Abstract：
INTRODUCTION:Tobacco use remains a leading modifiable cause of cancer incidence and premature mortality in the U.S. and globally. Despite increasing life expectancy worldwide, less is known about the effects of cigarette smoking on older populations. This study sought to determine the effects of smoking on mortality in older age. METHODS:Associations of mortality with self-reported age at smoking cessation, age at smoking initiation, and amount smoked after age 70 years were examined in 160,113 participants of the NIH-AARP Diet and Health Study aged >70 years. Participants completed a questionnaire detailing their smoking use in 2004-2005, and were followed for mortality through December 31, 2011. Analyses were conducted between 2014 and 2016. RESULTS:Relative to never smokers, current smokers were more likely to die during follow-up (hazard ratio, 3.18; 95% CI=3.04, 3.31). Furthermore, former smokers had lower risks than current smokers (hazard ratios for quitting between ages 30-39, 40-49, 50-59, and 60-69 years were 0.41 [95% CI=0.39, 0.43], 0.51 [95% CI=0.49, 0.54], 0.64 [95% CI=0.61, 0.67], and 0.77 [95% CI=0.73, 0.81], respectively). Among current smokers, mortality was inversely associated with age at initiation, but directly associated with the number of cigarettes smoked per day at age >70 years. CONCLUSIONS:As among younger people, lifetime cigarette smoking history is a key determinant of mortality after age 70 years.
journal_name
Am J Prev Medjournal_title
American journal of preventive medicineauthors
Nash SH,Liao LM,Harris TB,Freedman NDdoi
10.1016/j.amepre.2016.09.036subject
Has Abstractpub_date
2017-03-01 00:00:00pages
276-283issue
3eissn
0749-3797issn
1873-2607pii
S0749-3797(16)30517-7journal_volume
52pub_type
杂志文章abstract：CONTEXT:Worksite-based interventions have been shown to result consistently in significant improvements in weight- and health-related outcomes among the working adult population; however, applicability and effectiveness of studies has often been limited by inadequate reporting of age and ethnicity. This study aimed to ...
journal_title：American journal of preventive medicine
pub_type： 杂志文章,评审
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
pub_type： 杂志文章
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
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更新日期：2004-10-01 00:00:00
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journal_title：American journal of preventive medicine
pub_type： 杂志文章
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更新日期：1998-04-01 00:00:00
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journal_title：American journal of preventive medicine
pub_type： 杂志文章
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journal_title：American journal of preventive medicine
pub_type： 杂志文章
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
pub_type： 杂志文章,评审
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
pub_type： 杂志文章,随机对照试验
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更新日期：2011-01-01 00:00:00
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
pub_type： 杂志文章
doi：
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journal_title：American journal of preventive medicine
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journal_title：American journal of preventive medicine
pub_type： 杂志文章
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journal_title：American journal of preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：American journal of preventive medicine
pub_type： 杂志文章
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