Abstract:
BACKGROUND:Depression is a frequent comorbidity of COPD and leads to worse clinical COPD-outcomes. PHQ-9 and PHQ-2 are two widely used brief instruments to assess depression. However, psychometric properties in COPD patients are unknown. This study examines factorial validity, measurement invariance and composite reliability (CR) of PHQ-9/PHQ-2, respectively, and concordance between both tools. METHODS:This is a secondary analysis of N = 561 COPD patients who filled out the PHQ-9 at the begin (T0), the end (T1) and 3/6/9/12 (T2/T3/T4/T5) months after pulmonary inpatient rehabilitation. Structural equation modeling was used to examine factorial validity and measurement invariance between gender, GOLD disease severity groups and over time. Concordance was assessed using Cohen's Kappa, Yules Y, positive and negative agreement. RESULTS:A one-factor model (with one freed residual covariance) showed best model fit. At least partial scalar invariance could be established. Concordance between both instruments was substantial. 31.7% (26.2%) COPD patients showed clinically relevant depression according to PHQ-9 (PHQ-2) at T0. At T0-T2, PHQ-9 classified more patients as depressed than did PHQ-2. According to both measures, depression rates declined after rehabilitation. Reliability was high for both PHQ-9 (CR = 0.94) and PHQ-2 (CR = 0.89). LIMITATIONS:No gold-standard (clinical interview) to assess depression was used. Therefore, diagnostic accuracy for PHQ-9/PHQ-2 remains unclear. CONCLUSIONS:PHQ-9 and PHQ-2 fulfill important psychometric criteria (factorial validity, invariance, reliability) for measuring depression in COPD. The results support their use in clinical practice to assess severity of depression. Diagnostic accuracy to identify major/minor depression of both instruments should be examined in future studies.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Schuler M,Strohmayer M,Mühlig S,Schwaighofer B,Wittmann M,Faller H,Schultz Kdoi
10.1016/j.jad.2018.02.037subject
Has Abstractpub_date
2018-05-01 00:00:00pages
268-275eissn
0165-0327issn
1573-2517pii
S0165-0327(17)32429-1journal_volume
232pub_type
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journal_title:Journal of affective disorders
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更新日期:2004-04-01 00:00:00
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journal_title:Journal of affective disorders
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pub_type: 杂志文章,meta分析,评审
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更新日期:2016-04-01 00:00:00
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更新日期:2021-02-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.03.022
更新日期:2013-09-05 00:00:00
abstract::Endogenously depressed in-patients were treated for four weeks with either lithium + L-tryptophan (N = 22) or amitriptyline (N = 21) in an open study. Before and weekly during treatment the patients were evaluated by means of Hamilton rating scale, and blood samples were collected for determination of serum concentrat...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(82)90022-2
更新日期:1982-03-01 00:00:00
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doi:10.1016/0165-0327(96)00030-4
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.jad.2011.11.044
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2021-02-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.050
更新日期:2014-01-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jad.2013.09.032
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Depressive and anxiety disorders affect work functioning and cause high labour costs. AIMS:To examine and compare psychopathological characteristics of depressive and anxiety disorders in their effect on work functioning. METHOD:In 1876 working participants of the Netherlands Study of Depression and Anxiet...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2010.01.072
更新日期:2010-09-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.03.044
更新日期:2014-07-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.03.034
更新日期:2015-07-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.01.029
更新日期:2007-11-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.09.014
更新日期:2013-04-25 00:00:00