Abstract:
OBJECTIVES:To prospectively examine associations between accelerometer-measured physical activity (PA) and mortality in older women, with an emphasis on light-intensity PA. DESIGN:Prospective cohort study with baseline data collection between March 2012 and April 2014. SETTING:Women's Health Initiative cohort in the United States. PARTICIPANTS:Community-dwelling women aged 63 to 99 (N = 6,382). MEASUREMENTS:Minutes per day of usual PA measured using hip-worn triaxial accelerometers, physical functioning measured using the Short Physical Performance Battery, mortality follow-up for a mean 3.1 years through September 2016 (450 deaths). RESULTS:When adjusted for accelerometer wear time, age, race-ethnicity, education, smoking, alcohol, self-rated health, and comorbidities, relative risks (95% confidence intervals) for all-cause mortality across PA tertiles were 1.00 (referent), 0.86 (0.69, 1.08), 0.80 (0.62, 1.03) trend P = .07, for low light; 1.00, 0.57 (0.45, 0.71), 0.47 (0.35, 0.61) trend P < .001, for high light; and, 1.00, 0.63 (0.50, 0.79), 0.42 (0.30, 0.57) trend P < .001, for moderate-to-vigorous PA (MVPA). Associations remained significant for high light-intensity PA and MVPA (P < .001) after further adjustment for physical function. Each 30-min/d increment in light-intensity (low and high combined) PA and MVPA was associated, on average, with multivariable relative risk reductions of 12% and 39%, respectively (P < .01). After further simultaneous adjusting for light intensity and MVPA, the inverse associations remained significant (light-intensity PA: RR = 0.93, 95% CI = 0.89-0.97; MVPA: RR = 0.67, 95% CI = 0.58-0.78). These relative risks did not differ between subgroups for age or race and ethnicity (interaction, P ≥ .14, all). CONCLUSION:When measured using accelerometers, light-intensity and MVPA are associated with lower mortality in older women. These findings suggest that replacing sedentary time with light-intensity PA is a public health strategy that could benefit an aging society and warrants further investigation.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
LaMonte MJ,Buchner DM,Rillamas-Sun E,Di C,Evenson KR,Bellettiere J,Lewis CE,Lee IM,Tinker LF,Seguin R,Zaslovsky O,Eaton CB,Stefanick ML,LaCroix AZdoi
10.1111/jgs.15201subject
Has Abstractpub_date
2018-05-01 00:00:00pages
886-894issue
5eissn
0002-8614issn
1532-5415journal_volume
66pub_type
杂志文章abstract:OBJECTIVES:To report on the efficacy, safety, and tolerability of sertraline in the treatment of elderly depres-sed patients with and without comorbid medical illness. SETTING:Multicenter. DESIGN:Randomized, double-blind, placebo-controlled study. PARTICIPANTS:A total of 752 patients aged 60 and older with diagnosis...
journal_title:Journal of the American Geriatrics Society
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更新日期:2004-01-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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更新日期:1995-09-01 00:00:00
abstract::The relationship between atrial natriuretic peptide (ANP) and age was studied. In elderly subjects (65 to 84 years) higher basal ANP levels were found as compared with those found in young subjects (21 to 23 years). Volume loading (750 mL 0.9% NaCl in 60 minutes) increased ANP levels only in the aged group, and plasma...
journal_title:Journal of the American Geriatrics Society
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更新日期:1990-11-01 00:00:00
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doi:10.1111/j.1532-5415.2010.02819.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:This study intends to determine what role fiberoptic bronchoscopy (FOB) plays in the diagnosis of tuberculosis (TB), particularly in a geriatric population. DESIGN:Cases of tuberculosis reported to the Tennessee Department of Health during the years 1989 and 1990 were divided into two age groups: Group A (< ...
journal_title:Journal of the American Geriatrics Society
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更新日期:1993-06-01 00:00:00
abstract:OBJECTIVES:To determine how many individual patient data (IPD) reviews that included older people were available in MEDLINE and whether the effectiveness of treatments differed between older and younger individuals. DESIGN:Overview of IPD reviews. SETTING:A MEDLINE search was conducted for IPD reviews of randomized c...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
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更新日期:2014-06-01 00:00:00
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更新日期:1987-03-01 00:00:00
abstract:OBJECTIVES:To compare reports about care experiences of individuals who died within 1 year of survey with reports of those who did not. DESIGN:Medicare Advantage (MA) Consumer Assessment of Healthcare Providers and Systems (CAHPS) surveys asked about care experiences. Survey completion dates were linked to Social Secu...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
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更新日期:2013-03-01 00:00:00
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更新日期:2015-05-01 00:00:00
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更新日期:2018-03-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1992-02-01 00:00:00
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更新日期:2012-03-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
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更新日期:1998-06-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2002-02-01 00:00:00
abstract:OBJECTIVES:To estimate prescribing tends of and correlates independently associated with high-risk anticholinergic prescriptions in adults aged 65 and older in office-based outpatient visits. DESIGN:Repeated cross-sectional analysis. SETTING:National Ambulatory Medical Care Survey (NAMCS). PARTICIPANTS:A national sa...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15357
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:To examine recent trends in discharge disposition after hospitalization for hip fracture. DESIGN:Retrospective observational study using data from the 5% random sample of Medicare claims data from 2001 to 2005 that the Centers for Medicare and Medicaid Services makes available for research purposes. SETTIN...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
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更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:To compare cognitive performance among Japanese and American persons, aged 68 years and older, using two nationally representative studies and to examine whether differences can be explained by differences in the distribution of risk factors or in their association with cognitive performance. DESIGN:National...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:To explore the risk of developing Alzheimer's disease (AD) in individuals with diabetes mellitus treated with metformin or other antidiabetic drugs. DESIGN:Case-control study. SETTING:The United Kingdom-based General Practice Research Database (GPRD), a well-established primary care database. PARTICIPANTS...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.03916.x
更新日期:2012-05-01 00:00:00