Abstract:
PURPOSE:Respiratory complications constitute an important determinant of length of stay in tetraplegic patients. In a population of tetraplegic patients, we investigated the factors involved in the duration of mechanical ventilation (MV) and whether the duration of MV was associated with the long-term neurologic status. MATERIAL AND METHODS:In a retrospective study in 3 intensive care units (ICUs) (January 2001 to December 2009), consecutive patients (≥ 18 years) hospitalized for acute (≤ 24 hours) traumatic tetraplegia were included in the study. Patients with severe brain injury or who died in the first 48 hours were excluded. The primary outcome was the duration of MV. The secondary outcomes were the American Spinal Injury Association (ASIA) motor score on ICU discharge and at 1 year. RESULTS:A total of 164 consecutive adult patients with tetraplegia were analyzed. Median (interquartile range) ASIA motor scores were 15 (6-26) on admission, 22 (9-40) on ICU discharge (n = 145 survivors), and 37 (10-80) at 1 year (n = 52 complete follow-up). The median duration of MV was 11 (2-26) days. In multivariate analysis, MV duration increased with pneumonia (P < .0001), atelectasis (P = .0042), and tracheotomy (P < .0001). In exploratory analysis, an increased duration of MV was the only factor associated in multivariate analysis with a low ASIA motor score on ICU discharge (P = .0201) and at 1 year (P = .0003). CONCLUSIONS:Prevention of pneumonia and atelectasis is critical for the reduction of MV in tetraplegic patients. Prolonged MV was independently associated with poor neurologic status.
journal_name
J Crit Carejournal_title
Journal of critical careauthors
Roquilly A,Seguin P,Mimoz O,Feuillet F,Rosenczweig E,Chevalier F,Loutrel O,Malledant Y,Sebille V,Asehnoune K,ATLANREA Study Group.doi
10.1016/j.jcrc.2013.11.021subject
Has Abstractpub_date
2014-04-01 00:00:00pages
313.e7-13issue
2eissn
0883-9441issn
1557-8615pii
S0883-9441(13)00458-9journal_volume
29pub_type
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