Computer-assisted predictive mathematical relationship among electroshock voltage and duration and occurrence of convulsion in mice.

Abstract:

:A microcomputer program in BASIC for predicting percentage of occurrence of electroshock-induced convulsion in mice was designed. A formula published by the author to express the mathematical relationship among the drug dose, the time, and the biological response was used in this program. Analysis of the actual, and the computer-assisted predicted percentages of occurrence of convulsion has shown that the program is fairly accurate in expressing convulsion response of mice as a function of the voltage and the duration.

authors

Chung SJ

doi

10.1016/0169-2607(89)90177-6

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

23-30

issue

1

eissn

0169-2607

issn

1872-7565

pii

0169-2607(89)90177-6

journal_volume

28

pub_type

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