The human counterpart of mouse B-1 cells.

abstract：:As studied by single cell RT-PCR of pituitary hormones, we demonstrated that the pituitaries of rats and mice contain a subpopulation of cells that express two or more hormone phenotypes typically belonging to lineages that are branched separately early during embryonic development, such as glycoprotein hormone alpha-...

journal_title：Annals of the New York Academy of Sciences

authors： Denef C,Pals K,Hauspie A,Vankelecom H,Seuntjens E

更新日期：2005-04-01 00:00:00

abstract：:We have presented evidence indicating that P2-purinergic receptors may activate the polyphosphoinositide-phospholipase C in HL60 cells via the mediation of a pertussis-toxin-sensitive GTP-binding protein, which also mediates the actions of chemotactic peptide receptors in these and other phagocytic white blood cells. ...

journal_title：Annals of the New York Academy of Sciences

authors： Dubyak GR,Cowen DS,Lazarus HM

更新日期：1988-01-01 00:00:00

abstract：:Neuropsychiatric disorders (i.e., mood disorders and schizophrenia) and inflammation are closely intertwined, and possibly powering each other in a bidirectional loop. Depression facilitates inflammatory reactions and inflammation promotes depression and other neuropsychiatric disorders. Patients with neuropsychiatric...

journal_title：Annals of the New York Academy of Sciences

authors： Bauer ME,Teixeira AL

更新日期：2019-02-01 00:00:00

abstract：:Here, we analyzed four population-based demographic and health surveys conducted in Bolivia between 1998 and 2016 to understand trends in anemia in children from 6 to 59 months of age by selected sociodemographic characteristics and three categories of altitude: low, medium, and high. Over the 18-year period, the prev...

journal_title：Annals of the New York Academy of Sciences

authors： Cordero D,Aguilar AM,Casanovas C,Vargas E,Lutter CK

更新日期：2019-08-01 00:00:00

abstract：:Musical enculturation is a complex, multifaceted process that includes the development of perceptual processing specialized for the pitch and rhythmic structures of the musical system in the culture, understanding of esthetic and expressive norms, and learning the pragmatic uses of music in different social situations...

journal_title：Annals of the New York Academy of Sciences

authors： Trainor LJ,Marie C,Gerry D,Whiskin E,Unrau A

更新日期：2012-04-01 00:00:00

abstract：:Force and shortening in striated muscle are driven by a structural working stroke in the globular portion of the myosin molecules-the myosin head-that cross-links the myosin-containing filaments and the actin-containing filaments. We use time-resolved X-ray diffraction in single fibers from frog skeletal muscle to lin...

journal_title：Annals of the New York Academy of Sciences

authors： Reconditi M,Linari M,Lucii L,Stewart A,Sun YB,Narayanan T,Irving T,Piazzesi G,Irving M,Lombardi V

更新日期：2005-06-01 00:00:00

abstract：:Most risk assessments assume uncertainty may be decomposed into variability and incertitude. Language is often overlooked as a source of uncertainty, but linguistic uncertainty may be pervasive in workshops, committees, and other face-to-face language-based settings where it can result in misunderstanding and arbitrar...

journal_title：Annals of the New York Academy of Sciences

authors： Carey JM,Burgman MA

更新日期：2008-04-01 00:00:00

abstract：:Murine schistosomiasis mansoni is a parasitic disease in which flukes living in the portal vein of the host produce ova that deposit in the liver and intestines. In these organs, ova release antigens that induce chronic, focal granulomatous inflammation. IFN-gamma is an inflammatory cytokine important in macrophage ac...

journal_title：Annals of the New York Academy of Sciences

authors： Weinstock JV,Elliott D

更新日期：1998-05-01 00:00:00

abstract：:Motivation can be defined as a class of central nervous processes determining the likelihood of display of a behavior and the intensity of the behavior if displayed. All behavior is, according to this definition, caused and controlled by motivation. Although the concept of motivation eventually could be replaced by an...

journal_title：Annals of the New York Academy of Sciences

authors： Hernández-González M,Guevara MA,Agmo A

更新日期：2008-01-01 00:00:00

abstract：:Loss of sympathetic nerve fibers (SNFs) occurs in inflamed tissue; and select semaphorins, upregulated during inflammation, stimulate repulsion/loss of SNFs. However, it is unknown whether other factors released locally in inflamed tissue, such as norepinephrine, dopamine, and 17β-estradiol, are also repellent. In ord...

journal_title：Annals of the New York Academy of Sciences

authors： Klatt S,Fassold A,Straub RH

更新日期：2012-07-01 00:00:00

abstract：:MRI assessment of myocardial iron and function has revolutionized the treatment of thalassemia major patients. While knowledge of somatic iron stores is vital for iron chelation management, it does not adequately monitor cardiac risk. MRI monitoring of cardiac T2* allows preclinical recognition of myocardial iron, str...

journal_title：Annals of the New York Academy of Sciences

authors： Wood JC,Noetzli L

更新日期：2010-08-01 00:00:00

abstract：:N. gonorrhoeae initiates infection by adhering to and invading columnar epithelial cells. Over time these activities often induce inflammation, with the influx of neutrophils and serum into the urethral lumen, cervical os, conjunctiva, and the like. At least some of these infected niches contain CMP-NANA (cytidine mon...

journal_title：Annals of the New York Academy of Sciences

authors： Rest RF,Liu J,Talukdar R,Frangipane JV,Simon D

更新日期：1994-08-15 00:00:00

abstract：:One in 12 people worldwide suffers from diabetes and more than 90% of affected adult individuals are diagnosed with type 2 diabetes mellitus (T2DM). Obesity adds to the personal risk to develop T2DM, and both metabolic diseases are rampantly increasing worldwide. Over recent years, primary cilia have moved into the fo...

journal_title：Annals of the New York Academy of Sciences

authors： Volta F,Gerdes JM

更新日期：2017-03-01 00:00:00

abstract：:The Hsp70 chaperone is arguably the most studied member of the heat shock protein family, a legacy traced back to the early days of phage genetics. However, much still remains to be learned about this essential protein-folding machine. Its involvement in a number of human pathologies, ranging from cancer to protein ag...

journal_title：Annals of the New York Academy of Sciences

authors： Morano KA

更新日期：2007-10-01 00:00:00

abstract：:The research presented at this conference, including a series of excellent posters from junior investigators, documents the pervasive importance of affiliation and other social behaviors. Affiliative behaviors interact with, but are distinct from reproductive and aggressive behaviors. Patterns of social behaviors tend...

journal_title：Annals of the New York Academy of Sciences

authors： Carter CS,Lederhendler I,Kirkpatrick B

更新日期：1997-01-15 00:00:00

abstract：:The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the relationship between stem cells, cancer, and the esophagus; the behavior of esophageal stem cells; and the role of genetics and epigenetics in approaches to translational research. ...

journal_title：Annals of the New York Academy of Sciences

authors： Croagh D,Frede J,Jones PH,Kaur P,Partensky C,Phillips WA

更新日期：2014-09-01 00:00:00

abstract：:Azathioprine may be tried for treatment of severe myasthenia gravis, in a dose of 2 mg/kg BW. With careful monitoring the side reactions may be controlled. The therapeutic response will occur after a time delay of 4-8 months. About one-third of patients with type II MG (severe, late onset, HLA B8-) will proceed to a c...

journal_title：Annals of the New York Academy of Sciences

authors： Matell G

更新日期：1987-01-01 00:00:00

abstract：:The molecular architecture of biological systems is heavily influenced by the highly polar interactions of water. Thus, macromolecules such as proteins that are highly water soluble must be electrically polar. Energy generation methods needed to support cell metabolic processes depend on compartmentalizing mobile ions...

journal_title：Annals of the New York Academy of Sciences

authors： Lee RC

更新日期：2005-12-01 00:00:00

abstract：:This review aims to discuss the neurophysiology of the esophagus and new methods to assess esophageal nociception. Pain and other symptoms can be caused by diseases in the mucosa or muscular or sphincter dysfunction, together with abnormal pain processing, either in the peripheral or central nervous systems. Therefore...

journal_title：Annals of the New York Academy of Sciences

authors： Brock C,McCallum RW,Gyawali CP,Farmer AD,Frøkjaer JB,McMahon BP,Drewes AM

更新日期：2016-09-01 00:00:00

abstract：:In thalassemia, iron overload is the joint outcome of excessive iron absorption and transfusional siderosis. While iron absorption is limited by a physiologic ceiling of about 3 mg/d, plasma iron turnover in thalassemia may be 10 to 15 times normal, caused by the wasteful, ineffective erythropoiesis of an enormously e...

journal_title：Annals of the New York Academy of Sciences

authors： Hershko C,Link G,Cabantchik I

更新日期：1998-06-30 00:00:00

abstract：:We examined the role of I1-imidazoline (I1-IR) receptors in control of airway function, by testing the effects of systemic administration of the I1-IR agonist moxonidine on reflex responses of tracheal smooth muscle (TSM) tone to either lung deflation or mechanical stimulation of intrapulmonary rapidly adapting recept...

journal_title：Annals of the New York Academy of Sciences

authors： Haxhiu MA,Dreshaj IA,McFadden CB,Erokwu BO,Ernsberger P

更新日期：1999-06-21 00:00:00

abstract：:Morphogenesis in the animal kingdom is closely coupled with the intracellular synthesis and the extracellular deposition of collagen. These morphogenetically important events involve multiple steps which begin in compartments inside the cell and continue in compartments outside the cell. The movement of matrix compone...

journal_title：Annals of the New York Academy of Sciences

authors： Birk DE,Trelstad RL

更新日期：1985-01-01 00:00:00

abstract：:Cytokines are powerful mediators of biologic responses in the CNS and may contribute to cellular injury in pathophysiologic states. In order to better understand the actions of cytokines in the intact mammalian CNS, a transgenic approach was employed that targeted the expression of different cytokines to astrocytes in...

journal_title：Annals of the New York Academy of Sciences

authors： Campbell IL

更新日期：1998-05-01 00:00:00

abstract：:One of the most remarkable aspects of the immune system is its ability to fashion an immune response most appropriate to the activating stimulus. Although the immune system possesses a number of adaptations to accomplish this, an important theme is local immune regulation by site-specific expression of receptors and l...

journal_title：Annals of the New York Academy of Sciences

authors： Shao L,Allez M,Park MS,Mayer L

更新日期：2006-08-01 00:00:00

abstract：:Thus, it can be shown that highly theoretical experiments carried out to evaluate the electrochemistry of thrombosis can also be shown to have significance in the generation of new products, which relates the scientific findings to successful modern prosthesis and medically useful devices. ...

journal_title：Annals of the New York Academy of Sciences

authors： Sawyer PN

更新日期：1983-01-01 00:00:00

abstract：:3-Nitropropionic acid (3-NPA) is a model mitochondrial inhibitor that causes selective neurodegeneration in brain. 3-NPA-induced neurodegeneration occurs via a secondary neurotoxicity, caused initially by ATP depletion and redox changes in the cell. It is known that the hippocampal degeneration caused by mitochondrial...

journal_title：Annals of the New York Academy of Sciences

authors： Przybyla-Zawislak BD,Thorn BT,Ali SF,Dennis RA,Amato A,Virmani A,Binienda ZK

更新日期：2005-08-01 00:00:00

abstract：:In the history of science, technical advances often precede periods of rapid accumulation of knowledge. Within the past three decades, discoveries that enabled the noninvasive measurement of the psychobiology of stress (in saliva) have added new dimensions to the study of health and human development. This widespread ...

journal_title：Annals of the New York Academy of Sciences

authors： Granger DA,Kivlighan KT,el-Sheikh M,Gordis EB,Stroud LR

更新日期：2007-03-01 00:00:00

abstract：:Two types of mixed matrix membranes were developed by UOP in the late 1980s. The first type includes adsorbent polymers, such as silicalite-cellulose acetate (CA), NaX-CA, and AgX-CA mixed matrix membranes. The silicalite-CA has a CO(2)/H(2) selectivity of 5.15 +/- 2.2. In contrast, the CA membrane has a CO(2)/H(2) se...

journal_title：Annals of the New York Academy of Sciences

authors： Kulprathipanja S

更新日期：2003-03-01 00:00:00

abstract：:After a complete spinal cord injury (SCI) at the lowest thoracic level (T13), adult cats trained to walk on a treadmill can recover hindlimb locomotion within 2-3 weeks, resulting from the activity of a spinal circuitry termed the central pattern generator (CPG). The role of this spinal circuitry in the recovery of lo...

journal_title：Annals of the New York Academy of Sciences

authors： Martinez M,Rossignol S

更新日期：2013-03-01 00:00:00

abstract：:New data on the organization of the intra-amygdaloid circuit is reviewed, beginning with the basolateral (BL) complex, the main input station of the amygdala for sensory afferents, and concluding with the central (CE) nucleus, an important source of projections to brain-stem structures mediating fear responses. The BL...

journal_title：Annals of the New York Academy of Sciences

authors： Paré D,Royer S,Smith Y,Lang EJ

更新日期：2003-04-01 00:00:00