact of their condition in eight different areas of their lives. Differences were examined by sex, age and severity of disease. The overall level of disability was quantified and the impact of acute dermatolymphangioadenitis (ADLA) attacks was examined. RESULTS:Lymphoedema cases were most affected by pain/discomfort and anxiety/depression, which also had an economic impact. Male and older (>60 years) individuals reported more problems. Higher disability levels based on a quantified score were significantly associated with decreased walking distance and working hours. ADLA significantly increased pain/discomfort and reduced cognition, and also affected the individuals' self-care, social participation and ability to work. CONCLUSIONS:Filarial lymphoedema causes significant hardship, particularly in relation to ADLAs, and the scale of the problem needs to be better defined with new specific tools so that the best support and care can be provided to those in greatest need.

journal_name

Trans R Soc Trop Med Hyg

journal_title

Transactions of the Royal Society of Tropical Medicine and Hygiene

authors

Martindale S,Mkwanda SZ,Smith E,Molyneux D,Stanton MC,Kelly-Hope LA

doi

10.1093/trstmh/tru154

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

759-67

issue

12

eissn

0035-9203

issn

1878-3503

pii

tru154

journal_volume

108

pub_type

杂志文章

相关文献

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE文献大全
  • Onchocerciasis in Ecuador, IV. Comparative studies of the disease relating to the Chachi and black populations in the province of Esmeraldas.

    abstract：:The frequency, intensity and clinical features of onchocerciasis in the two ethnic groups (Blacks and Chachilla--an indigenous tribe) in the endemic foci of the disease in Esmeraldas province (Ecuador) were evaluated. The incidence of infection and intensity of the disease seen in both groups were directly related to ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(84)90183-4

    authors： Molea J,Guderian RH,Proaño R,Carrillo R,Swanson WL

    更新日期：1984-01-01 00:00:00

  • Clinical and laboratory features of South American rattlesnake (Crotalus durissus terrificus) envenomation in children.

    abstract：:The venom of the South American rattlesnake Crotalus durissus terrificus was first reported to have mainly haemolytic and neurotoxic physiopathological activities. Later studies demonstrated the systemic myotoxic action of the venom, characterized by the release of myoglobin from damaged skeletal muscle into serum and...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(88)90044-2

    authors： Cupo P,Azevedo-Marques MM,Hering SE

    更新日期：1988-01-01 00:00:00

  • Trichiasis and geoclimatic factors in Mali.

    abstract：:Several trachoma surveys conducted in sub-Saharan countries showed different geographical distributions of active trachoma and trichiasis. Trichiasis is more common in southern regions. We analysed the role of geoclimatic factors in determining the distributions of active trachoma and trichiasis in Mali. In each regio...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/j.trstmh.2007.05.015

    authors： Schémann JF,Laffly D,Sacko D,Zephak G,Malvy D

    更新日期：2007-10-01 00:00:00

  • Disability, mental health, stigma and discrimination and neglected tropical diseases.

    abstract：:The neglected tropical disease (NTD) agenda should include a focus on disability when 'planning for the next decade of progress'. Millions of people are currently living with the disabling consequences of NTDs and mental health conditions are frequent among people living with NTDs. Stigma around NTDs is also common. H...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1093/trstmh/traa160

    authors： Kuper H

    更新日期：2020-12-12 00:00:00

  • Exercise electrocardiogram tests in manual workers with and without antibodies to Trypanosoma cruzi: a population-based study.

    abstract：:Blood pressure, heart rate and electrocardiographic responses to exercise were compared in a group of 125 subjects with antibodies to Trypanosoma cruzi and in 153 seronegative subjects, randomly selected from persons with no evidence of heart disease in a resting electrocardiogram during a cross-sectional survey among...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(90)90081-o

    authors： Zicker F,Zicker EM,Oliveira JJ,Netto JC,Oliveira RM,Smith PG

    更新日期：1990-11-01 00:00:00

  • Antibody detection tests for Onchocerca volvulus: comparison of the sensitivity of a cocktail of recombinant antigens used in the indirect enzyme-linked immunosorbent assay with a rapid-format antibody card test.

    abstract：:There is a need for a specific, sensitive, and practical diagnostic test to monitor onchocerciasis elimination campaigns. In April 2001, an enzyme-linked immunosorbent assay (ELISA) using 3 recombinant antigens and a rapid-format antibody card test (immunochromatographic test; ICT) using an individual antigen were com...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/s0035-9203(03)80018-4

    authors： Rodríguez-Pérez MA,Domínguez-Vázquez A,Méndez-Galván J,Sifuentes-Rincón AM,Larralde-Corona P,Barrera-Saldaña HA,Bradley JE

    更新日期：2003-09-01 00:00:00

  • Non-bacterial etiologies of diarrheal diseases in Afghanistan.

    abstract：BACKGROUND:Microbial diarrheal diseases are one of the leading causes of child morbidity and mortality in developing countries. This study aimed to identify the main causes of non-bacterial diarrhea in Afghanistan. METHODS:A total of 699 stools were collected from children aged under 5 years who presented with diarrhe...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1093/trstmh/tru096

    authors： Elyan D,Wasfy M,El Mohammady H,Hassan K,Monestersky J,Noormal B,Oyofo B

    更新日期：2014-08-01 00:00:00

  • Brucellosis: imported and laboratory-acquired cases, and an overview of treatment trials.

    abstract：:Following the successful eradication of Brucella abortus infection in cattle, human brucellosis in England and Wales has become an uncommon imported disease. Culture of the organism presents a major laboratory hazard, and difficulties in identification may occur using a biochemical test-strip method. An overview of re...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章,评审

    doi：10.1016/0035-9203(93)90460-8

    authors： Luzzi GA,Brindle R,Sockett PN,Solera J,Klenerman P,Warrell DA

    更新日期：1993-03-01 00:00:00

  • Consequences of poor maternal micronutrition before and during early pregnancy.

    abstract：:In developing countries, micronutrient deficiencies are common and associated with poor pregnancy outcomes, which may in turn have longer-term effects on human health. The peri-conceptional period represents a particularly sensitive window of feto-placental development, during which suboptimal maternal micronutrition ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章,评审

    doi：10.1016/j.trstmh.2007.09.018

    authors： Owens S,Fall CH

    更新日期：2008-02-01 00:00:00

  • Schistosoma mansoni in pregnancy and associations with anaemia in northwest Tanzania.

    abstract：:Schistosomiasis among pregnant women has been inadequately investigated. In order to determine the importance of Schistosoma mansoni in this subgroup, we conducted a cross-sectional survey of 972 women in Tanzania and investigated the prevalence of Schistosoma mansoni, hookworm and malaria and their associations with ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/j.trstmh.2005.06.024

    authors： Ajanga A,Lwambo NJ,Blair L,Nyandindi U,Fenwick A,Brooker S

    更新日期：2006-01-01 00:00:00

  • Incidence of localized cutaneous leishmaniasis (chiclero's ulcer) in Mexico.

    abstract：:Cutaneous leishmaniasis in Mexico was first described in 1912. Since then, its existence has been repeatedly confirmed in the forest regions of the peninsula of Yucatan. In order to obtain reliable knowledge about the magnitude of this problem, we questioned and skin-tested a sample of 449 persons randomly selected fr...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(90)90262-d

    authors： Andrade-Narváez FJ,Simmonds-Díaz E,Rico-Aguilar S,Andrade-Narvéez M,Palomo-Cetina A,Canto-Lara SB,García-Miss MR,Madera-Sevilla M,Albertos-Alpuche N

    更新日期：1990-03-01 00:00:00

  • Blood pressures of South African Black adolescents aged 16 to 17 years.

    abstract：:In South Africa, in urban but not rural areas, hypertension is far more common in Black than in White adults. To throw light on this adverse situation, blood pressures are being determined in various segments of Black populations, in the present instance on series of school pupils aged 16 to 17 years, in rural and urb...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(80)90147-9

    authors： Walker AR,Walker BF,Daya L,Ncongwane J

    更新日期：1980-01-01 00:00:00

  • Emergence of Crimean-Congo hemorrhagic fever.

    abstract：:Crimean-Congo hemorrhagic fever (CCHF) is a life-threatening tick-borne infection in Africa and Eurasia. Although knowledge of epidemiology is increasing, the global extent and risk of infection is not well described. A niche-modeling framework has been used to map the global distribution of risk for CCHF based on ana...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 评论,杂志文章

    doi：10.1093/trstmh/trv083

    authors： Leblebicioglu H,Ozaras R,Erciyas-Yavuz K

    更新日期：2015-11-01 00:00:00

  • Enterotoxigenic Escherichia coli as a cause of paediatric diarrhoea in Ujung Pandang, Indonesia.

    abstract：:The importance of enterotoxigenic Escherichia coli (ETEC) as a cause of diarrhoea in eastern Indonesia was investigated in 74 children during the dry season in Ujung Pandang. Six of the children less than five years old with diarrhoea were infected with ETEC. One child was infected with tetracycline-resistant bacteria...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(83)90015-9

    authors： Maidin MA

    更新日期：1983-01-01 00:00:00

  • Helminth transmission in simple pit latrines.

    abstract：:Simple pit latrines often represent the cheapest form of sanitation for poor communities. However, simple latrines lack a concrete slab and are therefore classified as an unimproved form of sanitation. This study collected soil samples in simple pit latrines and analysed them for the presence of helminth eggs; 71% of ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/j.trstmh.2012.08.002

    authors： Baker SM,Ensink JH

    更新日期：2012-11-01 00:00:00

  • Spatial and temporal variation in biting rates and parasite transmission potentials of onchocerciasis vectors in Ecuador.

    abstract：:The influence of spatial and temporal factors on onchocerciasis transmission by Simulium exiguum s.l. and S. quadrivittatum in Ecuador was investigated to help develop sampling protocols for entomological surveillance of ivermectin programmes. Flies were collected in alternate months (November 1995-November 1996) at f...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/j.trstmh.2004.03.012

    authors： Vieira JC,Brackenboro L,Porter CH,Basáñez MG,Collins RC

    更新日期：2005-03-01 00:00:00

  • Chancroid in Nigeria.

    abstract：:The present paper records the incidence of chancroid in northern Nigeria. Out of 776 new patients registered at the Special Treatment Clinic (STC) of the Ahmadu Bello University Teaching Hospital (ABUTH) Zaria during February to August 1982, 34 cases (4.38%) were diagnosed as chancroid. Direct smear examination for Ha...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(83)90198-0

    authors： Joshi RM,Lawande RV

    更新日期：1983-01-01 00:00:00

  • Hepatitis B assessment without hepatitis B virus DNA quantification: a prospective cohort study in Uganda.

    abstract：Background:Chronic hepatitis B infection affects 240 million people, with the highest prevalence in Africa and Asia, and results in 700 000 deaths annually. Access to diagnostics, particularly for hepatitis B virus viral load quantification (HBV DNA), is a major barrier to treatment. We aimed to test World Health Organ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1093/trstmh/try117

    authors： Laing N,Tufton H,Ochola E,P'Kingston OG,Maini MK,Easom N

    更新日期：2019-01-01 00:00:00

  • Sensitization against the parasite antigen Sj26 is not sufficient for consistent expression of resistance to Schistosoma japonicum in mice.

    abstract：:Mice immunized with purified antigen preparations produced in Escherichia coli and containing the glutathione S-transferase (GST) isoenzyme of Schistosoma japonicum (Sj26) can be partially resistant to infection with this parasite. Maximum resistance was approximately 50% and no protection was obtained in BALB/c mice,...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(88)90027-2

    authors： Mitchell GF,Garcia EG,Davern KM,Tiu WU,Smith DB

    更新日期：1988-01-01 00:00:00

  • Dynamics of schistosoma haematobium infection in a Gambian community. II. The effect on transmission of the control of Bulinus senegalensis by the use of niclosamide.

    abstract：:Niclosamide was used to interrupt transmission of Schistosoma haematobium by Bulinus senegalensis in seasonal rainwater pools for a period of three years. Snail populations were progressively reduced to approximately 1% of the numbers in untreated pools. There was little or no evidence of acquisition of new infection ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(84)90282-7

    authors： Goll PH,Wilkins HA,Marshall TF

    更新日期：1984-01-01 00:00:00

  • Comparison between spontaneous sedimentation method and Paratest® for the diagnosis of intestinal parasitic infections.

    abstract：:Correct diagnosis of parasitic infections is essential for the treatment of individuals avoiding indiscriminate use of anthelmintics which increases drug resistance. In a comparative study between the spontaneous sedimentation technique and Paratest(®), 140 stool samples were analyzed for the detection of parasites. T...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/j.trstmh.2011.06.002

    authors： Brandelli CL,Cargnin ST,Willers DM,Oliveira KR,Tasca T

    更新日期：2011-10-01 00:00:00

  • Wildlife rabies in Europe and the British situation.

    abstract：:The red fox is considered to be the main reservoir of the present European rabies epizootic which began in Poland in 1939-40. Its usual rate of spread is 20 to 60 km a year. Mortality among rabies-infected fox populations is estimated variously to be 20 to 60%. The infection spreads more rapidly among foxes in the aut...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章,评审

    doi：10.1016/0035-9203(76)90036-5

    authors： Lloyd HG

    更新日期：1976-01-01 00:00:00

  • Projected costs associated with school-based screening to inform deployment of Dengvaxia: Vietnam as a case study.

    abstract：Background:After new analysis, Sanofi Pasteur now recommends their dengue vaccine (Dengvaxia) should only be given to individuals previously infected with dengue and the World Health Organization's recommendations regarding its use are currently being revised. As a result, the potential costs of performing large-scale ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1093/trstmh/try057

    authors： Turner HC,Wills BA,Rahman M,Quoc Cuong H,Thwaites GE,Boni MF,Clapham HE

    更新日期：2018-08-01 00:00:00

  • Development and validation of a 'tablet pole' for the administration of praziquantel in sub-Saharan Africa.

    abstract：:A pole estimating, for each individual, the number of praziquantel tablets needed for treatment according to height was tested in 20 data sets (n = 25,688). In more than 98% of the cases the indicated dose was within the range that has proven efficacious and safe (30 and 60 mg/kg). ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/s0035-9203(01)90034-3

    authors： Montresor A,Engels D,Chitsulo L,Bundy DA,Brooker S,Savioli L

    更新日期：2001-09-01 00:00:00

  • Kala-azar in displaced people from southern Sudan: epidemiological, clinical and therapeutic findings.

    abstract：:Six hundred and ninety-three patients with kala-azar were seen in Khartoum, Sudan, from January 1989 to February 1990. They were almost exclusively from the Nuer tribe, originating from the western Upper Nile province in southern Sudan, an area not known previously to be endemic for kala-azar. Because of the civil war...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(91)90293-8

    authors： Zijlstra EE,Ali MS,el-Hassan AM,el-Toum IA,Satti M,Ghalib HW,Sondorp E,Winkler A

    更新日期：1991-05-01 00:00:00

  • Yellow fever risk assessment in the Central African Republic.

    abstract：BACKGROUND:Starting in 2008, the Central African Republic (CAR) experienced an unprecedented number of reported yellow fever (YF) cases. A risk assessment of YF virus (YFV) activity was conducted to estimate potential disease risk and vaccine needs. METHODS:A multistage cluster sampling design was used to sample human...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1093/trstmh/tru086

    authors： Staples JE,Diallo M,Janusz KB,Manengu C,Lewis RF,Perea W,Yactayo S,Sall AA,RCA Risk Assessment Team.

    更新日期：2014-10-01 00:00:00

  • Distribution of Angiostrongylus cantonensis in Papua New Guinea.

    abstract：:Examination of 97 rats trapped in Port Moresby and Lae on the mainland of Papua New Guinea and in Rabaul, East New Britain Province, showed that 12.4% were infected by Angiostrongylus cantonensis. Larval An. cantonensis were found in Achatina fulica snails collected at these towns, from the Ramu Valley near Madang on ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(84)90017-8

    authors： Scrimgeour EM

    更新日期：1984-01-01 00:00:00

  • The ecology and epidemiology of Ross River and Murray Valley encephalitis viruses in Western Australia: examples of One Health in Action.

    abstract：:Arboviruses are maintained and transmitted through an alternating biological cycle in arthropods and vertebrates, with largely incidental disease in humans and animals. As such, they provide excellent examples of One Health, as their health impact is inextricably linked to their vertebrate hosts, their arthropod vecto...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1093/trstmh/trx045

    authors： Mackenzie JS,Lindsay MDA,Smith DW,Imrie A

    更新日期：2017-06-01 00:00:00

  • Influence of Toxoplasma on manifestations of Moloney virus infections.

    abstract：:Considerable evidence documents the importance of co-factors, including the immune response, in expression of oncogenicity of tumour viruses. To determine whether a common protozoal infection that can depress lymphocyte function alters manifestations of oncogenic virus infection, a mouse model of Toxoplasma infection ...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/0035-9203(85)90116-6

    authors： McLeod R,Estes RG,Cohen H

    更新日期：1985-01-01 00:00:00

  • Detection of Crimean-Congo haemorrhagic fever virus antibodies in humans and imported livestock in Saudi Arabia.

    abstract：:A survey of Crimean-Congo haemorrhagic fever virus antibody, using the reversed passive haemagglutination inhibition test, was carried out in Saudi Arabia on sera from imported livestock at Jeddah seaport, as well as humans who had contact with imported animals on farms and in quarantine stations. Antibodies were dete...

    journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type： 杂志文章

    doi：10.1016/s0035-9203(97)90014-6

    authors： Hassanein KM,el-Azazy OM,Yousef HM

    更新日期：1997-09-01 00:00:00