Management of Osteoarthritis with Avocado/Soybean Unsaponifiables.

abstract：:Objective To identify if the time of day and pre-imaging exercise matter while performing T2* mapping of hip joint cartilage at 3 T. Design Nine asymptomatic healthy volunteers (mean age 27.4 ± 4.0 years) with no obvious morphological evidence of cartilage damage were enrolled. The MRI protocol included a double-echo ...

journal_title：Cartilage

authors： Hesper T,Hosalkar HS,Schleich C,Antoch G,Welsch GH,Krauspe R,Zilkens C,Bittersohl B

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Describe the local morphological response of the articular-epiphyseal cartilage complex to surgical stab incision in the distal femur of foals, with emphasis on the relationship between growth cartilage injury, enchondral ossification, and repair. DESIGN:Nine foals were induced into general anesthesia at the...

journal_title：Cartilage

authors： Olstad K,Hendrickson EH,Ekman S,Carlson CS,Dolvik NI

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:We sought to determine whether rates of postoperative arthrofibrosis following tibial tuberosity osteotomy (TTO) with complete mobilization of the fragment (TTO-HD) are comparable to TTOs where the hinge remained intact (TTO-HI). DESIGN:Patients who underwent TTO with concomitant cartilage repair procedure b...

journal_title：Cartilage

authors： Merkely G,Ackermann J,Sheehy E,Gomoll AH

更新日期：2020-10-23 00:00:00

abstract：OBJECTIVE:TNIIIA2 is a peptide of the extracellular matrix glycoprotein tenascin-C. We evaluated whether intra-articular injection of TNIIIA2 could prevent articular cartilage degeneration without inducing synovitis in an osteoarthritis mice model. DESIGN:Ten micrograms per milliliter of TNIIIA2 were injected into the...

journal_title：Cartilage

authors： Hattori T,Hasegawa M,Unno H,Iino T,Fukai F,Yoshida T,Sudo A

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:Focal cartilage lesions in the knee joint have limited capacity to heal. Current animal experiments show that incisions of the deep zone of a cartilage allograft allow acceptable integration for the graft. QUESTIONS/PURPOSES:We performed this clinical study to determine (1) if the multiply incised cartilage...

journal_title：Cartilage

authors： Bardos T,Vancsodi J,Farkas B,Fazekas A,Nagy SA,Bogner P,Vermes C,Than P

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To evaluate clinical, functional, and radiographic outcomes of patients who underwent bipolar osteochondral allograft transplantation (OCAT) of the patellofemoral joint (PFJ). DESIGN:Prospectively collected data on 18 knees who underwent fresh osteochondral allograft transplantation of the patella and trochl...

journal_title：Cartilage

authors： Mirzayan R,Charles MD,Batech M,Suh BD,DeWitt D

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Full-depth cartilage lesions do not heal and the long-term clinical outcome is uncertain. In the symptomatic middle-aged (35-60 years) patient, treatment with metal implants has been proposed. However, the cartilage health surrounding these implants has not been thoroughly studied. Our objective was to evalu...

journal_title：Cartilage

authors： Martinez-Carranza N,Hultenby K,Lagerstedt AS,Schupbach P,Berg HE

更新日期：2019-01-01 00:00:00

abstract：:Objective To measure and identify the determinants of the outcomes after hip/knee arthroplasty (HA/KA) in patients with osteoarthritis during the first postsurgical year. Design In this prospective observational study, we evaluated the preoperative and postoperative (3, 6, and 12 months) outcomes of 626 patients who u...

journal_title：Cartilage

authors： Neuprez A,Neuprez AH,Kaux JF,Kurth W,Daniel C,Thirion T,Huskin JP,Gillet P,Bruyère O,Reginster JY

更新日期：2018-04-01 00:00:00

abstract：:The objective of this study was to characterize magnetic resonance imaging (MRI) findings and correlate with clinical results in patients who underwent autologous chondrocyte implantation (ACI) of osteochondral lesions of the talus (OLT). METHODS:Twenty-four grafts were evaluated at a mean 65.8 months after ACI for O...

journal_title：Cartilage

authors： Chan KW,Ferkel RD,Kern B,Chan SS,Applegate GR

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of accelerated compared with traditional postoperative weightbearing (WB) rehabilitation following matrix-induced autologous chondrocyte implantation (MACI) of the knee, using MRI. METHODS:A randomized controlled study design was used to assess MRI-based outcomes of MACI gra...

journal_title：Cartilage

authors： Ebert JR,Fallon M,Robertson WB,Lloyd DG,Zheng MH,Wood DJ,Ackland T

更新日期：2011-01-01 00:00:00

abstract：:Objective To evaluate the outcome of patients who have undergone simultaneous osteotomy and osteochondral allograft (OCA) transplantation. Our hypothesis is that use of high tibial osteotomy and fresh OCA in a combined procedure is safe and effective without increasing morbidity in comparison to OCA alone. Design A ca...

journal_title：Cartilage

authors： Hsu AC,Tirico LEP,Lin AG,Pulido PA,Bugbee WD

更新日期：2018-07-01 00:00:00

abstract：:Objective This study is a literature review from 2010 to 2014 concerning the quality of evidence in clinical trials about microfracture in attempt to repair articular cartilage. We have decided to focus on microfracturing, since this seems to be the best documented technique. Interest in evaluation of publication qual...

journal_title：Cartilage

authors： Frehner F,Benthien JP

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To assess the continued effectiveness and safety of Gel-200 following observation and open-label retreatment in an extension protocol following a randomized, double-blind, phosphate buffered saline (PBS)-controlled trial (initial treatment trial). DESIGN:Patients who completed initial blinded treatment were ...

journal_title：Cartilage

authors： Strand V,Baraf HS,Lavin PT,Lim S,Hosokawa H

更新日期：2012-10-01 00:00:00

abstract：:Nucleofection of chondrocytes has been shown to be an adequate method of transfection. Using Amaxa's nucleofection system, transfection efficiencies up to 89% were achievable for vector (pmaxGFP) and 98% for siRNA (siGLO) into passaged chondrocytes. However, such methods rely on costly commercial kits with proprietary...

journal_title：Cartilage

authors： Parreno J,Delve E,Andrejevic K,Paez-Parent S,Wu PH,Kandel R

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Delamination of the chondral surface of an osteochondral allograft (OCA) from the underlying cancellous bone has been described as a mode of failure after implantation in the knee. Our hypothesis was that increased storage time of the OCA is associated with increased risk of graft delamination after implan...

journal_title：Cartilage

authors： Rauck RC,Wang D,Tao M,Williams RJ

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:There are limited data on bone dimension and cartilage thickness of the distal humeral articular surface. This study aimed to evaluate sex- and age-related bone dimension and cartilage thickness differences and assess the effect of cartilage thickness on distal humeral shape. DESIGN:Elbow magnetic resonance ...

journal_title：Cartilage

authors： Misir A,Gunay AE,Oguzkaya S,Uzun E,Kizkapan TB,Yildiz KI,Ozcamdalli M

更新日期：2020-02-10 00:00:00

abstract：:Articular cartilage injuries of the knee and ankle are common, and a number of different methods have been developed in an attempt to improve their repair. Clinically, there are 2 distinct aims of cartilage repair: 1) restoration of joint function and 2) prevention or at least delay of the onset of osteoarthritis. The...

journal_title：Cartilage

authors： McIlwraith CW,Fortier LA,Frisbie DD,Nixon AJ

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To compare the progression of biochemical biomarkers of osteoarthritis (OA), knee pain, and function between nonobese patients (NON), obese patients without depression (OBESE), and obese patients with comorbid depression (O + D). DESIGN:Utilizing the FNIH OA Biomarkers Consortium dataset, we categorized knee...

journal_title：Cartilage

authors： Jacobs CA,Vranceanu AM,Thompson KL,Lattermann C

更新日期：2020-01-01 00:00:00

abstract：:Introduction Autologous osteochondral transplantation (AOT) is a treatment for osteochondral lesions with known concerns, including histological degradation of the graft and poor cartilage integration. Platelet-rich plasma (PRP) and hyaluronic acid (HA) have been described has having the potential to improve results. ...

journal_title：Cartilage

authors： Smyth NA,Ross KA,Haleem AM,Hannon CP,Murawski CD,Do HT,Kennedy JG

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:Ankle arthropathy is a frequent and invalidating manifestation of hemophilia. Arthrodesis is the gold standard surgical procedure in end-stage disease, with many drawbacks in young patients. Recent literature has shown increase interest in regenerative procedures in hemophilic arthropathy, which may be desira...

journal_title：Cartilage

authors： Buda R,Cavallo M,Castagnini F,Cenacchi A,Natali S,Vannini F,Giannini S

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this systematic review and meta-analysis was to evaluate the effect of electromagnetic field treatment on the symptoms of knee osteoarthritis (OA). In addition, the influence of the type of control group and other covariates have been investigated to identify the sources of heterogeneity in the...

journal_title：Cartilage

authors： Viganò M,Perucca Orfei C,Ragni E,Colombini A,de Girolamo L

更新日期：2020-06-08 00:00:00

abstract：OBJECTIVE:Articular cartilage is incapable of effective repair following injury or during osteoarthritis. While there have been developments in cartilage repair technologies, there is a need to advance biologically relevant models for preclinical testing of biomaterial and regenerative therapies. This study describes c...

journal_title：Cartilage

authors： Styczynska-Soczka K,Amin AK,Simpson AHW,Hall AC

更新日期：2020-06-21 00:00:00

abstract：OBJECTIVE:Osteoarthritis (OA) is an incurable joint disease characterized by pronounced pain. MicroRNAs constitute epigenetic mechanisms that may affect OA progression by contributing to changes in chondrocyte phenotype. This study investigates for the first time whether there is a link between miRNA-1 (miR-1) and OA p...

journal_title：Cartilage

authors： Yang Y,Wang Y,Jia H,Li B,Xing D,Li JJ

更新日期：2020-11-20 00:00:00

abstract：OBJECTIVE:Osteoarthritis is a painful, chronic joint disease affecting man and animals with no known curative therapies. Palliative nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used but they cause adverse side effects prompting the search for safer alternatives. To address this need, we evaluated the anti...

journal_title：Cartilage

authors： Grzanna MW,Secor EJ,Fortuno LV,Au AY,Frondoza CG

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The identification of early-stage osteoarthritis (OA) is crucial for the deceleration of its progression; however, no reliable biomarker is available for this purpose. The current study aimed to determine the role of serum calprotectin in the detection of early-stage knee OA. DESIGN:In a case-control study, ...

journal_title：Cartilage

authors： Safa A,Bagherifard A,Hadi Al-Baseesee H,Amini Kadijani A,Yahyazadeh H,Azizi M,Akbari A,Mirzaei A

更新日期：2020-10-01 00:00:00

abstract：:Joint injuries are very common in the athletic population, especially professional soccer players, with an incidence of 10 to 35.5 injuries per 1000 hours. Most soccer-related joint injuries occur in the lower extremities, with 16% to 46% occurring in the knee and 17% to 40% occurring in the ankle. Because of the limi...

journal_title：Cartilage

authors： Lee HH,Chu CR

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of intra-articular injection of autologous micronized adipose tissue (MAT) with ankle arthroscopic debridement in patients with advanced-stage posttraumatic osteoarthritis (PTOA) of ankle. DESIGN:A retrospective cohort study investigating patients treated with arthroscopic debridement ...

journal_title：Cartilage

authors： Shimozono Y,Dankert JF,Kennedy JG

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Osteochondral allograft (OCA) transplantation is an increasingly common treatment for patients with symptomatic focal chondral lesions of the knee. There has been increasing interest in determining predictive factors to maximize patient benefit after this operation. The aim of the present study is to evaluat...

journal_title：Cartilage

authors： Owusu-Akyaw KA,Bido J,Warner T,Rodeo SA,Williams RJ

更新日期：2020-09-17 00:00:00

abstract：:Various systematic reviews have recently shown that intra-articular platelet-rich plasma (IA-PRP) can lead to symptomatic relief of knee osteoarthritis for up to 12 months. There exist limited data on its use in small joints, such as the trapeziometacarpal joint (TMJ) or carpometacarpal joint (CMCJ) of the thumb. A pr...

journal_title：Cartilage

authors： Malahias MA,Roumeliotis L,Nikolaou VS,Chronopoulos E,Sourlas I,Babis GC

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To assess the clinical outcome of patients treated with autologous chondrocyte implantation using ChondroCelect in daily practice. METHODS:The study is a cross-sectional analysis of an open-label, noninterventional cohort. The setting was a compassionate use program, involving 43 orthopaedic centers in 7 Eur...

journal_title：Cartilage

authors： Vanlauwe J,Huylebroek J,Van Der Bauwhede J,Saris D,Veeckman G,Bobic V,Victor J,Almqvist KF,Verdonk P,Fortems Y,Van Lommel N,Haazen L

更新日期：2012-04-01 00:00:00