Abstract:
OBJECTIVES:Vascular complications are one of the most common causes of early kidney transplant dysfunction. Contrast enhanced ultrasound increases sensitivity to vascular changes. The aim of this study was to assess the prevalence and size of vascular abnormalities in early renal transplants using 3D CEUS and the significance of perfusion defects on renal function. METHODS:Ninety-nine renal transplant patients underwent 3D CEUS after surgery to quantify perfusion defects as percentage total renal volume (TRV). Serum creatinine and estimated glomerular filtration rate (eGFR) were recorded up to 3 months post-surgery. RESULTS:Twenty participants had focal perfusion defects (0.2-43%TRV). There was a meaningful difference in patients with perfusion defects in eGFR at 1 month (90% CI 2.7-19.2 mL/min/1.73 m2) and 3 months (90% CI 1.9-19.6 mL/min/1.73 m2) and creatinine at 3 months (90% CI -56 - -8 μmol/L) using a predetermined clinical threshold. Perfusion defect size correlated well with both serum creatinine and eGFR at 3 months (R = 0.80, p ≤ 0.000 and 0.58, p = 0.038). No correlation was seen prior to 3 months. CONCLUSIONS:Perfusion defects in kidney transplants were more common than expected and were highly likely to reduce renal function at 1-3 months, and the size of the defect affected the degree of functional change at 3 months. KEY POINTS:• Perfusion defects were more common than previously thought. • Perfusion defects could be quantified using 3D CEUS. • The presence of even small perfusion defects may affect kidney function. • Size of perfusion defects correlated with subsequent kidney function at 3 months. • Potentially useful in informing clinician expectations of kidney function post-surgery.
journal_name
Eur Radioljournal_title
European radiologyauthors
Stenberg B,Wilkinson M,Elliott S,Caplan Ndoi
10.1007/s00330-017-4871-3subject
Has Abstractpub_date
2017-11-01 00:00:00pages
4525-4531issue
11eissn
0938-7994issn
1432-1084pii
10.1007/s00330-017-4871-3journal_volume
27pub_type
杂志文章abstract:OBJECTIVES:To determine whether positioning of the arm in adduction and internal rotation would improve the confidence in the diagnosis of Bankart lesions in first time shoulder dislocators. METHODS:Eleven patients were imaged on an open bore MRI within 1-6 days of traumatic shoulder dislocation with the arm adducted ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2655-3
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:The current gold standard in the assessment of lateral intracranial dural arteriovenous fistulas (LDAVF) is digital subtraction angiography (DSA). However, magnetic resonance imaging (MRI) is a non-invasive emerging tool for the evaluation of such lesions. The aim of our study was to compare the DSA to our 3...
journal_title:European radiology
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abstract:OBJECTIVES:To examine the added value of considering smooth hypointense rim in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced MRI as capsule appearance for diagnosing tumour capsules and hepatocellular carcinoma (HCC). METHODS:A total of 377 hepatic lesions (330 HCCs, 35 non-HCC malignancies and 12 benign) w...
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更新日期:2017-06-01 00:00:00
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journal_title:European radiology
pub_type: 已发布勘误
doi:10.1007/s00330-019-06333-2
更新日期:2019-12-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2015-11-01 00:00:00
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更新日期:2010-05-01 00:00:00
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journal_title:European radiology
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更新日期:1999-01-01 00:00:00
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更新日期:1996-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,评审
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更新日期:2005-06-01 00:00:00