miR-199b-5p serves as a tumor suppressor in renal cell carcinoma.

abstract：:The present retrospective study aimed to investigate the prognostic factors for critically ill patients with an Acinetobacter baumannii (A. baumannii) infection. A total of 37 patients from the intensive care unit (ICU) were enrolled in the study. Data was collected from patients, including age, gender, ethnicity, A. ...

journal_title：Experimental and therapeutic medicine

authors： Xiao D,Wang L,Zhang D,Xiang D,Liu Q,Xing X

更新日期：2017-04-01 00:00:00

abstract：:Expanded polytetrafluoroethylene (ePTFE) has been extensively used for facial soft tissue augmentation procedures, and is regarded as safe and reliable and suitable as a permanent implant. This implant is generally used in the lower third of the face for lips filling, nasal augmentation, nasolabial folds and chin augm...

journal_title：Experimental and therapeutic medicine

authors： Liu X,Zhang Y,Wang S,Lei Z,Li X,Fan D

更新日期：2016-11-01 00:00:00

abstract：:Professor Alan Michael Weindling, Emeritus Professor of Perinatal Medicine at the University of Liverpool in the UK, is one of the pioneers of modern neonatal care worldwide with an enormous contribution to the care of premature babies in the city of Liverpool. During the last 3 decades, his contributions focused on t...

journal_title：Experimental and therapeutic medicine

authors： Mammas IN,Spandidos DA

更新日期：2018-09-01 00:00:00

abstract：:The present study aimed to investigate changes of T-regulatory (Treg) and T-helper (Th)17 cells as well as cytokines in peripheral blood of children with acute bronchitis, and to explore the roles of these cells in the pathogenesis of acute bronchitis. A total of 126 children who had presented at Renji Hospital (Shang...

journal_title：Experimental and therapeutic medicine

authors： Tu Z,Xue H,Chen W,Cao L,Zhang W

更新日期：2017-10-01 00:00:00

abstract：:Phthalates are confirmed to have toxic effects on the reproductive system and are likely to have further damaging actions in humans. The present study explored the molecular mechanisms of the toxic effect of mono-(2-ethylhexyl) phthalate (MEHP) on mouse Sertoli cells. Cell apoptosis and proliferation assays were used ...

journal_title：Experimental and therapeutic medicine

authors： Wang L,Dou T,Li S,Liu Y

更新日期：2019-04-01 00:00:00

abstract：:Gastric ulcer is one of the most common chronic gastrointestinal diseases characterized by a significant defect in the mucosal barrier. Helicobacter pylori (H. pylori) infection and the frequent long-term use of non-steroidal anti-inflammatory drugs are major factors involved in gastric ulcer development. Acid inhibit...

journal_title：Experimental and therapeutic medicine

authors： Khoder G,Al-Menhali AA,Al-Yassir F,Karam SM

更新日期：2016-07-01 00:00:00

abstract：:Flos Chrysanthemi Indici (CI) is a traditional medicinal plant used in the treatment of inflammatory diseases. However, the pharmacological role of CI in metabolic diseases, especially in diseases induced by insulin metabolism disorders, remains poorly understood. In the present study, Drosophila melanogaster (Drosoph...

journal_title：Experimental and therapeutic medicine

authors： Bai Y,Li K,Shao J,Luo Q,Jin LH

更新日期：2018-09-01 00:00:00

abstract：:Bacterial infection is a key factor in airway inflammation. The present study describes the time-dependent changes in the leukocyte counts and cytokine levels of the bronchoalveolar lavage fluid (BALF) following subacute airway inflammation induced by lipopolysaccharide (LPS), a major component of the outer membranes ...

journal_title：Experimental and therapeutic medicine

authors： Liu L,Chen L,Wang Y,Yang H,Chen Y,Xu X,Zhou H,Jiang F,Li T,Wang J

更新日期：2012-12-01 00:00:00

abstract：:The aim of this study was to analyze the techniques for intraocular lens (IOL) implantation in patients with coloboma of the iris. A retrospective cohort study was used to analyze the degree of iris coloboma and the characteristics of the crystalline lens in 56 patients with iris coloboma. The patients with a lesser d...

journal_title：Experimental and therapeutic medicine

authors： Li J,Li Y,Hu Z,Kong L

更新日期：2014-06-01 00:00:00

abstract：:Osteonecrosis is a condition that frequently affects patients with systemic lupus erythematosus (SLE). However, reports on severe multifocal osteonecrosis involving more than three anatomical sites in patients with SLE are scarce. The present study describes a case of SLE with multifocal osteonecrosis involving all fo...

journal_title：Experimental and therapeutic medicine

authors： Sun S,Wang Q,Gong Y,Qi X,Liu J

更新日期：2019-10-01 00:00:00

abstract：:Acyclovir has been a frequently used antiviral agent in the clinical treatment of leukemia, acute encephalitis, malignant tumor and herpes simplex. The adverse effects of this drug have been widely described in clinical practice. In the present study, a case of a 35-year-old female patient diagnosed with herpes simple...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Cong Y,Teng Y

更新日期：2016-12-01 00:00:00

abstract：:The programmed death-1 (PD-1)/PD-ligand 1 (PD-L1) signaling pathway is a negative regulatory mechanism that inhibits T cell proliferation and cytokine production. Soluble PD-1 (sPD-1) and soluble PD-L1 (sPD-L1), are also involved in regulation of the PD-1/PD-L1 signaling pathway. In the present study, the expression l...

journal_title：Experimental and therapeutic medicine

authors： Li Y,Xiao Y,Su M,Zhang R,Ding J,Hao X,Ma Y

更新日期：2016-01-01 00:00:00

abstract：:The aim of the present study was to investigate the effects of feeder layers composed of various ratios of mouse embryonic fibroblasts (MEFs) and human foreskin fibroblasts (hFFs) on the growth of human embryonic stem cells (hESCs). In addition, the secretion levels of basic fibroblast growth factor (bFGF) by the feed...

journal_title：Experimental and therapeutic medicine

authors： Yang H,Qiu Y,Zeng X,Ding Y,Zeng J,Lu K,Li D

更新日期：2016-06-01 00:00:00

abstract：:Pancreatic necrosectomy (PN) following percutaneous catheter drainage (PCD) is an effective method of treating patients with necrotizing pancreatitis, however, the predictive factors for PN after PCD have not yet been identified. A total of 74 patients with suspected infected necrotizing pancreatitis (INP) and peripan...

journal_title：Experimental and therapeutic medicine

authors： Cao X,Cao F,Li A,Gao X,Wang XH,Liu DG,Fang Y,Guo DH,Li F

更新日期：2017-11-01 00:00:00

abstract：:Fungal prosthetic joint infections (PJI) and reports of their clinical investigation are rare. In addition, there has been little evidence regarding the outcome of the two-stage exchange protocol for the treatment of fungal PJI. In order to investigate the risk factors and clinical, microbiological and pathological fe...

journal_title：Experimental and therapeutic medicine

authors： Geng L,Xu M,Yu L,Li J,Zhou Y,Wang Y,Chen J

更新日期：2016-08-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/etm.2015.2631.]. ...

journal_title：Experimental and therapeutic medicine

authors： Wong AP,Kalinovsky T,Niedzwiecki A,Rath M

更新日期：2020-02-01 00:00:00

abstract：:Inflammatory diseases are an important health concern and have a growing incidence worldwide. Thus, developing novel and safe drugs to treat these disorders remains an important pursuit. Artemisia iwayomogi, locally known as Dowijigi (DJ), is a perennial herb found primarily in Korea and is used to treat various disea...

journal_title：Experimental and therapeutic medicine

authors： Kim SM,Vetrivel P,Kim HH,Ha SE,Saralamma VVG,Kim GS

更新日期：2020-03-01 00:00:00

abstract：:The aim of this study is to determine the accuracy rate of bronchopulmonary dysplasia (BPD) diagnosis and risk factors of short-term poor prognosis for premature infants. This study analyzed the clinical data of 81 premature infants (<32 weeks gestational age) with BPD, who were on oxygen therapy >28 days, and survive...

journal_title：Experimental and therapeutic medicine

authors： Du Z,Kong X,Ren Y,Feng Z,Huang J,Chen J,Wang R

更新日期：2017-10-01 00:00:00

abstract：:The aim of our study was to analyze the role of toll-like receptor 4 (TLR4)/nuclear factor (NF)-κB signal pathway on Hepcidin regulation in non-alcoholic fatty liver disease (NAFLD). A total of 60 male Sprague-Dawley rats were randomly divided into the control, NAFLD and intervention groups. Rats in the control group ...

journal_title：Experimental and therapeutic medicine

authors： Chen W,Wang X,Huang LI,Liu BO

更新日期：2016-01-01 00:00:00

abstract：:As an atherosclerotic disease, the process of peripheral arterial disease (PAD) is complicated and includes the abnormal proliferation of vascular smooth muscle. The current study aimed to determine the role of microRNA-15b (miR-15b) in the development of PAD and its associated mechanisms. Human vascular smooth muscle...

journal_title：Experimental and therapeutic medicine

authors： Sun Y,Gao Y,Song T,Yu C,Nie Z,Wang X

更新日期：2019-07-01 00:00:00

abstract：:Activated T cells rely on aerobic glycolysis and glutaminolysis in order to proliferate and differentiate into effector cells. Therefore, intervention in these metabolic pathways inhibits proliferation. The aim of the present study was to evaluate the effects of Krebs' cycle inhibition at the level of malate dehydroge...

journal_title：Experimental and therapeutic medicine

authors： Eleftheriadis T,Pissas G,Antoniadi G,Liakopoulos V,Stefanidis I

更新日期：2015-11-01 00:00:00

abstract：:The pathogenesis of acute liver failure has not been fully elucidated. The present study investigated the effects of the serum from patients with hepatitis E virus (HEV)-related acute liver failure on human liver cell survival and apoptosis, and evaluated the protective effects of anti-lipopolysaccharide(LPS) antibody...

journal_title：Experimental and therapeutic medicine

authors： Wu F,Wang M,Tian D

更新日期：2014-01-01 00:00:00

abstract：:Identifying the predominant microbial species in patients with ethmoidal sinusitis is conducive to its successful treatment. The aim of the present study was to determine the microbial composition and the predominant fungal and bacterial species in patients with ethmoidal sinusitis. A sample was obtained from 3 patien...

journal_title：Experimental and therapeutic medicine

authors： Zhang J,He S,Li Y,Lv M,Wei H,Qu B,Zheng Y,Hu C

更新日期：2018-11-01 00:00:00

abstract：:Chrysin is a major active ingredient of flavonoids, known to exhibit protective effects against various types of cancer. However, the anticancer role of chrysin against hepatocellular carcinoma (HCC) and the underlying molecular mechanisms remain unclear. In order to evaluate the effects of chrysin on cell viability a...

journal_title：Experimental and therapeutic medicine

authors： Zhang Q,Ma S,Liu B,Liu J,Zhu R,Li M

更新日期：2016-07-01 00:00:00

abstract：:3-Hydroxy-3-methylglutaric aciduria (3-HMG, OMIN 246450) is a rare autosomal recessive metabolic disorder caused by a deficiency of 3-hydroxy-3-methylglutaryl-CoA lyase, a key enzyme in leucine metabolism and ketone body synthesis. Acute episodes of 3-HMG may be triggered by fasting or infection, and symptoms include ...

journal_title：Experimental and therapeutic medicine

authors： Hao X,Wang J,Liu S,Chen Y,Zhang Y,Hao Y

更新日期：2016-06-01 00:00:00

abstract：:The activation of tunica albuginea myofibroblasts (MFs) serves an essential role in Peyronie's disease (PD). Increasing evidence has reported that adipose tissue-derived stem cells (ADSCs) have been demonstrated to attenuate the symptoms of PD in animal models. However, the mechanisms of the antifibrotic effects of AD...

journal_title：Experimental and therapeutic medicine

authors： Jiang H,Gao Q,Che X,Zhu L,Zhang Z,Chen Y,Dai Y

更新日期：2017-11-01 00:00:00

abstract：:The application of biomarkers in melanoma prognosis has been well recognized. However the ability of a single biomarker to predict melanoma patient outcome is usually limited. We previously examined the expression of ten biomarkers (Bim, BRG1, BRMS1, CTHRC1, ING4, NQO1, NF-κB-p50, PUMA, SNF5 and SOX4) in melanomas. To...

journal_title：Experimental and therapeutic medicine

authors： Li J,Zhang Z,Li G

更新日期：2011-01-01 00:00:00

abstract：:Effects of paraquat (PQ) on interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in macrophages were investigated. Different concentrations of PQ were added to mouse macrophage RAW264.7 for culture. According to different concentrations of PQ, mice were divided into micro concentration (0.01 mmol/l), low concentra...

journal_title：Experimental and therapeutic medicine

authors： Huang J,Ning N,Zhang W

更新日期：2019-03-01 00:00:00

abstract：:Atherosclerosis is caused by various factors, and Glabridin may have protective effects on the cardiovascular system. The purpose of the present study was to evaluate the effects of Glabridin on atherosclerosis and evaluate whether Glabridin attenuates arteriosclerosis and endothelial permeability by suppressing the m...

journal_title：Experimental and therapeutic medicine

authors： Wang G,Sun G,Wang Y,Yu P,Wang X,Zhou B,Zhu H

更新日期：2019-01-01 00:00:00

abstract：:The aim of this study was to explore the effect of electroacupuncture (EA) on immune function in patients undergoing supratentorial craniotomy. We also examined whether point specificity in EA was present. The study involved 29 patients undergoing craniotomy. The patients were divided into three groups: a control (C, ...

journal_title：Experimental and therapeutic medicine

authors： Li G,Li S,Wang B,An L

更新日期：2013-09-01 00:00:00