Functional architecture of the nasopharyngeal tonsil.

Abstract:

:The exact architecture of the normal nasopharyngeal tonsil remains obscure because most histopathologic investigations have been based on surgically removed adenoids. We compared enlarged adenoids and normal nasopharyngeal tonsils under both light and electron microscopes. The marked features of clinically enlarged adenoids were a large extension of the reticular epithelium and increased germinal centers. A tendency toward increased stratified squamous epithelium and decreased ciliated epithelium was apparent in enlarged adenoids, possibly due to inflammatory conditions. One type of nonciliated cell seemed to transport foreign material into underlying lymphocytes, as do the M cells of gut-associated lymphoid tissue. This type of nonciliated cell was rarely found in the extended reticular epithelium of enlarged adenoids. These findings suggest a disturbance of the antigen-trapping system and surface protections in adenoidal enlargement.

journal_name

Am J Otolaryngol

authors

Fujiyoshi T,Watanabe T,Ichimiya I,Mogi G

doi

10.1016/0196-0709(89)90135-x

subject

Has Abstract

pub_date

1989-03-01 00:00:00

pages

124-31

issue

2

eissn

0196-0709

issn

1532-818X

pii

0196-0709(89)90135-X

journal_volume

10

pub_type

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