Abstract：
INTRODUCTION:Acetaminophen is a commonly used analgesic/antipyretic; overdoses can lead to liver damage. Little is known about the relationship of health literacy to exceeding the recommended maximum daily dose (4 g). METHODS:Subjects were recruited at 23 U.S. malls in 2011. Health literacy was measured by Rapid Estimate of Adult Literacy in Medicine (REALM), classified as very low (VLL, score <45); low (LL, 45-60); or adequate (AL, >60). Participants completed a 7-day acetaminophen use diary by daily telephone interview; an exit interview covered demographics, physical/mental health, medical history, medication label reading, and medication-taking knowledge/attitudes. Acetaminophen products were identified from a comprehensive list; subjects were not required to know their medications contained acetaminophen. Seven hundred fifty-six subjects aged ≥18 years had taken acetaminophen in the past 30 days and completed 7 diary days with ≥1 day of acetaminophen use, plus the exit survey. Analysis was conducted in 2012-2014. RESULTS:VLL were more likely than AL individuals to exceed 4 g on ≥1 day (OR [95% CI]=3.8 [1.5, 9.6]; 4.0 [1.3, 12] after controlling for five REALM score-related factors). On usage days, VLL individuals were also more likely to exceed 4 g (3.3 [1.1, 10], by generalized estimating equations; 2.4 [0.9, 6.6], direct effect after accounting for mediation by other deviations from label recommendations). CONCLUSIONS:VLL individuals exceed the recommended maximum acetaminophen dose more often than AL individuals. Other identified characteristics related to health literacy do not explain this, but it is partly mediated by increased frequency of other label deviations.
journal_name
Am J Prev Medjournal_title
American journal of preventive medicineauthors
Kaufman DW,Kelly JP,Battista DR,Malone MK,Weinstein RB,Shiffman Sdoi
10.1016/j.amepre.2015.11.005subject
Has Abstractpub_date
2016-06-01 00:00:00pages
e183-e190issue
6eissn
0749-3797issn
1873-2607pii
S0749-3797(15)00732-1journal_volume
50pub_type
杂志文章abstract：:Rising obesity rates in the U.S. over the past several decades, particularly among children and adolescents, led to an increased focus on research addressing obesity prevention and public- and private-sector initiatives on healthy eating and physical activity. Groups conducting prevention initiatives recognized that t...
journal_title：American journal of preventive medicine
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abstract：CONTEXT:The "first 1,000 days"-conception through age 24 months-are critical for the development and prevention of childhood obesity. This study systematically reviews existing and ongoing interventions during this period, identifies gaps in current research, and discusses conceptual frameworks and opportunities for fu...
journal_title：American journal of preventive medicine
pub_type： 杂志文章,评审
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abstract：BACKGROUND:The purposes of this study are to examine the extent to which (1) more-healthy and less-healthy food choices are available to American secondary students in their schools, and (2) there are differences in the availability of such foods as a function of grade, racial/ethnic background, and socioeconomic statu...
journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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pub_type： 杂志文章,实务指引,评审
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journal_title：American journal of preventive medicine
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更新日期：1995-05-01 00:00:00
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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更新日期：1996-11-01 00:00:00
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更新日期：2008-08-01 00:00:00
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journal_title：American journal of preventive medicine
pub_type： 杂志文章
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更新日期：2020-12-23 00:00:00
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journal_title：American journal of preventive medicine
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更新日期：1997-05-01 00:00:00
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journal_title：American journal of preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1996-09-01 00:00:00
