Abstract:
:We have reported two cases involving bacteremic patients who failed to respond adequately to the investigational agent daptomycin. Despite apparent sensitivity of the organisms, therapy was unsuccessful in both patients using the recommended dosage. The sponsor of daptomycin is currently reevaluating the recommendation and may be revising their dosage guidelines in the future.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Garrison MW,Rotschafer JC,Crossley KBdoi
10.1097/00007611-198911000-00018subject
Has Abstractpub_date
1989-11-01 00:00:00pages
1414-5issue
11eissn
0038-4348issn
1541-8243journal_volume
82pub_type
杂志文章abstract:OBJECTIVES:Guidelines have recommended that risk stratification be performed in patients diagnosed with an acute pulmonary embolism (PE). No study has described the use of risk stratification in routine clinical practice. The purpose of this study was to measure the frequency and impact of risk stratification on treatm...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0000000000000053
更新日期:2014-02-01 00:00:00
abstract::The risk of suicidal behavior associated with antidepressant treatment is an issue of debate and concern. The US FDA has required that antidepressants carry a black box warning that there may be a risk of suicidal ideations in depressed pediatric patients treated with these medications, and recently extended the warni...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3181a918bd
更新日期:2009-07-01 00:00:00
abstract::A previously healthy 38-year-old man was stung multiple times by yellow jackets without any signs of anaphylaxis being observed. An electrocardiogram taken 16 hours later revealed episodes of wandering atrial pacemaker, junctional rhythm, and intermittent premature ventricular contractions. These arrhythmias disappear...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197904000-00030
更新日期:1979-04-01 00:00:00
abstract::A poorly understood significant drug-drug interaction compounded by ineffective communication among providers at times of care transition most likely contributed to multiple thromboembolic events in an 81-year-old patient. Increased awareness of drug interactions with direct oral anticoagulants (DOACs), as well as imp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000926
更新日期:2019-02-01 00:00:00
abstract::An aberrant internal carotid artery (ICA) in the middle ear is rare. If unrecognized, it may lead to massive hemorrhage or other catastrophic results during even a minor surgical procedure of the tympanic membrane or middle ear. Recognition of this entity is particularly significant to the primary care or emergency de...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199412000-00014
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND:Patient comfort is an important part of laceration repair. METHODS:The study was a randomized single-blind cross-over trial in which each participant received 250 ml warmed and 250 ml room temperature saline irrigation in simple linear wounds after a local anesthetic was instilled. The solutions and the ord...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.SMJ.0000056657.63336.6C
更新日期:2003-05-01 00:00:00
abstract::Transchondral talar dome fractures are a rare but not unknown cause of continued disability following a "sprained ankle." The diagnosis is made with standard ankle roentgenograms and an awareness of the lesion. Surgical treatment is recommended in acute and chronic cases, based on the amount of displacement of the fra...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198405000-00007
更新日期:1984-05-01 00:00:00
abstract::A case of ruptured interstitial pregnancy is reported, along with review of the literature. Although sonography did not differentiate between interstitial and intrauterine pregnancy, I believe it will prove to be one of the most accurate diagnostic aids in detecting this condition. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198009000-00044
更新日期:1980-09-01 00:00:00
abstract::We have described massive intermittent intestinal hemorrhage due to a vascular anomaly in an ileal duplication cyst in a 30-year-old man. This unusual case illustrates that these lesions disguise themselves symptomatically and must be considered in the differential diagnosis of gastrointestinal bleeding. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198412000-00039
更新日期:1984-12-01 00:00:00
abstract::Some cultural and epidemiologic factors leading to a new emphasis on self-care in chronic illness are reviewed and current applications of self-care in medicine are illustrated with examples. Emotional and behavioral aspects of self-care programs are detailed with special attention to compliance, family involvement, a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198309000-00016
更新日期:1983-09-01 00:00:00
abstract::A case of carcinoma of the ampulla of Vater was diagnosed preoperatively by percutaneous transhepatic cholangiography using the Chiba needle. A dilated pancreatic duct is a radiologic sign diagnostic of early ampullary carcinoma. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197912000-00051
更新日期:1979-12-01 00:00:00
abstract::A hallmark of the clinical syndrome of thrombotic thrombocytopenic purpura (TTP) is evidence of microangiopathic hemolytic anemia. The presence of schistocytes on the peripheral blood smear, elevated plasma lactic dehydrogenase, and decreased haptoglobin concentration are used as evidence of microangiopathic hemolytic...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000136231.83564.F6
更新日期:2005-03-01 00:00:00
abstract::The role of the otolaryngologist in the diagnosis and management of cerebrospinal fluid rhinorrhea is discussed. One hundred eight cases of cerebrospinal rhinorrhea were studied with emphasis on cause, localization, and treatment. Extracranial approaches produce minimal morbidity and should be considered as possible t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197512000-00015
更新日期:1975-12-01 00:00:00
abstract::We have presented an unusual case of CJD in which the magnetic resonance images obtained four months before death revealed high signal intensity in the caudate nuclei bilaterally. These findings correspond to severe involvement of this region at autopsy. This radiologic pattern has not generally been included in the d...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::Reported is the fifth known case of Addison's disease due to adrenal involvement by North American blastomycosis (Blastomyces dermatitidis infection). The fact that amphotericin B therapy precipitated an addisonian crisis suggests that patients with disseminated blastomycosis should have their adrenal function and res...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197707000-00028
更新日期:1977-07-01 00:00:00
abstract:OBJECTIVES:To determine whether prolonged length of stay (pLOS) in ischemic stroke is related to delays in discharge disposition arrangement. METHODS:We designed a retrospective study to compare patients with acute ischemic stroke who experienced pLOS to those who did not experience pLOS. Patients who have had acute i...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0000000000000036
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:The problem of high body mass index (BMI) for age in the Head Start population in Texas is of great concern. The primarily Mexican American population is at high risk for diabetes and cardiovascular disease. This study examines the prevalence of elevated BMI for age in the Head Start population in a sampling ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181faeb4d
更新日期:2010-12-01 00:00:00
abstract::Results in three series of spinal fusions with Harrington instrumentation for scoliosis were compared. Patient ages ranged from 9 to 22 years, and follow-up from 12 to 105 months. Cylindrical inlay facet grafting was done in all cases. Supplemental heterologous bone was used in the first series of 51 cases, autologous...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197702000-00025
更新日期:1977-02-01 00:00:00
abstract::As our population ages, the incidence and prevalence of Alzheimer disease (AD) will increase dramatically. A number of therapies have been investigated for the treatment and prevention of AD. Clinicians should be prepared to provide evidence-based answers to inquiries regarding AD treatment. There is insufficient evid...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.SMJ.0000166671.86815.C1
更新日期:2005-06-01 00:00:00
abstract::A woman with chronic hemoptysis as her only complaint had extensive testing and did not respond to antibiotic therapy. Radiologic examination of the sinuses identified a mass which, on surgical exploration, was found to be the result of a fungus, Pseudallescheria boydii. Although this fungus is known to be a cause of ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199507000-00021
更新日期:1995-07-01 00:00:00
abstract::Despite a wealth of publications extolling the virtues of the double contrast barium enema (DCBE), it is clear that change is only gradual and that in many institutions the single contrast, full column barium enema (BE) is still the routine method of colonic investigation. Much of this may be due to a persistent belie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198201000-00012
更新日期:1982-01-01 00:00:00
abstract::We have described a patient in whom complete regression of pulmonary metastases from renal cell carcinoma (RCC) followed treatment with medroxy-progesterone acetate (Depo-Provera). Although the reported rate of objective response to progesterone therapy in RCC is only 10% to 15%, the occasionally dramatic results, esp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198002000-00034
更新日期:1980-02-01 00:00:00
abstract::We have described a patient with small cell cancer of the lung manifested as the Eaton-Lambert syndrome. Primary therapy proved effective in reversing the syndrome, whereas anticholinesterase agents did not. This case illustrates the value of primary therapy for the tumor-produced syndrome and the need to avoid losing...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198502000-00020
更新日期:1985-02-01 00:00:00
abstract::Spontaneous bacterial peritonitis (SBP) is a common complication in patients with cirrhosis of the liver. The organisms most commonly involved in this infection are gram-negative bacteria like Escherichia coli and Klebsiella pneumoniae, and gram-positive bacteria like Streptococcus pneumoniae and Staphylococcus aureus...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-10-01 00:00:00
abstract::We surveyed 1528 first-year students at the University of Virginia, 1 month after their arrival on campus, who had used alcohol at some time in their lives. Our survey was designed to identify alcohol and cocaine use, and related psychosocial patterns. Men drank more and more often than women. Our data suggest that bo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199101000-00005
更新日期:1991-01-01 00:00:00
abstract::While fish consumption is considered a component of a heart-healthy diet, many illnesses have been associated with eating contaminated fish. The authors describe two cases of muscle weakness and rhabdomyolysis that occurred after eating salmon. Cases of rhabdomyolysis and muscle weakness after consumption of fresh wat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181583673
更新日期:2007-11-01 00:00:00
abstract::Patients with non-insulin-dependent diabetes mellitus (NIDDM) failing to respond to therapy with a maximum dose of glyburide (GB) or glipizide (GZ) are often given a trial of the alternate second-generation sulfonylurea (SGS) before insulin therapy is considered. The efficacy of this therapeutic maneuver has not been ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199106000-00017
更新日期:1991-06-01 00:00:00
abstract::A controlled trial of treatment of chronic osteomyelitis caused by Staphylococcus aureus compared nafcillin alone with nafcillin plus rifampin for a six-week period. Treatment was well tolerated, the only adverse effect being mild neutropenia in four of 18 patients; no toxicity was observed from rifampin. Eight of ten...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/00007611-198608000-00008
更新日期:1986-08-01 00:00:00
abstract:BACKGROUND:The effects of chronic diuretic use on serum homocysteine and its metabolic cofactors vitamin B6, vitamin B12, and red blood cell (RBC) folate have not been well studied. METHODS:Blood samples from 17 hypertensive patients receiving long-term diuretic therapy and 17 hypertensive patients not taking diuretic...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/00007611-199909000-00003
更新日期:1999-09-01 00:00:00
abstract::We have described a case of cyclic neutropenia and pregnancy. Although many such cases exist, we believe this is the first time the association has been documented. In this patient, pregnancy had a mitigating effect on the symptoms caused by cyclic neutropenia. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198804000-00031
更新日期:1988-04-01 00:00:00