Metabolic imaging in obesity: underlying mechanisms and consequences in the whole body.

abstract：:Converging lines of evidence indicate that withdrawal from prolonged exposure to stimulants and alcohol results in synaptic deficits of both dopamine (DA) and serotonin (5-HT). According to the dual deficit model proposed by the authors, DA dysfunction during cocaine or alcohol withdrawal underlies anhedonia and psych...

journal_title：Annals of the New York Academy of Sciences

authors： Rothman RB,Partilla JS,Dersch CM,Carroll FI,Rice KC,Baumann MH

更新日期：2000-09-01 00:00:00

abstract：:Insulin-like growth factor-I (IGF-I) and IGF-I receptor (IGF-IR), despite their well-known roles in cell survival and proliferation, can also weakly enhance apoptosis. To study the relationships between the IGF-IR and Bax as well as Bak, 144 cases of colorectal cancer were examined by immunohistochemistry, using the a...

journal_title：Annals of the New York Academy of Sciences

authors： Koda M,Reszec J,Sulkowska M,Kanczuga-Koda L,Sulkowski S

更新日期：2004-12-01 00:00:00

abstract：:Although it is now well established that imidazoline receptors and alpha 2-adrenoceptors are discrete entities with distinct endogenous ligands, the two receptor classes apparently have several common features. While the catecholamines stimulate alpha 2-adrenoceptors but not imidazoline receptors, agmatine, a guanidin...

journal_title：Annals of the New York Academy of Sciences

authors： Hieble JP,Ruffolo RR Jr

更新日期：1995-07-12 00:00:00

abstract：:Peripheral administration of lipopolysaccharide (LPS) in an amount that produces acute stress has been found to affect the catecholamine systems in the brain. Acute peripheral LPS administration activated norepinephrine (NE) metabolism in the locus ceruleus (LC). Approximately 40% of murine LC neurons project to the o...

journal_title：Annals of the New York Academy of Sciences

authors： Ota A,Mori K,Kaneko YS,Nakashima A,Nagatsu I,Nagatsu T

更新日期：2008-12-01 00:00:00

abstract：:B-1 cells represent a subpopulation of B cells that has been extensively studied in mice and shown to spontaneously generate natural antibody that provides antimicrobial protection and helps dispose of cellular debris. Mouse B-1 cells originate from distinct progenitors and express additional immune properties that in...

journal_title：Annals of the New York Academy of Sciences

authors： Rothstein TL,Quach TD

更新日期：2015-12-01 00:00:00

abstract：:The concepts of the ventral striatopallidal system and extended amygdala have significantly improved our understanding of basal forebrain organization. As a result of these and other advances during the last twenty years, many of the most prominent basal forebrain structures, including the nucleus accumbens, olfactory...

journal_title：Annals of the New York Academy of Sciences

authors： de Olmos JS,Heimer L

更新日期：1999-06-29 00:00:00

abstract：:The results of this study suggest that reperfusion of ischemic myocardium may lead to the peroxisomal disorder both functionally and biochemically. An alkyl glycerol such as chimyl alcohol can protect the ischemic heart from the reperfusion injury probably by enhancing the plasmalogen synthesis. ...

journal_title：Annals of the New York Academy of Sciences

authors： Maulik N,Tosaki A,Engelman RM,Cordis GA,Das DK

更新日期：1994-06-17 00:00:00

abstract：:Despite a globally uniform increase in the concentrations of emitted greenhouse gases, radiatively forced surface warming can have significant spatial variations. These define warming patterns that depend on preexisting climate states and through atmospheric and oceanic dynamics can drive changes of the hydrological c...

journal_title：Annals of the New York Academy of Sciences

authors： Ma J,Zhou L,Foltz GR,Qu X,Ying J,Tokinaga H,Mechoso CR,Li J,Gu X

更新日期：2020-07-01 00:00:00

abstract：:The hypothalamic-pituitary-adrenocortical (HPA) axis is a major neuroendocrine system involved in the regulation of numerous physiological processes and in adaptation to stress. A wide range of variability can be observed in all the components of the system, and the contribution of genetic factors has been shown in th...

journal_title：Annals of the New York Academy of Sciences

authors： Mormede P,Foury A,Barat P,Corcuff JB,Terenina E,Marissal-Arvy N,Moisan MP

更新日期：2011-03-01 00:00:00

abstract：:Dopaminergic signaling in the brain is primarily modulated by dopamine transporters (DATs), which actively translocate extraneuronal dopamine back into dopaminergic neurons. Transporter proteins are highly dynamic, continuously trafficking between plasmalemmal and endosomal membranes. Changes in DAT membrane trafficki...

journal_title：Annals of the New York Academy of Sciences

authors： Schmitt KC,Reith ME

更新日期：2010-02-01 00:00:00

abstract：:A linear stability analysis is presented for variable-viscosity miscible fluids in an unstable configuration; that is, a heavier fluid placed above a lighter one in a vertically oriented capillary tube. The initial interface thickness is treated as a parameter to the problem. The analysis is based on the three-dimensi...

journal_title：Annals of the New York Academy of Sciences

authors： Meiburg E,Vanaparthy SH,Payr MD,Wilhelm D

更新日期：2004-11-01 00:00:00

abstract：:According to the fetal origin of adult diseases hypothesis, the intrauterine environment through developmental plasticity may permanently influence long-term health and disease. Therefore, intrauterine growth restriction (IUGR), due either to maternal, placental, or genetic factors, may permanently alter the endocrine...

journal_title：Annals of the New York Academy of Sciences

authors： Kanaka-Gantenbein C

更新日期：2010-09-01 00:00:00

abstract：:Obesity is a multifactorial heterogenous condition. The location of excess fat on the body determines the risk of morbidity and mortality for significant disease. Visceral, or intraabdominal, fat is the fat depot most highly associated with illness and death from cardiocerebrovascular disease and diabetes. Visceral fa...

journal_title：Annals of the New York Academy of Sciences

authors： Peeke PM,Chrousos GP

更新日期：1995-12-29 00:00:00

abstract：:The amygdala and orbitofrontal cortex (OFC) are often thought of as components of a neural circuit that assigns affective significance--or value--to sensory stimuli so as to anticipate future events and adjust behavioral and physiological responses. Much recent work has been aimed at understanding the distinct contrib...

journal_title：Annals of the New York Academy of Sciences

authors： Salzman CD,Paton JJ,Belova MA,Morrison SE

更新日期：2007-12-01 00:00:00

abstract：:Astrakhan fever is a summer spotted fever resembling Mediterranean spotted fever, endemic in Astrakhan, a region of Russia located by the Caspian sea. Its agent is a spotted fever group rickettsia, member of the Rickettsia conorii complex, transmitted to humans by Rhipicephalus sanguineus and Rhipicephalus pumilio tic...

journal_title：Annals of the New York Academy of Sciences

authors： Fournier PE,Durand JP,Rolain JM,Camicas JL,Tolou H,Raoult D

更新日期：2003-06-01 00:00:00

abstract：:TT virus (TTV) is a recently described circular DNA virus of about 3.8 kb, which is related to the circoviridae viruses. It is commonly detected in healthy subjects and no association with any specific disease has been established. TTV was initially thought to be hepatotropic, but subsequent reports have shown that it...

journal_title：Annals of the New York Academy of Sciences

authors： Zhong S,Yeo W,Tang MW,Lin XR,Mo F,Ho WM,Hui P,Johnson PJ

更新日期：2001-09-01 00:00:00

abstract：:The dentate gyrus of the rat forms in three developmental phases, each of which is characterized by neuronal birth, migration and death. Recent evidence indicates that adrenal steroids regulate neuronal birth, death, and possibly migration throughout the life of the animal. However, the observation that very few neuro...

journal_title：Annals of the New York Academy of Sciences

authors： Gould E

更新日期：1994-11-14 00:00:00

abstract：:The aim of this study was to examine changes in muscle cell injury and antioxidant capacity of weightlifters following a 1-week intensive resistance-training regimen. Thirty-six female subjects participated in this study, and their ages ranged from 18 to 25 years. The sample group included 19 elite weightlifters with ...

journal_title：Annals of the New York Academy of Sciences

authors： Liu JF,Chang WY,Chan KH,Tsai WY,Lin CL,Hsu MC

更新日期：2005-05-01 00:00:00

abstract：:Significant advances have been made over the past few years concerning the cellular and molecular events underlying neuron death. Recently, it is becoming increasingly clear that some of genes induced during cerebral ischemia may actually serve to rescue the cell from death. However, the injured cell may not be capabl...

journal_title：Annals of the New York Academy of Sciences

authors： Yenari MA,Dumas TC,Sapolsky RM,Steinberg GK

更新日期：2001-06-01 00:00:00

abstract：:Posttranscriptional control of gene expression plays a key role in regulating gene expression in cells undergoing apoptosis. Cyclooxygenase-2 (COX-2) is a crucial enzyme in the conversion of arachidonic acid to prostaglandin E2 (PGE(2)) and is significantly upregulated in many types of adenocarcinomas. COX-2 overexpre...

journal_title：Annals of the New York Academy of Sciences

authors： Mukhopadhyay D,Jung J,Murmu N,Houchen CW,Dieckgraefe BK,Anant S

更新日期：2003-12-01 00:00:00

abstract：:The endocannabinoid system, through the cannabinoid receptor CB1, is involved in the modulation of adaptive responses to environmental conditions. However, little is known about the role of the cannabinergic system, particularly CB1 receptor expression, in relation to the effects induced by xenoestrogens concerning th...

journal_title：Annals of the New York Academy of Sciences

authors： Palermo FA,Angelini M,Cottone E,Virgili M,Franzoni MF,Mosconi G,Polzonetti-Magni AM

更新日期：2009-04-01 00:00:00

abstract：:The present study was designed to immunochemically identify a coronin-like protein in Babesia bovis, B. bigemina, B. divergens, and B. canis. A 2-kbp cDNA insert of B. bovis carried by plasmid BvN9 was sequenced by the dideoxichain-termination method on both strands. The cDNA insert contained a 1719-bp long open readi...

journal_title：Annals of the New York Academy of Sciences

authors： Figueroa JV,Precigout E,Carcy B,Gorenflot A

更新日期：2004-10-01 00:00:00

abstract：:Vestibular stimulation by head accelerations always involves multisensory activation of the vestibular, somatosensory, and visual systems. Over the past few years, galvanic vestibular stimulation (GVS) has become increasingly popular for testing vestibular function for clinical and research purposes. Although GVS prov...

journal_title：Annals of the New York Academy of Sciences

authors： Jahn K,Naessl A,Strupp M,Schneider E,Brandt T,Dieterich M

更新日期：2003-10-01 00:00:00

abstract：:Plasmacytoid dendritic cells (pDCs) are a rare population of circulating cells that selectively express Toll-like receptors (TLR)7 and TLR9 and have the capacity to produce large amounts of type I interferons (IFNs) in response to viruses or host-derived nucleic acid-containing complexes. Through the production of typ...

journal_title：Annals of the New York Academy of Sciences

authors： Lande R,Gilliet M

更新日期：2010-01-01 00:00:00

abstract：:Extension of mammalian health and life span has been achieved using various dietary interventions. We previously reported that restricting dietary methionine (MET) content extends life span only when growth hormone signaling is intact (no life span increase in GH deficiency or GH resistance). To understand the metabol...

journal_title：Annals of the New York Academy of Sciences

authors： Brown-Borg HM,Rakoczy S,Wonderlich JA,Borg KE,Rojanathammanee L

更新日期：2018-04-01 00:00:00

abstract：:For various esophageal diseases, the search for alternative techniques for tissue repair has led to significant developments in basic and translational research in the field of tissue engineering. Applied to the esophagus, this concept is based on the in vitro combination of elements judged necessary for in vivo impla...

journal_title：Annals of the New York Academy of Sciences

authors： Arakelian L,Kanai N,Dua K,Durand M,Cattan P,Ohki T

更新日期：2018-12-01 00:00:00

abstract：:Mice deficient for complement factors C3, C4, or C5 are resistant to experimental autoimmune myasthenia gravis (EAMG). Acetylcholine receptor (AChR) immune lymph node cells (LNC) of C3 deficient mice produce less interleukin 6 (IL-6), and EAMG-resistant IL-6 deficient mice have less serum C3. Increased serum C1q-circu...

journal_title：Annals of the New York Academy of Sciences

authors： Christadoss P,Tüzün E,Li J,Saini SS,Yang H

更新日期：2008-01-01 00:00:00

abstract：:Nanofluids consisting of nanometer-sized particles dispersed in base liquids are known to be effective in extending the saturated boiling regime and critical heat flux in pool boiling. The heat transfer characteristics of nanosilica suspensions with particle sizes of 10 and 20 nm in pool boiling with a suspended heati...

journal_title：Annals of the New York Academy of Sciences

authors： Kumar R,Milanova D

更新日期：2009-04-01 00:00:00

abstract：:Whether T cells promote bone loss following immobilization after spinal cord injury (SCI) remains undetermined. Therefore, wild-type (WT) and T cell-deficient (Tcrb-/- ) male mice underwent sham or contusion SCI to cause hindlimb paralysis. Femurs were isolated and distal and midshaft regions were evaluated by microco...

journal_title：Annals of the New York Academy of Sciences

authors： Sahbani K,Shultz LC,Cardozo CP,Bauman WA,Tawfeek HA

更新日期：2020-10-26 00:00:00

abstract：:Pheochromocytoma is a rare, surgically correctable cause of hypertension. Modern medical blockade has significantly improved patient survival and morbidity. The last decade has seen the identification of the genes responsible for several hereditary causes of pheochromocytoma. Evaluation of these patients has demonstra...

journal_title：Annals of the New York Academy of Sciences

authors： Walther MM

更新日期：2002-09-01 00:00:00