Assessment of cytology and mucin 2 in colorectal mucus collected from patients with inflammatory bowel disease: Results of a pilot trial.

abstract：BACKGROUND AND AIM:We assessed whether the two regimens of pegylated alpha-interferon-2b (PEG-IFN-alpha2b) plus ribavirin and pegylated alpha-interferon-2a (PEG-IFN-alpha2a) plus ribavirin showed differences in terms of sustained virological response, withdrawal due to side-effects and dose adjustment requirements in t...

journal_title：Journal of gastroenterology and hepatology

authors： Escudero A,Rodríguez F,Serra MA,Del Olmo JA,Montes F,Rodrigo JM

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Insulin-like growth factors (IGFs) are closely related to hepatocellular carcinoma growth. The study aim was to investigate the effects of IGF-IR and IGF-IIR antisense gene transfection on the biological behaviors of SMMC-7721 human hepatoma cells. METHODS:7721-IGF-IR-AS cells (human hepatoma SMMC-...

journal_title：Journal of gastroenterology and hepatology

authors： Yang JM,Chen WS,Liu ZP,Luo YH,Liu WW

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND AIM:T-cell activation, mediated by the interaction with major histocompatibility complex (MHC)-peptide complexes and B7 costimulatory molecules on antigen-presenting cells, is an essential event in the pathogenesis of inflammatory bowel disease (IBD). We investigated the expression of B7 costimulatory mo...

journal_title：Journal of gastroenterology and hepatology

authors： Grose RH,Howarth GS,Xian CJ,Hohmann AW

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND AIM:Helicobacter pylori cagA can be classified into mainly two types (East-Asian-type and Western-type cagA) according to the repeat regions located in the 3' region. Recent studies showed that the Western-type cagA in strains from Okinawa, Japan formed a different cluster (J-Western-type cagA subtype). ...

journal_title：Journal of gastroenterology and hepatology

authors： Matsuo Y,Shiota S,Matsunari O,Suzuki R,Watada M,Binh TT,Kinjo N,Kinjo F,Yamaoka Y

更新日期：2013-02-01 00:00:00

abstract：:Gastric varices (GVs) are a major complication of portal hypertension in patients with liver cirrhosis. The mortality rate associated with the bleeding from GVs is not low. Balloon-occluded retrograde transvenous obliteration (BRTO) was first introduced by Kanagawa et al. as a treatment for isolated GVs in 1994. It ha...

journal_title：Journal of gastroenterology and hepatology

authors： Kobayakawa M,Ohnishi S,Suzuki H

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIM:Functional gastrointestinal disorders are the most common disorders in gastroenterology and are currently considered as gut-brain interaction disorders with multiple related factors including motility disturbance. However, high-resolution manometry (HRM) had revealed a new disease concept known as mi...

journal_title：Journal of gastroenterology and hepatology

authors： Sato H,Takahashi K,Mizuno KI,Hashimoto S,Kawata Y,Mizusawa T,Tominaga K,Yokoyama J,Terai S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND AND AIM:In the condition of high prevalence of non-alcoholic fatty liver disease (NAFLD), a new diagnostic algorithm to efficiently identify NAFLD patients with significant fibrosis is urgently required. We evaluated the predictive ability of the fibrosis-4 index (FIB-4 index) for significant liver fibrosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Tomeno W,Imajo K,Kuwada Y,Ogawa Y,Kikuchi M,Honda Y,Kato T,Kessoku T,Kirikoshi H,Yoneda M,Kitahora T,Saito S,Ozawa Y,Nakajima A

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND AIM:In Japan, peptic ulcer disease (PUD) is treated clinically with a combination of a mucosal protectant and acid suppressants, but there is scant information regarding the effects of these drugs on normal gastric mucus cells. In the present study, the effects of co-administration of methylmethionine su...

journal_title：Journal of gastroenterology and hepatology

authors： Ichikawa T,Ito Y,Saegusa Y,Iwai T,Goso Y,Ikezawa T,Ishihara K

更新日期：2009-03-01 00:00:00

abstract：:The prevalence of colorectal cancer is increasing in Asia. However, the age-standardized rate has reached a plateau in some countries. Some studies have shown a male predominance difference and increasing risk in the elderly, but not in the younger population. 'Right shifting' of colorectal cancer, not accountable by ...

journal_title：Journal of gastroenterology and hepatology

authors： Yee YK,Tan VP,Chan P,Hung IF,Pang R,Wong BC

更新日期：2009-12-01 00:00:00

abstract：:A frequent association of biliary tract carcinoma and anomalous pancreaticobiliary ductal union (APBD) is well recognized, especially gall-bladder carcinoma in undilated type APBD. However, little is known about the presence and incidence of adenomyomatosis (AMT) of the gall-bladder, a presumed premalignant lesion, in...

journal_title：Journal of gastroenterology and hepatology

authors： Tanno S,Obara T,Maguchi H,Fujii T,Mizukami Y,Shudo R,Takahashi K,Nishino N,Arisato S,Ura H,Kohgo Y

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND AND AIM:This multinational (Taiwan, South Korea, Russia) phase 3 study evaluated the all-oral, ribavirin-free, fixed-dose combination (DCV-TRIO) of daclatasvir (NS5A inhibitor) 30 mg, asunaprevir (NS3 inhibitor) 200 mg, and beclabuvir (NS5B inhibitor) 75 mg, in patients with chronic hepatitis C virus genotyp...

journal_title：Journal of gastroenterology and hepatology

authors： Kao JH,Yu ML,Peng CY,Heo J,Chu CJ,Chang TT,Lee YJ,Hu TH,Yoon KT,Paik SW,Lim YS,Ahn SH,Isakov V,McPhee F,Hu W,Scott Swenson E,Yin PD,Treitel M

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate the relationship between human leptin receptor (LEPR) gene G3057A polymorphism and type 2 diabetes mellitus (T2DM) patients complicated with or without non-alcoholic fatty liver disease (NAFLD). METHODS:Two hundred and sixteen cases of newly diagnosed T2DM patients (104 cases complica...

journal_title：Journal of gastroenterology and hepatology

authors： Lu H,Sun J,Sun L,Shu X,Xu Y,Xie D

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIM:It has been reported that immunological factors, such as the T-helper cell (Th)1/Th2 ratio, play a part in the mechanisms for the antihepatitis C virus (HCV) effect of the interferon (IFN) alpha-2b plus ribavirin combination therapy. By using flow cytometry, we examined this ratio during a 24-week co...

journal_title：Journal of gastroenterology and hepatology

authors： Fujimoto T,Tomimatsu M,Iga D,Endo H,Otsuka K

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND AIM:In high or moderate risk populations, periodic surveillance of patients at risk of progression from gastric precursor lesions (PL) to gastric cancer (GC) is the most effective strategy for reducing the burden of GC. Incomplete type of intestinal metaplasia (IIM) may be considered as the best candidat...

journal_title：Journal of gastroenterology and hepatology

authors： González CA,Sanz-Anquela JM,Companioni O,Bonet C,Berdasco M,López C,Mendoza J,Martín-Arranz MD,Rey E,Poves E,Espinosa L,Barrio J,Torres MÁ,Cuatrecasas M,Elizalde I,Bujanda L,Garmendia M,Ferrández Á,Muñoz G,Andreu V

更新日期：2016-05-01 00:00:00

abstract：:Pulmonary hypertension is now recognized to be a rare association of liver disease and portal hypertension. This report describes the slow resolution of symptomatic pulmonary hypertension in a 33-year-old woman with cirrhosis who underwent isolated liver transplantation. The patient survived the surgery and perioperat...

journal_title：Journal of gastroenterology and hepatology

authors： Levy MT,Torzillo P,Bookallil M,Sheil AG,McCaughan GW

更新日期：1996-08-01 00:00:00

abstract：:The Steering Committee for the Prevention and Control of Infectious Diseases in Asia recently conducted a survey of primary-care physicians in Asia, which revealed that many physicians administer boosters in their clinical practice and that there is considerable variation and uncertainty among physicians regarding thi...

journal_title：Journal of gastroenterology and hepatology

authors： John TJ,Cooksley G,Steering Committee for the Prevention and Control of Infectious Diseases in Asia.

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND AIM:Splenomegaly in a common finding in liver cirrhosis that should determine changes in the spleen's density because of portal and splenic congestion and/or because of tissue hyperplasia and fibrosis. These changes might be quantified by elastography, so the aim of the study was to investigate whether s...

journal_title：Journal of gastroenterology and hepatology

authors： Stefanescu H,Grigorescu M,Lupsor M,Procopet B,Maniu A,Badea R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND & AIMS:Both medications with beta-blockers and isosorbide-5-mononitrate and endoscopic variceal ligation have been proven plausible in the prevention of variceal rebleeding. However, the relative efficacy and safety of the combined treatment for preventing rebleeding remains unresolved. METHODS:Patients wit...

journal_title：Journal of gastroenterology and hepatology

authors： Lo GH,Chen WC,Chan HH,Tsai WL,Hsu PI,Lin CK,Chen TA,Lai KH

更新日期：2009-06-01 00:00:00

abstract：:Barrett's esophagus (BE), a common condition, is the only known precursor to esophageal adenocarcinoma (EAC). There is uncertainty about the best way to manage BE as most people with BE never develop EAC and most patients diagnosed with EAC have no preceding diagnosis of BE. Moreover, there have been recent advances i...

journal_title：Journal of gastroenterology and hepatology

authors： Whiteman DC,Appleyard M,Bahin FF,Bobryshev YV,Bourke MJ,Brown I,Chung A,Clouston A,Dickins E,Emery J,Eslick GD,Gordon LG,Grimpen F,Hebbard G,Holliday L,Hourigan LF,Kendall BJ,Lee EY,Levert-Mignon A,Lord RV,Lord SJ

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND AIM:Recently, microRNAs (miRNA) have been linked to the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH). First transcribed as pri-miRNA, these molecules are further processed by a complex of endonuclear and cytosolic RNA binding molecu...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma H,Estep M,Birerdinc A,Afendy A,Moazzez A,Elariny H,Goodman Z,Chandhoke V,Baranova A,Younossi ZM

更新日期：2013-08-01 00:00:00

abstract：:To identify the preneoplastic lesions of hepatocellular carcinoma and the fine structure of preneoplastic hepatocytes, we studied proliferative conditions in cirrhosis of the liver. In all, 46 foci of cellular alteration (FCA), three regions of adenomatous hyperplasia (ADH), and 21 small hepatocellular carcinomas (sHC...

journal_title：Journal of gastroenterology and hepatology

authors： Seki S,Sakaguchi H,Kawakita N,Yanai A,Tamori A,Yabusako T,Nishiguchi S,Kuroki T,Kobayashi K,Monna T

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND AND AIM:Data about the efficacy of de novo combination therapies, or optimization strategy by adding the other drug based on the virological response at week 24 of low genetic barrier antiviral agents is still limited. This study aimed to compare the efficacy at week 104 of lamivudine monotherapy (MONO), lam...

journal_title：Journal of gastroenterology and hepatology

authors： Liang X,Cheng J,Sun Y,Chen X,Li T,Wang H,Jiang J,Chen X,Long H,Tang H,Yu Y,Sheng J,Chen S,Niu J,Ren H,Shi J,Dou X,Wan M,Jiang J,Xie Q,Shi G,Ning Q,Chen C,Tan D,Ma H,Sun J,Jia J,Zhuang H,Hou J

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND AIM:Palliative endoscopic or percutaneous biliary drainage is used for unresectable advanced hilar cancer (HC). The best option for drainage in Bismuth type III or IV HC has not been established. The aims of this study are to identify factors predictive of endoscopic stenting failure and evaluate the eff...

journal_title：Journal of gastroenterology and hepatology

authors： Jang SI,Hwang JH,Lee KH,Yu JS,Kim HW,Yoon CJ,Lee YS,Paik KH,Lee SH,Lee DK

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND AIM:Safety and efficacy data on endoscopic treatment of duodenal neoplasm are limited. We suggest the technical feasibility of endoscopic procedures by evaluating the results of endoscopic treatment for nonampullary duodenal adenoma and adenocarcinoma. METHODS:Forty-five patients who underwent endoscopi...

journal_title：Journal of gastroenterology and hepatology

authors： Seo JY,Hong SJ,Han JP,Jang HY,Myung YS,Kim C,Lee YN,Ko BM

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of the study was to develop a method of quantitation of endoscopic ultrasonography (EUS) changes of chronic pancreatitis (CP). METHODS:Twenty-three patients with chronic pancreatitis by EUS were compared with nine normal subjects. Hyperechogenicity was evaluated as the size of the hyperechoi...

journal_title：Journal of gastroenterology and hepatology

authors： Irisawa A,Mishra G,Hernandez LV,Bhutani MS

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND AIM:Nonattendance of outpatient colonoscopy leads to inefficient use of health-care resources. We aimed to study the effectiveness of using Short Message Service (SMS) reminder prior in patients scheduled for outpatient colonoscopy on their nonattendance rate. METHODS:Patients who scheduled for an outpa...

journal_title：Journal of gastroenterology and hepatology

authors： Lam TYT,Hui AJ,Sia F,Wong MY,Lee CCP,Chung KW,Lau JYW,Wu PI,Sung JJY

更新日期：2020-08-16 00:00:00

abstract：BACKGROUND AND AIM:Although several meta-analyses suggested that sequential therapy (SQT) is superior to standard triple therapy (STT) for the eradication of Helicobacter pylori, these results were mainly based on the studies from Italy. The aim of this study was to assess the efficacy of 10-day SQT for H. pylori infec...

journal_title：Journal of gastroenterology and hepatology

authors： Yoon H,Lee DH,Kim N,Park YS,Shin CM,Kang KK,Oh DH,Jang DK,Chung JW

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The present study examined the effects of NS-398, a specific cyclo-oxygenase-2 inhibitor, on gastric mucosal cell kinetics and gastric wound healing following acid-induced injury. METHODS:Male Sprague-Dawley rats were fasted for 24 h and then 0.6 mol/L hydrochloric acid (HCl; 1 mL) was administered...

journal_title：Journal of gastroenterology and hepatology

authors： Sun WH,Tsuji S,Tsujii M,Gunawan ES,Sawaoka H,Kawai N,Iijima H,Kimura A,Kakiuchi Y,Yasumaru M,Sasaki Y,Kawano S,Hori M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND AIM:The activation of Rho proteins has been shown to lead to loss of polarity in cancer cells, as well as reorganization of the cytoskeleton and facilitation of cell motility, possibly resulting in their malignant potential. The clinicopathological significance of RhoA, however, is not yet well known in ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang D,Dou K,Xiang H,Song Z,Zhao Q,Chen Y,Li Y

更新日期：2007-11-01 00:00:00

abstract：:Apoptosis, a programmed cell death, was ignored, just like Helicobacter pylori, only to reappear recently. However, the number of current publications dealing with apoptosis or H. pylori has increased exponentially. Although gastric epithelial apoptosis is a programmed physiological event in the superficial aspect of ...

journal_title：Journal of gastroenterology and hepatology

authors： Suzuki H,Ishii H

更新日期：2000-03-01 00:00:00