Effects of hemodialysis on intraneural blood flow in end-stage kidney disease.

Abstract:

INTRODUCTION:We quantified intraneural blood flow (INBF) in 18 patients with end-stage kidney disease (ESKD) and examined its relationship with nerve size, neuropathy severity, and nerve excitability parameters. METHODS:Sonographic measurements of the median nerve were performed at the same site before and after hemodialysis. INBF was quantified by analyzing power Doppler sonograms to obtain the vessel score (VSc) and maximum perfusion intensity (MPI). Corresponding median motor nerve excitability studies were performed. Neuropathy severity was assessed using Total Neuropathy Score. RESULTS:A total of 39% of ESKD patients had detectable INBF compared with none in the control group (P < 0.0001). Patients with detectable INBF had larger nerves and more severe neuropathy (P < 0.01). INBF parameters were significantly reduced after a session of dialysis (VSc: P < 0.01; MPI: P < 0.01). A significant relationship was found between interdialytic change in INBF and changes in nerve excitability. CONCLUSIONS:Increased INBF is a potential marker for neuropathy severity in ESKD patients. Muscle Nerve 57: 287-293, 2018.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Borire AA,Arnold R,Pussell BA,Kwai NC,Visser LH,Simon NG,Kiernan MC,Krishnan AV

doi

10.1002/mus.25704

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

287-293

issue

2

eissn

0148-639X

issn

1097-4598

journal_volume

57

pub_type

杂志文章
  • Quantification of normal range of inflammatory changes in morphologically normal pediatric muscle.

    abstract::The aim of this study was to define normal ranges of histological features in pediatric muscle in comparison with muscle demonstrating inflammatory changes. Sixteen pediatric muscle biopsy samples, considered normal by standard histology, were analyzed for the presence of inflammatory cells, and the expression of neon...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20898

    authors: Varsani H,Newton KR,Li CK,Harding B,Holton JL,Wedderburn LR

    更新日期:2008-02-01 00:00:00

  • Time to failure of a sustained contraction is predicted by target torque and initial electromyographic bursts in elbow flexor muscles.

    abstract::The purpose of the study was to identify factors that could predict differences among individuals in the time to failure of a submaximal contraction. Twenty subjects (10 men, 25+/-6 years) supported an inertial load equivalent to 20% of the maximal voluntary contraction (MVC) force with the elbow flexor muscles for as...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20752

    authors: Rudroff T,Christou EA,Poston B,Bojsen-Møller J,Enoka RM

    更新日期:2007-05-01 00:00:00

  • Comparison of distal sympathetic with vagal function in diabetic neuropathy.

    abstract::We measured distal sympathetic and vagal function in 73 consecutive patients with diabetic neuropathy seen at the Mayo Autonomic Reflex Laboratory. Postganglionic sympathetic failure measured proximally within the foot occurred as commonly as vagal failure (58% and 55%, respectively) and occurred much more frequently ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880090703

    authors: Low PA,Zimmerman BR,Dyck PJ

    更新日期:1986-09-01 00:00:00

  • GNE myopathy in the bedouin population of Kuwait: Genetics, prevalence, and clinical description.

    abstract:INTRODUCTION:GNE myopathy is a rare recessive myopathy caused by mutations in the GNE gene. It is mainly a distal myopathy with relative sparing of the quadriceps muscle. METHODS:Patients with distal myopathies from Kuwait were examined and tested for the Middle Eastern GNE gene founder mutation, p.M743T. Patients wer...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26337

    authors: Alrohaif H,Pogoryelova O,Al-Ajmi A,Aljeryan LA,Alrashidi NH,Alefasi SA,Urtizberea A,Lochmüller H,Bastaki L

    更新日期:2018-11-01 00:00:00

  • Effects of treadmill training on microvascular remodeling in the rat after spinal cord injury.

    abstract:INTRODUCTION:The morphological characteristics of skeletal muscles innervated caudal to a spinal cord injury (SCI) undergo dramatic phenotypic and microvascular changes. METHOD:Female Sprague-Dawley rats received a severe contusion at thoracic level 9/10 and were randomly assigned to locomotor training, epidural stimu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26379

    authors: Kissane RWP,Wright O,Al'Joboori YD,Marczak P,Ichiyama RM,Egginton S

    更新日期:2019-03-01 00:00:00

  • Do A-waves help predict intravenous immunoglobulin response in multifocal motor neuropathy without block?

    abstract:INTRODUCTION:Are there electrophysiological findings that predict response to intravenous immunoglobulin (IVIg) in patients with lower motor neuron (LMN) syndromes without multifocal conduction block (MCB)? METHODS:We enrolled 9 patients with LMN syndromes without MCB to receive 18 weeks of IVIg therapy. Response was ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21914

    authors: Lange DJ,Nijjar R,Voustianiouk A,Seidel G,Panchal J,Wang AK

    更新日期:2011-04-01 00:00:00

  • Avoiding false-negative nerve conduction study in ulnar neuropathy at the elbow.

    abstract:INTRODUCTION:Ulnar nerve displacement at the elbow causes overestimation of nerve conduction velocity. We hypothesized that this overestimation may cause false-negative results when the American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) diagnostic criteria are used. METHODS:We investigated 9 ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22131

    authors: Won SJ,Yoon JS,Kim JY,Kim SJ,Jeong JS

    更新日期:2011-10-01 00:00:00

  • Serum CK, calcium, magnesium, and oxidative phosphorylation in mdx mouse muscular dystrophy.

    abstract::Serum creatine kinase (CK) activity, calcium (Ca) and magnesium (Mg) contents of skeletal muscle and isolated mitochondria, as well as oxidative phosphorylation of X-linked muscular dystrophic (mdx) mice were compared with normal control animals at ages 5, 10, and 23 weeks. Serum CK is elevated in mdx mice at all ages...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110809

    authors: Glesby MJ,Rosenmann E,Nylen EG,Wrogemann K

    更新日期:1988-08-01 00:00:00

  • Skeletal muscle expression of clathrin and mannose 6-phosphate receptor in experimental chloroquine-induced myopathy.

    abstract::Previous studies suggest that the muscle fiber lysosome system plays a central role in the increased formation of autophagosomes and autolysosomes that occurs in the context of chloroquine-induced myopathy. The goal of this study was to characterize the contribution of receptor-mediated intracellular transport, partic...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20288

    authors: Masuda T,Ueyama H,Nakamura K,Jikumaru M,Toyoshima I,Kumamoto T

    更新日期:2005-04-01 00:00:00

  • Lack of cold sensitivity in hyperkalemic periodic paralysis.

    abstract::The nosologic distinction between paramyotonia congenita and hyperkalemic periodic paralysis is somewhat blurred. Muscle membrane inexcitability induced by cooling seems to be characteristic of paramyotonia congenita. The effect of cooling on the maximal compound muscle action potential (CMAP) in patients with paramyo...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880090804

    authors: Subramony SH,Wee AS,Mishra SK

    更新日期:1986-10-01 00:00:00

  • Distal sensory nerve conduction of the superficial peroneal nerve: new method and its clinical application.

    abstract::The superficial peroneal nerve subserves sensation on the entire surface of the dorsum of the foot, except in small areas. All previously reported techniques for evaluating nerve conduction along this nerve tested a proximal portion of the nerve. We report a new method for evaluating sensory nerve conduction of the fo...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/mus.1056

    authors: Oh SJ,Demirci M,Dajani B,Melo AC,Claussen GC

    更新日期:2001-05-01 00:00:00

  • The influence of skeletal muscle reinnervation on experimentally induced myotonia.

    abstract::Earlier studies have shown that prior denervation of muscle prevents myotonia induced by 2,4-dichlorophenoxy acetic acid (2,4-D) both in vivo and in vitro. This work studied the effect of reinnervation on 2,4-D myotonia. Twenty Sprague-Dawley rats were injected with 2,4-D at specific intervals following unilateral sci...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880090414

    authors: Al-Sulaiman A,Al-Rajeh S,Iyer V

    更新日期:1986-05-01 00:00:00

  • Inflammatory processes in amyotrophic lateral sclerosis.

    abstract::Neuroinflammation is a characteristic of pathologically affected tissue in several neurodegenerative disorders. These changes can be observed in the brainstem and spinal cord of amyotrophic lateral sclerosis (ALS) cases and in mouse models of the disease. They include an accumulation of large numbers of activated micr...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.10191

    authors: McGeer PL,McGeer EG

    更新日期:2002-10-01 00:00:00

  • Confocal analysis of the dystrophin protein complex in muscular dystrophy.

    abstract::The dystrophin protein complex (DPC), composed of at least 10 proteins that associate with dystrophin, is critical for the maintenance of normal muscle fiber structure and physiology. In this study, we used immunohistochemistry and confocal microscopy to examine the relative abundance and distribution of several of th...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/1097-4598(200102)24:2<262::aid-mus120>3.0.

    authors: Draviam R,Billington L,Senchak A,Hoffman EP,Watkins SC

    更新日期:2001-02-01 00:00:00

  • Hexosaminidase A activity and amyotrophic lateral sclerosis.

    abstract::Abnormalities of GM2 ganglioside metabolism owing to hexosaminidase A (Hex A) deficiency have been associated with ALS phenotypes. The clinical features described in these ALS patients with Hex A deficiency include early onset, positive family history, and/or long disease duration. In an attempt to determine prospecti...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110307

    authors: Gudesblatt M,Ludman MD,Cohen JA,Desnick RJ,Chester S,Grabowski GA,Caroscio JT

    更新日期:1988-03-01 00:00:00

  • Analysis of the organophosphate-induced electromyographic response to repetitive nerve stimulation: paradoxical response to edrophonium and D-tubocurarine.

    abstract::We studied the mechanism underlying acute organophosphate intoxication (OPI) through in-vivo and in-vitro electrophysiologic studies in rats injected with diisopropylfluorophosphate. Intoxicated rats showed weakness, repetitive compound muscle action potentials (CMAPs) in response to a single stimulus, and decremental...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880141207

    authors: Maselli RA,Soliven BC

    更新日期:1991-12-01 00:00:00

  • Response to exercise of patients with idiopathic hyper-CK-emia.

    abstract::Patients with an idiopathic increase in serum creatine kinase (CK) levels (hyper-CK-emia) have a benign prognosis, but symptoms may be disabling in daily life. Previous studies have suggested that physical exercise increases the severity of complaints in these patients. We studied whether maximal and submaximal bouts ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.10232

    authors: Reijneveld JC,Te Boekhorst BC,Zonderland ML,Kalmijn S,Notermans NC

    更新日期:2002-12-01 00:00:00

  • Disruption and reorganization of sodium channels in experimental allergic neuritis.

    abstract::The axonal distribution of voltage-dependent Na+ channels was determined during inflammatory demyelinating disease of the peripheral nervous system. Experimental allergic neuritis was induced in Lewis rats by active immunization. In diseased spinal roots Na+ channel immunofluorescence at many nodes of Ranvier changed ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199808)21:8<1019::aid-mus6

    authors: Novakovic SD,Levinson SR,Schachner M,Shrager P

    更新日期:1998-08-01 00:00:00

  • Nemaline body myopathy caused by a novel mutation in troponin T1 (TNNT1).

    abstract:INTRODUCTION:Nemaline myopathy is a rare disorder characterized by skeletal muscle weakness of varying severity and onset, with the presence of nemaline rods on muscle biopsy. Congenital nemaline body myopathy due to mutations in TNNT1 has hitherto only been described as a result of a single founder mutation in patient...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24885

    authors: Abdulhaq UN,Daana M,Dor T,Fellig Y,Eylon S,Schuelke M,Shaag A,Elpeleg O,Edvardson S

    更新日期:2016-04-01 00:00:00

  • Biochemical functioning of mitochondria in normal and denervated mammalian skeletal muscle.

    abstract::Mitochondrial preparations derived from denervated rat skeletal muscle and paired control muscle are characterized with respect to their oxidative and phosphorylative capacities. Our data indicate that there is an impairment within the first 2 energy coupling regions of the respiratory chain and within the ATPase comp...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880040608

    authors: Joffe M,Savage N,Isaacs H

    更新日期:1981-11-01 00:00:00

  • Neural hyperexcitability in hyperkalemic periodic paralysis.

    abstract::An electrophysiologic study of peripheral nerve excitability was performed in patients with hyperkalemic periodic paralysis (HPP) and in normal controls. It was found that a marked degree of neural hyperexcitability existed in all patients with HPP who showed cold sensitivity. The results suggest involvement of the ne...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880020402

    authors: Segura RP,Petajan JH

    更新日期:1979-07-01 00:00:00

  • Influence of limb position on assessment of nerve mechanical properties by using shear wave ultrasound elastography.

    abstract:INTRODUCTION:Evaluation of nerve mechanical properties has the potential to improve assessment of nerve impairment. Shear wave velocity, as measured by using shear wave (SW) ultrasound elastography, is a promising indicator of nerve mechanical properties such as stiffness. However, elucidation of external factors that ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26842

    authors: Rugel CL,Franz CK,Lee SSM

    更新日期:2020-05-01 00:00:00

  • Adenosine inhibits depolarization-induced Ca(2+) release in mammalian skeletal muscle.

    abstract::In normal skeletal muscle, prolonged stimulation results in some cellular adenosine triphosphate (ATP) being converted to adenosine monophosphate (AMP) and then deaminated to inosine monophosphate (IMP). Here, we investigate whether the build-up of IMP contributes to muscle fatigue and also determine what happens if A...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199912)22:12<1674::aid-mus

    authors: Blazev R,Lamb GD

    更新日期:1999-12-01 00:00:00

  • Absence of developmental and unconventional myosin heavy chain in human suprahyoid muscles.

    abstract:INTRODUCTION:Contradictory reports of the myosin heavy chain (MHC) composition of adult human suprahyoid muscles leave unresolved the extent to which these muscles express developmental and unconventional MHC. METHODS:By immunohistochemistry, separation sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PA...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23946

    authors: Luo Q,Douglas M,Burkholder T,Sokoloff AJ

    更新日期:2014-04-01 00:00:00

  • Effect of spinal cord TRH deficiency on lower motorneuron function in the rat.

    abstract::Thyrotropin-releasing hormone (TRH), present in high concentrations in the mammalian spinal cord, exerts excitatory effects on the alpha-motorneuron (AMN) via axodendritic contacts. We used the neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) to deplete TRH from the ventral horn of the spinal cord of adult rats to determi...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880100504

    authors: Van den Bergh P,Kelly JJ Jr,Adelman L,Munsat TL,Jackson IM,Lechan RM

    更新日期:1987-06-01 00:00:00

  • Function of death-associated protein 1 in proliferation, differentiation, and apoptosis of chicken satellite cells.

    abstract:INTRODUCTION:Muscle growth and regeneration are processes closely associated with proliferation, differentiation, and apoptosis of muscle cells. Death-associated protein 1 (DAP1) has been identified as a negative regulator of autophagy. Little is known about the function of DAP1 in the regulation of myogenesis and sate...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23832

    authors: Shin J,McFarland DC,Strasburg GM,Velleman SG

    更新日期:2013-11-01 00:00:00

  • Basal lamina and superfast myosin expression in regenerating cat jaw muscle.

    abstract::We investigated the possible role of extracellular matrix in specifying the expression of superfast myosin during cat jaw muscle regeneration. Equal proportions of muscle tissue from jaw and limb were minced together after killing cellular elements from one source. We allowed the mince to regenerate in the bed of a fa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880140503

    authors: Hoh JF,Hughes S

    更新日期:1991-05-01 00:00:00

  • Expression of genes related to myostatin signaling during rat skeletal muscle longitudinal growth.

    abstract::In this study we investigated the gene expression of proteins related to myostatin (MSTN) signaling during skeletal muscle longitudinal growth. To promote muscle growth, Wistar male rats were submitted to a stretching protocol for different durations (12, 24, 48, and 96 hours). Following this protocol, soleus weight a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21426

    authors: Aoki MS,Soares AG,Miyabara EH,Baptista IL,Moriscot AS

    更新日期:2009-12-01 00:00:00

  • Guidelines for ethical behavior relating to clinical practice issues in neuromuscular and electrodiagnostic medicine.

    abstract::The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) developed guidelines to formalize the ethical standards that neuromuscular and electrodiagnostic (EDx) physicians should observe in their clinical and scientific activities. Neuromuscular and EDx medicine is a subspecialty of medicine that ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24910

    authors: Abel NA,De Sousa EA,Govindarajan R,Mayer MP,Simpson DA

    更新日期:2015-12-01 00:00:00

  • Real-time ultrasound imaging of muscles.

    abstract::A prospective study was done on 222 consecutive new patients referred to our pediatric muscle clinic to assess the diagnostic value of ultrasound imaging. Ultrasound scans were interpreted without knowledge of clinical presentation or results of other tests. Muscular dystrophy produced a brightly speckled pattern of i...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110110

    authors: Heckmatt JZ,Pier N,Dubowitz V

    更新日期:1988-01-01 00:00:00