Clinical value of black-blood high-resolution magnetic resonance imaging for intracranial atherosclerotic plaques.

abstract：:Delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) is a serious complication that occurs several days or weeks after carbon monoxide (CO) intoxication. This study identified computed tomography (CT) findings in the prediction of DEACMP development. Adults with CO poisoning admitted to Beijing Chaoya...

journal_title：Experimental and therapeutic medicine

authors： Du X,Gu H,Hao F,Gao L,Wang J,Sun C,Zhang H,Ma P,Zhang X,Hu W

更新日期：2019-04-01 00:00:00

abstract：:Primary lung enteric adenocarcinoma is a rare type of invasive lung carcinoma. Its morphology and immunohistochemistry are those of colorectal carcinoma, but there is no associated primary colorectal carcinoma. The present study describes the case of a 53-year-old female who presented with an irritating cough and a ma...

journal_title：Experimental and therapeutic medicine

authors： Lin LI,Xu CW,Zhang BO,Liu RR,Ge FJ,Zhao CH,Jia RU,Qin QH,Stojsic J,Wang Y,Xu JM

更新日期：2016-01-01 00:00:00

abstract：:This study aimed to analyze the correlation between single nucleotide polymorphisms (SNPs) of the actin, aortic smooth muscle (ACTA2) gene and coronary artery stenosis in patients with type 2 diabetes mellitus (T2DM). Eight SNPs from the promoter region of the ACTA2 gene were screened. Patients with T2DM (n=251) were ...

journal_title：Experimental and therapeutic medicine

authors： Fang H,Luo X,Wang Y,Liu N,Fu C,Wang H,Fang Y,Shi W,Zhang Y,Zeng C,Wang X

更新日期：2014-04-01 00:00:00

abstract：:This study was designed to investigate the correlation of vitamin D receptor (VDR) gene polymorphism with bronchial asthma in children. Seventy patients admitted to Daqing Longnan Hospital and diagnosed as bronchial asthma for the first time from April 2015 to May 2017 were selected as observation group. Patients rece...

journal_title：Experimental and therapeutic medicine

authors： Hou C,Zhu X,Chang X

更新日期：2018-03-01 00:00:00

abstract：:Rhubarb has been used as an evacuant for thousands of years. However, recent research has indicated that rhubarb inhibits inflammation and protects organ function. In the current study, the use of rhubarb was investigated in patients with intra-abdominal hypertension (IAH). Specifically, its dual role in attenuating l...

journal_title：Experimental and therapeutic medicine

authors： Wan B,Zhang H,Yin J,Fu H,Chen Y,Yang L,Liu D,Lv T,Song Y

更新日期：2017-07-01 00:00:00

abstract：:Many studies have found the function of nitric oxide (NO) in cancer as a pro-neoplastic vs. an anti-neoplastic effector, but the role of NO in hepatocellular carcinoma (HCC) remains unclear. The present study aimed to investigate the effects of nitric oxide (NO) on the biological behavior of the human hepatocellular c...

journal_title：Experimental and therapeutic medicine

authors： Zhou L,Zhang H,Wu J

更新日期：2016-05-01 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (ICC) is a cancer type with high malignancy and a current lack of biomarkers to predict recurrence. In the present study, to identify potential biomarkers, five ICC datasets from the Gene Expression Omnibus database were analyzed to construct initial datasets by using a robust rank aggr...

journal_title：Experimental and therapeutic medicine

authors： Chen FY,Zhou C,Zhang XY,Zhou KQ,Peng YF,Yu L,Fan J,Zhou J,Hu J,Wang Z

更新日期：2020-11-01 00:00:00

abstract：:MicroRNA (miR)-199b-5p has been reported to have a critical role in various types of malignancy. However, the exact function miR-199b-5p in renal cancer remains to be fully elucidated. The present study aimed to detect the expression levels of miR-199b-5p in renal cell carcinoma (RCC) tissues and RCC cell lines, and i...

journal_title：Experimental and therapeutic medicine

authors： Lai Y,Quan J,Lin C,Li H,Hu J,Chen P,Xu J,Guan X,Xu W,Lai Y,Ni L

更新日期：2018-07-01 00:00:00

abstract：:Cancer antigen 125 (CA125), encoded by the mucin 16 cell surface associated (MUC16) gene, has been widely used as a biomarker for ovarian cancer (OC) screening. However, it has yet to be elucidated as to why its levels increase with tumor progression as well as with certain other non-malignant conditions. Based on our...

journal_title：Experimental and therapeutic medicine

authors： Liu J,Li L,Luo N,Liu Q,Liu L,Chen D,Cheng Z,Xi X

更新日期：2021-02-01 00:00:00

abstract：:As a strategy to prevent the well-known immunosuppressant effects of cyclophosphamide (CY), the immunomodulatory activity of the polysaccharide isolated from Urtica macrorrhiza Hand.-Mazz. (UMHMPS) was investigated in the present study. The chemical properties of UMHMPS, including total carbohydrates, uronic acid, pro...

journal_title：Experimental and therapeutic medicine

authors： Wang Z,Li Y,Wang C,Xia H,Liang Y,Li Z

更新日期：2019-09-01 00:00:00

abstract：:The radiofrequency ablation (RFA) lesion size is posited to be disproportionate to the total delivered energy, and temperature-time integration (TTI) may have a more critical effect on lesion size. The present study aimed to evaluate this hypothesis by determining the temperature threshold and temperature distribution...

journal_title：Experimental and therapeutic medicine

authors： Tseng H,Lin SE,Chang YL,Chen MH,Hung SH

更新日期：2016-03-01 00:00:00

abstract：:The aim of the present study was to evaluate the expression of vascular endothelial growth factor (VEGF) and hypoxia inducible factor-1 (HIF-1), and to investigate the role of the HIF-1/VEGF signaling pathway following spinal cord injury (SCI). A total of 90 12-week-old Sprague Dawley rats were randomly divided into t...

journal_title：Experimental and therapeutic medicine

authors： Chen H,Li J,Liang S,Lin B,Peng Q,Zhao P,Cui J,Rao Y

更新日期：2017-03-01 00:00:00

abstract：:Cardiovascular ischemic disease refers to a large class of conditions that are harmful to human health. A number of previous studies have demonstrated that microRNAs (miRs) have notable roles in regulating cardiac injury. miR-144 is influential in the differentiation, growth, and metastatic processes of cells; however...

journal_title：Experimental and therapeutic medicine

authors： E L,Jiang H,Lu Z

更新日期：2019-03-01 00:00:00

abstract：:The inactivation of the cyclin-dependent kinase inhibitor p16(INK4A) gene by hypermethylation is observed in numerous types of cancer. New findings indicate that DNA and histone methylation act in concert in gene silencing. In this study, we investigated the methylation status of the p16(INK4A) gene promoter and the h...

journal_title：Experimental and therapeutic medicine

authors： Yoruker EE,Mert U,Bugra D,Yamaner S,Dalay N

更新日期：2012-11-01 00:00:00

abstract：:Oxidative stress results in damage to cellular structures and has been linked to numerous diseases, including cancer. Extracellular superoxide dismutase (EC-SOD) is a principal enzymatic antioxidant in extracellular space. The purpose of this study was to determine whether the expression of EC-SOD protein is altered i...

journal_title：Experimental and therapeutic medicine

authors： Yokoe H,Nomura H,Yamano Y,Fushimi K,Sakamoto Y,Ogawara K,Shiiba M,Bukawa H,Uzawa K,Takiguchi Y,Tanzawa H

更新日期：2010-07-01 00:00:00

abstract：:Monosialotetrahexosylganglioside sodium (GM1) is widely used in the treatment of central and peripheral neurological injuries. In addition to its neuroprotective activity, GM1 exerts protective effects on brain microvascular endothelial cells, although the mechanisms underlying these effects remain unclear. The aim of...

journal_title：Experimental and therapeutic medicine

authors： Zhao H,Li X,Li G,Sun BO,Ren L,Zhao C

更新日期：2015-09-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) has been demonstrated to affect the oxidative stress status in several in vitro, in vivo and clinical studies. The aim of the present study was to evaluate the effect of a GLP-1 analogue, exenatide, on oxidative stress parameters and apoptotic markers in testicular cells in an iron over...

journal_title：Experimental and therapeutic medicine

authors： Yesil S,Sungu N,Kilicarslan A,Kuskonmaz SM,Kara H,Kucuk A,Polat F,Kavutcu M,Arslan M

更新日期：2018-12-01 00:00:00

abstract：:Infantile neuroaxonal dystrophy (INAD) is a rare neurodegenerative disorder. Phospholipase A2 group VI (PLA2G6) gene mutations have been identified in the majority of individuals with INAD. The present case report is on a Chinese female pediatric patient (age, 18 months) diagnosed with INAD with deafness. To date, onl...

journal_title：Experimental and therapeutic medicine

authors： Wang B,Wu,Tang J

更新日期：2018-08-01 00:00:00

abstract：:Erythropoietin (EPO), a glycoprotein originally known for its important role in the stimulation of erythropoiesis, has recently been shown to have significant protective effects in animal models of kidney and intestinal ischemia-reperfusion injury (IRI). However, the mechanism underlying these protective effects remai...

journal_title：Experimental and therapeutic medicine

authors： Rong R,Xijun X

更新日期：2015-08-01 00:00:00

abstract：:It has been widely reported that the serum anion gap is significantly associated with mortality in intensive care unit (ICU); however, it remains unknown whether the association is present in aortic aneurysm (AA) patients. The present study aimed to investigate the association between the admission serum anion gap and...

journal_title：Experimental and therapeutic medicine

authors： Chen Q,Chen Q,Li L,Lin X,Chang SI,Li Y,Tian Z,Liu W,Huang K

更新日期：2018-09-01 00:00:00

abstract：:Expanded polytetrafluoroethylene (ePTFE) has been extensively used for facial soft tissue augmentation procedures, and is regarded as safe and reliable and suitable as a permanent implant. This implant is generally used in the lower third of the face for lips filling, nasal augmentation, nasolabial folds and chin augm...

journal_title：Experimental and therapeutic medicine

authors： Liu X,Zhang Y,Wang S,Lei Z,Li X,Fan D

更新日期：2016-11-01 00:00:00

abstract：:The use of intravenous dexmedetomidine during surgery has been shown to suppress inflammatory cytokines peri-operatively. It has also been demonstrated that dexmedetomidine may benefit cognitive function in elderly patients following surgery; however, it is not clear whether dexmedetomidine reduces postoperative cogni...

journal_title：Experimental and therapeutic medicine

authors： Li Y,He R,Chen S,Qu Y

更新日期：2015-11-01 00:00:00

abstract：:Curcuma longa is a plant that belongs to the ginger family, Zingiberaceae. It has been used in Siddha medicine for thousands of years in Asia. Parkinson's disease (PD) is a degenerative disorder of the central nervous system that affects the motor system of the brain. Death of dopamine-producing cells in the substanti...

journal_title：Experimental and therapeutic medicine

authors： Ma XW,Guo RY

更新日期：2017-05-01 00:00:00

abstract：:Clinical efficacy of octreotide acetate combined with thrombin in the treatment of liver cirrhosis complicated with gastrointestinal hemorrhage was investigated. A retrospective analysis of 157 patients with liver cirrhosis and gastrointestinal hemorrhage admitted to Weifang People's Hospital from March 2012 to Septem...

journal_title：Experimental and therapeutic medicine

authors： Wang X,Liu Y,Zhao J,Zhang J

更新日期：2019-05-01 00:00:00

abstract：:The aim of this study was to evaluate the safety of the continuous administration of recombinant human endostatin (Endostar) in healthy mice. A total of 16 nude mice were randomly divided into four treatment groups: a continuous administration group injected intraperitoneally (i.p.) with 14 mg/kg Endostar over seven d...

journal_title：Experimental and therapeutic medicine

authors： Huang R,Zhan Q,Zhou X,Chu Z,Jiang J,Liang X

更新日期：2012-06-01 00:00:00

abstract：:Saw palmetto extract can induce the apoptosis of prostate cancer cells. The aim of the present study was to investigate the effect of saw palmetto extract on the phosphatidylinositol 3-kinase (PI3K)/Akt signaling transduction pathway in human glioma U87 and U251 cell lines. Suspensions of U87 and U251 cells in a logar...

journal_title：Experimental and therapeutic medicine

authors： Yang Y,Hui L,Yuqin C,Jie L,Shuai H,Tiezhu Z,Wei W

更新日期：2014-08-01 00:00:00

abstract：:This study aimed to explore and evaluate the tolerability and antiviral activity of pegylated recombinant human consensus interferon-α (PEG-CIFN) in adults with hepatitis C virus (HCV) infection. A total of 48 adult subjects chronically infected with HCV were divided into five groups, which were treated separately wit...

journal_title：Experimental and therapeutic medicine

authors： Ding YH,Liu B,Zhang X,Sun L,Zhang H,Luo H,Sun YF,Liu CJ,Zhang Q,Cao YC,Chen H,Niu JQ

更新日期：2017-01-01 00:00:00

abstract：:The aim of the present study was to determine the ferulic acid (FA) content of Radix Angelicae Sinensis (AS), Danggui-Buxue-Tang (DBT) and Danggui-Sini-Tang (DST) using the same ultra performance liquid chromatography system and method. FA was eluted using an Acquity BEH C18 column (100×2.1 mm inner diameter; 1.7 μm)....

journal_title：Experimental and therapeutic medicine

authors： Yao JM,Yu LJ,Chen Q,Chen ZQ,Wang DS,Qiu XJ,Zhao LL

更新日期：2014-05-01 00:00:00

abstract：:Vascular smooth muscle cell (VSMC) accumulation and hypertrophy are common in vascular disorders, and inflammation has a crucial role in the development of these diseases. To investigate the effect of inflammation on the neurotransmission of VSMC, bioinformatic analysis was performed, following next generation sequenc...

journal_title：Experimental and therapeutic medicine

authors： Gan S,Qiu S,Feng Y,Zhang Y,Qian Q,Wan Z,Tang J

更新日期：2017-04-01 00:00:00

abstract：:The aim of this study was to detect early changes (within 1-4 h) in the brain natriuretic peptide (BNP) levels of rats with acute myocardial infarction (AMI). A total of 35 Wistar rats were established as models of AMI and 30 sham-operated rats were used as the control group. The myocardia of the two groups were obser...

journal_title：Experimental and therapeutic medicine

authors： Li J,Yin FF,Hou YL

更新日期：2013-04-01 00:00:00