Core temperature variation is associated with heart rate variability independent of cardiac index: a study of 278 trauma patients.

Abstract:

PURPOSE:The purpose of this study is to determine if temperature extremes are associated with reduced heart rate variability (HRV) and "cardiac uncoupling." MATERIALS AND METHODS:This was a retrospective, observational cohort study performed on 278 trauma intensive care unit admissions that had continuous HR, cardiac index (CI), and core temperature data from "thermodilution" Swan-Ganz catheter. Dense (captured second-by-second) physiologic data were divided into 5-minute intervals (N = 136 133; 11 344 hours of data). Mean CI, mean temperature, and integer HR SD were computed for each interval. Critically low HRV was defined as HR SD from 0.3 to 0.6 beats per minute. Temperature extremes were defined as less than 36°C or greater than 39°C. RESULTS:Low HRV and CI vary with temperature. Temperature extremes are associated with increased risk for critically low HRV (odds ratio, >1.8). Cardiac index increases with temperature until hyperthermia (>40°C). At temperature extremes, changes in CI were not explained solely by changes in HR. CONCLUSIONS:The conclusions of this study are (1) temperature extremes are associated with low HRV, potentially reflecting cardiac autonomic dysfunction; (2) CI increases with temperature; and (3) HRV provides additional physiologic information unobtainable via current invasive cardiac monitoring and current vital signs.

journal_name

J Crit Care

journal_title

Journal of critical care

authors

Mowery NT,Morris JA Jr,Jenkins JM,Ozdas A,Norris PR

doi

10.1016/j.jcrc.2010.11.008

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

534.e9-534.e17

issue

5

eissn

0883-9441

issn

1557-8615

pii

S0883-9441(10)00336-9

journal_volume

26

pub_type

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