The prognostic significance of lung function in stable heart failure outpatients.

Abstract:

BACKGROUND:This study investigated the impact on all-cause mortality of airflow limitation indicative of chronic obstructive pulmonary disease or restrictive spirometry pattern (RSP) in a stable systolic heart failure population. HYPOTHESIS:Decreased lung function indicates poor survival in heart failure. METHODS:Inclusion criteria: NYHA class II-IV and left ventricular ejection fraction (LVEF) < 45%. Prognosis was assessed with multivariate Cox proportional hazards models. Two criteria of obstructive airflow limitation were applied: FEV1 /FVC < 0.7 (GOLD), and FEV1 /FVC < lower limit of normality (LLN). RSP was defined as FEV1 /FVC > 0.7 and FVC<80% or FEV1 /FVC > LLN and FVC

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Plesner LL,Dalsgaard M,Schou M,Køber L,Vestbo J,Kjøller E,Iversen K

doi

10.1002/clc.22802

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

1145-1151

issue

11

eissn

0160-9289

issn

1932-8737

journal_volume

40

pub_type

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