Abstract：
INTRODUCTION:Promising treatments for tympanic membrane perforation closure have been studied. Therapies derived from tissue engineering probably eliminate the need for conventional surgery. Bacterial cellulose is presented as an alternative that is safe, biocompatible, and has low toxicity. OBJECTIVES:To investigate the effect on healing of direct application of a bacterial cellulose graft on the tympanic membrane compared to the conventional approach with autologous fascia. METHODS:Randomized controlled trial. Forty patients with tympanic membrane perforations secondary to chronic otitis media were included, and were randomly assigned to an experimental group (20), treated with a bacterial cellulose graft (BC) and control group (20), treated with autologous temporal fascia (fascia). We evaluated the surgical time, hospital stay, time of epithelialization and the rate of tympanic perforation closure. Hospital costs were compared. The statistical significance level accepted was established at p<0.05. RESULTS:The closure of perforations was similar in both groups. The average operation time in the fascia group was 76.50 min versus 14.06 min bacterial cellulose in the group (p=0.0001). The hospital cost by the Brazilian public health system was R$ 600.00 for the bacterial cellulose group, and R$ 7778.00 for the fascia group (p=0.0001). CONCLUSION:Bacterial cellulose grafts promoted the closure of the tympanic membrane perforations, and were demonstrated to be innovative, effective, safe, minimally invasive, efficacious and to have a very low cost.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Silveira FC,Pinto FC,Caldas Neto Sda S,Leal Mde C,Cesário J,Aguiar JLdoi
10.1016/j.bjorl.2015.03.015subject
Has Abstractpub_date
2016-03-01 00:00:00pages
203-8issue
2eissn
1808-8694issn
1808-8686pii
S1808-8694(15)00136-6journal_volume
82pub_type
杂志文章,随机对照试验abstract：INTRODUCTION:Several surgical techniques have been used during tonsillectomy to reduce complications. OBJECTIVES:To assess the effects of pillar suture in conjunction with tonsillectomy as compared to tonsillectomy without suture in children. METHODS:Two authors independently searched five databases (PubMed, SCOPUS, ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2019.12.007
更新日期：2020-01-25 00:00:00
abstract：UNLABELLED:Benign Paroxysmal Positional Vertigo (BPPV) is one of the most common causes of dizziness; it constitutes the most common vestibular disorder in the elderly with vertigo. Its characteristic clinical aspect is dizziness at head movement, with not hearing alteration. AIM:This paper aims at studying the audiol...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30794-1
更新日期：2009-03-01 00:00:00
abstract：UNLABELLED:Choanal atresia is a rare disease and the incidence is 1: 5000-8000 newborns alive. It is more comom among female and usually is associated with others malformations. STUDY DESIGN:clinical retrospective. When unilateral its diagnose may be postpone because its symptoms are less life threating. But when bila...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)31240-4
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abstract：INTRODUCTION:Studies that assess the upper airways in sleep-related breathing disorders have been performed only in patients with obstructive sleep apnea syndrome who seek medical attention. Therefore, in addition to the need for population studies, there are no data on the orofacial-cervical physical examination in su...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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abstract：UNLABELLED:Epistaxis is the main otorhinolaryngology emergency and, in severe cases, it can lead to hemodynamic instability and be life threatening. AIM:To evaluate factors involved in epistaxis resistant to nasal packing that needed surgical treatment, as well as post-surgical results. MATERIAL AND METHODS:Retrospec...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：INTRODUCTION:Warthin tumors are the second most common benign tumors of the parotid gland. We examined the clinical features of Warthin tumors in our hospital, and analyzed the consistency within the literatures. OBJECTIVE:The aim of this study is to analyze the clinical features of Warthin tumors in our 10-year exper...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
abstract：UNLABELLED:Upper respiratory tract infections are the most common causes of medical visits in children and adults, demanding massive use of antibiotics. Bacterial resistance caused by beta-lactamase is one of the most serious problems in this matter. Sultamicillin, a double pro-drug of Ampicillin/Sulbactan, is a potent...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2006-01-01 00:00:00
abstract：INTRODUCTION:Vocal fold polyp is a benign proliferative disease in the superficial lamina propria of the vocal fold, and vocal microsurgery can improve the voice quality of patients with vocal fold polyp. In preliminary studies, we found that vocal training could improve the vocal quality of patients with early vocal f...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2018.03.014
更新日期：2019-01-01 00:00:00
abstract：UNLABELLED:The present study aimed at reporting on the characteristics, prognostic factors and treatment outcomes of 18 cases of nasosinusal mucosa melanoma, and do a literature review on the subject. METHODS:between 1995 and 2005, 18 patients consecutively diagnosed with nasosinusal mucosa melanoma were managed in ou...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1590/s1808-86942011000100010
更新日期：2011-01-01 00:00:00
abstract：INTRODUCTION:Ototoxicity refers to cellular damage or function impairment developing in the inner ear in association with any therapeutic agent or chemical substance, and still represents the principal side-effect restricting the use of cisplatin. OBJECTIVE:The aim of this study was to perform a biochemical, functiona...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
abstract：UNLABELLED:Frontonasal dysplasia (FND) is a rare malformative complex affecting the frontal portion of the face, the eyes and the nose; it may occur singly or associated with other clinical signs. No systematic studies describing hearing in this condition were found. AIM:To evaluate hearing sensitivity and sound stimu...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Amyloidosis is the term applied to a diverse group of disorders that share the features of deposition of amorphous, extracellular material at various sites. Amyloid deposits may occur locally or may involve various organs, resulting number of clinical manifestations. Amyloidosis of the head and neck is rare ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type：
doi：10.1016/j.bjorl.2020.11.011
更新日期：2020-12-19 00:00:00
abstract：UNLABELLED:Exposure to ototoxic chemical products in the presence or absence of noise can cause irreversible injury to the hearing of workers for a significantly short period of exposure period. AIM:to perform a comparative study, through audiometric tests, in workers exposed to noise only and noise associated with ch...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:In different parts of the world, mutations in the GJB2 gene are associated with nonsyndromic hearing loss, and the homozygous 35delG mutation (p.Gly12Valfs*2) is a major cause of hereditary hearing loss. However, the 35delG mutation is not equally prevalent across ethnicities, making it important to study ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：INTRODUCTION:Allergic rhinitis is a chronic inflammatory disease which affects 1 out of 6 individuals. Perennial allergic rhinitis accounts for 40% of AR cases. Ciclesonide is one of the relatively new intranasal steroid for allergic rhinitis. OBJECTIVE:The purpose of this study was to evaluate the efficacy and safety...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,meta分析
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更新日期：2019-01-01 00:00:00
abstract：INTRODUCTION:Vascular endothelial growth factor is thought to be an important angiogenic factor involved in tumor growth, progression, and metastasis. OBJECTIVE:The present study evaluated the relation between tissue expression, serum and salivary levels of vascular endothelial growth factor in head and neck squamous ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.03.001
更新日期：2014-11-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2014-05-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2015-05-01 00:00:00
abstract：INTRODUCTION:The extent of epithelial lesion in allergic and non-allergic rhinitis and its association with inflammatory changes in nasal lavage has not been clarified. OBJECTIVE:To verify the association between the inflammatory cells in the nasal lavage, epithelial lesion extent and basement membrane thickness, in t...
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pub_type： 杂志文章
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更新日期：2020-01-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2008-01-01 00:00:00
abstract：:Squamous papillomas are benign neoplasms. The occurrence of middle ear squamous papilloma is rare. It is usually associated with nasosinusal pathology. The authors report a case of middle ear squamous papilloma and discuss its diagnostic aspects. ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2005-05-01 00:00:00
abstract：INTRODUCTION:Knowledge of the characteristics related to profound hearing loss is a matter of great importance, as it allows for the etiological and prognostic identification and strategic planning for public health interventions. OBJECTIVE:To assess the different etiologies of hearing loss, age at diagnosis of the he...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.05.011
更新日期：2014-07-01 00:00:00
abstract：UNLABELLED:The immunodeficiency state in HIV infected patients has been the cause of severe episodes of Recurrent Aphthous Stomatitis (RAS). AIM:Our study aims to establish correlation between the manifestations of RAS and the immunosuppression state caused by HIV infection, through counting of CD4+ cells, CD8+ cells,...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2005-07-01 00:00:00
abstract：INTRODUCTION:Leiomyosarcoma is a tumor which is rarely seen in the thyroid gland. The diagnosis may be difficult and the treatment is controversial. OBJECTIVE:The objective of the study is to review the literature about a rare malignant disease of the thyroid gland which has high mortality. METHODS:Two cases of thyro...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
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更新日期：2016-01-01 00:00:00
abstract：UNLABELLED:The ideal approach for the treatment of glottal insufficiency remains a challenge for laryngologists. AIM:This experimental study assessed the histological changes and fibrosis caused by autologous fascia lata grafts into the rabbit voice muscle. STUDY DESIGN:A clinical and experimental study. METHODS:A 0...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2011-03-01 00:00:00
abstract：UNLABELLED:Children with language or learning impairment and normal hearing need phoniatric assessment to analyse various communication and development aspects targeting the differential diagnosis and therapeutic indications. OBJECTIVE:Characterize clinical and epidemiological features of a pediatric population treate...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2013-03-01 00:00:00
abstract：INTRODUCTION:In ideal listening situations, subjects with normal hearing can easily understand speech, as can many subjects who have a hearing loss. OBJECTIVE:To present the validation of the Word Recognition Test in a Free Field in the Presence of Noise in normal-hearing adults. METHODS:Sample consisted of 100 healt...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2017-01-01 00:00:00
abstract：UNLABELLED:Saccades are part of the electrooculography tests battery. The cerebellum has important connections with the brainstem and thalamic structures involved in the generation of saccades. AIM:to study saccadic movements in subjects with cerebellar disorders. STUDY METHOD:Prospective clinical study. MATERIALS A...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：UNLABELLED:The vibration of the vocal fold lamina propria is an important factor involved in vocal production and aging may change the amount of hyaluronic acid in the vocal fold leading to dysphonia. AIMS:This study compares the concentration of hyaluronic acid in vocal folds of aged and young female rats. STUDY DES...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2012-06-01 00:00:00
