Abstract：
:This report describes the background, rationale, and research plan for a comparative treatment trial of the effectiveness of paroxetine, problem-solving therapy (PST-PC), and placebo in the treatment of minor depression and dysthymia in primary care patients. Patients were recruited from a variety of primary care practice settings in four separate geographic locations (Hanover, New Hampshire; Pittsburgh, Pennsylvania, San Antonio, Texas; and Seattle, Washington). Patients were randomly assigned to each of the three intervention conditions the medication/placebo conditions were double-blinded. The treatment trial was 11 weeks, with independent assessments of patient clinical status at baseline, 6 weeks, and 11 weeks. There was a follow-up at 25 weeks. Since there are relatively few placebo-controlled trials in primary care settings on patients with these disorders, the background of this project and a description of it are presented at this time, prior to the availability of outcome data, to provide methodological detail and to increase awareness in the research community of this treatment trial, with results to appear subsequently.
journal_name
Gen Hosp Psychiatryjournal_title
General hospital psychiatryauthors
Barrett JE,Williams JW Jr,Oxman TE,Katon W,Frank E,Hegel MT,Sullivan M,Schulberg HCdoi
10.1016/s0163-8343(99)00023-7subject
Has Abstractpub_date
1999-07-01 00:00:00pages
260-73issue
4eissn
0163-8343issn
1873-7714pii
S0163-8343(99)00023-7journal_volume
21pub_type
临床试验,杂志文章,随机对照试验,评审abstract：:The diagnosis of psychopathology among geriatric acute inpatients requires comprehensive evaluation. To our knowledge, no recently published papers in the geriatric psychiatry literature have systematically examined diagnostic changes during single admissions. We reviewed the charts of 159 patients consecutively admit...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/s0163-8343(00)00118-3
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:To investigate the differences in depressive mood and quality of life in patients with between functional dyspepsia (FD), irritable bowel syndrome (IBS), and FD-IBS overlap as diagnosed based on Rome III criteria. METHODS:The subjects completed a questionnaire based on Rome III criteria, the Beck Depressive ...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2010.05.002
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION:Chemical restraint is controversial. Appropriate use is ill-defined and chemical restraint may be overutilized. During the period of an unrelated observational study for patients with acute psychomotor agitation in a psychiatric emergency service, we noticed a significant reduction in the number of involun...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2006.06.001
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVE:We describe a patient with prodromal dementia with Lewy bodies (DLB) presenting with drug-induced visual hallucinations (VHs). CASE REPORT:A 78-year-old woman complained of daytime recurrent VHs characterized by seeing her face and arms covered in fur and viewing moustaches on her daughter's face. VHs starte...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2013.02.005
更新日期：2013-11-01 00:00:00
abstract：:Minicomputer systems have been designed for researchers who have no prior computer experience and, therefore, require no computer training, that is, programming knowledge. Such systems allow immediate access to the data, their retrieval, reduction, and analysis, and the retention of direct control over the data base b...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/0163-8343(85)90021-0
更新日期：1985-04-01 00:00:00
abstract：BACKGROUND:Oral loading with the delayed release formulation of divalproex sodium is widely used for the treatment of patients with acute mania and produces rapid attainment of therapeutic serum levels. Recently, an extended release formulation of divalproex sodium (divalproex ER) was approved for treatment of migraine...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2005.02.001
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:The treatment of agitation in drug- and alcohol-using emergency patients is understudied. METHOD:We performed a retrospective chart review of 105 agitated emergency department patients who received either intramuscular (IM) haloperidol or IM olanzapine, comparing prescribing patterns, level of agitation, res...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2010.04.005
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:Previous epidemiologic studies have documented a link between anxiety disorders and ulcer among adults. Few studies have examined these associations over time and little is understood about the pathways underlying these relationships. METHOD:Data were drawn from n = 2101 adult participants in the Midlife Dev...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2014.07.005
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:This study examined if associations between body mass index (BMI) and mental and physical health were independent of genetic and familial factors. METHOD:Data from 2831 twins (66% female) were used in an epidemiological co-twin control design with measures of BMI and mental and physical health outcomes. Gene...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2013.04.004
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:This naturalistic prospective study explored the predictors of laboratory test ordering in a psychiatric emergency department. METHODS:We used a standardized questionnaire to collect clinical and nonclinical features in 527 consecutive patients. RESULTS:Test ordering was independently predicted by age, spok...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2008.02.005
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVE:Demoralization, a state of lowered morale and poor coping, has a prevalence of 13-18% among patients with advanced cancer. We surveyed clinicians' perspectives of the utility of "with demoralization" as a diagnostic specifier for adjustment and depressive disorders. METHOD:Using comparative clinical vignette...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2017.01.007
更新日期：2017-05-01 00:00:00
abstract：:Two patients with an acute organic brain syndrome and accompanying neurological symptoms are described. Extensive work up showed that both patients suffered from small-cell lung cancer. Cerebral metastases were absent. Following chemotherapy and radiotherapy to the primary tumor one of the two patients showed a comple...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/0163-8343(89)90132-1
更新日期：1989-11-01 00:00:00
abstract：:This study examines the recognition and treatment of emotional distress in physically healthy primary care patients who perceive themselves to be in fair or poor physical health. Patients (N = 892) from three private primary care practices completed a mental health screening form prior to their medical visit which inc...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/0163-8343(95)00023-k
更新日期：1995-05-01 00:00:00
abstract：:The ventral striatum has been assigned a major role in addictive behavior. In addition, clinical lesion studies have described involvement of the insula and globus pallidus. To the best of our knowledge, this is the first report of alleviation of alcohol and nicotine addiction after a cerebrovascular incident in the d...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2012.01.008
更新日期：2012-11-01 00:00:00
abstract：:Children (N = 110) hospitalized on a child psychiatric unit improved significantly in psychological functioning at discharge and 1- and 6-months follow-up relative to their functioning at admission. Children who were more impaired at admission made more progress during admission but were more impaired at follow-up tha...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/s0163-8343(01)00153-0
更新日期：2001-09-01 00:00:00
abstract：:The authors explore the difficulties present in the capacity evaluation of patients with strong religious beliefs. The article reviews the legal protection for treatment refusal on religious grounds as well as psychiatry's approach to religion. Clinical cases encountered in an urban hospital are presented to highlight...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/0163-8343(96)00003-5
更新日期：1996-05-01 00:00:00
abstract：:Hashimoto's encephalopathy (HE), which carries kaleidoscopic clinical presentations, is easily misdiagnosed in clinical practice. Early diagnosis and prompt initiation of steroid therapy are associated with good prognosis. We describe a 50-year-old female patient who had subclinical hypothyroidism and who presented he...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2014.01.006
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Adolescent depression has been shown to be associated with later development of obesity. The purpose of this study was to examine the association between depressive symptoms and obesity with progressive pubertal development. METHODS:We conducted an analysis of the association between depressive symptoms and...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2006.03.007
更新日期：2006-07-01 00:00:00
abstract：:Liaison psychiatry is traditionally practiced on the medical and surgical floors of the general hospital. The need for liaison psychiatry on the inpatient psychiatric unit as opposed to its usual setting was realized when the medical care requirements of hospitalized psychiatric patients was assessed. In many general ...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/0163-8343(80)90028-6
更新日期：1980-06-01 00:00:00
abstract：:The validity and clinical use of a recently developed instrument to assess health care needs of patients with a physical illness, called INTERMED, is investigated. The INTERMED combines data reflecting patients' biological, psychological, and social characteristics with information on health care utilization character...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/s0163-8343(98)00061-9
更新日期：1999-01-01 00:00:00
abstract：:Drawing on experiences as a Physician Advisor to the Office of Quality Assurance of the American Psychiatric Association, the author discusses process interactions endemic to peer review and presents recommendations for facilitating this necessary professional activity. ...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/0163-8343(89)90073-x
更新日期：1989-07-01 00:00:00
abstract：:Bupropion, a dual norepinephrine and dopamine reuptake inhibitor, has been approved by the United States Food and Drug Administration for the treatment of major depressive disorder. The most common treatment-emergent adverse events reported with bupropion were headache, dry mouth, nausea and agitation. The following i...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2011.01.010
更新日期：2011-07-01 00:00:00
abstract：:Several predictors of the course of depression and generalized anxiety have been identified. Whether these predictors provide a solid basis for primary care physicians (PCPs) to give an accurate prognosis remains unclear. A parallel study showed modest agreement between PCP prognosis and observed course (kappa< or = 0...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/s0163-8343(02)00183-4
更新日期：2002-05-01 00:00:00
abstract：:Thirty-one maintenance hemodialysis patients were observed for a six-month period. Seven of these patients (22.6%) were severe and persistent abusers of the hemodialysis diet. Because there are serious, even lethal, consequences of the sequelae of hemodialysis diet abuse such as fluid overload and/or hyperkalemia, thi...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/0163-8343(81)90052-9
更新日期：1981-06-01 00:00:00
abstract：:Both electroconvulsive therapy (ECT) and paliperidone (PLP) can induce, though infrequently, severe cardiac side-effects. Thus far, no studies are available on the cardiac safety of their co-administration. We report on the cardiac safety of the ECT-PLP combination in nine female inpatients who underwent this treatmen...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2010.09.012
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:This study aims to compare the prevalence of obsessive-compulsive spectrum disorders (OCSD) in psychiatric outpatients with and without a history of rheumatic fever (RF). METHODS:An analytical cross-sectional study assessing a large sample of consecutive psychiatric outpatients at a Brazilian private practic...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2008.11.003
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:Over the last decade, charcoal burning has become a common method of suicide in Taiwan; however, the underlying psychiatric diagnoses and gender differences have yet to be examined. METHODS:We conducted a retrospective chart review on inpatients after suicide attempt by charcoal burning during 2000-2010. The...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2012.03.015
更新日期：2012-09-01 00:00:00
abstract：:Preoperative risk factors of postoperative delirium were evaluated in 260 patients admitted for open heart surgery. The incidence of delirium was 11.5%. Independent predictors included cognitive impairment, atrial fibrillation, a history of peripheral vascular disease major depression and advanced age. Aforementioned ...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/j.genhosppsych.2006.08.007
更新日期：2006-11-01 00:00:00
abstract：INTRODUCTION:Catatonia is classically associated with psychiatric conditions but may occur in medical and neurologic disorders. Status epilepticus (SE) is a seizure lasting more than five minutes or two or more seizures within a five-minute period without interictal recovery of consciousness. Non-convulsive status epil...
journal_title：General hospital psychiatry
pub_type： 杂志文章,评审
doi：10.1016/j.genhosppsych.2020.11.008
更新日期：2021-01-01 00:00:00
abstract：:Issues of suicidal ideation, life-threatening behavior, and vulnerability in cancer patients are addressed. A review of pertinent literature is presented, including the areas of: suicide as a taboo topic; incidence of suicide in cancer patients; identifying patients' suicide potential; and suicide as coping behavior. ...
journal_title：General hospital psychiatry
pub_type： 杂志文章
doi：10.1016/0163-8343(79)90055-0
更新日期：1979-07-01 00:00:00
