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Predictive value of programmed ventricular stimulation after catheter ablation of post-infarction ventricular tachycardia.

Abstract：

BACKGROUND:A recent meta-analysis demonstrated a survival benefit in post-infarction patients whose ventricular tachycardia (VT) was rendered noninducible by catheter ablation. Furthermore, patients with noninducible VT had a lower VT recurrence rate than did patients whose VT remained inducible after ablation. OBJECTIVES:The purpose of this multicenter cohort study was to assess whether noninducibility after VT ablation is independently associated with improved survival. METHODS:Data from 1,064 patients who underwent VT ablation for post-infarction VT at seven international centers were analyzed. The ablation procedure was considered successful if no VT was inducible at the end of the procedure and unsuccessful if VT remained inducible or if programmed stimulation was not performed at the end of the ablation. RESULTS:Median follow-up time was 633 days. Noninducibility was independently associated with lower mortality (adjusted hazard ratio: 0.65; 95% confidence interval: 0.53 to 0.79; p<0.001). Atrial fibrillation, diabetes, and age were other independent predictors of higher mortality. Ablation of only the clinical VT in patients who also had inducible, nonclinical VTs was not associated with improved survival. CONCLUSIONS:Noninducibility after VT ablation in patients with post-infarction VT is independently associated with lower mortality during long-term follow-up.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Yokokawa M,Kim HM,Baser K,Stevenson W,Nagashima K,Della Bella P,Vergara P,Hindricks G,Arya A,Zeppenfeld K,de Riva Silva M,Daoud EG,Kumar S,Kuck KH,Tilz R,Mathew S,Ghanbari H,Latchamsetty R,Morady F,Bogun FM

doi

10.1016/j.jacc.2015.02.058

subject

Has Abstract

pub_date

2015-05-12 00:00:00

pages

1954-9

issue

18

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(15)00910-9

journal_volume

65

pub_type

杂志文章,多中心研究

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