Apnea testing using the oxygen insufflation method for diagnosis of brain death may compromise pulmonary function.

Abstract:

INTRODUCTION:The aim of our study was to compare the reliability and safety of the classical I-AT with the continuous positive airway pressure apnea test (CPAP-AT). MATERIAL AND METHODS:In the group of 48 patients (group O), an I-AT was performed at the end of BD diagnostic procedures, and approximately 1-1.5h later CPAP-AT with 100% FiO2 and CPAP of 10cm H2O, provided by ventilator in CPAP mode. After pre‑oxygenation with 100% FiO2 for 10min, the PaO2/FiO2 ratio was recorded prior to I-AT at time-point one (T1) and prior to CPAP-AT at time-point two (T2). Group O was categorized into subgroup N-H (non-hypoxemic), consisting of 41 patients with good lung function, and subgroup H (hypoxemic) consisting of 7 patients with poor lung function. Within each subgroup PaO2/FiO2 at T1 and T2 were compared. RESULTS:In Group O, PaO2/FiO2 decreased from 321±128mmHg at T1 to 291±119mmHg at T2 (p=0.004). In subgroup N-H, PaO2/FiO2 declined from 355±103 to 321±100mmHg (p=0.008), and in subgroup H, PaO2/FiO2 remained almost unchanged. Additionally, in 4 patients from subgroup N-H, PaO2/FiO2 decreased below 200mmHg at T2. CONCLUSIONS:Our study indicates that I-AT may compromise pulmonary function and this may support the recommendation of safer CPAP-AT alternative.

journal_name

J Crit Care

journal_title

Journal of critical care

authors

Sołek-Pastuszka J,Sawicki M,Iwańczuk W,Kojder K,Saucha W,Czajkowski Z,Chełstowski K,Bohatyrewicz R

doi

10.1016/j.jcrc.2017.10.038

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

175-178

eissn

0883-9441

issn

1557-8615

pii

S0883-9441(17)31203-0

journal_volume

44

pub_type

杂志文章
  • Changing trends in the use of seizure prophylaxis after traumatic brain injury: a shift from phenytoin to levetiracetam.

    abstract:PURPOSE:Current guidelines for traumatic brain injury (TBI) recommend antiepileptic drugs (AEDs) for 7 days after injury to decrease posttraumatic seizure risk. Phenytoin decreases seizure risk 73% vs placebo during this time. Levetiracetam (LEV) is an alternative; however, no published data validate comparable efficac...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2012.11.020

    authors: Kruer RM,Harris LH,Goodwin H,Kornbluth J,Thomas KP,Slater LA,Haut ER

    更新日期:2013-10-01 00:00:00

  • Accelerometer-based devices can be used to monitor sedation/agitation in the intensive care unit.

    abstract:PURPOSE:Monitoring sedation/agitation levels in patients in the intensive care unit (ICU) are important to direct treatment and to improve outcomes. This study was designed to determine the potential use of accelerometer-based sensors/devices to objectively measure sedation/agitation in patients admitted to the ICU. M...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2014.05.014

    authors: Raj R,Ussavarungsi K,Nugent K

    更新日期:2014-10-01 00:00:00

  • Acid-base disturbances in acute poisoning and their association with survival.

    abstract:PURPOSE:The purpose was to investigate the association between acid-base disturbances and mortality in acute poisoning. MATERIALS AND METHODS:We performed a retrospective cross-sectional exploratory study on all acutely poisoned patients older than 12 years who had been admitted to the main tertiary toxicology hospita...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2016.05.003

    authors: Hamdi H,Hassanian-Moghaddam H,Hamdi A,Zahed NS

    更新日期:2016-10-01 00:00:00

  • Risk factors for noninvasive ventilation failure in patients with acute cardiogenic pulmonary edema: A prospective, observational cohort study.

    abstract:PURPOSE:We identified risk factors for noninvasive ventilation (NIV) failure in patients with acute cardiogenic pulmonary edema (ACPE). MATERIALS AND METHODS:We conducted an observational cohort study over a 3-year period in a 28-bed emergency intensive care unit (EICU) and prospectively included all consecutive patie...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2017.01.001

    authors: Luo Z,Han F,Li Y,He H,Yang G,Mi Y,Ma Y,Cao Z

    更新日期:2017-06-01 00:00:00

  • Multiple-organ effect of normobaric hyperoxia in neonatal rats.

    abstract:PURPOSE:Prolonged exposure to normobaric hyperoxia (NH) is associated with blood leukocyte activation and sequestration in the lung. Whether NH-induced leukocyte activation and sequestration can affect extrapulmonary organs or blood cellular profile has not been systematically investigated. We studied simultaneous chan...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2005.09.057

    authors: Torbati D,Tan GH,Smith S,Frazier KS,Gelvez J,Fakioglu H,Totapally BR

    更新日期:2006-03-01 00:00:00

  • Continuous jugular bulb venous oxygen saturation validation and variations during intracranial aneurysm surgery.

    abstract:PURPOSE:During intracranial aneurysm surgery, numerous factors may alter cerebral blood flow and oxygen supply-demand balance. Continuous monitoring of jugular bulb venous oxygen saturation (SvjO2) may help in the anesthetic management of such procedures. MATERIALS AND METHODS:Fiberoptic SvjO2 was continuously monitor...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/s0883-9441(97)90040-x

    authors: Clavier N,Schurando P,Raggueneau JL,Payen DM

    更新日期:1997-09-01 00:00:00

  • Biophilosophical basis for identifying the death of a person.

    abstract::The capacity for consciousness and self-awareness is uniquely synonymous with human life and personhood, and its absence is necessary and sufficient to identify that death has occurred. The presence of these functions is uniquely synonymous with human life. Ongoing organ function, response to infection, growth, wound ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2014.04.013

    authors: Baker A,Shemie SD

    更新日期:2014-08-01 00:00:00

  • Plasma neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in adult critically ill patients: a prospective study.

    abstract:PURPOSE:The aim of the study was to assess the ability of plasma neutrophil gelatinase-associated lipocalin (pNGAL) to predict acute kidney injury (AKI) in adult intensive care unit (ICU) patients. METHODS:All consecutives patients admitted to 3 ICUs were enrolled in this prospective-observational study. Plasma neutro...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2009.05.010

    authors: Constantin JM,Futier E,Perbet S,Roszyk L,Lautrette A,Gillart T,Guerin R,Jabaudon M,Souweine B,Bazin JE,Sapin V

    更新日期:2010-03-01 00:00:00

  • Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients.

    abstract:OBJECTIVE:Serum concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, may contribute to endothelial dysfunction and organ failure in sepsis. We aimed at investigating ADMA levels as a potential diagnostic or prognostic biomarker in critically ill patients. METHODS:Two ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2013.05.016

    authors: Koch A,Weiskirchen R,Kunze J,Dückers H,Bruensing J,Buendgens L,Matthes M,Luedde T,Trautwein C,Tacke F

    更新日期:2013-12-01 00:00:00

  • Core temperature variation is associated with heart rate variability independent of cardiac index: a study of 278 trauma patients.

    abstract:PURPOSE:The purpose of this study is to determine if temperature extremes are associated with reduced heart rate variability (HRV) and "cardiac uncoupling." MATERIALS AND METHODS:This was a retrospective, observational cohort study performed on 278 trauma intensive care unit admissions that had continuous HR, cardiac ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2010.11.008

    authors: Mowery NT,Morris JA Jr,Jenkins JM,Ozdas A,Norris PR

    更新日期:2011-10-01 00:00:00

  • African American race, obesity, and blood product transfusion are risk factors for acute kidney injury in critically ill trauma patients.

    abstract:PURPOSE:Acute kidney injury (AKI) is a common source of morbidity after trauma. We sought to determine novel risk factors for AKI, by Acute Kidney Injury Network (AKIN) criteria, in critically ill trauma patients. MATERIALS AND METHODS:A prospective cohort of 400 patients admitted to the intensive care unit of a level...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2012.02.002

    authors: Shashaty MG,Meyer NJ,Localio AR,Gallop R,Bellamy SL,Holena DN,Lanken PN,Kaplan S,Yarar D,Kawut SM,Feldman HI,Christie JD

    更新日期:2012-10-01 00:00:00

  • Choice of renal replacement therapy modality in intensive care units: data from a Japanese Nationwide Administrative Claim Database.

    abstract:PURPOSE:This study was undertaken to assess recent trends of the choice of renal replacement therapy (RRT) modalities in Japanese intensive care units (ICUs). MATERIALS AND METHODS:Data were extracted from the Japanese Diagnosis Procedure Combination database for 2011. We identified adult patients without end-stage re...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2014.11.003

    authors: Iwagami M,Yasunaga H,Noiri E,Horiguchi H,Fushimi K,Matsubara T,Yahagi N,Nangaku M,Doi K

    更新日期:2015-04-01 00:00:00

  • Predictors of extraventricular drain-associated bacterial ventriculitis.

    abstract:PURPOSE:Bacterial ventriculitis (BV) may develop in patients requiring external ventricular drains (EVDs). The purpose of this study was to determine predictors of EVD-associated BV onset. MATERIALS AND METHODS:A retrospective review of Duke University Hospital patients with EVD device placement between January 2005 a...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2013.08.012

    authors: Williamson RA,Phillips-Bute BG,McDonagh DL,Gray MC,Zomorodi AR,Olson DM,Britz GW,Laskowitz DT,James ML

    更新日期:2014-02-01 00:00:00

  • Inflammatory lung edema correlates with echocardiographic estimation of capillary wedge pressure in newly diagnosed septic patients.

    abstract:PURPOSE:Lung ultrasound is an accurate and accessible tool to quantify lung edema. Furthermore, left ventricle filling pressures (LVFP) can be assessed with transthoracic echocardiography (TTE) by the E/e' ratio (E/e'). The present study aimed to assess the correlation between E/e' and lung edema quantified by a simpli...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2017.11.036

    authors: Santos TM,Franci D,Gontijo-Coutinho CM,Ozahata TM,de Araújo Guerra Grangeia T,Matos-Souza JR,Carvalho-Filho MA

    更新日期:2018-04-01 00:00:00

  • Mobilization of ventilated patients in the intensive care unit: An elicitation study using the theory of planned behavior.

    abstract:PURPOSE:Early mobilization in intensive care unit (ICU) is safe, feasible, and beneficial. However, mobilization frequently does not occur in practice. The study objective was to elicit attitudinal, normative, and control beliefs (barriers and enablers) toward the mobilization of ventilated patients, to inform developm...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2015.08.010

    authors: Holdsworth C,Haines KJ,Francis JJ,Marshall A,O'Connor D,Skinner EH

    更新日期:2015-12-01 00:00:00

  • Reasons underlying interhospital transfers to an academic medical intensive care unit.

    abstract:PURPOSE:Interhospital critical care transfers are common, yet few studies address the underlying reasons for transfers. We examined clinician and patient/surrogate perceptions about interhospital transfers and assessed their agreement on these transfers. MATERIALS AND METHODS:This is a mixed-mode survey of 3 major sta...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2012.07.027

    authors: Wagner J,Iwashyna TJ,Kahn JM

    更新日期:2013-04-01 00:00:00

  • A noninvasive method for monitoring cerebral perfusion during cardiopulmonary resuscitation.

    abstract:PURPOSE:This study evaluates the use of transcranial Doppler (TCD) ultrasound in assessing the changes experienced by the cerebral circulation during cardiopulmonary resuscitation (CPR) and compares it with measurements of internal carotid artery (ICA) flow rates (ultrasonic flow-meter measurements) and cerebral blood ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/0883-9441(94)90013-2

    authors: Lewis LM,Stothert JC Jr,Gomez CR,Ruoff BE,Hall IS,Chandel B,Standeven J

    更新日期:1994-09-01 00:00:00

  • A prospective study of fungal biomarkers to improve management of invasive fungal diseases in a mixed specialty critical care unit.

    abstract:PURPOSE:The diagnosis of invasive fungal diseases (IFD) in critical care patients (CrCP) is difficult. The study investigated the performance of a set of biomarkers for diagnosis of IFD in a mixed specialty critical care unit (CrCU). METHODS:A prospective observational study in patients receiving critical care for ≥7d...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2017.03.025

    authors: Talento AF,Dunne K,Joyce EA,Palmer M,Johnson E,White PL,Springer J,Loeffler J,Ryan T,Collins D,Rogers TR

    更新日期:2017-08-01 00:00:00

  • Increased atrial contraction contribution to left ventricular filling during early septic shock.

    abstract:PURPOSE:To assess the atrial systolic function and the contribution of atrial contraction to left ventricular (LV) filling in septic shock patients as compared with healthy volunteers. METHODS:Twenty-seven septic patients evaluated during first 48 h of ICU admission and compared with 27 healthy volunteers. Left atrial...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2019.09.006

    authors: Monge García MI,Del Rio Lechuga A,Fletcher N,Gil Cano A

    更新日期:2019-12-01 00:00:00

  • Secondary EMR data for quality improvement and research: A comparison of manual and electronic data collection from an integrated critical care electronic medical record system.

    abstract:PURPOSE:This study measured the quality of data extracted from a clinical information system widely used for critical care quality improvement and research. MATERIALS AND METHODS:We abstracted data from 30 fields in a random sample of 207 patients admitted to nine adult, medical-surgical intensive care units. We asses...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2018.07.021

    authors: Brundin-Mather R,Soo A,Zuege DJ,Niven DJ,Fiest K,Doig CJ,Zygun D,Boyd JM,Parsons Leigh J,Bagshaw SM,Stelfox HT

    更新日期:2018-10-01 00:00:00

  • Extracorporeal membrane oxygenation in Korea - Trends and impact of hospital volume on outcome: Analysis of national insurance data 2009-2014.

    abstract:PURPOSE:ECMO use has increased lately. However, differences between adult ECMO and non-ECMO patients admitted to the ICU remain unstudied. In terms of volume-outcome relationship, the impact of ECMO volume on survival has not been validated in a real world cohort. MATERIALS AND METHODS:Retrospective analysis of data f...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2018.09.035

    authors: Tay CK,Cho YH,Park J,Yang JH,Chung CR,Sung K,Cho J,Kang D,Park H,Suh GY

    更新日期:2019-02-01 00:00:00

  • Early nutritional inadequacy is associated with psoas muscle deterioration and worse clinical outcomes in critically ill surgical patients.

    abstract:PURPOSE:To explore whether psoas cross sectional area (CSA) and density (Hounsfield Units, HU) are associated with nutritional adequacy and clinical outcomes in surgical intensive care unit patients. MATERIALS AND METHODS:Subjects with at least one CT scan within 72h of ICU admission were included. Demographic, nutrit...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2017.12.027

    authors: Yeh DD,Ortiz-Reyes LA,Quraishi SA,Chokengarmwong N,Avery L,Kaafarani HMA,Lee J,Fagenholz P,Chang Y,DeMoya M,Velmahos G

    更新日期:2018-06-01 00:00:00

  • Change in right ventricular systolic function after continuous renal replacement therapy initiation and renal recovery.

    abstract:OBJECTIVE:To describe the associations between right ventricular (RV) function and outcomes of patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). METHODS:This is a retrospective study, conducted 2006-2015 at an academic hospital in USA. We included patients with AKI requirin...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2020.11.022

    authors: Shawwa K,Kompotiatis P,Wiley BM,Jentzer JC,Kashani KB

    更新日期:2020-11-30 00:00:00

  • The impact of delayed rapid response call activation on patient outcomes.

    abstract:PURPOSE:To investigate the impact of delay in rapid response call (RRC) activation on Hospital mortality. MATERIALS AND METHODS:This study was conducted in a university affiliated hospital providing medical, surgical, mental health, maternity, and pediatric services. RRCs were considered delayed if RRC activation was ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2017.05.006

    authors: Gupta S,Green C,Subramaniam A,Zhen LD,Low E,Tiruvoipati R

    更新日期:2017-10-01 00:00:00

  • Changes of central venous oxygen saturation define fluid responsiveness in patients with septic shock: A prospective observational study.

    abstract:PURPOSE:To evaluate whether the changes of central venous oxygen saturation (Scvo2) after fluid challenge can define fluid responsiveness in patients with septic shock. METHODS:In this prospective observational study, septic shock patients with invasive cardiac output monitoring requiring fluid challenge were included...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2016.09.030

    authors: Xu B,Yang X,Wang C,Jiang W,Weng L,Hu X,Peng J,Du B

    更新日期:2017-04-01 00:00:00

  • How is life support withdrawn in intensive care units: A narrative review.

    abstract:PURPOSE:Decisions to withdraw life-sustaining therapy (WDLS) are relatively common in intensive care units across Canada. As part of preliminary work to develop guidelines for WDLS, we performed a narrative review of the literature to identify published studies of WDLS. MATERIALS AND METHODS:A search of MEDLINE and EM...

    journal_title:Journal of critical care

    pub_type: 杂志文章,评审

    doi:10.1016/j.jcrc.2016.04.006

    authors: Delaney JW,Downar J

    更新日期:2016-10-01 00:00:00

  • Temperature control in critically ill patients with fever: A meta-analysis of randomized controlled trials.

    abstract:PURPOSE:Fever is frequently encountered in ICU. It is unclear if targeted temperature control is beneficial in critically ill patients with suspected or confirmed infection. We conducted a systemic review and meta-analysis to answer this question. METHODS:We systematically reviewed major databases before January 2020 ...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2020.10.016

    authors: Sakkat A,Alquraini M,Aljazeeri J,Farooqi MAM,Alshamsi F,Alhazzani W

    更新日期:2021-02-01 00:00:00

  • Informed consent procedures in patients with an acute inability to provide informed consent: Policy and practice in the CENTER-TBI study.

    abstract:PURPOSE:Enrolling traumatic brain injury (TBI) patients with an inability to provide informed consent in research is challenging. Alternatives to patient consent are not sufficiently embedded in European and national legislation, which allows procedural variation and bias. We aimed to quantify variations in informed co...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2020.05.004

    authors: van Wijk RPJ,van Dijck JTJM,Timmers M,van Veen E,Citerio G,Lingsma HF,Maas AIR,Menon DK,Peul WC,Stocchetti N,Kompanje EJO,CENTER-TBI investigators and participants.

    更新日期:2020-10-01 00:00:00

  • Risk factors for prolonged duration of mechanical ventilation in acute traumatic tetraplegic patients--a retrospective cohort study.

    abstract:PURPOSE:Respiratory complications constitute an important determinant of length of stay in tetraplegic patients. In a population of tetraplegic patients, we investigated the factors involved in the duration of mechanical ventilation (MV) and whether the duration of MV was associated with the long-term neurologic status...

    journal_title:Journal of critical care

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jcrc.2013.11.021

    authors: Roquilly A,Seguin P,Mimoz O,Feuillet F,Rosenczweig E,Chevalier F,Loutrel O,Malledant Y,Sebille V,Asehnoune K,ATLANREA Study Group.

    更新日期:2014-04-01 00:00:00

  • Swallowing dysfunction in elderly trauma patients.

    abstract:PURPOSE:Newly diagnosed swallowing dysfunction is rare, with an incidence <1% in hospitalized patients. The purpose of this study was to evaluate the incidence and clinical characteristics of dysphagia in elderly trauma patients specifically. METHODS:Patients ≥75years who had newly diagnosed swallowing dysfunction wer...

    journal_title:Journal of critical care

    pub_type: 杂志文章

    doi:10.1016/j.jcrc.2017.07.027

    authors: Laan DV,Pandian TK,Jenkins DH,Kim BD,Morris DS

    更新日期:2017-12-01 00:00:00