Abstract:
OBJECTIVE:To describe the use of prescription drugs and their association with patient characteristics in patients with multiple functional somatic syndromes (FSS) focusing on drugs generally recommended and not recommended in FSS treatment. METHOD:Using data from a national prescription registry, we describe the drug use during a two-year period for 239 trial participants. Using regression models, we analyse the associations of patient characteristics with the patterns of use of antidepressants, anticonvulsants, opioids and sedatives. RESULTS:The use of prescription drugs was highly heterogeneous. Antidepressants were used at least temporarily by 34% (88/239), anticonvulsants by 7% (16/239), opioids by 26% (61/239) and sedatives by 20% (47/239) of the patients. Severe impairment due to multiple FSS was associated with use of opioids or sedatives (OR 6.49 (95% CI 2.68-15.68; p < 0.001)) but also with use of antidepressants or anticonvulsants (OR 3.42 (95% CI 1.35-8.65; p = 0.009)). Poor self-reported physical health, additional physical comorbidities and low socioeconomic status were associated with use of opioids or sedatives only. CONCLUSION:Antidepressants and anticonvulsants were modestly used. Opioids and sedatives were especially used by the severely affected patients. Balancing treatment expectations and enhancing patients' understanding of FSS may direct treatments towards more generally recommended drugs.
journal_name
Gen Hosp Psychiatryjournal_title
General hospital psychiatryauthors
Agger JL,Fink PK,Gormsen LK,Jensen JS,Schröder Adoi
10.1016/j.genhosppsych.2018.02.001subject
Has Abstractpub_date
2018-01-01 00:00:00pages
96-105eissn
0163-8343issn
1873-7714pii
S0163-8343(17)30464-4journal_volume
51pub_type
杂志文章abstract::Diligence in the interpretation of results is essential as information gained from the psychiatric patient's history might often be restricted. Nonobservance of established guidelines may lead to a wrong diagnosis, induce a false therapy and result in life-threatening situations. Communication errors between hospitals...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2010.03.002
更新日期:2010-09-01 00:00:00
abstract::A 63-year-old married man with idiopathic terminal cardiomyopathy was admitted to the medical service for treatment of advanced heart failure. A psychiatric consultation was requested to assist the medical treatment team in dealing with the patient's abusive behavior. The case is presented and discussed within the con...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(92)90099-v
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVE:The objectives of this study were to examine associations between depressive symptoms and body mass over 1 year during early adolescence and to assess how the associations might differ depending upon whether self-reported or directly measured height and weight were used. METHOD:Participants were 446 sixth-gr...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2008.06.008
更新日期:2008-09-01 00:00:00
abstract::The authors review the forces that encouraged the entry of psychiatry into the general hospital in the 1930s. Those forces, which included concern about increasing health care costs, pressure to reform medical and psychiatric education, and the growth of dynamic psychiatry and psychosomatic medicine, are described. Th...
journal_title:General hospital psychiatry
pub_type: 传,历史文章,杂志文章
doi:10.1016/0163-8343(87)90054-5
更新日期:1987-11-01 00:00:00
abstract::In response to the spiraling anger and frustration voiced by the emergency room (ER) medical staff and the observed negative interactions between the alcohol-dependent patient and the ER staff, the author completed a 6-month retrospective review of all patients evaluated by the ER service with a complaint of alcohol a...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(85)90026-x
更新日期:1985-04-01 00:00:00
abstract::Many general hospitals are confronting issues of financial strain precipitated to a large extent by Medicare payment reductions. The viability of psychiatry programs within general hospitals more than ever depends upon some demonstration of their financial as well as clinical contribution. The aim of this study is to ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(91)90035-u
更新日期:1991-09-01 00:00:00
abstract::This study describes and evaluates the adequacy of sociodemographic and clinical descriptors as potential predictors of unplanned discharge from and completion of psychiatric day treatment programs. A 2-year retrospective chart review was completed on all patients (N = 327) attending three university-affiliated day tr...
journal_title:General hospital psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/s0163-8343(97)00052-2
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:Demonstrate the feasibility of implementing a collaborative care program for poorly-controlled type 2 diabetes and complex behavioral health disorders in an urban academically-affiliated safety net primary care clinic. METHODS:This retrospective cohort study evaluates multidisciplinary team care approach to ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2016.10.005
更新日期:2017-01-01 00:00:00
abstract::A liaison rounds is presented, one attended by all members of a consultation-liaison (C-L) team along with the medical director of a burn unit. This structure is designated as a "reverse liaison rounds," as it is the opposite of the conventional liaison meeting, which consists of one C-L consultant and the total nonps...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(88)90087-4
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:The distinction between acute and chronic suicidality is important, because interventions designed to address acute suicidality can worsen chronic suicidality, resulting in an escalating cycle of suicide threats, suicide attempts, and futile hospitalizations. Though most chronically suicidal borderline person...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.genhosppsych.2020.08.014
更新日期:2020-01-01 00:00:00
abstract::In this preliminary study, the experimental presence of a consulting psychiatrist at medical rounds was instituted in a busy city hospital emergency room. The psychiatrist was instructed only to respond to questions on psychiatric topics. Students were asked to record data from the discussions which occurred both with...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(84)90063-x
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:Over the last decade, charcoal burning has become a common method of suicide in Taiwan; however, the underlying psychiatric diagnoses and gender differences have yet to be examined. METHODS:We conducted a retrospective chart review on inpatients after suicide attempt by charcoal burning during 2000-2010. The...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2012.03.015
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:Patients with acute-on-chronic liver failure (ACLF) experience long-term chronic liver diseases plus an acute liver function decompensation. This study aimed to determine whether psychological symptoms in patients with hepatitis B virus (HBV)-related ACLF differ from those with other chronic liver diseases a...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2011.11.012
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:This study examined the feasibility and efficacy of a psychosocial intervention to address high-risk substance use in patients scheduled for elective surgery. METHOD:A group-format intervention, based on motivational interviewing principles, was provided prior to elective surgery to 107 participants with at-...
journal_title:General hospital psychiatry
pub_type: 临床试验,杂志文章
doi:10.1016/j.genhosppsych.2014.08.002
更新日期:2014-11-01 00:00:00
abstract:INTRODUCTION:Chemical restraint is controversial. Appropriate use is ill-defined and chemical restraint may be overutilized. During the period of an unrelated observational study for patients with acute psychomotor agitation in a psychiatric emergency service, we noticed a significant reduction in the number of involun...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2006.06.001
更新日期:2006-09-01 00:00:00
abstract::This report describes the background, rationale, and research plan for a comparative treatment trial of the effectiveness of paroxetine, problem-solving therapy (PST-PC), and placebo in the treatment of minor depression and dysthymia in primary care patients. Patients were recruited from a variety of primary care prac...
journal_title:General hospital psychiatry
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.1016/s0163-8343(99)00023-7
更新日期:1999-07-01 00:00:00
abstract::The relationships specified in DSM-III between somatization disorder and depression, and somatization disorder and hypochondriasis require further validation and easier methods of detection for use by primary care physicians. The authors investigated hypochondriacal and depressive symptoms in 13 family practice outpat...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(85)90045-3
更新日期:1985-10-01 00:00:00
abstract::Efforts to improve the care of depression in primary care patients have largely ignored the potential of obstetrics/gynecology (OB/GYN) practices. We describe feasibility studies of a depression screening and care management intervention in three diverse OB/GYN practices. Patients were screened using the Patient Healt...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(03)00006-9
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVE:Thyroid dysfunction is common during pregnancy and the postpartum period and is known to cause psychiatric disturbances. A woman with Graves' disease and psychosis in the postpartum period is described. METHODS:A 22-year-old woman with Graves' disease developed fluctuating orientation, catatonia, delusions o...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.07.003
更新日期:2014-11-01 00:00:00
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journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(00)00118-3
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To report a case of Alzheimer's disease (AD) following mild traumatic brain injury (TBI). METHOD:Case report. RESULTS:We report the time course of AD following mild TBI with evidence of AD pathology. A patient complained of minor memory disturbance 6 months after TBI and was diagnosed with mild cognitive im...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.09.016
更新日期:2015-01-01 00:00:00
abstract::There has been increasing recognition and documentation of the impact of psychiatric problems on the outcome and cost of medical care. Because consultation-liaison psychiatrists have the expertise to address the psychiatric aspects of medical illness, this group should be in a strong position to facilitate integration...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/0163-8343(95)00053-t
更新日期:1995-07-01 00:00:00
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journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(79)90020-3
更新日期:1979-09-01 00:00:00
abstract:OBJECTIVE:To explore the relationship between treatment setting characteristics and diagnostic attributions of depression among community-dwelling African Americans. METHODS:Data come from the National Survey of American Life, a nationally representative sample of African Americans and Caribbean Blacks. Major Depressi...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2010.12.002
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Eating disorder (ED) symptoms have gone mostly unexamined among veterans. The current study assessed rates of bulimia nervosa (BN) and binge eating disorder (BED) symptoms and diagnoses and their associations with common comorbidities among male and female veterans. METHOD:Participants were US military veter...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.03.013
更新日期:2014-07-01 00:00:00
abstract::Little is known about which factors may adversely affect response to psychotherapy in diabetic patients with major depression. We studied the relationship of various demographic, diabetes, and depression characteristics to change in depression in 42 patients with type 2 diabetes who completed a randomized clinical tri...
journal_title:General hospital psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0163-8343(98)00039-5
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVE:Persons with thoughts of self-harm may need evaluation for suicide risk. We examine the prevalence of thoughts of self-harm and whether persons with thoughts of self-harm are identified when two-stage depression screening is used. METHODS:Data are from the 2005-2010 National Health and Nutrition Examination ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2013.09.007
更新日期:2014-01-01 00:00:00
abstract::Clinical observation had suggested that mild depression occurs after admission for acute medical treatment and then decreases during further hospitalization for rehabilitation treatment. The Geriatric Depression Scale (GDS) was given on admission and discharge to 14 stroke and 17 amputee rehabilitation patients. Each ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(92)90039-d
更新日期:1992-03-01 00:00:00
abstract::A common problem facing the psychiatric consultant and the medical practitioner is evaluating depression in patients with concurrent medical illnesses. Depression is difficult to recognize in the medically ill, often presenting with "masked" symptoms and organized into unique syndromes. A primary concern of the clinic...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/0163-8343(92)90024-5
更新日期:1992-01-01 00:00:00
abstract::Several predictors of the course of depression and generalized anxiety have been identified. Whether these predictors provide a solid basis for primary care physicians (PCPs) to give an accurate prognosis remains unclear. A parallel study showed modest agreement between PCP prognosis and observed course (kappa< or = 0...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(02)00183-4
更新日期:2002-05-01 00:00:00