Does Flipping the Tubercle for Improved Cartilage Repair Exposure Increase the Risk for Arthrofibrosis?

abstract：OBJECTIVE:Accurate arthroscopic evaluation of cartilage lesions could significantly improve the outcome of repair surgery. In this study, we investigated for the first time the potential of intra-articular ultrasound as an arthroscopic tool for grading cartilage defects in the human shoulder joint in vivo and compared ...

journal_title：Cartilage

authors： Puhakka J,Afara IO,Paatela T,Sormaala MJ,Timonen MA,Virén T,Jurvelin JS,Töyräs J,Kiviranta I

更新日期：2016-07-01 00:00:00

abstract：:This study addressed difficulties in evaluating osteoarthritis (OA) progression in species with thin cartilage. Feasibility of using short, nonequilibrium contrast-enhanced micro-computed tomography (CE-μCT) to evaluate the physical and biochemical properties of cartilage was investigated. A preliminary in vitro study...

journal_title：Cartilage

authors： Flynn C,Hurtig M,Linden AZ

更新日期：2020-05-26 00:00:00

abstract：OBJECTIVE:A systematic review and meta-analysis of Autologous Matrix-Induced Chondrogenesis (AMIC®) outcomes for grade III/IV chondral and osteochondral lesions of the knee treated with Chondro-Gide®. DESIGN:Studies with a minimum follow-up of 1 year providing clinical results of AMIC repair in the knee were included ...

journal_title：Cartilage

authors： Steinwachs MR,Gille J,Volz M,Anders S,Jakob R,De Girolamo L,Volpi P,Schiavone-Panni A,Scheffler S,Reiss E,Wittmann U

更新日期：2019-09-11 00:00:00

abstract：BACKGROUND:Osteochondral allograft (OCA) transplantation is an increasingly common treatment for patients with symptomatic focal chondral lesions of the knee. There has been increasing interest in determining predictive factors to maximize patient benefit after this operation. The aim of the present study is to evaluat...

journal_title：Cartilage

authors： Owusu-Akyaw KA,Bido J,Warner T,Rodeo SA,Williams RJ

更新日期：2020-09-17 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of accelerated compared with traditional postoperative weightbearing (WB) rehabilitation following matrix-induced autologous chondrocyte implantation (MACI) of the knee, using MRI. METHODS:A randomized controlled study design was used to assess MRI-based outcomes of MACI gra...

journal_title：Cartilage

authors： Ebert JR,Fallon M,Robertson WB,Lloyd DG,Zheng MH,Wood DJ,Ackland T

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Ankle arthropathy is a frequent and invalidating manifestation of hemophilia. Arthrodesis is the gold standard surgical procedure in end-stage disease, with many drawbacks in young patients. Recent literature has shown increase interest in regenerative procedures in hemophilic arthropathy, which may be desira...

journal_title：Cartilage

authors： Buda R,Cavallo M,Castagnini F,Cenacchi A,Natali S,Vannini F,Giannini S

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:Hyaluronic acid-transglutaminase (HA-TG) is an enzymatically crosslinkable adhesive hydrogel with chondrogenic properties demonstrated in vitro and in an ectopic mouse model. In this study, we investigated the feasibility of using HA-TG in a collagen scaffold to treat chondral lesions in an ovine model, to ev...

journal_title：Cartilage

authors： Levinson C,Cavalli E,von Rechenberg B,Zenobi-Wong M,Darwiche SE

更新日期：2021-01-29 00:00:00

abstract：OBJECTIVE:To determine the optimal environmental conditions for chondrogenic differentiation of human adipose tissue-derived mesenchymal stromal/stem cells (AMSCs). In this investigation we specifically investigate the role of oxygen tension and 3-dimensional (3D) culture systems. DESIGN:Both AMSCs and primary human c...

journal_title：Cartilage

authors： Galeano-Garces C,Camilleri ET,Riester SM,Dudakovic A,Larson DR,Qu W,Smith J,Dietz AB,Im HJ,Krych AJ,Larson AN,Karperien M,van Wijnen AJ

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this article is to report on a distinctive pattern of linear femoral head chondral lesions that were observed in 7 patients who underwent hip arthroscopy for the treatment of mixed-type femoroacetabular impingement (FAI). DESIGN:Between 2010 and 2012, 702 patients were treated with hip arthros...

journal_title：Cartilage

authors： Philippon MJ,Goljan P,Devitt BM,Peixoto LP

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Delamination of the chondral surface of an osteochondral allograft (OCA) from the underlying cancellous bone has been described as a mode of failure after implantation in the knee. Our hypothesis was that increased storage time of the OCA is associated with increased risk of graft delamination after implan...

journal_title：Cartilage

authors： Rauck RC,Wang D,Tao M,Williams RJ

更新日期：2019-10-01 00:00:00

abstract：:INTRODUCTION: The zone of calcified cartilage (ZCC) anchors articular cartilage (AC) to subchondral bone through a layer of intermediate stiffness. The regulation and functional consequences of cartilage calcification may vary with depth from the articular surface. The hypothesis of this study was that the in vitro ca...

journal_title：Cartilage

authors： Hwang J,Kyubwa EM,Bae WC,Bugbee WD,Masuda K,Sah RL

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to fully characterize the mechanics of an in vivo impactor and correlate the mechanics with superficial cracking of articular surfaces. DESIGN:A spring-loaded impactor was used to apply energy-controlled impacts to the articular surfaces of neonatal bovine cartilage. The simul...

journal_title：Cartilage

authors： Bonnevie ED,Delco ML,Fortier LA,Alexander PG,Tuan RS,Bonassar LJ

更新日期：2015-10-01 00:00:00

abstract：:Objective To test different fixation methods of a 3-dimensionally woven poly(ϵ-caprolactone) (PCL) scaffold within chondral defects of a weightbearing large animal model. Methods Full thickness chondral defects were made in the femoral condyles of 15 adult male Yucatan mini-pigs. Two surgical approaches were compared ...

journal_title：Cartilage

authors： Friedman JM,Sennett ML,Bonadio MB,Orji KO,Neuwirth AL,Keah N,Carey JL,Moutos FT,Estes BT,Guilak F,Madry H,Mauck RL,Dodge GR

更新日期：2018-10-01 00:00:00

abstract：:Nucleofection of chondrocytes has been shown to be an adequate method of transfection. Using Amaxa's nucleofection system, transfection efficiencies up to 89% were achievable for vector (pmaxGFP) and 98% for siRNA (siGLO) into passaged chondrocytes. However, such methods rely on costly commercial kits with proprietary...

journal_title：Cartilage

authors： Parreno J,Delve E,Andrejevic K,Paez-Parent S,Wu PH,Kandel R

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Recent studies have implicated the cyclin dependent kinase inhibitor, p21, in enhanced tissue regeneration observed in MRL/MpJ "super-healer" mice. Specifically, p21 is downregulated in MRL cells and similar ear hole closure to MRL mice has been observed in p21-/- mice. However, the direct implications of p21...

journal_title：Cartilage

authors： Jablonski CL,Besler BA,Ali J,Krawetz RJ

更新日期：2019-09-26 00:00:00

abstract：:Joint injuries are very common in the athletic population, especially professional soccer players, with an incidence of 10 to 35.5 injuries per 1000 hours. Most soccer-related joint injuries occur in the lower extremities, with 16% to 46% occurring in the knee and 17% to 40% occurring in the ankle. Because of the limi...

journal_title：Cartilage

authors： Lee HH,Chu CR

更新日期：2012-01-01 00:00:00

abstract：:Objective To measure and identify the determinants of the outcomes after hip/knee arthroplasty (HA/KA) in patients with osteoarthritis during the first postsurgical year. Design In this prospective observational study, we evaluated the preoperative and postoperative (3, 6, and 12 months) outcomes of 626 patients who u...

journal_title：Cartilage

authors： Neuprez A,Neuprez AH,Kaux JF,Kurth W,Daniel C,Thirion T,Huskin JP,Gillet P,Bruyère O,Reginster JY

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:We have recently shown that mesenchymal stem cells (MSCs) embedded in a hyaluronic acid (HA) hydrogel and exposed to chondrogenic factors (transforming growth factor-β3 [TGF-β3]) produce a cartilage-like tissue in vitro. The current objective was to determine if these same factors could be combined immediatel...

journal_title：Cartilage

authors： Fisher MB,Belkin NS,Milby AH,Henning EA,Söegaard N,Kim M,Pfeifer C,Saxena V,Dodge GR,Burdick JA,Schaer TP,Steinberg DR,Mauck RL

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to assess the effect of granulocyte colony-stimulating factor (G-CSF) on osteochondral defect repair in the rat knee. DESIGN:Twenty-six 12-week-old male Lewis rats were randomly divided into 2 groups. From day 0 to day 4, the G-CSF group received glycosylated G-CSF, and the co...

journal_title：Cartilage

authors： Okano T,Mera H,Itokazu M,Okabe T,Koike T,Nakamura H,Wakitani S

更新日期：2014-04-01 00:00:00

abstract：:The objective was to evaluate short-term outcomes of patients of more than 60 years old, who underwent arthroscopic treatment for femoroacetabular impingement (FAI). The study design was a nonrandomized controlled clinical trial; this was a prospective study in 15 patients (15 hips) over 60 years old. Inclusion criter...

journal_title：Cartilage

authors： Mardones RM,Nemtala F,Tomic A

更新日期：2010-07-01 00:00:00

abstract：:Articular cartilage injuries, and corresponding surgical procedures, are occurring with increasing frequency as identified by a review of recent surgical trends. Concerns have grown in recent years regarding the longevity of results following microfracture, with a shift toward cartilage restoration procedures in recen...

journal_title：Cartilage

authors： Degen RM,Tetreault D,Mahony GT,Williams RJ

更新日期：2016-10-01 00:00:00

abstract：:Articular cartilage injuries of the knee and ankle are common, and a number of different methods have been developed in an attempt to improve their repair. Clinically, there are 2 distinct aims of cartilage repair: 1) restoration of joint function and 2) prevention or at least delay of the onset of osteoarthritis. The...

journal_title：Cartilage

authors： McIlwraith CW,Fortier LA,Frisbie DD,Nixon AJ

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Treatments for steroid-induced osteonecrosis of the knee remains challenging, and there has not been sufficient evidence to support joint preservation surgery. This study evaluated long-term outcomes of osteochondral autologous transplantation (OAT) for steroid-induced osteonecrosis of the knee. DESIGN:This ...

journal_title：Cartilage

authors： Nishitani K,Nakagawa Y,Kobayashi M,Nakamura S,Mukai S,Kuriyama S,Matsuda S

更新日期：2020-09-10 00:00:00

abstract：OBJECTIVE:Bone morphogenetic protein 2 (BMP2) plays important roles in cartilage growth and development. Paradoxically, elevated levels of BMP2 leads to hypertrophic differentiation and osteoarthritis of cartilage. We examined the in vivo loss of BMP2 in cells expressing aggrecan of the mandibular condyle and knee. DE...

journal_title：Cartilage

authors： O'Brien MH,Dutra EH,Mehta S,Chen PJ,Yadav S

更新日期：2020-12-14 00:00:00

abstract：OBJECTIVE:Our aim is to explore the candidate pathogenesis genes and pathways of developmental dysplasia of hip (DDH). DESIGN:Proliferating primary chondrocytes from hip cartilage were used for total RNA extraction including 5 DDH patients and 5 neck of femur fracture (NOF) subjects. Genome-wide mRNA and microRNA (miR...

journal_title：Cartilage

authors： Cheng B,Jia Y,Wen Y,Hou W,Xu K,Liang C,Cheng S,Liu L,Chu X,Ye J,Yao Y,Zhang F,Xu P

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of intra-articular injection of autologous micronized adipose tissue (MAT) with ankle arthroscopic debridement in patients with advanced-stage posttraumatic osteoarthritis (PTOA) of ankle. DESIGN:A retrospective cohort study investigating patients treated with arthroscopic debridement ...

journal_title：Cartilage

authors： Shimozono Y,Dankert JF,Kennedy JG

更新日期：2020-08-06 00:00:00

abstract：OBJECTIVE:Excessive use of glucocorticoids (GCs) may cause adverse effects on the skeletal system in children. However, only a few studies have reported the effects of GCs on the epiphyseal cartilage. This study aimed to uncover the subsequent epiphyseal cartilage changes of immature femoral heads after excessive GC tr...

journal_title：Cartilage

authors： Jin S,Yang L,Meng C,He Y,Ma K,Huang W,Wang H

更新日期：2020-12-03 00:00:00

abstract：OBJECTIVE:Telomere length and telomerase activity are important indicators of cellular senescence and replicative ability. Loss of telomerase is associated with ageing and the development of osteoarthritis. Implantation of telomerase-positive cells, chondrocytes, or stem cells expressing a normal chondrocyte phenotype ...

journal_title：Cartilage

authors： Wilson B,Novakofski KD,Donocoff RS,Liang YX,Fortier LA

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To compare the progression of biochemical biomarkers of osteoarthritis (OA), knee pain, and function between nonobese patients (NON), obese patients without depression (OBESE), and obese patients with comorbid depression (O + D). DESIGN:Utilizing the FNIH OA Biomarkers Consortium dataset, we categorized knee...

journal_title：Cartilage

authors： Jacobs CA,Vranceanu AM,Thompson KL,Lattermann C

更新日期：2020-01-01 00:00:00

abstract：:Because of poor regenerative capabilities of cartilage, reconstruction of similar rigidity and flexibility is difficult, challenging, and restricted. The aim of the present investigation was to develop cost-effective acellular xenogeneic biomaterial as cartilage substitution. Two novel biometrics have been developed u...

journal_title：Cartilage

authors： Das P,Rajesh K,Lalzawmliana V,Bavya Devi K,Basak P,Lahiri D,Kundu B,Roy M,Nandi SK

更新日期：2019-06-19 00:00:00