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Predictors of comorbid eating disorders and association with other obsessive-compulsive spectrum disorders in trichotillomania.

Abstract：

:Trichotillomania (TTM) and eating disorders (ED) share many phenomenological similarities, including ritualized compulsive behaviors. Given this, and that comorbid EDs may represent additional functional burden to hair pullers, we sought to identify factors that predict diagnosis of an ED in a TTM population. Subjects included 555 adult females (age range 18-65) with DSM-IV-TR TTM or chronic hair pullers recruited from multiple sites. 7.2% (N=40) of our TTM subjects met criteria for an ED in their lifetime. In univariable regression analysis, obsessive-compulsive disorder (OCD), Yale-Brown Obsessive Compulsive Scale (Y-BOCS) worst-ever compulsion and total scores, certain obsessive-compulsive spectrum disorders, anxiety disorder, attention-deficit/hyperactivity disorder (ADHD), and substance disorder all met the pre-specified criteria for inclusion in the multivariable analysis. In the final multivariable model, diagnosis of OCD (OR: 5.68, 95% CI: 2.2-15.0) and diagnosis of an additional body-focused repetitive behavior disorder (BFRB) (OR: 2.69, 95% CI: 1.1-6.8) were both associated with increased risk of ED in TTM. Overall, our results provide further support of the relatedness between ED and TTM. This finding highlights the importance of assessing for comorbid OCD and additional BFRBs in those with TTM. Future research is needed to identify additional predictors of comorbid disorders and to better understand the complex relationships between BFRBs, OCD and EDs.

journal_name

Compr Psychiatry

journal_title

Comprehensive psychiatry

authors

Greenberg E,Grant JE,Curley EE,Lochner C,Woods DW,Tung ES,Stein DJ,Redden SA,Scharf JM,Keuthen NJ

doi

10.1016/j.comppsych.2017.06.008

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

1-8

eissn

0010-440X

issn

1532-8384

pii

S0010-440X(17)30061-5

journal_volume

78

pub_type

杂志文章,多中心研究

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