The use of expanded polytetrafluoroethylene in depressed deformities of the face.

abstract：:Kidney morphology has been used to estimate renal functions. The present study investigated the usefulness of kidney length and renal parenchymal volume (RPV) measured using three-dimensional ultrasonography (3-D USG) in estimating renal pathological findings, and the outcome in patients with nephropathy who underwent...

journal_title：Experimental and therapeutic medicine

authors： Xu J,Hwang SI,Lee HJ,Chin HJ

更新日期：2018-02-01 00:00:00

abstract：:This study aimed to investigate the influence of intrathecal injection with dexmedetomidine on the behavioral ability and analgesic effects of rat models with chronic neuropathic pain. It also discusses the role that the expression of protein kinase C (PKC) in the spinal dorsal horn plays in the analgesic mechanism of...

journal_title：Experimental and therapeutic medicine

authors： Li X,Zhang W

更新日期：2018-11-01 00:00:00

abstract：:Aortic valve (AoV) stenosis is the third most common cardiovascular disease. The pathogenesis of AoV stenosis is associated with an inflammatory process where MMPs serve important roles. The aim of the present study was to determine the association between matrix metalloproteinases (MMPs), tissue inhibitors of metallo...

journal_title：Experimental and therapeutic medicine

authors： Lurins J,Lurina D,Svirskis S,Nora-Krukle Z,Tretjakovs P,Mackevics V,Lejnieks A,Rapisarda V,Baylon V

更新日期：2019-04-01 00:00:00

abstract：:Effects of paraquat (PQ) on interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in macrophages were investigated. Different concentrations of PQ were added to mouse macrophage RAW264.7 for culture. According to different concentrations of PQ, mice were divided into micro concentration (0.01 mmol/l), low concentra...

journal_title：Experimental and therapeutic medicine

authors： Huang J,Ning N,Zhang W

更新日期：2019-03-01 00:00:00

abstract：:The aim of the present study was to explore the effects and mechanisms of insulin on mitochondrial oxidative stress in septic acute kidney injury (AKI). Male Sprague Dawley rats were divided randomly into four groups: Control group, sham surgery group, cecal ligation and puncture (CLP) group, and CLP plus insulin grou...

journal_title：Experimental and therapeutic medicine

authors： Chen GD,Zhang JL,Chen YT,Zhang JX,Wang T,Zeng QY

更新日期：2018-04-01 00:00:00

abstract：:The aim of the present study was to investigate the susceptibility of two coronary artery disease (CAD)-associated single nucleotide polymorphisms on 9p21 (rs1333049 and rs10757278) to myocardial infarction (MI) in a primary (stratification of high risk group for MI) and secondary prevention setting. The prospective o...

journal_title：Experimental and therapeutic medicine

authors： Nikulina S,Artyukhov I,Shesternya P,Gavrilyuk O,Maksimov V,Voyevoda M,Brusentsov D

更新日期：2019-10-01 00:00:00

abstract：:The aim of the present study was to analyze the mechanism by which nerve growth factor (NGF) promotes callus formation in mice with tibial fracture. NGF transgenic homozygotic mice and NGF wild homozygotic mice were selected to construct non-stabilized fracture model of tibia. The mice were sacrificed on days 7, 14 an...

journal_title：Experimental and therapeutic medicine

authors： Sang XG,Wang ZY,Cheng L,Liu YH,Li YG,Qin T,Di K

更新日期：2017-04-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate the expression of targeted genes in a post-transcriptional manner. Increasing evidence indicates that miRNAs play important roles in cancer pathogenesis, including apoptosis, proliferation and differentiation, as oncogenes or tumor suppressors. Previo...

journal_title：Experimental and therapeutic medicine

authors： Shen ZY,Zhang ZZ,Liu H,Zhao EH,Cao H

更新日期：2014-06-01 00:00:00

abstract：:The aim of the present study was to determine how Endostar inhibits tumor angiogenesis and increases radiation sensitivity when combined with radiotherapy. In vitro studies were conducted to analyze the expression levels of transforming growth factor-β1 (TGF-β1), hypoxia-inducible factor 1 (HIF-1α) and basic fibroblas...

journal_title：Experimental and therapeutic medicine

authors： Wu Y,Zheng Y,Shen Z,Ge W,Xie Y,Li C

更新日期：2014-04-01 00:00:00

abstract：:The effect of hepatitis B immune globulin (HBIG) combined with hepatitis B vaccine on blocking hepatitis B virus (HBV) transmission between mother and infant and its effect on immune cells were studied. Ninety newborn infants confirmed to be HBV surface antigen (HBsAg)-positive were divided equally into three groups. ...

journal_title：Experimental and therapeutic medicine

authors： Gong J,Liu X

更新日期：2018-01-01 00:00:00

abstract：:Hypophosphatasia (HPP) is a rare hereditary systemic disease that is characterized by defective bone and/or dental mineralization, and is caused by mutations in the alkaline phosphatase gene (ALPL). The present study investigated the ALPL mutation in a Chinese Han family with HPP and studied the pathogenesis of the mu...

journal_title：Experimental and therapeutic medicine

authors： Huang H,Wang J,Liang Y,Wei X,Guo D,Sun H,Zhang X,Xu X,Xiong F

更新日期：2020-12-01 00:00:00

abstract：:Curcuma longa is a plant that belongs to the ginger family, Zingiberaceae. It has been used in Siddha medicine for thousands of years in Asia. Parkinson's disease (PD) is a degenerative disorder of the central nervous system that affects the motor system of the brain. Death of dopamine-producing cells in the substanti...

journal_title：Experimental and therapeutic medicine

authors： Ma XW,Guo RY

更新日期：2017-05-01 00:00:00

abstract：:Several molecules have been proven to be associated with responsiveness to chemotherapy. A clinical study on the expression of excision repair cross-complementing (ERCC)-1 and class III β-tubulin was conducted in advanced stage non-small cell lung cancer (NSCLC) patients. We investigated 34 resected stage III NSCLC pa...

journal_title：Experimental and therapeutic medicine

authors： Huang CL,Kadota K,Liu D,Ueno M,Nakasima N,Ishikawa S,Gotoh M,Misaki N,Chang SS,Yokomise H

更新日期：2010-05-01 00:00:00

abstract：:The aim of the present study was to screen differentially co-expressed genes and the involved transcription factors (TFs) and microRNAs (miRNAs) in venous thromboembolism (VTE). Microarray data of GSE19151 were downloaded from Gene Expression Omnibus, including 70 patients with VTE and 63 healthy controls. Principal c...

journal_title：Experimental and therapeutic medicine

authors： Ming Z,Ding W,Yuan R,Jin J,Li X

更新日期：2016-06-01 00:00:00

abstract：:The effects of atrial fibrillation on complications and prognosis of patients receiving emergency percutaneous coronary intervention after acute myocardial infarction (AMI) were investigated. Eighty AMI patients treated with interventional vascular recanalization in the Affiliated Hospital of Weifang Medical Universit...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Zhang L,Zheng H,Chen H

更新日期：2018-10-01 00:00:00

abstract：:Certain microRNAs (miRs) regulate the progression and metastasis of various cancer types. In the present study, the role of miR-370 in the progression and proliferation of human astrocytoma and glioblastoma cells was assessed and the underlying molecular mechanism was investigated. miR-370 levels in clinical specimens...

journal_title：Experimental and therapeutic medicine

authors： Lu M,Wang Y,Zhou S,Xu J,Li J,Tao R,Zhu Y

更新日期：2018-01-01 00:00:00

abstract：:Granulomatosis with polyangiitis (GPA) is a rheumatic auto-immune disease involved in vasculitis. It is rarely reported that anti-neutrophil cytoplasmic antibodies (ANCAs) associated with GPA would cause main tract stenosis. The current report documents a 54-year-old woman, with a history of severe cough, presented wi...

journal_title：Experimental and therapeutic medicine

authors： Zhou D,Zhang P,Zhang Y,Zhang Y,Zhang X,Li J,Zhou Z,Zhu N

更新日期：2020-05-01 00:00:00

abstract：:Here, we present a case of post-operative liver metastases from pancreatic head cancer in a patient with leukocytopenia, who was safely treated by hepatic arterial infusion (HAI) chemotherapy consisting of gemcitabine and 5-FU. The patient was a 61-year-old woman who underwent pancreaticoduodenectomy for pancreatic he...

journal_title：Experimental and therapeutic medicine

authors： Tajima H,Ohta T,Kitagawa H,Sakai S,Makino I,Hayashi H,Nakagawara H,Onishi I,Takamura H,Ninomiya I,Fushida S,Tani T,Fujimura T,Kayahara M,Koda W,Minami T,Ryu Y,Sanada J,Matsui O

更新日期：2010-11-01 00:00:00

abstract：:The aim of this study was to determine whether the vascular endothelial growth factor (VEGF) +936C/T polymorphism confers susceptibility to gastric cancer (GC) by conducting a meta-analysis. Publications addressing the association between the VEGF +936C/T polymorphism and GC risk were selected from the Pubmed, Embase ...

journal_title：Experimental and therapeutic medicine

authors： Zhou LP,Luan H,Dong XH,Jin GJ,Man DL,Shang H

更新日期：2011-09-01 00:00:00

abstract：:The aim of the present study was to evaluate the expression of vascular endothelial growth factor (VEGF) and hypoxia inducible factor-1 (HIF-1), and to investigate the role of the HIF-1/VEGF signaling pathway following spinal cord injury (SCI). A total of 90 12-week-old Sprague Dawley rats were randomly divided into t...

journal_title：Experimental and therapeutic medicine

authors： Chen H,Li J,Liang S,Lin B,Peng Q,Zhao P,Cui J,Rao Y

更新日期：2017-03-01 00:00:00

abstract：:Fistular onion stalk is used as a traditional herbal medicine, and its extract exhibits certain beneficial effects on cardiovascular disease. In this study, the effects of fistular onion stalk extract on the pathological features, circulating inflammatory cytokines, local renin-angiotensin-aldosterone system (RAAS) an...

journal_title：Experimental and therapeutic medicine

authors： He B,Hao J,Sheng W,Xiang Y,Zhang J,Zhu H,Tian J,Zhu X,Feng Y,Xia H

更新日期：2014-09-01 00:00:00

abstract：:Previous studies have indicated pro-tumor functions of macrophages in tumor progression in different types of malignant tumors. The detailed mechanisms of cell-cell interaction between macrophages and tumor cells have been investigated by means of in vitro co-culture experiments. The present study developed magnetite ...

journal_title：Experimental and therapeutic medicine

authors： Komohara Y,Kawauchi R,Makiyama E,Mikami K,Horlad H,Fujiwara Y,Kida T,Takeya M,Niidome T

更新日期：2017-08-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a primary malignancy in the liver, which is a global health problem. The present study aimed to observe the apoptotic effects of berbamine on SMMC-7721 cell lines and to investigate the effects of berbamine on induction of the intrinsic apoptotic pathway. The human HCC SMMC-7721 cells...

journal_title：Experimental and therapeutic medicine

authors： Cao Y,Cao J,Yu B,Wang S,Liu L,Tao L,Sun W

更新日期：2018-02-01 00:00:00

abstract：:Breast cancer remains a worldwide public-health issue. Novel drugs that increase the sensitivity and reduce the toxic side effects of chemotherapeutic agents are urgently required. The present study investigated the effect and mechanism of the short-term intermittent administration of an anticancer bioactive peptide (...

journal_title：Experimental and therapeutic medicine

authors： Li X,Gao B,Su X

更新日期：2020-09-01 00:00:00

abstract：:The present study was to analyze the mechanism of cytomembrane ATP-sensitive K+ channels (KATP) in the neurovascular unit treatment of ischemic stroke in the recovery period. A total of 24 healthy adult male Wistar rats of 5-8 weeks age, weighing 160-200 g were randomly divided into the control (sham-operation group),...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Pan S,Zheng X,Wan Q

更新日期：2016-08-01 00:00:00

abstract：:CGA-N46 is a novel antifungal peptide derived from the N-terminus of human Chromogranin A, corresponding to the 31st to 76th amino acids. Further research on its activities and characteristics may be helpful for the application of CGA-N46 in medical or other situations. In the present study, the antifungal spectrum an...

journal_title：Experimental and therapeutic medicine

authors： Li RF,Lu YL,Lu YB,Zhang HR,Huang L,Yin Y,Zhang L,Liu S,Lu Z,Sun Y

更新日期：2015-12-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy and safety of polyethylene glycol 4000 (PEG 4000) for the treatment of constipation in children over 8 years of age. A total of 216 children from 7 hospitals were enrolled. A total of 105 patients received oral PEG 4000 (20 g/day) and 111 patients received oral lactul...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Wang B,Jiang X,Jiang M,Xu C,Shao C,Jia L,Huang Z,Xu X,Liu H,Shang L

更新日期：2012-05-01 00:00:00

abstract：:Embelin is a small-molecule inhibitor extracted from plants of the Myrsinaceae family demonstrating specific inhibition of the X-linked inhibitor of apoptosis protein (XIAP) to affect the proliferation and apoptosis of various types of tumor cells. However, the mechanism of action for this effect remains unclear. The ...

journal_title：Experimental and therapeutic medicine

authors： Taghiyev A,Sun D,Gao ZM,Liang R,Wang L

更新日期：2012-10-01 00:00:00

abstract：:Obstructive sleep apnoea (OSA) is a very common sleep and breathing disorder that occurs in worldwide. It is important to develop a more effective treatment for OSA to overcome lung cell apoptosis during intermittent hypoxia (IH). A mitochondrial separation protein inhibitor (Mdivi-1) has been demonstrated to be a pow...

journal_title：Experimental and therapeutic medicine

authors： Zhao D,Yin CY,Ye XW,Wan ZF,Zhao DG,Zhang XY

更新日期：2019-03-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a progressive disorder of unknown etiology that predominantly affects the lungs, and the resulting respiratory failure can be fatal. Extrapulmonary LAM is a rare disease that often occurs concurrently with pulmonary LAM. Usually, extrapulmonary LAM presents as a localized, well-circum...

journal_title：Experimental and therapeutic medicine

authors： Fu W,Li Y,Li H,Yang P,Xing X

更新日期：2016-09-01 00:00:00