Abstract:
INTRODUCTION:Squamous cell carcinoma is the most common neoplasm of the larynx, and its evolution depends on tumor staging. Vascular endothelial growth factor is a marker of angiogenesis, and its expression may be related to increased tumor aggressiveness, as evidenced by the presence of cervical lymphatic metastases. OBJECTIVES:To evaluate the expression of the vascular endothelial growth factor marker in non-glottic advanced squamous cell carcinoma of the larynx (T3/T4) and correlate it with the presence of cervical lymph node metastases. METHODS:Retrospective clinical study and immunohistochemical analysis of vascular endothelial growth factor through the German scale of immunoreactivity in products of non-glottic squamous cell carcinomas. RESULTS:This study analyzed 15 cases of advanced non-glottic laryngeal tumors (T3/T4), four of which exhibited cervical lymphatic metastases. There was no correlation between vascular endothelial growth factor expression and the presence of cervical metastases. CONCLUSION:Although vascular endothelial growth factor was expressed in a few cases, there was no correlation with the spread of cervical lymph metastases.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Bonhin RG,Rocha VB,Carvalho GM,Guimarães AC,Crespo AN,Chone CT,Amstalden EMdoi
10.1016/j.bjorl.2014.08.016subject
Has Abstractpub_date
2015-01-01 00:00:00pages
58-62issue
1eissn
1808-8694issn
1808-8686pii
S1808-8694(14)00148-7journal_volume
81pub_type
杂志文章abstract:INTRODUCTION:Perceptual evaluation is considered the gold standard to evaluate speech nasality. Several procedures are used to collect and analyze perceptual data, which makes it susceptible to errors. Therefore, there has been an increasing desire to find methods that can improve the assessment. OBJECTIVE:To describe...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:The use of the bilateral cochlear implants can promote the symmetrical development of the central auditory pathways, thus benefiting the development of auditory abilities and improving sound localization and the ability of auditory speech perception in situations of competitive noise. OBJECTIVE:To evaluat...
journal_title:Brazilian journal of otorhinolaryngology
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更新日期:2019-01-01 00:00:00
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doi:10.1016/s1808-8694(15)30570-x
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abstract:UNLABELLED:The hormonal changes that occur in a short time span promote modifications all over the woman's body, with physical and emotional manifestations which are frequently observed. AIM:to evaluate the activity of the external ciliated cells in women during their menstrual cycle, observing the effect of hormonal ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30759-x
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Auditory steady-state responses (ASSR) are an important tool to detect objectively frequency-specific hearing thresholds. Pure-tone audiometry is the gold-standard for hearing evaluation, although sometimes it may be inconclusive, especially in children and uncooperative adults. AIM:Compare pure tone thre...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.5935/1808-8694.20140009
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Newborn hearing screening (NHS) programs are implemented across the globe to detect early hearing impairment. In order to meet this objective, the quality of these programs should be monitored using internationally recognized indicators. OBJECTIVE:To evaluate a newborn hearing screening service (NHSS) usi...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2014.08.008
更新日期:2015-05-01 00:00:00
abstract::Fanconi's anemia is a rare autosomal recessive disorder characterized by congenital malformation, bone marrow failure and genomic instability, with a predisposition to develop malignancies, especially the leukemias and upper aerodigestive tract tumors. Due to inherent characteristics to this syndrome, the treatment of...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
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更新日期:2006-11-01 00:00:00
abstract:UNLABELLED:Among the methods for assessing swallowing sounds - videofluoroscopy modified barium study, fiberoptic swallowing endoscopy, neck auscultation through a microphone, accelerometer and, more recently, the Doppler sonar - we have chosen the latter. AIM:to analyze swallowing sounds by cervical auscultation usin...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract:INTRODUCTION:An ongoing discussion is found in medical literature about the reasons for changes in thyroid carcinoma incidence patterns over the last decades. OBJECTIVE:To analyze the clinical and pathological characteristics of thyroid carcinoma cases over a decade. METHODS:Cross-sectional study over an historical c...
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pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
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更新日期:2008-09-01 00:00:00
abstract:INTRODUCTION:Dysphonia is the main symptom of the disorders of oral communication. However, voice disorders also present with other symptoms such as difficulty in maintaining the voice (asthenia), vocal fatigue, variation in habitual vocal fundamental frequency, hoarseness, lack of vocal volume and projection, loss of ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.bjorl.2014.03.003
更新日期:2015-03-01 00:00:00
abstract:AIM:The objective of the present study was to analyze the microbiology of peritonsillar abscesses. METHODS:Thirty patients, mean age 24,2 years, with peritonsillar abscesses underwent aspiration of at least 3 mL of pus, which was cultured for aerobes and anaerobes. RESULTS:87% samples showed positive cultures. Aerobi...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30063-x
更新日期:2006-03-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2018.03.006
更新日期:2019-01-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
abstract:UNLABELLED:Upper respiratory tract infections are the most common causes of medical visits in children and adults, demanding massive use of antibiotics. Bacterial resistance caused by beta-lactamase is one of the most serious problems in this matter. Sultamicillin, a double pro-drug of Ampicillin/Sulbactan, is a potent...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/s1808-8694(15)30041-0
更新日期:2006-01-01 00:00:00
abstract:UNLABELLED:In classic rhytidectomy, there is little improvement in the center portion of the face. Aesthetic correction of malar prominence ptosis, accentuated nasolabial line, and jawl line, in most of the cases, require different approaches, such as the subperiosteal facelift. AIM:to show the cases and to evaluate t...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31014-4
更新日期:2006-09-01 00:00:00
abstract:INTRODUCTION:Methicillin-resistant staphylococcus aureus is an emerging problem for the treatment of chronic suppurative otitis media, and also for pediatric tympanostomy tube otorrhea. To date, there are no effective topical antibiotic drugs to treat methicillin-resistant staphylococcus aureus otorrhea. OBJECTIVE:In ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.05.002
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Promising treatments for tympanic membrane perforation closure have been studied. Therapies derived from tissue engineering probably eliminate the need for conventional surgery. Bacterial cellulose is presented as an alternative that is safe, biocompatible, and has low toxicity. OBJECTIVES:To investigate ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,随机对照试验
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更新日期:2016-03-01 00:00:00
abstract:INTRODUCTION:Studies that assess the upper airways in sleep-related breathing disorders have been performed only in patients with obstructive sleep apnea syndrome who seek medical attention. Therefore, in addition to the need for population studies, there are no data on the orofacial-cervical physical examination in su...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.05.015
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:Stuttering is a speech fluency disorder, and may be associated with neuroaudiological factors linked to central auditory processing, including changes in auditory processing skills and temporal resolution. OBJECTIVE:To characterize the temporal processing and long-latency auditory evoked potential in stut...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2016.02.015
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face. OBJECTIVE:To evaluate the prevalence of depressive symptoms in children and adolescents with nonsyndromic cleft lip and/or palate (nsCL/P). METHODS:We conducted an observational, case-control study, with a case stu...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.01.004
更新日期:2015-03-01 00:00:00
abstract:UNLABELLED:Choanal atresia is a rare disease and the incidence is 1: 5000-8000 newborns alive. It is more comom among female and usually is associated with others malformations. STUDY DESIGN:clinical retrospective. When unilateral its diagnose may be postpone because its symptoms are less life threating. But when bila...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31240-4
更新日期:2005-11-01 00:00:00
abstract:UNLABELLED:Benign Paroxysmal Positional Vertigo (BPPV) is one of the most common causes of dizziness; it constitutes the most common vestibular disorder in the elderly with vertigo. Its characteristic clinical aspect is dizziness at head movement, with not hearing alteration. AIM:This paper aims at studying the audiol...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30794-1
更新日期:2009-03-01 00:00:00
abstract:INTRODUCTION:Supratracheal laryngectomy has been described as a surgical procedure for glottic or supraglottic cancer extending to the subglottic region and/or involving the cricoarytenoid joint, aiming to preserve laryngeal function (breathing, phonation and swallowing), without diminishing locoregional cancer control...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2019.04.004
更新日期:2020-01-01 00:00:00
abstract:UNLABELLED:Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The disease more frequently affects the nasal mucosa and can occur independently of its clinical form or even before lesions on the skin or on other parts of the body. It is necessary to employ epidemiological surveillance of household c...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract:UNLABELLED:Tympanoplasty is done to eradicate ear pathology and to restore the conductive hearing mechanism (eardrum and ossicles). Some patients, however, do not tolerate tinnitus and question physicians about the results of surgery when tinnitus persists. AIM:to evaluate the progression of tinnitus in patients with ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30083-5
更新日期:2007-05-01 00:00:00
abstract:INTRODUCTION:Mutations in the otoferlin gene are responsible for auditory neuropathy. OBJECTIVE:To investigate the prevalence of mutations in the mutations in the otoferlin gene in patients with and without auditory neuropathy. METHODS:This original cross-sectional case study evaluated 16 index cases with auditory ne...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.03.005
更新日期:2015-05-01 00:00:00
abstract:UNLABELLED:High-frequency audiometry can detect early changes in auditory sensitivity resulting from processes such as aging. Nonetheless its use is still limited, and additional studies are required to establish its use, particularly among older adults. AIM:To compare pure tone thresholds for frequencies from 250 Hz ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31024-7
更新日期:2006-09-01 00:00:00
abstract:INTRODUCTION:Educators dealing with 0-6 years old children must be individuals who are willing to take all kind of measures in order to ensure the safety of children in educational institutions and playgrounds, providing protection from diseases, and who are able to apply first aid measures in case of an accident. OBJ...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2015.06.005
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:Knowledge of the different imaging tests and their appropriate indications is crucial to establish the diagnosis of temporomandibular disorders, especially in patients with overlapping signs and symptoms. OBJECTIVE:To present and assess the main diagnostic imaging tests for temporomandibular disorders and...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.bjorl.2015.06.010
更新日期:2016-05-01 00:00:00