Arthroscopic Treatment of Femoroacetabular Impingement in Patients over 60 Years Old: Preliminary Report of a Pilot Study.

abstract：OBJECTIVE:The objective of this study was to fully characterize the mechanics of an in vivo impactor and correlate the mechanics with superficial cracking of articular surfaces. DESIGN:A spring-loaded impactor was used to apply energy-controlled impacts to the articular surfaces of neonatal bovine cartilage. The simul...

journal_title：Cartilage

authors： Bonnevie ED,Delco ML,Fortier LA,Alexander PG,Tuan RS,Bonassar LJ

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:The low regenerative potential of cartilage contributed to the development of different cell therapies aimed to improve the clinical outcome in young patients with Osteochondral Lesions of the Talus (OLT). This study is designed to assess the regenerative potential of autologous matrix-induced Bone Marrow Asp...

journal_title：Cartilage

authors： Desando G,Bartolotti I,Vannini F,Cavallo C,Castagnini F,Buda R,Giannini S,Mosca M,Mariani E,Grigolo B

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:The current therapeutic strategy for posttraumatic osteoarthritis (PTOA) focuses on early intervention to attenuate disease progression, preserve joint function, and defer joint replacement timing. Sequential transcriptomic changes of articular cartilage in a rat model were investigated to explore the molecul...

journal_title：Cartilage

authors： Liu CC,Lee HC,Peng YS,Tseng AH,Wu JL,Tsai WY,Wong CS,Su LJ

更新日期：2019-05-20 00:00:00

abstract：OBJECTIVE:The objective of this study was to assess the effect of granulocyte colony-stimulating factor (G-CSF) on osteochondral defect repair in the rat knee. DESIGN:Twenty-six 12-week-old male Lewis rats were randomly divided into 2 groups. From day 0 to day 4, the G-CSF group received glycosylated G-CSF, and the co...

journal_title：Cartilage

authors： Okano T,Mera H,Itokazu M,Okabe T,Koike T,Nakamura H,Wakitani S

更新日期：2014-04-01 00:00:00

abstract：:INTRODUCTION: The zone of calcified cartilage (ZCC) anchors articular cartilage (AC) to subchondral bone through a layer of intermediate stiffness. The regulation and functional consequences of cartilage calcification may vary with depth from the articular surface. The hypothesis of this study was that the in vitro ca...

journal_title：Cartilage

authors： Hwang J,Kyubwa EM,Bae WC,Bugbee WD,Masuda K,Sah RL

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:TNIIIA2 is a peptide of the extracellular matrix glycoprotein tenascin-C. We evaluated whether intra-articular injection of TNIIIA2 could prevent articular cartilage degeneration without inducing synovitis in an osteoarthritis mice model. DESIGN:Ten micrograms per milliliter of TNIIIA2 were injected into the...

journal_title：Cartilage

authors： Hattori T,Hasegawa M,Unno H,Iino T,Fukai F,Yoshida T,Sudo A

更新日期：2020-03-23 00:00:00

abstract：:Articular cartilage injuries of the knee and ankle are common, and a number of different methods have been developed in an attempt to improve their repair. Clinically, there are 2 distinct aims of cartilage repair: 1) restoration of joint function and 2) prevention or at least delay of the onset of osteoarthritis. The...

journal_title：Cartilage

authors： McIlwraith CW,Fortier LA,Frisbie DD,Nixon AJ

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Cartilage health is thought to be dependent on the relationship between mechanics, structure, and metabolism, rather than these individual components in isolation. Due to sex differences in cartilage health, there is need to determine if the relationships between these cartilage components separately for male...

journal_title：Cartilage

authors： Harkey MS,Blackburn JT,Hackney AC,Lewek MD,Schmitz RJ,Pietrosimone B

更新日期：2020-09-19 00:00:00

abstract：OBJECTIVE:Articular cartilage is incapable of effective repair following injury or during osteoarthritis. While there have been developments in cartilage repair technologies, there is a need to advance biologically relevant models for preclinical testing of biomaterial and regenerative therapies. This study describes c...

journal_title：Cartilage

authors： Styczynska-Soczka K,Amin AK,Simpson AHW,Hall AC

更新日期：2020-06-21 00:00:00

abstract：:Nucleofection of chondrocytes has been shown to be an adequate method of transfection. Using Amaxa's nucleofection system, transfection efficiencies up to 89% were achievable for vector (pmaxGFP) and 98% for siRNA (siGLO) into passaged chondrocytes. However, such methods rely on costly commercial kits with proprietary...

journal_title：Cartilage

authors： Parreno J,Delve E,Andrejevic K,Paez-Parent S,Wu PH,Kandel R

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Delamination of the chondral surface of an osteochondral allograft (OCA) from the underlying cancellous bone has been described as a mode of failure after implantation in the knee. Our hypothesis was that increased storage time of the OCA is associated with increased risk of graft delamination after implan...

journal_title：Cartilage

authors： Rauck RC,Wang D,Tao M,Williams RJ

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To assess the clinical outcome of patients treated with autologous chondrocyte implantation using ChondroCelect in daily practice. METHODS:The study is a cross-sectional analysis of an open-label, noninterventional cohort. The setting was a compassionate use program, involving 43 orthopaedic centers in 7 Eur...

journal_title：Cartilage

authors： Vanlauwe J,Huylebroek J,Van Der Bauwhede J,Saris D,Veeckman G,Bobic V,Victor J,Almqvist KF,Verdonk P,Fortems Y,Van Lommel N,Haazen L

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:Osteoarthritis is a painful, chronic joint disease affecting man and animals with no known curative therapies. Palliative nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used but they cause adverse side effects prompting the search for safer alternatives. To address this need, we evaluated the anti...

journal_title：Cartilage

authors： Grzanna MW,Secor EJ,Fortuno LV,Au AY,Frondoza CG

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Our aim was to compare T2 with delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) in the hip and assess the reproducibility and effect of joint unloading on T2 mapping. DESIGN:Ten individuals at high risk of developing hip osteoarthritis (SibKids) underwent contemporaneous T2 mappi...

journal_title：Cartilage

authors： Fernquest S,Palmer A,Gammer B,Hirons E,Kendrick B,Taylor A,De Berker H,Bangerter N,Carr A,Glyn-Jones S

更新日期：2019-04-11 00:00:00

abstract：:Objective To evaluate the outcome of patients who have undergone simultaneous osteotomy and osteochondral allograft (OCA) transplantation. Our hypothesis is that use of high tibial osteotomy and fresh OCA in a combined procedure is safe and effective without increasing morbidity in comparison to OCA alone. Design A ca...

journal_title：Cartilage

authors： Hsu AC,Tirico LEP,Lin AG,Pulido PA,Bugbee WD

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:There are limited data on bone dimension and cartilage thickness of the distal humeral articular surface. This study aimed to evaluate sex- and age-related bone dimension and cartilage thickness differences and assess the effect of cartilage thickness on distal humeral shape. DESIGN:Elbow magnetic resonance ...

journal_title：Cartilage

authors： Misir A,Gunay AE,Oguzkaya S,Uzun E,Kizkapan TB,Yildiz KI,Ozcamdalli M

更新日期：2020-02-10 00:00:00

abstract：:Objective This study is a literature review from 2010 to 2014 concerning the quality of evidence in clinical trials about microfracture in attempt to repair articular cartilage. We have decided to focus on microfracturing, since this seems to be the best documented technique. Interest in evaluation of publication qual...

journal_title：Cartilage

authors： Frehner F,Benthien JP

更新日期：2018-10-01 00:00:00

abstract：:The objective of this study was to characterize magnetic resonance imaging (MRI) findings and correlate with clinical results in patients who underwent autologous chondrocyte implantation (ACI) of osteochondral lesions of the talus (OLT). METHODS:Twenty-four grafts were evaluated at a mean 65.8 months after ACI for O...

journal_title：Cartilage

authors： Chan KW,Ferkel RD,Kern B,Chan SS,Applegate GR

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Traumatic impacts on the articular joint surface in vitro are known to lead to degeneration of the cartilage. The main objective of this study was to develop a spring-loaded impact device that can be used to deliver traumatic impacts of consistent magnitude and rate and to find whether impacts cause catabolic...

journal_title：Cartilage

authors： Alexander PG,Song Y,Taboas JM,Chen FH,Melvin GM,Manner PA,Tuan RS

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Our aim is to explore the candidate pathogenesis genes and pathways of developmental dysplasia of hip (DDH). DESIGN:Proliferating primary chondrocytes from hip cartilage were used for total RNA extraction including 5 DDH patients and 5 neck of femur fracture (NOF) subjects. Genome-wide mRNA and microRNA (miR...

journal_title：Cartilage

authors： Cheng B,Jia Y,Wen Y,Hou W,Xu K,Liang C,Cheng S,Liu L,Chu X,Ye J,Yao Y,Zhang F,Xu P

更新日期：2021-02-01 00:00:00

abstract：:Purpose. To determine the 5-year success rate of the "all-inside" technique of arthroscopic meniscus suture and collagen membrane wrapping along with bone marrow blood injection, to evaluate the progression of degenerative changes and the impact of simultaneous anteriro cruciate ligament (ACL) reconstruction. Methods....

journal_title：Cartilage

authors： Ciemniewska-Gorzela K,Bąkowski P,Naczk J,Jakob R,Piontek T

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of intra-articular injection of autologous micronized adipose tissue (MAT) with ankle arthroscopic debridement in patients with advanced-stage posttraumatic osteoarthritis (PTOA) of ankle. DESIGN:A retrospective cohort study investigating patients treated with arthroscopic debridement ...

journal_title：Cartilage

authors： Shimozono Y,Dankert JF,Kennedy JG

更新日期：2020-08-06 00:00:00

abstract：OBJECTIVE:To evaluate clinical, functional, and radiographic outcomes of patients who underwent bipolar osteochondral allograft transplantation (OCAT) of the patellofemoral joint (PFJ). DESIGN:Prospectively collected data on 18 knees who underwent fresh osteochondral allograft transplantation of the patella and trochl...

journal_title：Cartilage

authors： Mirzayan R,Charles MD,Batech M,Suh BD,DeWitt D

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of accelerated compared with traditional postoperative weightbearing (WB) rehabilitation following matrix-induced autologous chondrocyte implantation (MACI) of the knee, using MRI. METHODS:A randomized controlled study design was used to assess MRI-based outcomes of MACI gra...

journal_title：Cartilage

authors： Ebert JR,Fallon M,Robertson WB,Lloyd DG,Zheng MH,Wood DJ,Ackland T

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Osteoarthritis (OA) is an incurable joint disease characterized by pronounced pain. MicroRNAs constitute epigenetic mechanisms that may affect OA progression by contributing to changes in chondrocyte phenotype. This study investigates for the first time whether there is a link between miRNA-1 (miR-1) and OA p...

journal_title：Cartilage

authors： Yang Y,Wang Y,Jia H,Li B,Xing D,Li JJ

更新日期：2020-11-20 00:00:00

abstract：OBJECTIVE:To assess the continued effectiveness and safety of Gel-200 following observation and open-label retreatment in an extension protocol following a randomized, double-blind, phosphate buffered saline (PBS)-controlled trial (initial treatment trial). DESIGN:Patients who completed initial blinded treatment were ...

journal_title：Cartilage

authors： Strand V,Baraf HS,Lavin PT,Lim S,Hosokawa H

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this article is to report on a distinctive pattern of linear femoral head chondral lesions that were observed in 7 patients who underwent hip arthroscopy for the treatment of mixed-type femoroacetabular impingement (FAI). DESIGN:Between 2010 and 2012, 702 patients were treated with hip arthros...

journal_title：Cartilage

authors： Philippon MJ,Goljan P,Devitt BM,Peixoto LP

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:A systematic review and meta-analysis of Autologous Matrix-Induced Chondrogenesis (AMIC®) outcomes for grade III/IV chondral and osteochondral lesions of the knee treated with Chondro-Gide®. DESIGN:Studies with a minimum follow-up of 1 year providing clinical results of AMIC repair in the knee were included ...

journal_title：Cartilage

authors： Steinwachs MR,Gille J,Volz M,Anders S,Jakob R,De Girolamo L,Volpi P,Schiavone-Panni A,Scheffler S,Reiss E,Wittmann U

更新日期：2019-09-11 00:00:00

abstract：:Objective To identify if the time of day and pre-imaging exercise matter while performing T2* mapping of hip joint cartilage at 3 T. Design Nine asymptomatic healthy volunteers (mean age 27.4 ± 4.0 years) with no obvious morphological evidence of cartilage damage were enrolled. The MRI protocol included a double-echo ...

journal_title：Cartilage

authors： Hesper T,Hosalkar HS,Schleich C,Antoch G,Welsch GH,Krauspe R,Zilkens C,Bittersohl B

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Full-depth cartilage lesions do not heal and the long-term clinical outcome is uncertain. In the symptomatic middle-aged (35-60 years) patient, treatment with metal implants has been proposed. However, the cartilage health surrounding these implants has not been thoroughly studied. Our objective was to evalu...

journal_title：Cartilage

authors： Martinez-Carranza N,Hultenby K,Lagerstedt AS,Schupbach P,Berg HE

更新日期：2019-01-01 00:00:00