In vivo imaging of adipose-derived mesenchymal stem cells in female nude mice after simulated childbirth injury.

abstract：:The present study aimed to evaluate whether thymosin α1 (Tα1) increases survival rates through the improvement of immunofunction and inhibition of hepatocyte apoptosis in rats with acute liver failure (ALF). A total of 25 rats were randomly divided into the control group (CG), the model group (MG) and the treatment gr...

journal_title：Experimental and therapeutic medicine

authors： Yang X,Chen Y,Zhang J,Tang T,Kong Y,Ye F,Zhang X,Liu X,Lin S

更新日期：2018-04-01 00:00:00

abstract：:The aim of the present study was to evaluate and compare the effects of single- and two-dose low-level laser therapy (LLLT) on the postoperative swelling, trismus and pain of patients undergoing extraction of impacted mandibular third molars. In addition, edema was volumetrically measured with a 3dMD face system. A to...

journal_title：Experimental and therapeutic medicine

authors： Koparal M,Kucuk AO,Alan H,Asutay F,Avci M

更新日期：2018-04-01 00:00:00

abstract：:Macrophage autophagy has a protective role in the development of atherosclerosis; however, it turns dysfunctional in advanced lesions with an increase in p62/sequestosome-1 protein. Little is known about the role and significance of p62 accumulation in atherosclerosis. The present study investigated the association be...

journal_title：Experimental and therapeutic medicine

authors： Ning H,Liu D,Yu X,Guan X

更新日期：2017-12-01 00:00:00

abstract：:The objective of the present study was to observe the therapeutic effect of radiation delivered via a 32P source on Graves' ophthalmopathy. A32P solution was injected into a 10-ml vacuum flask held inside a lead container. A window was cut in the lead, generating a treatment beam. Radiation was given to four areas: Th...

journal_title：Experimental and therapeutic medicine

authors： Hao HT,Wang Y,Wang X,Luan S,Cui J,Chen Y,Cui YL

更新日期：2017-10-01 00:00:00

abstract：:Drug eruption is a major problem of adverse drug reactions and may present as variform clinical manifestations. Toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) are relatively rare severe drug eruptions. It has rarely been reported that AGEP overlaps or mimics TEN, while no purule...

journal_title：Experimental and therapeutic medicine

authors： Liu LF,Yan JL,Wang JY,Chen JS,Cai SQ,Lao LM,Zheng M

更新日期：2013-04-01 00:00:00

abstract：:Serum thymidine kinase 1 (STK1) is a reliable proliferation marker in most solid tumors, including gastric cancer. The aim of this study was to evaluate whether STK1 levels are related to the tumor response to chemotherapy and survival in advanced gastric cancer. The results showed that the average STK1 level in patie...

journal_title：Experimental and therapeutic medicine

authors： Liu Y,Ling Y,Qi Q,Tang Y,Xu J,Tong Z,Sheng G,Yang Q,Pan Y

更新日期：2011-11-01 00:00:00

abstract：:Gamboge, the dried resin secreted by Garcinia maingayii (gambogic tree), was previously demonstrated to exert anti-inflammatory effects. The present study examined the effects of gambogic acid, the major active constituent of gamboge, on myocardial infarction (MI) and inflammation in a rat model and explored the possi...

journal_title：Experimental and therapeutic medicine

authors： Na D,Aijie H,Bo L,Zhilin M,Long Y

更新日期：2018-02-01 00:00:00

abstract：:The effects of atrial fibrillation on complications and prognosis of patients receiving emergency percutaneous coronary intervention after acute myocardial infarction (AMI) were investigated. Eighty AMI patients treated with interventional vascular recanalization in the Affiliated Hospital of Weifang Medical Universit...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Zhang L,Zheng H,Chen H

更新日期：2018-10-01 00:00:00

abstract：:Endotoxin tolerance is an immunohomeostatic reaction to reiterant lipopolysaccharide (LPS) exposure that maintains a state of altered responsiveness in immune cells, resulting in the inhibition of the pro-inflammatory response and the resolution of inflammation. Microglia constitutes the first line of defense against ...

journal_title：Experimental and therapeutic medicine

authors： Sun X,Sun J,Shao X,Feng J,Yan J,Qin Y

更新日期：2018-06-01 00:00:00

abstract：:The aim of the present study was to identify genes under the effect of transforming growth factor-β (TGF-β1), high glucose (HG) and glucosamine (GlcN) in MES-13 mesangial cells and elucidate the molecular mechanisms of diabetic nephropathy (DN). The gene expression datasets GSE2557 and GSE2558 were downloaded from the...

journal_title：Experimental and therapeutic medicine

authors： Mou X,Zhou DY,Liu YH,Liu K,Zhou D

更新日期：2019-06-01 00:00:00

abstract：:MicroRNA-155 (miR-155) is overexpressed in numerous human cancer types and has an oncogenic role. Previous study has revealed that miR-155 serves an important role in the progression of clear-cell renal cell carcinoma (ccRCC); however, the underlying mechanism was not completely clarified. The present study aimed to i...

journal_title：Experimental and therapeutic medicine

authors： Ji H,Tian D,Zhang B,Zhang Y,Yan D,Wu S

更新日期：2017-05-01 00:00:00

abstract：:The study was conducted to evaluate the relationship between the blood lactic acid (BLA) level, serum procalcitonin (PCT), C-reactive protein (CRP) and the severity and prognosis of neonatal sepsis. A retrospective analysis was conducted on 90 children with sepsis admitted into the Intensive Care Unit (ICU) of the Hub...

journal_title：Experimental and therapeutic medicine

authors： Jia Y,Wang Y,Yu X

更新日期：2017-09-01 00:00:00

abstract：:Systemic sclerosis (SSc) is a relatively rare autoimmune disease with skin and visceral involvement, having a yet unknown etiopathogenesis. Research has shown that professional exposure to various polluting chemicals such as dyes, aliphatic and aromatic organic solvents, inhalable silica dust or certain heavy metals, ...

journal_title：Experimental and therapeutic medicine

authors： Bobeica C,Niculet E,Craescu M,Halip AI,Popescu IA,Draganescu ML,Onisor C,Stefanescu B,Gheuca-Solovastru L

更新日期：2021-01-01 00:00:00

abstract：:Chronic heart disease contributes to the mortality of patients with AIDS. Although studies of left ventricular function in patients with acquired immune deficiency syndrome (AIDS) have been conducted, studies of right ventricular function are rare. The present study aimed to characterize the tricuspid annulus movement...

journal_title：Experimental and therapeutic medicine

authors： Zhu H,Yuan J,Wei C,Chen J,Wang Y

更新日期：2014-03-01 00:00:00

abstract：:Relative changes in B-type natriuretic peptide (BNP) and amino terminal pro-BNP (NT-proBNP) levels may help to assess the risk of congestive heart failure (CHF). However, whether these levels at the time of admission enable the prediction of outcomes with acute exacerbation remains unknown. The current study determine...

journal_title：Experimental and therapeutic medicine

authors： Dai Y,Yang J,Takagi A,Konishi H,Miyazaki T,Masuda H,Shimada K,Miyauchi K,Daida H

更新日期：2017-08-01 00:00:00

abstract：:Impaired glucose tolerance (IGT) is a pre-diabetic metabolic state involving heterogeneous and dynamic changes between the normal and diabetic state. The present study aimed to investigate the endocrine regulation of endothelium-dependent dysfunction in middle-aged patients with IGT and in patients with a normal gluco...

journal_title：Experimental and therapeutic medicine

authors： Liu Y,Li J,Zhang Z,Tang Y,Chen Z,Wang Z

更新日期：2014-03-01 00:00:00

abstract：:Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are an effective treatment for advanced non-small cell lung cancer. The objective of the present study was to compare the efficacy of gefitinib and erlotinib in patients with pulmonary adenocarcinoma, whose tumor EGFR mutation status was known. Pu...

journal_title：Experimental and therapeutic medicine

authors： Wu WS,Chen YM,Tsai CM,Shih JF,Chiu CH,Chou KT,Lai SL,Wu CH,Luo YH,Huang CY,Lee YC,Perng RP,Whang-Peng J

更新日期：2012-02-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is one of the most common cancer types worldwide. Previous studies have indicated that TOR signaling pathway regulator (TIPRL) is involved in the progression of NSCLC. However, the underlying mechanisms of the role of TIPRL in regulating NSCLC metastasis have remained largely elusive...

journal_title：Experimental and therapeutic medicine

authors： Xu X,Zhu H,Yang M,Zheng E,Zhou Y,Ni J,Li R,Yang Z,He T,Zhao G

更新日期：2020-03-01 00:00:00

abstract：:Following spinal cord injury in rats, FK506 is able to protect local nerve tissue, promote neural regeneration, reduce neuronal apoptosis and accelerate the recovery of spinal cord functions. Nerve growth factor (NGF) is important in the regulation of central and peripheral nerve cell regeneration, growth differentiat...

journal_title：Experimental and therapeutic medicine

authors： Chen G,Zhang Z,Wang S,Lv D

更新日期：2013-10-01 00:00:00

abstract：:Different tacrolimus (TAC) population pharmacokinetic (PPK) models have been established in various pediatric disease populations. However, a TAC PPK model for pediatric refractory nephrotic syndrome (PRNS) has not been well characterized. The current study aimed to establish a TAC PPK model in Chinese PRNS and provid...

journal_title：Experimental and therapeutic medicine

authors： Wang D,Lu J,Li Q,Li Z

更新日期：2019-05-01 00:00:00

abstract：:The activation of monocytes and macrophages is associated with steroid-resistant (SR) asthma. Interleukin-35 (IL-35) is an important anti-inflammatory cytokine, but its regulatory effects on monocytes in patients with SR asthma is not fully understood. Based on clinical response to oral prednisolone, 34 patients with ...

journal_title：Experimental and therapeutic medicine

authors： Qian L,Xu D,Xue F,Li M,Wang X,Liu G

更新日期：2020-05-01 00:00:00

abstract：:Silk fibroin (SF), chitosan (CS) and nano-hydroxyapatite (nHA) possess excellent biocompatibility, thus, these were used to construct a SF/CS/nHA composite scaffold. Previously published results identified that this material exhibited satisfactory physical and chemical properties, and therefore qualified as a repair m...

journal_title：Experimental and therapeutic medicine

authors： Ye P,Yu B,Deng J,She RF,Huang WL

更新日期：2017-12-01 00:00:00

abstract：:UNBS5162, a naphthalimide derivative, has a strong anticancer effect and low clinical hematological toxicity. UNBS5162 has been shown to have an anticancer effect in numerous cancer types, except triple negative breast cancer (TNBC). To explore this issue, TNBC MDA-MB-231 cells were selected, and the effect of UNBS516...

journal_title：Experimental and therapeutic medicine

authors： Yue X,Li M,Chen D,Xu Z,Sun S

更新日期：2018-11-01 00:00:00

abstract：:Pontocerebellar hypoplasia type 6 (PCH6) is a rare autosomal recessive disease that occurs due to mutations in the mitochondrial arginyl-tRNA synthetase 2 (RARS2) gene. To the best of our knowledge, 23 cases with relatively complete clinical data have been reported thus far. In the present study, a case with PCH6 caus...

journal_title：Experimental and therapeutic medicine

authors： Zhang J,Zhang Z,Zhang Y,Wu Y

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to investigate the role of the Rho/Rho associated coiled coil-forming protein kinase (Rock) signaling pathway in the pathogenesis of ischemic myocardial fibrosis (MF) in rats. The MF rat model was established using isoprenaline hydrochloride (ISO, 15 mg/kg). Rats were randomly divided into te...

journal_title：Experimental and therapeutic medicine

authors： Gao HC,Zhao H,Zhang WQ,Li YQ,Ren LQ

更新日期：2013-04-01 00:00:00

abstract：:The aim of the present study was to explore the effects and mechanisms of insulin on mitochondrial oxidative stress in septic acute kidney injury (AKI). Male Sprague Dawley rats were divided randomly into four groups: Control group, sham surgery group, cecal ligation and puncture (CLP) group, and CLP plus insulin grou...

journal_title：Experimental and therapeutic medicine

authors： Chen GD,Zhang JL,Chen YT,Zhang JX,Wang T,Zeng QY

更新日期：2018-04-01 00:00:00

abstract：:The aim of this meta-analysis was to investigate the accuracy of subtraction computed tomography angiography (CTA) for diagnosing intracranial aneurysms. A systematic literature search up to January 1, 2013 was performed in PubMed. Two independent reviewers selected 8 studies that compared subtraction CTA with digital...

journal_title：Experimental and therapeutic medicine

authors： Feng TY,Han XF,Lang R,Wang F,Wu Q

更新日期：2016-05-01 00:00:00

abstract：:Curcuma longa is a plant that belongs to the ginger family, Zingiberaceae. It has been used in Siddha medicine for thousands of years in Asia. Parkinson's disease (PD) is a degenerative disorder of the central nervous system that affects the motor system of the brain. Death of dopamine-producing cells in the substanti...

journal_title：Experimental and therapeutic medicine

authors： Ma XW,Guo RY

更新日期：2017-05-01 00:00:00

abstract：:A standard systemic therapy for patients with human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer (ABC) is yet to be identified. Sorafenib has been developed for the treatment of solid tumors, including breast cancer, as an oral multikinase inhibitor with antiangiogenic and antiproliferativ...

journal_title：Experimental and therapeutic medicine

authors： Tan QX,Qin QH,Lian B,Yang WP,Wei CY

更新日期：2014-05-01 00:00:00

abstract：:MicroRNAs (miRs), a class of small non-coding RNAs, function as key regulators in gene expression through binding to the 3'-untranslated region (UTR) of their target mRNA, which further leads to translational repression or mRNA degradation. Recently, miR-138 has been found to have a tumor suppressive role in a variety...

journal_title：Experimental and therapeutic medicine

authors： Yuan Z,Mo H,Mo L,He J,Wu Z,Lin X

更新日期：2017-06-01 00:00:00