TSG (2,3,5,4'-Tetrahydroxystilbene-2-O- β -D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans.

abstract：:In an attempt to better understand the pathogen-host interaction between invading Mycoplasma ovipneumoniae (M. ovipneumoniae) and sheep airway epithelial cells, biological effects and possible molecular mechanism of capsular polysaccharide of M. ovipneumoniae (CPS) in the induction of cell apoptosis were explored usin...

journal_title：Oxidative medicine and cellular longevity

authors： Jiang Z,Song F,Li Y,Xue D,Zhao N,Zhang J,Deng G,Li M,Liu X,Wang Y

更新日期：2017-01-01 00:00:00

abstract：:The prodrug potential of Mahonia aquifolium, a plant used for centuries in traditional medicine, recently gained visibility in the literature, and the activity of several active compounds isolated from its extracts was studied on biologic systems in vitro and in vivo. Whereas the antioxidative and antitumor activities...

journal_title：Oxidative medicine and cellular longevity

authors： Andreicuț AD,Fischer-Fodor E,Pârvu AE,Ţigu AB,Cenariu M,Pârvu M,Cătoi FA,Irimie A

更新日期：2019-12-14 00:00:00

abstract：:Neural stem/progenitor cells (NSPCs) are self-renewing, multipotent cells located in the embryonic and adult central nervous system (CNS). Extensive preclinical and clinical studies have shed light on the potential of stem cell replacement therapy for various neurodegenerative diseases. The key prerequisite for the su...

journal_title：Oxidative medicine and cellular longevity

authors： Kang M,Cho JH,Kim TJ,Lee SM,Kim HJ,Coronado I,Yi DK,Kim DY

更新日期：2020-04-25 00:00:00

abstract：Background:Liver transplantation leads to liver ischemia/reperfusion (I/R) injury, resulting in early graft dysfunction and failure. Exacerbations of oxidative stress and inflammatory response are key processes in the development of liver I/R injury. Intravenous anesthetic propofol potent effects on free radical scaven...

journal_title：Oxidative medicine and cellular longevity

authors： Yao W,Han X,Zhang Y,Guan J,Ge M,Chen C,Wu S,Chen J,Luo G,Huang P,Hei Z

更新日期：2018-10-28 00:00:00

abstract：:Barley grass powder is the best functional food that provides nutrition and eliminates toxins from cells in human beings; however, its functional ingredients have played an important role as health benefit. In order to better cognize the preventive and therapeutic role of barley grass for chronic diseases, we carried ...

journal_title：Oxidative medicine and cellular longevity

authors： Zeng Y,Pu X,Yang J,Du J,Yang X,Li X,Li L,Zhou Y,Yang T

更新日期：2018-04-04 00:00:00

abstract：:Quercetin is a flavonoid widely studied as a chemopreventive agent in different types of cancer. Previously, we reported that quercetin has a chemopreventive effect on the liver-induced preneoplastic lesions in rats. Here, we evaluated if quercetin was able not only to prevent but also to reverse rat liver preneoplast...

journal_title：Oxidative medicine and cellular longevity

authors： Carrasco-Torres G,Monroy-Ramírez HC,Martínez-Guerra AA,Baltiérrez-Hoyos R,Romero-Tlalolini MLÁ,Villa-Treviño S,Sánchez-Chino X,Vásquez-Garzón VR

更新日期：2017-01-01 00:00:00

abstract：Background:Obesity is a growing epidemic with limited effective treatments and an important risk factor for several diseases such as metabolic syndrome (MetS). In this study, we aimed to investigate the effect of 3-amino-1,2,4-triazole (ATZ), an inhibitor of catalase and heme synthesis, in a murine model for MetS. Met...

journal_title：Oxidative medicine and cellular longevity

authors： Nunes-Souza V,Dias-Júnior NM,Eleutério-Silva MA,Ferreira-Neves VP,Moura FA,Alenina N,Bader M,Rabelo LA

更新日期：2020-04-13 00:00:00

abstract：:The skin covers the outer surface of the body, so the epidermal keratinocytes within it are susceptible to reactive oxygen species (ROS) generated by environmental pollutants such as benzo(a)pyrene (BaP), a potent activator of aryl hydrocarbon receptor (AHR). Antioxidant activity is generally mediated by the nuclear f...

journal_title：Oxidative medicine and cellular longevity

authors： Fuyuno Y,Uchi H,Yasumatsu M,Morino-Koga S,Tanaka Y,Mitoma C,Furue M

更新日期：2018-02-14 00:00:00

abstract：:Recent studies have found that propofol may protect brain from cerebral ischemic-reperfusion injury. However, the underlying mechanism remains unclear. The effects of propofol were evaluated in HBVSMC after hypoxia/reoxygenation (H/R). Cell viability and levels of SOD, LDH, and MDA were measured. Apoptosis was detecte...

journal_title：Oxidative medicine and cellular longevity

authors： Zhang J,Xia Y,Xu Z,Deng X

更新日期：2016-01-01 00:00:00

abstract：:Oxidative stress has been proven as one of the most critical regulatory mechanisms involved in fine Particulate Matter- (PM2.5-) mediated toxicity. For a better understanding of the underlying mechanisms that enable oxidative stress to participate in PM2.5-induced toxic effects, the current study explored the effects ...

journal_title：Oxidative medicine and cellular longevity

authors： Zhao Y,Jin L,Chi Y,Yang J,Zhen Q,Wu H

更新日期：2019-12-07 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/3027109.]. ...

journal_title：Oxidative medicine and cellular longevity

authors： Nawrocka D,Kornicka K,Szydlarska J,Marycz K

更新日期：2017-01-01 00:00:00

abstract：:Systemic inflammation often induces neuroinflammation and disrupts neural functions, ultimately causing cognitive impairment. Furthermore, neuronal inflammation is the key cause of many neurological conditions. It is particularly important to develop effective neuroprotectants to prevent and control inflammatory brain...

journal_title：Oxidative medicine and cellular longevity

authors： Li Y,Liu T,Li Y,Han D,Hong J,Yang N,He J,Peng R,Mi X,Kuang C,Zhou Y,Han Y,Shi C,Li Z,Guo X

更新日期：2020-09-22 00:00:00

abstract：:Xanthine oxidoreductase (XOR) is the enzyme that catalyzes the oxidation of hypoxanthine to xanthine and xanthine to uric acid and is widely distributed among species. In addition to this housekeeping function, mammalian XOR is a physiological source of superoxide ion, hydrogen peroxide, and nitric oxide, which can fu...

journal_title：Oxidative medicine and cellular longevity

authors： Battelli MG,Polito L,Bortolotti M,Bolognesi A

更新日期：2016-01-01 00:00:00

abstract：:We have demonstrated that grape seed proanthocyanidins (GSPs) could effectively scavenge hydroxyl radical (•OH) in a dose-dependent manner. Since most of the ionizing radiation- (IR-) induced injuries were caused by •OH, this study was to investigate whether GSPs would mitigate IR-induced injuries in vitro and in vivo...

journal_title：Oxidative medicine and cellular longevity

authors： Huang Y,Zhao H,Cao K,Sun D,Yang Y,Liu C,Cui J,Cheng Y,Li B,Cai J,Gao F

更新日期：2016-01-01 00:00:00

abstract：:Since both O-GlcNAcylation and autophagy sense intracellular nutrient level, the alteration of those two pathways plays substantial roles in the progression of heart failure. Hence, determining the relationship between O-GlcNAcylation and autophagy is imperative to understand, prevent, and treat heart failure. However...

journal_title：Oxidative medicine and cellular longevity

authors： Yu H,Wen L,Mu Y

更新日期：2020-08-11 00:00:00

abstract：:Neutrophils play a critical role in the initiation and maintenance of intestinal inflammation. However, conventional neutrophil-targeted therapies can impair normal host defense. Tanshinone IIA has been recently revealed to act directly on neutrophils. Hence, we aimed at investigating whether Tanshinone IIA can protec...

journal_title：Oxidative medicine and cellular longevity

authors： Liu X,He H,Huang T,Lei Z,Liu F,An G,Wen T

更新日期：2016-01-01 00:00:00

abstract：:Inflammation and oxidative stress are pivotal mechanisms for the pathogenesis of ischemia and reperfusion injury (IRI). Vagus nerve stimulation (VNS) may participate in maintaining oxidative homeostasis and response to external stimulus or injury. We investigated whether the in vivo VNS can protect the liver from IRI....

journal_title：Oxidative medicine and cellular longevity

authors： Xia H,Liu Z,Liang W,Zeng X,Yang Y,Chen P,Zhong Z,Ye Q

更新日期：2020-01-21 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/6838921.]. ...

journal_title：Oxidative medicine and cellular longevity

authors： Songia P,Porro B,Chiesa M,Myasoedova V,Alamanni F,Tremoli E,Poggio P

更新日期：2017-01-01 00:00:00

abstract：:Fermented papaya extracts (FPEs) are obtained by fermentation of papaya by Aspergillus oryzae and yeasts. In this study, we investigated the protective effects of FPEs on mammary gland hyperplasia induced by estrogen and progestogen. Rats were randomly divided into 6 groups, including a control group, an FPE-alone gro...

journal_title：Oxidative medicine and cellular longevity

authors： You Z,Sun J,Xie F,Chen Z,Zhang S,Chen H,Liu F,Li L,Chen G,Song Y,Xuan Y,Zheng G,Xin Y

更新日期：2017-01-01 00:00:00

abstract：:We have focused on determining the range of oxidative stress biomarkers and their dynamic changes in patients at different time points after the acute ischemic stroke (AIS). 82 patients with AIS were involved in our study and were tested: within 24 h from the onset of the attack (group A); at 7-day follow-up (group B)...

journal_title：Oxidative medicine and cellular longevity

authors： Žitňanová I,Šiarnik P,Kollár B,Chomová M,Pazderová P,Andrezálová L,Ježovičová M,Koňariková K,Laubertová L,Krivošíková Z,Slezáková L,Turčáni P

更新日期：2016-01-01 00:00:00

abstract：Background:Mitochondrial dynamics (mtDYN) has been proposed as a bridge between mitochondrial dysfunction and insulin resistance (IR), which is involved in the pathogenesis of type 2 diabetes (T2D). Our previous study has identified that mitochondrial DNA (mtDNA) haplogroup B4 is a T2D-susceptible genotype. Using trans...

journal_title：Oxidative medicine and cellular longevity

authors： Lin HY,Weng SW,Chang YH,Su YJ,Chang CM,Tsai CJ,Shen FC,Chuang JH,Lin TK,Liou CW,Lin CY,Wang PW

更新日期：2018-09-30 00:00:00

abstract：:Ischemia-reperfusion (I/R) injury caused by acute myocardial infarction (AMI) can initiate a strong inflammatory response. Polymorphonuclear cells (PMNs) are the most important inflammatory cells. Our previous studies found that the calcium-sensing receptor (CaSR) regulates the proinflammatory effects of PMNs. However...

journal_title：Oxidative medicine and cellular longevity

authors： Zhai TY,Cui BH,Zhou Y,Xu XY,Zou L,Lin X,Zhu XS,Zhang SW,Xie WL,Cheng YY,Sun YH

更新日期：2021-01-12 00:00:00

abstract：:Doxorubicin (DOX) is a broad-spectrum antitumor drug while its use is limited due to its neurobiological side effects associated with depression. We investigated the neuroprotective efficacy of dl-3-n-butylphthalide (dl-NBP) against DOX-induced anxiety- and depression-like behaviors in rats. dl-NBP was given (30 mg/kg...

journal_title：Oxidative medicine and cellular longevity

authors： Liao D,Xiang D,Dang R,Xu P,Wang J,Han W,Fu Y,Yao D,Cao L,Jiang P

更新日期：2018-08-16 00:00:00

abstract：:Surgical intervention is currently the only option for an abdominal aortic aneurysm (AAA), preventing its rupture and sudden death of a patient. Therefore, it is crucial to determine the pathogenic mechanisms of this disease for the development of effective pharmacological therapies. Oxidative stress is said to be one...

journal_title：Oxidative medicine and cellular longevity

authors： Kopacz A,Werner E,Grochot-Przęczek A,Klóska D,Hajduk K,Neumayer C,Józkowicz A,Piechota-Polanczyk A

更新日期：2020-06-16 00:00:00

abstract：:This study aimed to elucidate the determinants of higher plasma malondialdehyde (MDA) in free-living adults. In a cross-sectional study we evaluated 148 free-living subjects (54 ± 11 years, 78% women) at high risk for or with metabolic syndrome (MetS). They were assessed by anthropometry and body composition, dietary ...

journal_title：Oxidative medicine and cellular longevity

authors： Moreto F,de Oliveira EP,Manda RM,Burini RC

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this study was to investigate the modulation of histone deacetylase 2 (HDAC2) on mitochondrial apoptosis in acute liver failure (ALF). The cellular model was established with LO2 cells stimulated by tumor necrosis factor alpha (TNF-α)/D-galactosamine (D-gal). Rats were administrated by lipopolysaccharid...

journal_title：Oxidative medicine and cellular longevity

authors： Wang Y,Yang F,Jiao FZ,Chen Q,Zhang WB,Wang LW,Gong ZJ

更新日期：2019-04-28 00:00:00

abstract：:Hyperthyroidism is an endocrine disorder characterized by excessive secretion of thyroid hormones T3 and T4. Thyroid hormones exert pleiotropic actions on numerous tissues and induce an overall increase in metabolism, with an increase in energy demand and oxygen consumption. Therefore, the purpose of this study was to...

journal_title：Oxidative medicine and cellular longevity

authors： Costilla M,Macri Delbono R,Klecha A,Cremaschi GA,Barreiro Arcos ML

更新日期：2019-06-02 00:00:00

abstract：:Accumulation of advanced glycation end products (AGEs) contributes to ageing and age-related diseases, especially type 2 diabetes. The NLRP3 inflammasome, as a vital component of the innate immune system, is implicated in the pathogenesis of type 2 diabetes. However, the role of the NLRP3 inflammasome in AGE-induced p...

journal_title：Oxidative medicine and cellular longevity

authors： Kong X,Lu AL,Yao XM,Hua Q,Li XY,Qin L,Zhang HM,Meng GX,Su Q

更新日期：2017-01-01 00:00:00

abstract：:Intracellular reactive apoptosis and reactive oxygen species (ROS) play a crucial role in ultraviolet- (UV-) induced inflammation and aging reaction in human dermal tissues. This study determines the mechanism by which Haematococcus pluvialis extracts (HPE) and purified astaxanthin (HPA) to promote skin regeneration i...

journal_title：Oxidative medicine and cellular longevity

authors： Chou HY,Ma DL,Leung CH,Chiu CC,Hour TC,Wang HD

更新日期：2020-08-03 00:00:00

abstract：:Serine-threonine kinase receptor-associated protein (STRAP) is a transforming growth factor β (TGF-β) receptor-interacting protein that has been implicated in both cell proliferation and cell death in response to various stresses. However, the precise roles of STRAP in these cellular processes are still unclear. The m...

journal_title：Oxidative medicine and cellular longevity

authors： Manoharan R,Seong HA,Ha H

更新日期：2018-04-19 00:00:00