Human exposure to toxic metals via contaminated dust: Bio-accumulation trends and their potential risk estimation.

Abstract:

:We assessed the levels of potentially toxic trace metals, Zinc (Zn), Lead (Pb), Manganese (Mn), Copper (Cu), Nickel (Ni), Chromium (Cr), Cobalt (Co), and Cadmium (Cd), in dust, hair, nail and serum, sampled in rural, urban and industrial areas of Punjab, Pakistan. Trace metals occurrence in all samples, in descending order, was: Zn, Pb, Mn, Cu, Cr, Ni, Co, Cd. The samples from the urban areas showed significantly higher concentration of toxic trace metals (Zn, Ni, Cr, Co, Mn, and Cd) than those from industrial (which conversely had higher levels of Pb and Cu), and than samples from rural areas. Bioaccumulation patterns showed that dust exposure is one of the major routes into human body for Cd, Pb, Co, Mn and Cr, while the burden of Zn, Cu, and Ni can be more linked to dietary sources. The concentrations of trace metals in the samples from Punjab were comparable and/or higher than those reported worldwide. In many cases, the levels of Zn, Cr, Pb, Ni and Cd in hair and nail were beyond the ATSDR threshold guideline values that may cause some serious health effects. Hazard Index (HI) calculated for trace metal concentrations in the human population of Punjab points particularly to health risks from Cd (for children in urban and industrial areas) and from Pb (for all sub-groups).

journal_name

Chemosphere

journal_title

Chemosphere

authors

Mohmand J,Eqani SA,Fasola M,Alamdar A,Mustafa I,Ali N,Liu L,Peng S,Shen H

doi

10.1016/j.chemosphere.2015.03.004

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

142-51

eissn

0045-6535

issn

1879-1298

pii

S0045-6535(15)00202-7

journal_volume

132

pub_type

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