Abstract:
OBJECTIVES:Patients with acute-on-chronic liver failure (ACLF) experience long-term chronic liver diseases plus an acute liver function decompensation. This study aimed to determine whether psychological symptoms in patients with hepatitis B virus (HBV)-related ACLF differ from those with other chronic liver diseases and to identify which factors could predict psychological impairment in liver patients. METHODS:This was a paired case-control study. A total of 120 inpatients, including 40 cases for HBV-related ACLF, 40 paired controls for HBV-related cirrhosis and 40 paired controls for chronic hepatitis B (CHB), as well as 40 paired healthy controls were studied. RESULTS:A high proportion of patients with HBV-related ACLF were classified as Child's stage C. The prevalence of depression in patients with HBV-related ACLF was significantly higher than in CHB patients and healthy controls, but was equivalent to patients with HBV-related cirrhosis. Patients with HBV-related ACLF had significantly higher level of self-esteem than those with HBV-related cirrhosis. However, there was no significant difference among the three liver patient groups and healthy controls in anxiety and suicide intent. Lower education level, anxiety, poor sleep quality and greater severity of disease were associated with elevated depression. CONCLUSIONS:Patients with HBV-related ACLF and cirrhosis are at higher risk of depression. It appears that severity of liver disease measured by Child-Pugh class, rather than additional acute liver function decompensation, significantly predicted depression among liver patients.
journal_name
Gen Hosp Psychiatryjournal_title
General hospital psychiatryauthors
Duan Z,Kong Y,Zhang J,Guo Hdoi
10.1016/j.genhosppsych.2011.11.012subject
Has Abstractpub_date
2012-05-01 00:00:00pages
276-81issue
3eissn
0163-8343issn
1873-7714pii
S0163-8343(11)00370-7journal_volume
34pub_type
杂志文章abstract:BACKGROUND:Adolescent depression has been shown to be associated with later development of obesity. The purpose of this study was to examine the association between depressive symptoms and obesity with progressive pubertal development. METHODS:We conducted an analysis of the association between depressive symptoms and...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2006.03.007
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVES:The majority of VA patient suicides are completed with firearms. Interventions that delay patients' gun access during high-risk periods may reduce suicide, but may not be acceptable to VA stakeholders or may be challenging to implement. Using qualitative methods, stakeholders' perceptions about gun safety an...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2012.07.012
更新日期:2012-11-01 00:00:00
abstract::We describe a schizophrenic man whose lack of pain and related objective signs of a perforated small bowel led to a delay in diagnosis and surgical intervention. A review of the literature suggests that both psychodynamic and specific biologic factors can produce atypical presentations in psychotic patients with illne...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(90)90050-m
更新日期:1990-09-01 00:00:00
abstract:OBJECTIVE:History of prolonged traumatization has been associated with reduced quality of life (QoL) and difficulties in coping with major life-threatening conditions. We assessed the association between the impact of Holocaust experience (posttraumatic symptoms) and QoL of patients before and after an open heart surge...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2004.06.005
更新日期:2004-11-01 00:00:00
abstract::A number of reports have suggested that some cases of multiple personality disorder might be due to temporal lobe epileptic discharges. We have administered a structured interview, the Dissociative Disorders Interview Schedule, to 20 subjects with multiple personality disorder, 20 with complex partial seizures, and 28...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(89)90026-1
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:This study presents the psychometric properties of a brief measure to assess beliefs about psychotropic medications and psychotherapy among patients with anxiety disorders. METHOD:Data were collected on a large sample of primary care patients with a range of anxiety disorders, as part of the Collaborative Ca...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2005.05.005
更新日期:2005-09-01 00:00:00
abstract::Cannabis in its various forms has been known since time immemorial, the use of which has been rising steadily in India. 'Bad trips' have been documented after cannabis use, manifestations ranging from vague anxiety and fear to profoundly disturbing states of terror and psychosis. Cannabis is known to affect various ne...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2013.06.010
更新日期:2013-11-01 00:00:00
abstract::We report that infertile women in Japan as well as in the Western world have high levels of emotional distress, anxiety, and depression. The reasons for anxiety and depression in infertile women are easy to presume but remain unclear. We conducted the present study to assess the relationship between the anxiety and de...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2004.05.002
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Many patients treated in the emergency department (ED) for non-psychiatric complaints have elevated suicide risk. Universal screening can detect occult suicide risk, but gold standard risk measurement tools, such as the Beck Scale for Suicidal Ideation (BSS), are too long and cumbersome for ED use. OBJECTIV...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2018.08.004
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To assess the following among women hospitalized antenatally due to high-risk pregnancies: (1) rates of depression symptoms and anxiety symptoms, (2) changes in depression symptoms and anxiety symptoms and, (3) rates of mental health treatment. METHODS:Sixty-two participants hospitalized for high-risk obstet...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2014.07.011
更新日期:2014-11-01 00:00:00
abstract::Detection of cognitive impairment among hospitalized older individuals has shown to be insufficient. A point prevalence study in two geriatric hospitals in Helsinki, Finland, was performed among 219 acutely ill individuals over 70 years to assess the detection of dementia and delirium. Documentation of dementia and de...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2003.08.003
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To investigate longitudinal associations of burnout with heart rate variability (HRV) in patients after their first events of acute coronary syndrome (ACS). METHODS:In total, two hundred eight patients participated in this one-year follow-up study. On the day before discharge, their personal burnout level wa...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2018.05.008
更新日期:2018-01-01 00:00:00
abstract::Psychiatric morbidity among 240 pregnant women attending an antenatal unit was assessed by a two-stage screening procedure, using the General Health Questionnaire (GHQ-30) and Present State Examination Schedule (PSE). The prevalence of psychiatric morbidity was found to be significantly associated with younger age (< ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(93)90109-2
更新日期:1993-03-01 00:00:00
abstract::Bromocriptine, an ergot alkaloid dopamine agonist, is a recent common treatment for suppression of lactation in postpartum women. A case is presented of a postpartum woman prescribed bromocriptine for suppression of lactation who developed hypertension, headaches, blurry vision, seizures, and pituitary hemorrhage. Dif...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(91)90131-f
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:The objective was to describe continuity of care approaches for psychiatric emergencies in the emergency department. METHODS:A national survey of all 138 academic emergency departments in the United States was conducted. RESULTS:Most emergency physicians (81%) had no systematic method for identifying psychi...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2011.05.020
更新日期:2011-11-01 00:00:00
abstract::The following case presents a 22-year-old woman with relapsing polychondritis and depression treated in liaison, consultation, and outpatient settings by one psychiatrist using a variety of techniques. The discussion focuses on the implications of the case for integrated medical model and psychotherapeutic care, and f...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(83)90010-5
更新日期:1983-12-01 00:00:00
abstract::A 63-year-old married man with idiopathic terminal cardiomyopathy was admitted to the medical service for treatment of advanced heart failure. A psychiatric consultation was requested to assist the medical treatment team in dealing with the patient's abusive behavior. The case is presented and discussed within the con...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(92)90099-v
更新日期:1992-07-01 00:00:00
abstract::Outpatient consultation-liaison (C-L) psychiatry has been beset with problems concerning funding and patient acceptance. Though the consultation, liaison, and referral clinic models for outpatient C-L psychiatry each offer advantages, they have not conquered these fundamental problems. This paper introduces the multid...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(93)90005-9
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:Psychological morbidity in both patients and family members related to the intensive care unit (ICU) experience is an often overlooked, and potentially persistent, healthcare problem recognized by the Society of Critical Care Medicine as Post-intensive Care Syndrome (PICS). ICU diaries are an intervention in...
journal_title:General hospital psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.genhosppsych.2020.06.017
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To characterize temporal trends and outcomes of invasive mechanical ventilation (MV) for people with severe mental disorders (SMD) admitted due to natural causes. METHODS:We identified all 224,507 hospitalizations of patients aged 15-69 who underwent MV in Spain between 2000 and 2015, excluding poisonings an...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2020.04.007
更新日期:2020-01-01 00:00:00
abstract::Systematic assessment of the effect of clinical research studies on child and parent participants has been limited. Such assessment could provide an empirical basis for the ethical conduct of research, assisting investigators and institutional review boards in balancing the need for sound research with the need to pro...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/s0163-8343(02)00200-1
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:Optimism is prospectively and independently associated with superior cardiac outcomes, but there has been minimal study of optimism-specific interventions in persons with cardiovascular illness. We aimed to examine the feasibility and impact of an optimism-promoting program among patients with heart disease i...
journal_title:General hospital psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.genhosppsych.2017.12.004
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:Missed appointments are associated with poorer health outcomes. We predicted that compared to secure attachment style, fearful and dismissing attachment styles would be associated with greater number of missed primary care visits in patients with diabetes. METHODS:In patients with diabetes from nine health m...
journal_title:General hospital psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/j.genhosppsych.2005.07.004
更新日期:2006-01-01 00:00:00
abstract::Parasuicide is usually associated with low suicidal intent and research data show that rising rates remain a challenging clinical and research problem. Hopelessness, a core characteristic of depression, appears to be the link between depression and suicidal behavior in high-risk patients. Previous research in this reg...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(88)90021-7
更新日期:1988-05-01 00:00:00
abstract::Two patients with an acute organic brain syndrome and accompanying neurological symptoms are described. Extensive work up showed that both patients suffered from small-cell lung cancer. Cerebral metastases were absent. Following chemotherapy and radiotherapy to the primary tumor one of the two patients showed a comple...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(89)90132-1
更新日期:1989-11-01 00:00:00
abstract:OBJECTIVE:The objective was to estimate the prevalence of both dementia and depression among community-dwelling older Americans and to determine if hospitalization is independently associated with dementia or depression in this population. METHOD:This cross-sectional study utilized data from a nationally representativ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2013.11.008
更新日期:2014-03-01 00:00:00
abstract::As the consultation-liaison psychiatrist for a large burn service, the author investigated the undermedication for pain. This phenomenon could not be adequately explained by the staff's insensitivity, by mistaken ideas about analgesics, or by fears of iatrogenic addiction. For both patients and staff, the pain served ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(84)90026-4
更新日期:1984-10-01 00:00:00
abstract::Drawing on experiences as a Physician Advisor to the Office of Quality Assurance of the American Psychiatric Association, the author discusses process interactions endemic to peer review and presents recommendations for facilitating this necessary professional activity. ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(89)90073-x
更新日期:1989-07-01 00:00:00
abstract::Suicidal behavior is disproportionately frequent among inner-city Hispanic adolescent girls. In an attempt to generate a multifactorial set of hypotheses to explain this behavior, 33 such subjects consecutively admitted for suicidal behavior and 15 demographically identical nonsuicidal subjects were assessed by means ...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/0163-8343(91)90009-l
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:Anxiety and depressive disorders are widely prevalent, but patients are only treated in a minority of cases. In this study, the explanation of receiving mental health treatment is sought in predisposing and enabling characteristics and indicators for objective and self-perceived need. METHODS:Cross-sectional...
journal_title:General hospital psychiatry
pub_type: 杂志文章
doi:10.1016/j.genhosppsych.2008.09.011
更新日期:2009-01-01 00:00:00