当前位置： SCI文献检索 > JOURNAL OF AFFECTIVE DISORDERS期刊下所有文献 > Features of dissociation differentially predict antidepressant response to ketamine in treatment-resistant depression.

Features of dissociation differentially predict antidepressant response to ketamine in treatment-resistant depression.

Abstract：

BACKGROUND:Ketamine induces rapid and robust antidepressant effects, and many patients also describe dissociation, which is associated with antidepressant response. This follow-up study investigated whether antidepressant efficacy is uniquely related to dissociative symptom clusters. METHODS:Treatment-resistant patients with major depressive disorder (MDD) or bipolar disorder (BD) (n = 126) drawn from three studies received a single subanesthetic (0.5 mg/kg) ketamine infusion. Dissociative effects were measured using the Clinician-Administered Dissociative States Scale (CADSS). Antidepressant response was measured using the 17-item Hamilton Depression Rating Scale (HAM-D). A confirmatory factor analysis established the validity of CADSS subscales (derealization, depersonalization, amnesia), and a general linear model with repeated measures was fitted to test whether subscale scores were associated with antidepressant response. RESULTS:Factor validity was supported, with a root mean square error of approximation of .06, a comparative fit index of .97, and a Tucker-Lewis index of .96. Across all studies and timepoints, the depersonalization subscale was positively related to HAM-D percent change. A significant effect of derealization on HAM-D percent change was observed at one timepoint (Day 7) in one study. The amnesia subscale was unrelated to HAM-D percent change. LIMITATIONS:Possible inadequate blinding; combined MDD/BD datasets might have underrepresented ketamine's antidepressant efficacy; the possibility of Type I errors in secondary analyses. CONCLUSIONS:From a psychometric perspective, researchers may elect to administer only the CADSS depersonalization subscale, given that it was most closely related to antidepressant response. From a neurobiological perspective, mechanistic similarities may exist between ketamine-induced depersonalization and antidepressant response, although off-target effects cannot be excluded.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Niciu MJ,Shovestul BJ,Jaso BA,Farmer C,Luckenbaugh DA,Brutsche NE,Park LT,Ballard ED,Zarate CA Jr

doi

10.1016/j.jad.2018.02.049

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

310-315

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(17)32478-3

journal_volume

232

pub_type

临床试验,杂志文章

相关文献

JOURNAL OF AFFECTIVE DISORDERS文献大全
  • Effects of vitamin D supplementation on depression and some involved neurotransmitters.

    abstract：BACKGROUND:Low vitamin D levels are associated with a dysregulated hypothalamic-pituitary-adrenal (HPA) axis and depression but a causal relationship has not been established. This study aimed to evaluate the effects of vitamin D supplementation on depression severity, serum 25(OH)D, and some neurotransmitters in patie...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.03.029

    authors： Kaviani M,Nikooyeh B,Zand H,Yaghmaei P,Neyestani TR

    更新日期：2020-05-15 00:00:00

  • Mental health service use among those with depression: an exploration using Andersen's Behavioral Model of Health Service Use.

    abstract：BACKGROUND:Despite positive effects on prognosis, less than half of the people diagnosed with depression access mental health services. Knowledge of what promotes such service use is limited. There is dispute about whether the receipt of mental illness related information encourages or discourages service use among tho...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2016.08.074

    authors： Graham A,Hasking P,Brooker J,Clarke D,Meadows G

    更新日期：2017-01-15 00:00:00

  • Diverse pathophysiological processes converge on network disruption in mania.

    abstract：BACKGROUND:Neuroimaging of psychiatric disease is challenged by the difficulty of establishing the causal role of neuroimaging abnormalities. Lesions that cause mania present a unique opportunity to understand how brain network disruption may cause mania in both lesions and in bipolar disorder. METHODS:A literature se...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.10.087

    authors： Lee I,Nielsen K,Nawaz U,Hall MH,Öngür D,Keshavan M,Brady R Jr

    更新日期：2019-02-01 00:00:00

  • Reduced integrity of the uncinate fasciculus and cingulum in depression: A stem-by-stem analysis.

    abstract：INTRODUCTION:The subgenual cingulate gyrus (Brodmann's Area 25: BA25) is hypermetabolic in depression and has been targeted successfully with deep brain stimulation. Two of the white matter tracts that play a role in treatment response are the uncinate fasciculus (UF) and the cingulum bundle. The UF has three prefronta...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.04.055

    authors： Bhatia KD,Henderson LA,Hsu E,Yim M

    更新日期：2018-08-01 00:00:00

  • Depression in Mongolian women over the first 2 months after childbirth: prevalence and risk factors.

    abstract：BACKGROUND:Social, political and economic changes in Mongolia have followed post-Soviet style government policies and contributed to both increased liberalisation and reduced security in employment and family finances. This is the first study to attempt to assess the prevalence of depression in a population of Mongolia...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2008.11.010

    authors： Pollock JI,Manaseki-Holland S,Patel V

    更新日期：2009-07-01 00:00:00

  • What factors predict discrepancies between self and observer ratings of depression?

    abstract：:This study used a matched clinician and self-rating scale, the Inventory for Depressive Symptomatology (IDS; Rush et al., 1986), in the assessment of 48 patients meeting DSM-III-R criteria for non-psychotic major depressive disorder. Patients generally rated their symptoms as more severe than the clinician, but differ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(94)90101-5

    authors： Domken M,Scott J,Kelly P

    更新日期：1994-08-01 00:00:00

  • Relationship of anhedonia and anxiety to social rank, defeat and entrapment.

    abstract：:There is good evidence to suggest that depression is highly correlated with perceptions of low rank and subordinate status (i.e. feeling inferior, low-self esteem, feeling that others look down on the self, and submissive behaviour). However, it is possible for people to feel inferior and anxious, and behave submissiv...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(01)00392-5

    authors： Gilbert P,Allan S,Brough S,Melley S,Miles JN

    更新日期：2002-09-01 00:00:00

  • Emotional complexity across the life story: Elevated negative emodiversity and diminished positive emodiversity in sufferers of recurrent depression.

    abstract：BACKGROUND:Greater diversity in the experience of negative and positive emotions - emodiversity - is associated with better mental health outcomes in the general population (Quoidbach et al. 2014). However, conceptual accounts of depression suggest this might differ in clinical depression. In this study, the diversity ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.04.060

    authors： Werner-Seidler A,Hitchcock C,Hammond E,Hill E,Golden AM,Breakwell L,Ramana R,Moore R,Dalgleish T

    更新日期：2020-08-01 00:00:00

  • Treatment-emergent mania in pediatric bipolar disorder: a retrospective case review.

    abstract：BACKGROUND:Pediatric bipolar disorder (BPD) can be misdiagnosed as a depressive, attention, conduct, or anxiety disorder and treatment with antidepressants and stimulants is common. Risk of adverse outcomes related to such treatment remains poorly defined. METHODS:We analyzed clinical records of 82 children (mean age ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2003.12.011

    authors： Faedda GL,Baldessarini RJ,Glovinsky IP,Austin NB

    更新日期：2004-10-01 00:00:00

  • Prevalence of paternal depression in pregnancy and the postpartum: An updated meta-analysis.

    abstract：BACKGROUND:Research in paternal prenatal and postpartum depression has nearly doubled since prevalence rates were last meta-estimated in October 2009. An updated meta-analysis allows additional questions to be answered about moderators that influence risk. METHODS:Studies reporting paternal depression between the firs...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jad.2016.07.044

    authors： Cameron EE,Sedov ID,Tomfohr-Madsen LM

    更新日期：2016-12-01 00:00:00

  • Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorder.

    abstract：OBJECTIVE:Anxiety disorders (AD) and substance use disorders (SUD) commonly co-occur with bipolar disorder. This study was undertaken to assess AD-SUD-bipolar subtype interactions. METHODS:Extensive clinical interview and MINI were used to ascertain DSM-IV diagnoses of rapid cycling bipolar I (RCBPDI) or II (RCBPDII) ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2007.12.229

    authors： Gao K,Tolliver BK,Kemp DE,Verduin ML,Ganocy SJ,Bilali S,Brady KT,Shim SS,Findling RL,Calabrese JR

    更新日期：2008-09-01 00:00:00

  • Where would young people seek help for mental disorders and what stops them? Findings from an Australian national survey.

    abstract：BACKGROUND:In order to improve help seeking by young people for mental illness, a better understanding is required of their help-seeking intentions and barriers to their help seeking from various different sources and for different disorders. METHODS:Young people's help-seeking intentions and perceived barriers to hel...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2012.11.014

    authors： Yap MB,Reavley N,Jorm AF

    更新日期：2013-05-01 00:00:00

  • Momentary assessment of PTSD symptoms and sexual risk behavior in male OEF/OIF/OND Veterans.

    abstract：BACKGROUND:Post-traumatic stress disorder (PTSD) in Veterans is associated with increased sexual risk behaviors, but the nature of this association is not well understood. Typical PTSD measurement deriving a summary estimate of symptom severity over a period of time precludes inferences about symptom variability, and w...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2015.10.039

    authors： Black AC,Cooney NL,Justice AC,Fiellin LE,Pietrzak RH,Lazar CM,Rosen MI

    更新日期：2016-01-15 00:00:00

  • Emerging issues and questions on peripartum depression prevention, diagnosis and treatment: a consensus report from the cost action riseup-PPD.

    abstract：BACKGROUND:Peripartum depression [PPD] is a public health problem which has been widely studied. Nonetheless, study findings and clinical guidelines for PPD treatment differ among countries and the condition is still underdiagnosed and undertreated, suggesting the importance of a global understanding of PPD. The Riseup...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2020.05.112

    authors： Fonseca A,Ganho-Ávila A,Lambregtse-van den Berg M,Lupattelli A,Rodriguez-Muñoz MF,Ferreira P,Radoš SN,Bina R

    更新日期：2020-09-01 00:00:00

  • Motor activity and autonomic cardiac functioning in major depressive disorder.

    abstract：BACKGROUND:The daily pattern of motor activity and the autonomic cardiovascular regulation were studied in major depression to quantify changes in psychomotor function and autonomic cardiac functioning. Additionally, relationships between motor activity parameters, cardiovascular measures and specific clinical features...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(02)00066-6

    authors： Volkers AC,Tulen JH,van den Broek WW,Bruijn JA,Passchier J,Pepplinkhuizen L

    更新日期：2003-09-01 00:00:00

  • Attempted suicide short intervention program influences coping among patients with a history of attempted suicide.

    abstract：BACKGROUND:The development of individual coping strategies for suicidal crises is essential for suicide prevention. However, the influence of a brief intervention and the effect on coping strategies is largely unknown. This study aimed to investigate the influence of the Attempted Suicide Short Intervention Program on ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.11.059

    authors： Gysin-Maillart A,Soravia L,Schwab S

    更新日期：2020-03-01 00:00:00

  • Examining differential effects of psychological treatment of depressive disorder: an application of trajectory analyses.

    abstract：BACKGROUND:Although different psychological treatments of depression seem equally effective, studies in this area have not taken sufficient account of the heterogeneity among patients. Modern techniques for longitudinal data analysis can be helpful in examining differential effects of psychological interventions on spe...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jad.2005.09.001

    authors： Cuijpers P,van Lier PA,van Straten A,Donker M

    更新日期：2005-12-01 00:00:00

  • The effects of ethnic, social and cultural factors on axis I comorbidity of bipolar disorder: results from the clinical setting in Korea.

    abstract：OBJECTIVE:Ethnic, social and cultural factors contribute to axis I comorbid conditions in bipolar disorder (BPD). Korea has strict laws against illicit drugs and a relatively permissive prevailing attitude toward alcohol. The present study aimed to explore the lifetime axis I comorbidity rate in patients with BPD in Ko...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.05.027

    authors： Baek JH,Cha B,Moon E,Ha TH,Chang JS,Kim JH,Choi JE,Kang BJ,Hong KS,Ha K

    更新日期：2014-09-01 00:00:00

  • Clinical symptoms and platelet monoamine oxidase in subgroups and different states of affective disorders.

    abstract：:Platelet monoamine oxidase activity (MAO) and clinical symptoms were examined in 116 individuals, 32 acute depressed patients and 84 healthy controls. The enzyme activity was lower in depressed women than controls. MAO activity correlated positively with rated clinical state in depressed women but not in depressed men...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(95)00043-m

    authors： Wahlund B,Sääf J,Wetterberg L

    更新日期：1995-10-09 00:00:00

  • Onset of Depression Inventory (ODI)--assessment of the speed of onset of depressive episodes.

    abstract：BACKGROUND:The development of a full blown depressive episode may be very rapid, taking less than one hour, or be very slow, taking up to months. In a previous study with outpatients it was found that the majority (58%) of depressive episodes within bipolar affective disorders (BD) develop within one week whereas this ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2012.05.002

    authors： Strauss M,Sander C,Mergl R,Merz C,Schönknecht P,Hegerl U

    更新日期：2012-12-15 00:00:00

  • Self-stigma, empowerment and perceived discrimination among people with bipolar disorder or depression in 13 European countries: the GAMIAN-Europe study.

    abstract：BACKGROUND:There is little information on the degree to which self-stigma is experienced by individuals with a diagnosis of bipolar disorder or depression across Europe. This study describes the levels of self-stigma, stigma resistance, empowerment and perceived discrimination reported in these groups. METHODS:Data we...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2010.09.001

    authors： Brohan E,Gauci D,Sartorius N,Thornicroft G,GAMIAN-Europe Study Group.

    更新日期：2011-03-01 00:00:00

  • Sensitivity to reward and punishment and the prefrontal cortex in major depression.

    abstract：BACKGROUND:Patients with major depressive disorder (MDD) show neuropsychological impairments, including deficient executive functions and altered sensitivity to reward and punishment. METHODS:Executive functions (Wisconsin Card Sorting Test, WCST) and contingency learning based on the cumulative effect of reward and p...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2005.12.005

    authors： Must A,Szabó Z,Bódi N,Szász A,Janka Z,Kéri S

    更新日期：2006-02-01 00:00:00

  • Do essential fatty acids have a role in the treatment of depression?

    abstract：BACKGROUND:Complementary and alternative medicine (CAM) therapies are used more than conventional therapies by people with self-defined anxiety and depression. Preliminary evidence supports a hypothesis that low plasma concentration of essential fatty acids is associated with depression. Reported here is the result of ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/j.jad.2006.02.023

    authors： Williams AL,Katz D,Ali A,Girard C,Goodman J,Bell I

    更新日期：2006-07-01 00:00:00

  • Single-nucleotide polymorphism in the human TIA1 gene interacts with stressful life events to predict the development of pathological anxiety symptoms in a Swedish population.

    abstract：BACKGROUND:The TIA1 gene encodes a prion-related RNA-binding protein that regulates stress-dependent synaptic plasticity and fear memory in mice. It is unknown whether genetic variation in human TIA1 is associated with differences in stress- and fear-related behavior in people. METHODS:A longitudinal, population-based...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.09.018

    authors： Rayman JB,Melas PA,Schalling M,Forsell Y,Kandel ER,Lavebratt C

    更新日期：2020-01-01 00:00:00

  • Daytime midpoint as a digital biomarker for chronotype in bipolar disorder.

    abstract：BACKGROUND:Bipolar disorder (BD) is associated with later sleep and daily activity (evening rather than morning chronotype). Objective chronotype identification (e.g., based on actigraphs/smartphones) has potential utility, but to date, chronotype has mostly been assessed by questionnaires. Given the ubiquity of accele...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.08.032

    authors： Kaufmann CN,Gershon A,Depp CA,Miller S,Zeitzer JM,Ketter TA

    更新日期：2018-12-01 00:00:00

  • Understanding the effects of emotional reactivity on depression and suicidal thoughts and behaviors: Moderating effects of childhood adversity and resilience.

    abstract：BACKGROUND:Early adulthood is a period of increased risk for depression and suicide. Emotional reactivity (a tendency to react to stress with increases in negative affect and maladaptive interpretations of events) is an important risk factor for these outcomes that has been under-studied. We hypothesized that elevated ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.11.033

    authors： Shapero BG,Farabaugh A,Terechina O,DeCross S,Cheung JC,Fava M,Holt DJ

    更新日期：2019-02-15 00:00:00

  • Suicidal ideation and affect lability in single and multiple suicidal attempters with Major Depressive Disorder: An exploratory network analysis.

    abstract：INTRODUCTION:A better understanding of the specific contribution of risk factors to suicidal behavior could arise from analyzing suicidal ideation (SI) in clinical samples, and comparing single versus multiple suicide attempters through contemporary methods allowing complex and dynamical analyses of multiple and simult...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.04.004

    authors： Núñez D,Ulloa JL,Guillaume S,Olié E,Alacreu-Crespo A,Courtet P

    更新日期：2020-07-01 00:00:00

  • Antidepressive effect of left dorsolateral prefrontal cortex neurofeedback in patients with major depressive disorder: A preliminary report.

    abstract：:Background Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) have recently attracted attention as a novel, individualized treatment method for major depressive disorder (MDD). In this study, the antidepressant effect of neurofeedback training for left dorsolateral prefrontal cortex (DLPFC) acti...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.03.080

    authors： Takamura M,Okamoto Y,Shibasaki C,Yoshino A,Okada G,Ichikawa N,Yamawaki S

    更新日期：2020-06-15 00:00:00

  • Effects of transcranial direct current stimulation for treating depression: A modeling study.

    abstract：BACKGROUND:Transcranial direct current stimulation (tDCS) above the left dorsolateral prefrontal cortex (lDLPFC) has been widely used to improve symptoms of major depressive disorder (MDD). However, the effects of different stimulation protocols in the entire frontal lobe have not been investigated in a large sample in...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.02.077

    authors： Csifcsák G,Boayue NM,Puonti O,Thielscher A,Mittner M

    更新日期：2018-07-01 00:00:00

  • Treatment and prevention of depression after surgery for hip fracture in older people: cost-effectiveness analysis.

    abstract：OBJECTIVE:For older people who have had hip fracture surgery, to evaluate the cost-effectiveness of a nurse-led intervention in treating depression compared to treatment as usual (TAU), and to evaluate the cost-effectiveness of a psychological treatment for the prevention of depression. DESIGN:Two linked cost-effectiv...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jad.2010.07.026

    authors： Romeo R,Knapp M,Banerjee S,Morris J,Baldwin R,Tarrier N,Pendleton N,Horan M,Burns A

    更新日期：2011-02-01 00:00:00