Abstract:
:A simulation method is presented for the demographic and genetic variation of age structured haploid populations. First, we use matrix analytic methods to derive an equilibrium distribution for the age class sizes conditioned on the total population size. Knowledge of this distribution eliminates the need of a burn-in time in simulations. Next, we derive the distribution of the alleles at a polymorphic locus in various age classes given the allele frequencies in the total population and the age size composition. For the time dynamics, we start by simulating the dynamics for the total population. In order to generate the inheritance of the alleles, we derive their distribution conditionally on the simulated population sizes. This method enables a fast simulation procedure of multiple loci in linkage equilibrium.
journal_name
Math Bioscijournal_title
Mathematical biosciencesauthors
Olsson F,Hössjer Odoi
10.1016/j.mbs.2015.08.003subject
Has Abstractpub_date
2015-10-01 00:00:00pages
45-51eissn
0025-5564issn
1879-3134pii
S0025-5564(15)00157-1journal_volume
268pub_type
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