Abstract:
:The incidence, ecology, and mortality of gram-negative bacillary bacteremia in elderly patients were studied in an analysis of 334 episodes over a four-year-period in a 489-bed North Carolina community teaching hospital, 135 (40.4%) of which occurred in patients 70 years of age or older. The bacteremia rate per 1000 hospital admissions increased sharply with increasing age. The ecology and in vitro antimicrobial susceptibilities of the bacterial isolates were strongly influenced by community v hospital acquisition, but not by age. Urosepsis was significantly more likely to be the underlying source of hospital-acquired bacteremia in patients 70 years or older (P less than 0.01). Total bacteremia-related mortality did not increase with increasing age; in the group of patients aged 70 years or older with nonfatal/ultimately fatal underlying diseases (NF/UFUD), however, mortality was 9.1% compared to 2.9% in the younger age group (P less than 0.001). Significantly increased bacteremia-related mortality was also noted in the older patients with NF/UFUD admitted from nursing homes (P less than 0.05) and those not treated with an appropriate antimicrobial agent within 24 hours (P less than 0.01). Overall, the older patients with hospital-acquired bacteremia, neutropenia-associated infection, those bacteremic from a nonurinary source of infection, and those treated with multiple-drug regimens had higher mortality (P less than 0.05). Gram-negative bacteremia is much more common in patients 70 years of age or older and compared with younger patients mortality appears to be significantly increased for the important subgroup of older patients with nonfatal or ultimately fatal underlying diseases.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
McCue JDdoi
10.1111/j.1532-5415.1987.tb02311.xsubject
Has Abstractpub_date
1987-03-01 00:00:00pages
213-8issue
3eissn
0002-8614issn
1532-5415journal_volume
35pub_type
杂志文章abstract:BACKGROUND/OBJECTIVES:To optimize health and well-being for all older people, we must collectively develop leaders to pioneer models of care, educate the healthcare workforce, advance research, and engage the community. METHODS:The Emerging Leaders in Aging (ELIA) program was created to train a multiprofessional cadre...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15702
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the effectiveness of wheelchair assessment and configuration on pressure injury incidence, mobility, and functioning in a wheelchair. DESIGN:Randomized controlled trial with participants individually randomized into intervention and control groups. SETTING:Nursing home. PARTICIPANTS:Nursing ho...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/jgs.15495
更新日期:2018-09-01 00:00:00
abstract::This clinical, practice-based study explores the research question: Is there a relationship between hearing loss and functional disturbance in elderly patients? We analyzed the impact of hearing impairment on 153 patients over 65 years of age screened in primary care practice. Functional and psychosocial impairment we...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1989.tb05870.x
更新日期:1989-02-01 00:00:00
abstract:OBJECTIVES:To estimate in a community-dwelling elderly population the magnitude of renal function misclassification, occurring when persons with normal serum creatinine have reduced glomerular filtration rate (GFR), and to describe the participant characteristics related to misclassification. DESIGN:Cross-sectional. ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2007.01196.x
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:To examine the effect of interventions to optimize medication use on adverse drug reactions (ADRs) in older adults. DESIGN:Systematic review and meta-analysis. EMBASE, PubMed, OVID, Cochrane Library, Clinicaltrials.gov, and Google Scholar were searched through April 30, 2017. SETTING:Randomized controlled ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,meta分析
doi:10.1111/jgs.15195
更新日期:2018-02-01 00:00:00
abstract::Physical performance measures, including cardiopulmonary exercise testing (CPXT), are widely used in geriatric practice and aging research. Theoretically, research participants and study personnel could get infected in the closed environment of the exercise laboratory by contact with respiratory droplets from an infec...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16968
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:To determine whether function-related indicators (FRIs), derived from preadmission claims data, help explain the frequent practice of forgoing secondary prevention medications observed in Medicare. DESIGN:Retrospective cohort. SETTING:National Medicare data. PARTICIPANTS:Elderly Medicare beneficiaries dis...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13953
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:To identify the strategies used by older persons to cope with chronic noncancer pain, determine the perceived effectiveness of the strategies, and ascertain factors associated with their use. DESIGN:Cross-sectional telephone survey. SETTING:Primary care practice located at a Veterans Affairs Medical Center...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2004.52263.x
更新日期:2004-06-01 00:00:00
abstract::Most estimates of the cost of informal caregiving in patients with Alzheimer's disease (AD) remain cross-sectional. Longitudinal estimates of informal caregiving hours and costs are less frequent and are from assessments covering only short periods of time. The objectives of this study were to estimate long-term traje...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2006.00871.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:To demonstrate reliability and feasibility of a standardized protocol to assess and score quality indicators relevant to pressure ulcer (PU) care processes in nursing homes (NHs). DESIGN:Descriptive. SETTING:Eight NHs. PARTICIPANTS:One hundred ninety-one NH residents for whom the PU Resident Assessment Pr...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2003.51402.x
更新日期:2003-09-01 00:00:00
abstract::Frailty is a common and central problem of old age. Recent research has defined frailty as an accumulation of deficits or as a distinct clinical syndrome involving specific comorbid physical disorders and functional impairment, but the psychological aspects of frailty have received little attention. It is proposed tha...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.02104.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:To evaluate survival and causes of death in subjects with idiopathic senile gait disorders. DESIGN:A population-based longitudinal study. SETTING:Survival analysis of the oldest old within the Leiden 85-plus Study. PARTICIPANTS:We distinguished three different groups according to their gait: subjects with...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb04786.x
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To determine if alcohol use is a risk factor for fall injury events among community-dwelling older persons. DESIGN:Case-control study. SETTING:South Miami Beach, Florida. PARTICIPANTS:320 persons 65 or older who sought treatment at six area hospitals for injuries resulting from falls; 609 controls, matched...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1992.tb01955.x
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVES:To develop a prediction model for kidney transplantation (KT) outcomes specific to older adults with end-stage renal disease (ESRD) and to use this model to estimate the number of excellent older KT candidates who lack access to KT. DESIGN:Secondary analysis of data collected by the United Network for Organ...
journal_title:Journal of the American Geriatrics Society
pub_type: 社论,多中心研究
doi:10.1111/j.1532-5415.2011.03652.x
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:To examine the effect of mode of survey administration on response rates and response tendencies for the Consumer Assessment of Healthcare Providers and Systems (CAHPS) Hospice Survey and develop appropriate adjustments. DESIGN:Survey response data were obtained after sampling and fielding of the CAHPS Hosp...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15265
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:The Centers for Medicare & Medicaid Services (CMS) Nursing Home Quality Initiative aims to improve quality through performance measurement. We describe quality improvement (QI) changes that skilled nursing facilities (SNFs) reported making in response to CMS performance measurements and whether reported QI c...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16466
更新日期:2020-09-01 00:00:00
abstract:BACKROUND:Baseline depressive symptoms have been consistently associated with the onset of cardiovascular disease (CVD). OBJECTIVES:Since depressive symptoms vary over time in elderly persons, and to help clarify whether or not depression is an etiological factor for CVD, we quantified the association between the cour...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.13872
更新日期:2016-01-01 00:00:00
abstract::Cognitive function is often impaired in type I diabetes mellitus, especially when onset is in early childhood. Limited evidence suggests similar impairment in the much larger population of older persons with type II diabetes. We report here the results of 13 measures of mental efficiency in persons between 65 and 77 y...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1990.tb02398.x
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of psychotropic medication withdrawal and a home-based exercise program in reducing falls in older people. DESIGN:A randomized controlled trial with a two by two factorial design. SETTING:Seventeen general practices in Dunedin, New Zealand. PARTICIPANTS:Women and men aged 65 yea...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1532-5415.1999.tb03843.x
更新日期:1999-07-01 00:00:00
abstract::The influence of aging on serum levels of gonadotropins (FSH and LH), testosterone and estradiol was studied in the following groups: 4 normal men (ages 30 to 50), 38 men with symptoms of the male climacteric (ages 51 to 84), 25 men with relative impotence (ages 31 to 50), 10 normal women (ages 24 to 31), and 6 menopa...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1976.tb04294.x
更新日期:1976-04-01 00:00:00
abstract:OBJECTIVES:To describe the prevalence of coexisting conditions that affect clinical decision-making in adults with coronary heart disease (CHD). DESIGN:Cross-sectional. SETTING:National Health and Nutrition Examination Survey, 1999 to 2004. PARTICIPANTS:Eight thousand six hundred fifty-four people aged 45 and older;...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03391.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:To determine whether genetic variants in the ciliary neurotrophic factor (CNTF) gene are associated with muscle strength in older women. DESIGN:Cross-sectional analysis of baseline data from the Women's Health and Aging Studies I (1992) and II (1994), complementary population-based studies. SETTING:Twelve ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00693.x
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the use of newer psychotropic agents in nursing home residents in the era of new Health Care Financing Administration (HCFA) guidelines. DESIGN:Retrospective chart review of referrals to an on-site geriatric psychiatry service in seven Eastern Massachusetts facilities during 1995-1996. SUBJECTS:...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1998.tb02540.x
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVES:To describe the prevalence of visual and auditory impairment in frail older persons and to evaluate the association between sensory impairment and overall functional status. DESIGN:Prospective patient evaluation and retrospective analysis of data. SETTING:The outpatient geriatric assessment clinic of a uni...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1999.tb07432.x
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVES:To identify factors associated with incomplete bladder emptying in older women with overactive bladder (OAB) symptoms. DESIGN:Retrospective medical records review. SETTING:Urodynamic laboratory at a large academic health care system in the southeast United States. PARTICIPANTS:Medical records from women a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13474
更新日期:2015-07-01 00:00:00
abstract::Thirty-nine male patients (median age 61, range 19-92) from a neurologic ward were examined by a test for prosopo-affective agnosia (PAA), i.e., impairment in the recognition of facial affect (emotions) with no impairment in the recognition of facial features (PA, prosopo-agnosia). The scores for patients without hemi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1980.tb01123.x
更新日期:1980-10-01 00:00:00
abstract:OBJECTIVE:To investigate whether a marked decrease in postprandial systolic blood pressure correlates with a higher incidence of falls, syncope, new coronary events, new stroke, and total mortality at long-term follow-up in older nursing home residents. DESIGN:In a prospective study of 499 nursing home residents aged ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1997.tb05965.x
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Elderly adults (65 years of age and older) are of particular concern for traumatic amputations due to age-related changes in vision and coordination, making them more susceptible to injury. OBJECTIVES:The objective of this study is to describe the epidemiology of traumatic amputations in the elderly adults ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13889
更新日期:2016-01-01 00:00:00
abstract::Research indicates that lower extremity muscle weakness in the elderly is consistently related to impaired mobility and fall risk. Reversible components of the muscle weakness of aging include underuse syndromes and undernutrition, both of which are prevalent in nursing home populations. The Boston FICSIT study is a n...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1993.tb06714.x
更新日期:1993-03-01 00:00:00
abstract:OBJECTIVE:To examine physician use of stool guaiac testing in order to determine indications for testing, how the test was used, and the consequences of a particular test result. DESIGN:Retrospective case series. SETTING:Large midwestern inpatient nursing home facility. PATIENTS:All patients with positive fecal occu...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1991.tb03569.x
更新日期:1991-12-01 00:00:00