Overexpression of CD55 from Barrett's esophagus is associated with esophageal adenocarcinoma risk.

abstract：BACKGROUND AND AIM:Although rabeprazole (RPZ), a proton pump inhibitor, has been reported to have a bactericidal effect on Helicobacter pylori (H. pylori), no studies have been conducted regarding the effect of RPZ on gastric mucosal lesion formation caused by this bacterium. In the present study, we investigated the e...

journal_title：Journal of gastroenterology and hepatology

authors： Suzuki H,Miyazawa M,Nagahashi S,Sato M,Bessho M,Nagata H,Miura S,Ishii H

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND AND AIM:Serum cancer antigen (CA) 125 elevation has been reported in patients with liver disease, but it is poorly characterized. The present study aimed to evaluate the range of serum and ascitic CA 125 levels in patients with liver cirrhosis and to explore possible factors associated with CA 125 elevation....

journal_title：Journal of gastroenterology and hepatology

authors： Xiao WB,Liu YL

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND AIM:Ethnic differences in non-alcoholic steatohepatitis (NASH) are well-documented, but there has been no study on the prognosis of Japanese NASH patients with cirrhosis. Accordingly, we compared cirrhotic NASH with liver cirrhosis caused by chronic hepatitis C (LC-C) to clarify its clinical features and...

journal_title：Journal of gastroenterology and hepatology

authors： Yatsuji S,Hashimoto E,Tobari M,Taniai M,Tokushige K,Shiratori K

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIM:Although gastric hypermotility is one of the mechanisms proposed to explain the ulcerogenic action of indomethacin, the drug has shown relaxatory effects on isolated longitudinal and transverse rat gastric fundus. To explain the above discrepancy, the aim of this study was to investigate the effects ...

journal_title：Journal of gastroenterology and hepatology

authors： Keshavarz M,Afshin S,Djahanguiri B

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Habitual alcohol intake is known to aggravate the clinical outcome of hepatitis C virus (HCV)-related chronic liver diseases and to increase the risk of hepatocellular carcinoma. METHODS:To investigate the possible mechanism of these effects by alcohol, we examined 31 cases of HCV-related chronic liver dise...

journal_title：Journal of gastroenterology and hepatology

authors： Takahashi K,Takahashi T,Takahashi S,Watanabe K,Boku S,Matsui S,Arai F,Asakura H

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness (LS), measured by transient elastography, has been validated as a non-invasive surrogate for liver fibrosis. METHODS:We investigated the long-term predictive ability of LS for hepatocellular carcinoma (HCC) development and overall survival in 1146 patients with chronic hepatitis C by...

journal_title：Journal of gastroenterology and hepatology

authors： Nakagomi R,Tateishi R,Masuzaki R,Soroida Y,Iwai T,Kondo M,Fujiwara N,Sato M,Minami T,Uchino K,Enooku K,Nakagawa H,Asaoka Y,Kondo Y,Tanaka Y,Otsuka M,Kato N,Moriya K,Ikeda H,Koike K

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Hepatic steatosis is a histological characteristic in patients with chronic hepatitis C virus (HCV) infection. The aim of this study was to evaluate the prevalence of hepatic steatosis in Chinese patients with chronic hepatitis C, and to look for possible correlation with various histopathological c...

journal_title：Journal of gastroenterology and hepatology

authors： Hwang SJ,Luo JC,Chu CW,Lai CR,Lu CL,Tsay SH,Wu JC,Chang FY,Lee SD

更新日期：2001-02-01 00:00:00

abstract：:For basic scientists, the choice of starting a career in medical research is one made through a genuine interest in understanding the human disease processes and a desire to be at the forefront of new knowledge acquisition. However, more often than not, this decision is made without a great understanding of the career...

journal_title：Journal of gastroenterology and hepatology

authors： Ramm GA

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND AIM:A substantial number of patients with gastroesophageal reflux disease show symptomatic resistance to high-dose proton pump inhibitors. In those cases, prokinetics are possible candidates for treatment. The aim of the present study was to determine whether mosapride, a prokinetic agent, stimulates eso...

journal_title：Journal of gastroenterology and hepatology

authors： Koshino K,Adachi K,Furuta K,Ohara S,Morita T,Nakata S,Tanimura T,Miki M,Kinoshita Y

更新日期：2010-06-01 00:00:00

abstract：:Antipyrine metabolism is widely used as an index of the drug-metabolizing reserve of the liver. It is well known that metabolism of this drug is impaired in subjects with acute hepatitis or cirrhosis, but conflicting data have been reported regarding patients with chronic postinfectious hepatitis or liver cancer. We s...

journal_title：Journal of gastroenterology and hepatology

authors： Grieco A,Castellano R,Matera A,Marcoccia S,Di Rocco P,Ragazzoni E,Vecchio FM,Gasbarrini G

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND AIM:As bacterial resistance to clarithromycin limits the efficacy of clarithromycin-based regimens for Helicobacter pylori infection, attention has turned to quinolone-based rescue therapies. Resistance of H. pylori to both clarithromycin and quinolone can be predicted by genetic testing. Here, we used t...

journal_title：Journal of gastroenterology and hepatology

authors： Yamade M,Sugimoto M,Uotani T,Nishino M,Kodaira C,Furuta T

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND AIM:Liver fibrosis is an established determinant of prognosis and therapy in chronic hepatitis B (CHB). The role of fibroscan in assessing fibrosis in CHB remains unclear. Present study was designed to correlate fibroscan with liver biopsy and determine whether fibroscan can avoid liver biopsy in patient...

journal_title：Journal of gastroenterology and hepatology

authors： Goyal R,Mallick SR,Mahanta M,Kedia S,Shalimar,Dhingra R,Sharma H,Das P,Datta Gupta S,Panda S,Acharya SK

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND AIM:By array-comparative genomic hybridization, we demonstrated cyclin E as one of seven genes associated with hepatocellular carcinoma (HCC) development in Ku70 DNA repair-deficient mice. We therefore explored the hypothesis that during hepatocarcinogenesis, cyclin E kinase can overcome the inhibitory e...

journal_title：Journal of gastroenterology and hepatology

authors： Pok S,Wen V,Shackel N,Alsop A,Pyakurel P,Fahrer A,Farrell GC,Teoh NC

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND AIM:Colonic mucosal defects might be a route for bacterial invasion into the portal system, with subsequent hematogenous spread to the liver. We retrospectively investigated the results of colonoscopy and the clinical characteristics of patients with pyogenic liver abscess of colonic origin. METHODS:A t...

journal_title：Journal of gastroenterology and hepatology

authors： Jeong SW,Jang JY,Lee TH,Kim HG,Hong SW,Park SH,Kim SG,Cheon YK,Kim YS,Cho YD,Kim JO,Kim BS,Lee EJ,Kim TH

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND AIM:Disease activity and severity of ulcerative colitis (UC) is assessed using colonoscopy, which is invasive, costly and has poor patient acceptability. The role of non-invasive biomarkers of intestinal inflammation in the evaluation of patients with UC is not known. The aim of the study was to examine ...

journal_title：Journal of gastroenterology and hepatology

authors： Masoodi I,Kochhar R,Dutta U,Vaishnavi C,Prasad KK,Vaiphei K,Kaur S,Singh K

更新日期：2009-11-01 00:00:00

abstract：:A series of 51 patients with achalasia of the oesophagus treated by pneumatic dilatation between 1980 and 1988 is reported. Treatment was assessed as effective (no or minimal dysphagia) in 78% of patients, followed for a mean of 30 months. Thirty-four patients required only one dilatation and only two patients had mor...

journal_title：Journal of gastroenterology and hepatology

authors： Prewett EJ,Desmond PV,Breen KJ

更新日期：1990-11-01 00:00:00

abstract：:Gastrointestinal (GI) manifestations of leukemia occur in up to 25% of patients at autopsy, generally during relapse. Its presence varies with the type of leukemia and has been decreasing over time due to improved chemotherapy. Gross leukemic lesions are most common in the stomach, ileum, and proximal colon. Leukemia ...

journal_title：Journal of gastroenterology and hepatology

authors： Ebert EC,Hagspiel KD

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

journal_title：Journal of gastroenterology and hepatology

authors： Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Accumulation of endogenous opioids and overproduction of nitric oxide has been reported in cholestatic mice. It is well known that endogenous opioids and nitric oxide alter the susceptibility of experimental animals to different models of seizure. METHODS:The alterations in clonic seizure thresholds, induce...

journal_title：Journal of gastroenterology and hepatology

authors： Homayoun H,Sayyah M,Dehpour AR

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:In the gastric mucosa of portal hypertensive rats, adaptive cytoprotection against ethanol-induced damage is impaired. The aim of this study was to determine relation between impaired adaptive cytoprotection and oxidative stress. METHODS:Portal hypertension was produced in male Sprague-Dawley rats ...

journal_title：Journal of gastroenterology and hepatology

authors： Kawano Y,Ohta M,Eguchi H,Iwashita Y,Inomata M,Kitano S

更新日期：2013-04-01 00:00:00

abstract：AIM:To evaluate the characterization of liver hemangiomas and malignant tumors using power Doppler sonography before and after intravenous injection of a sonocontrast agent. METHODS:Forty-five patients with 57 liver tumors (22 hemangiomas, 24 metastases, 10 hepatocellular carcinomas (HCC) and one cholangiocellular car...

journal_title：Journal of gastroenterology and hepatology

authors： Karabacakoglu A,Karakose S,Cil AS,Kaya A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Histological examination of specimens obtained by forceps biopsy sampling of gastric lesions is of limited accuracy, and their management on this basis is therefore controversial. Endoscopic mucosal resection (EMR) was initially developed in Japan for the resection of early gastric cancer (EGC). The...

journal_title：Journal of gastroenterology and hepatology

authors： Szalóki T,Tóth V,Németh I,Tiszlavicz L,Lonovics J,Czakó L

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND AIM:Differentially expressed (DE) genes detected at the population-level through case-control comparison provide no information on the dysregulation frequencies of DE genes in a cancer. In this work, we aimed to identify the genes with universally upregulated or downregulated expressions in colorectal ca...

journal_title：Journal of gastroenterology and hepatology

authors： Song K,Su W,Liu Y,Zhang J,Liang Q,Li N,Guan Q,He J,Bai X,Zhao W,Guo Z

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:To elucidate the cause of possible occurrence of reflux esophagitis after Helicobacter pylori eradication, gastric and esophageal function among H. pylori infected Japanese patients were evaluated both before and after eradication therapy. METHODS:Nine H. pylori-positive patients were studied before and 6 m...

journal_title：Journal of gastroenterology and hepatology

authors： Tanaka I,Tatsumi Y,Kodama T,Kato K,Fujita S,Mitsufuji S,Kashima K

更新日期：2004-03-01 00:00:00

abstract：:Capsules (8 x 30 mm) of technetium-99m pertechnetate were designed for measurement of portal blood flow. Most of the radionuclide entered the superior mesenteric vein. The capsule was taken orally and monitored with a collimator for scintigraphy until it reached the small intestine, when a magnetic field completed an ...

journal_title：Journal of gastroenterology and hepatology

authors： Shiomi S,Kuroki T,Ueda T,Nishiguchi S,Nakajima S,Kobayashi K,Kurai O,Ikeoka N,Monna T,Ochi H

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND AND AIM:Controversies remain over the need for antiulcer treatment following 1-week eradication triple therapy for Helicobacter pylori-positive peptic ulcers. The usefulness of combination therapy for gastric ulcers in Japanese patients, which consists of H. pylori eradication followed by gastroprotective th...

journal_title：Journal of gastroenterology and hepatology

authors： Terano A,Arakawa T,Sugiyama T,Yoshikawa T,Haruma K,Asaka M,Shimosegawa T,Sakaki N,Ishii H,Sakamoto C,Takahashi S,Kinoshita Y,Fujioka T,Kobayashi K

更新日期：2006-01-01 00:00:00

abstract：:Previous research from this laboratory using a continuous enteral ethanol (EtOH) administration model demonstrated that Kupffer cells are pivotal in the development of EtOH-induced liver injury. When Kupffer cells were destroyed using gadolinium chloride (GdCl3 ) or the gut was sterilized with polymyxin B and neomycin...

journal_title：Journal of gastroenterology and hepatology

authors： Thurman RG,Bradford BU,Iimuro Y,Knecht KT,Arteel GE,Yin M,Connor HD,Wall C,Raleigh JA,Frankenberg MV,Adachi Y,Forman DT,Brenner D,Kadiiska M,Mason RP

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND AIM:HFE mutations, a common cause of hereditary hemochromatosis (HH), are reportedly associated with hepatic iron overload, severe liver fibrosis, and good response to interferon treatment in European patients with chronic hepatitis C (CHC). HH shows ethnicity-based differences and little is known about ...

journal_title：Journal of gastroenterology and hepatology

authors： Ishizu Y,Katano Y,Honda T,Hayashi K,Ishigami M,Itoh A,Hirooka Y,Nakano I,Goto H

更新日期：2012-06-01 00:00:00

abstract：:Helicobacter pylori is present in infected patients not only on the gastric epithelial cell surface but also in gastric mucus. We developed a competitive polymerase chain reaction (cPCR) method for quantitative measurement of H. pylori in gastric mucus. The aim of this study was to determine the number of H. pylori in...

journal_title：Journal of gastroenterology and hepatology

authors： Furuta T,Takashima M,Futami H,Arai H,Hanai H,Kaneko E

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND AIM:Fecal calprotectin (FC) has become a reliable biomarker for intestinal inflammation in inflammatory bowel diseases (IBDs). However, a simple and rapid assay to replace conventional ELISA is necessary for wider use in clinical practice. In this study, we investigated the usefulness of a novel method f...

journal_title：Journal of gastroenterology and hepatology

authors： Inoue K,Aomatsu T,Yoden A,Okuhira T,Kaji E,Tamai H

更新日期：2014-01-01 00:00:00