Abstract:
:Several predictors of the course of depression and generalized anxiety have been identified. Whether these predictors provide a solid basis for primary care physicians (PCPs) to give an accurate prognosis remains unclear. A parallel study showed modest agreement between PCP prognosis and observed course (kappa< or = 0.21). It is the aim of the present study to establish the extent to which the one-year course of depression and generalized anxiety in primary care is in fact predictable. Predictability is operationalized as the combined predictive power of major prognostic factors identified in the literature. We identified 269 cases of ICD-10 depression and 134 of generalized anxiety among consecutive PCP attenders. For these patients a statistical model was built that provided optimal predictions of the one-year course of the disorder, based on the prognostic factors discerned. The predictions were compared with the actual course observed. Reasonable agreement (kappa = 0.37 for depression, kappa = 0.35 for anxiety) and good association (gamma = 0.66 for depression, gamma=0.67 for anxiety) were found between predicted and observed course. Nevertheless, the combined predictive power of the prognostic factors remains limited. A realistic evaluation of the accuracy of the PCP prognosis should take this limited predictability into account.
journal_name
Gen Hosp Psychiatryjournal_title
General hospital psychiatryauthors
van den Brink RH,Ormel J,Tiemens BG,Smit A,Jenner JA,van der Meer K,van Os TWdoi
10.1016/s0163-8343(02)00183-4subject
Has Abstractpub_date
2002-05-01 00:00:00pages
156-63issue
3eissn
0163-8343issn
1873-7714pii
S0163834302001834journal_volume
24pub_type
杂志文章abstract::Post-stroke depression is a potentially persistent complication of stroke. Electroconvulsive therapy (ECT) is an effective treatment for depression, but with limited data regarding safety in stroke patients. We report the case of a 30-year-old woman with a history of stroke and antiphospholipid syndrome, who became de...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2011.08.006
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:This study presents the psychometric properties of a brief measure to assess beliefs about psychotropic medications and psychotherapy among patients with anxiety disorders. METHOD:Data were collected on a large sample of primary care patients with a range of anxiety disorders, as part of the Collaborative Ca...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2005.05.005
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To describe a patient with behavioral variant frontotemporal dementia (bvFTD) presenting with impulse control disorders (ICDs) which responded to fluvoxamine and topiramate. CASE REPORT:A 64-year-old woman was affected by several ICDs. At disease onset, she suffered from impulsive smoking and overeating whic...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.06.005
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:We compare treatment for depression among individuals with multiple chronic physical conditions to those with single chronic physical condition, after controlling for demographic, socioeconomic, access to care and the number of outpatient visits. METHODS:Using a cross-sectional study design, we analyzed dat...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2011.02.009
更新日期:2011-05-01 00:00:00
abstract:INTRODUCTION:Recent surveys have assessed a remarkable increase in the prevalence of infectious syphilis. If left untreated, 30% of patients may develop tertiary syphilis, which can manifest as neurosyphilis. CASE REPORT:The authors present a case of an acute psychosis during and after pregnancy in a 37-year-old woman...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/j.genhosppsych.2008.09.010
更新日期:2009-07-01 00:00:00
abstract::This study examines the recognition and treatment of emotional distress in physically healthy primary care patients who perceive themselves to be in fair or poor physical health. Patients (N = 892) from three private primary care practices completed a mental health screening form prior to their medical visit which inc...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(95)00023-k
更新日期:1995-05-01 00:00:00
abstract:OBJECTIVE:This study examined the feasibility and efficacy of a psychosocial intervention to address high-risk substance use in patients scheduled for elective surgery. METHOD:A group-format intervention, based on motivational interviewing principles, was provided prior to elective surgery to 107 participants with at-...
journal_title:General hospital psychiatry
pub_type: 临床试验,杂志文章
doi:10.1016/j.genhosppsych.2014.08.002
更新日期:2014-11-01 00:00:00
abstract::Advancing medical technology presents problems to medical professionals previously unforeseen. Psychiatric consultants are frequently called upon to assist staff, patients, and families in addressing these issues. The nursing staff of an infant intensive care unit was surveyed as to their perceptions of their work and...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(89)90037-6
更新日期:1989-05-01 00:00:00
abstract::Suicidal behavior is disproportionately frequent among inner-city Hispanic adolescent girls. In an attempt to generate a multifactorial set of hypotheses to explain this behavior, 33 such subjects consecutively admitted for suicidal behavior and 15 demographically identical nonsuicidal subjects were assessed by means ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(91)90009-l
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:We examined whether primary care patients were more likely to perceive a current health problem as 'physical illness only' as opposed to entailing psychological difficulties if they had a comorbid somatoform disorder compared to patients who had (a) both comorbid somatoform disorder and anxiety/depression or...
journal_title:General hospital psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.genhosppsych.2015.01.002
更新日期:2015-03-01 00:00:00
abstract::Prior literature suggested that psychiatric liaison on medical wards would produce a more positive attitude towards psychiatry, more psychosocial chart documentation, and a higher consultation request rate. Over 3 years, liaison was conducted on two medical wards, and its effect was contrasted with two control (consul...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(89)90050-9
更新日期:1989-03-01 00:00:00
abstract::In this preliminary study, the experimental presence of a consulting psychiatrist at medical rounds was instituted in a busy city hospital emergency room. The psychiatrist was instructed only to respond to questions on psychiatric topics. Students were asked to record data from the discussions which occurred both with...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(84)90063-x
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:This prospective study aimed to estimate the prevalence and course of depression during chemotherapy in women with Stage I-III breast cancer, identify potential risk factors for depression and determine which treatments for depression were being used and which were most preferred. METHOD:Thirty-two women wer...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2013.03.017
更新日期:2013-07-01 00:00:00
abstract::Although dialysis discontinuation is the second leading "cause" of death among individuals who are maintained with chronic dialysis, little attention is accorded in the literature to patient ambivalence with this crucial decision. Three cases are presented of clinical situations involving termination of dialysis and a...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/s0163-8343(96)00091-6
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:Factors determining community tenure (CT) between subsequent referrals to a psychiatric emergency room (PER) are only partly understood. We investigated the differential effect of patient and health system characteristics on the CT of patients with a previous referral to a PER. METHOD:Data were collected for...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2005.04.003
更新日期:2005-07-01 00:00:00
abstract::The aim of this study was to assess the prevalence of alcohol abuse in a general hospital inpatient population. The study population consisted of 1138 consecutive admissions to three surgical and two medical wards of the University Hospital Rotterdam during a 6-month period. According to the Munich Alcoholism Test (MA...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(94)90056-6
更新日期:1994-03-01 00:00:00
abstract::Interviews with patients and staff of the New York Hospital Burn Unit in which they discuss their reactions to a variety of unit milieu stresses were videotaped. These were then edited together and played back at staff conference. This intervention increased staff awareness of unit stresses, facilitated discussion abo...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(86)90058-7
更新日期:1986-01-01 00:00:00
abstract::This study examines 100 consecutive patient referrals from a general medical clinic to psychiatric social work. While much has been written from a theoretical or anecdotal perspective on the contribution of social work to medical care, there have been relatively few attempts to look in detail at actual practices. Of t...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(84)90074-4
更新日期:1984-04-01 00:00:00
abstract::Issues of suicidal ideation, life-threatening behavior, and vulnerability in cancer patients are addressed. A review of pertinent literature is presented, including the areas of: suicide as a taboo topic; incidence of suicide in cancer patients; identifying patients' suicide potential; and suicide as coping behavior. ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(79)90055-0
更新日期:1979-07-01 00:00:00
abstract::Successful operation of a medical-psychiatry unit requires special considerations in nursing staff development and facility design. This article will discuss in detail issues related to the selection, training, and development of a medical-psychiatry unit nursing staff. Organizational details regarding establishing sc...
journal_title:General hospital psychiatry
pub_type: 更正并重新发布的文章,杂志文章
doi:10.1016/0163-8343(89)90056-x
更新日期:1989-03-01 00:00:00
abstract::Diligence in the interpretation of results is essential as information gained from the psychiatric patient's history might often be restricted. Nonobservance of established guidelines may lead to a wrong diagnosis, induce a false therapy and result in life-threatening situations. Communication errors between hospitals...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2010.03.002
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:Special observation (the allocation of nurses to watch over nominated patients) is a method of preventing patients harming themselves. This study assessed the relationship between constant special observation (keeping a patient within eyesight or reach) and rates of self-harm on acute psychiatric wards. METH...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2009.05.008
更新日期:2009-11-01 00:00:00
abstract::Little is known about which factors may adversely affect response to psychotherapy in diabetic patients with major depression. We studied the relationship of various demographic, diabetes, and depression characteristics to change in depression in 42 patients with type 2 diabetes who completed a randomized clinical tri...
journal_title:General hospital psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0163-8343(98)00039-5
更新日期:1998-09-01 00:00:00
abstract:INTRODUCTION:Chemical restraint is controversial. Appropriate use is ill-defined and chemical restraint may be overutilized. During the period of an unrelated observational study for patients with acute psychomotor agitation in a psychiatric emergency service, we noticed a significant reduction in the number of involun...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2006.06.001
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:Paliperidone-associated motor tics. METHOD:Case report. RESULTS:We report a 30-year-old man with schizophrenia who developed motor tics (eye blinking) after treatment of paliperidone up to 15 mg daily. CONCLUSION:Tic-like symptoms, from simple eye blinking to complex Tourette-like syndrome, may occur duri...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.01.003
更新日期:2014-05-01 00:00:00
abstract::Systematic assessment of the effect of clinical research studies on child and parent participants has been limited. Such assessment could provide an empirical basis for the ethical conduct of research, assisting investigators and institutional review boards in balancing the need for sound research with the need to pro...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(02)00200-1
更新日期:2002-09-01 00:00:00
abstract::The Ras-Raf-mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK cascade is important in the intra-cellular transduction of neurotransmitters, such as dopamine and glutamate. Sorafenib (Nexavar), a multi-kinase inhibitor targeting Raf kinase, vascular endothelial growth factor ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2012.03.001
更新日期:2014-07-01 00:00:00
abstract::The medical-psychiatric unit concept has been the most important influence in the development of general hospital inpatient psychiatry in the last decade. This concept and style of unit organization is reviewed in the context of the history of general hospital inpatient psychiatry. It is suggested that elements of the...
journal_title:General hospital psychiatry
pub_type: 杂志文章,评审
doi:10.1016/0163-8343(94)90083-3
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Many patients treated in the emergency department (ED) for non-psychiatric complaints have elevated suicide risk. Universal screening can detect occult suicide risk, but gold standard risk measurement tools, such as the Beck Scale for Suicidal Ideation (BSS), are too long and cumbersome for ED use. OBJECTIV...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2018.08.004
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:Patients with acute-on-chronic liver failure (ACLF) experience long-term chronic liver diseases plus an acute liver function decompensation. This study aimed to determine whether psychological symptoms in patients with hepatitis B virus (HBV)-related ACLF differ from those with other chronic liver diseases a...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2011.11.012
更新日期:2012-05-01 00:00:00