Abstract:
:The extent to which a diagnostic observation or test contributes to a diagnosis is usually represented by a conditional, or Bayesian, probability. According to information theory, the contribution of a diagnostic observation can also be measured in bits of information. This offers a representation of the Bayes rule which may be useful in comparing and evaluating diagnostic sequences, since the diagnostic contributions of the various tests, expressed as bits of information, are additive, providing a simple and graphic representation of the diagnostic process.
journal_name
Ann Clin Lab Scijournal_title
Annals of clinical and laboratory scienceauthors
Johnson HAsubject
Has Abstractpub_date
1989-09-01 00:00:00pages
323-31issue
5eissn
0091-7370issn
1550-8080journal_volume
19pub_type
杂志文章abstract::Diabetes-induced hyperglycemia has a direct damaging effect on ovarian function. Despite its deadly impact on ovaries, the mechanism of this condition has not been fully elucidated. Glucose transporters are involved in glucose uptake and utilization. Many transporters have been detected in the ovaries, but their roles...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2019-11-01 00:00:00
abstract::Absorbed lead continuously adds to the lead deposited in the vascularized circumpulpal dentin of the teeth. Thus, this dental tissue is expected to contain a lead concentration which reflects the integrated lead exposure during the time from completion of tooth formation to tooth extraction or shedding. A method has b...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1984-07-01 00:00:00
abstract::A considerable variabilility in the effects of sample handling on NK cytotoxicity has been observed. Using flow cytometry, NK cytotoxicity assays and lymphocyte subset analysis of Ficoll-Hypaque-separated peripheral blood mononuclear cells (PBMCs) isolated from whole blood stored under various conditions were performe...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2013-07-01 00:00:00
abstract:CONTEXT:Myotonic dystrophies (DMs) are a group of autosomal dominant neuromuscular disorders which are caused by large CTG/CCTG-repeat expansions in untranslated regions of DMPK/ZNF9 gene. The "phenotypic overlap" in DMs creates complication in distinguishing patients with DM1 from patients with DM2 and underscores the...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2015-10-01 00:00:00
abstract::Mucoepidermoid carcinoma of the lung is exceedingly rare. Our case involves a 58-year-old male who presented with shortness of breath, dysphagia, and weight loss. He denied ever smoking. Chest x-ray revealed trapped lung, and CT demonstrated a right bronchial mass. Diagnosis of lung carcinoma was made by bronchoscopic...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00
abstract::Histologic sections of thyroid glands resected from 12 patients with Hashimoto's thyroiditis have been studied in which areas were present showing clear nuclear changes such as those seen in papillary carcinoma. The patients' ages ranged from 28 to 78 years (mean = 57.3); 11 were women and one was a man. The lesions p...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::Small marker chromosomes (SMC) associated with severe Turner syndrome (TS) variants often represent reduced X chromosomes lacking the X inactivation center (XIC), perturbed dosage compensation, and unbalanced gene expression. A TS patient with mental retardation (MR), unusually short stature, facial and limb malformat...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::The bioassay system from American Diagnostic for amikacin was compared to the same company's radioimmunoassay (RIA) technique used in this hospital. The bioassay is performed by adding serum from a patient to wells cut in agar which have been seeded with a susceptible fast growing microorganism (Enterobacter). After i...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1981-09-01 00:00:00
abstract::Neuropeptide modulation of hematopoietic stem cell differentiation was studied in an in vitro murine system. Endorphins were able to influence the erythropoietin-dependent differentiation of bone marrow cells into erythroid colony forming units in a dose dependent manner. The effects on progenitor cell maturation were...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1987-09-01 00:00:00
abstract::The present study applies the approach described in Mark et al. for the testing of toxic chemicals produced during the drying of Douglas-fir. The genotoxic potential of Douglas-fir condensate has been previously unexplored and is thus an area of appropriate concern to the forest products industry, regulatory, agencies...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract::We previously reported that proper dilution of sera that contain IgG monoclonal proteins (M-proteins) is necessary for accurate quantitation of serum albumin and M-protein concentrations separated by serum protein electrophoresis (SPE) using the Beckman PARAGON agarose electrophoresis system. We now report the signifi...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract::Hydroxyethyl starch is commonly used as a plasma volume expander in the surgical patient. Although it is generally considered a safe plasma substitution, some reports of an acquired von Willebrand's disease-like syndrome have been documented. To examine this further, von Willebrand factor: ristocetin cofactor activity...
journal_title:Annals of clinical and laboratory science
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:Quality assurance of newly developed or manufactured blood grouping reagents with reagent red blood cells (RBCs) is crucial in the process of product approval by governmental agency. However, RBCs with rare blood group are not easily available in the fresh state. We investigated the feasibility of cryopreser...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2018-03-01 00:00:00
abstract::Gamma irradiation of blood is performed to prevent transfusion-associated graft-versus-host disease and can result in an accelerated efflux of intracellular potassium (K+). The oxygen content of the blood and the temperature at which the irradiation is carried out are two variables reported to affect this shift; they ...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::Intraventricular hemorrhage (IVH) and classical periventricular leukomalacia complex are considered the two most common forms of perinatal anoxic-ischemic brain injury. However, recently, a third entity, the periventricular leukomalacia complex (PLC) was described and was seen in 31 percent of 61 premature infants com...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::Von Willebrand factor (VWF) cleaving metalloprotease, ADAMTS13, known for its causative relation to thrombotic thrombocytopenic purpura (TTP), also decreases to variable degree in other clinical conditions associated with thrombocytopenia, indicating a possible contribution of moderate deficiency of ADAMTS13 to platel...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract::Increased red cell lipid peroxidation (LP) occurs in the presence of ionized iron, as well as with various heme moieties and other transition metal ions. In stored erythrocytes, the degree of LP, as determined by plasma malondialdehyde measurements, can be significantly reduced by the addition of various metal chelati...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Current changes of the healthcare environment have promoted the creation of chest pain centers in the emergency departments for rapid triage of patients admitted for cardiac evaluation. Because of the inefficiency of electrocardiogram for the diagnosis of acute myocardial infarction, blood cardiac markers play an impo...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract::Male Sprague-Dawley rats were subjected for 2 weeks to daily injections of homocysteine (Hcy), which increased plasma Hcy approximately 2-fold. Echocardiography indicated significant increases in left ventricular diastolic (13%) and systolic (31%) dimensions and decreases in posterior wall thickness (diastolic, -17%; ...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract::The utilization of fibrin sealants to augment hemostasis, seal tissues, and facilitate targeted delivery of drugs is increasing. In 1985, a hospital-based program was established to provide autologous and allogeneic cryoprecipitate that serves as a fibrin sealant when combined with bovine thrombin. To date, more than ...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章,评审
doi:
更新日期:2001-01-01 00:00:00
abstract::Serum transient paraproteins are small monoclonal immunoglobulins that are induced by a self-limiting regulatory defect in the control of certain terminally differentiated B-cell clones. Relatively uncommon and ill-defined in the medical literature, such proteins may be regarded as immunologic anomalies. Their clinica...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract::People of the Jehovah's Witness faith believe that they shall "abstain from blood." Because of this belief, we encounter the challenges from Jehovah's Witness patients who actively seek medical care for themselves and their children, but refuse the transfusion of blood products, which may result in increased morbidity...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2016-12-01 00:00:00
abstract:GOALS:This study aims to examine the effects of raising the reporting age for benign endometrial cells (BEC) on Papanicolaou (Pap) tests according to the 2014 3rd edition of the Bethesda System for Cervical Cytology, as well as the sequelae of the 2012 American Society of Colposcopy and Cervical Pathology (ASCCP) guide...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2017-05-01 00:00:00
abstract::Fractionation of serum alkaline phosphatase by either biochemical or electrophoretic techniques is often insufficient to determine the source of the elevated serum enzyme. In 31 unselected patients with high serum alkaline phosphatase a simultaneous determination of serum gamma glutamyl transpeptidase and urinary hydr...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1978-03-01 00:00:00
abstract:OBJECTIVES:An increasing number of studies have pointed out the side effects of valproic acid (VPA), an antiepileptic drug used for the treatment of seizures in children and adults. The aim of this study is to evaluate whether VPA interferes with oxidative metabolism in the heart and whether edaravone, the novel free r...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2015-04-01 00:00:00
abstract::Degenerative joint disease (DJD) is characterized by pain on use. X-rays show cartilage narrowing and osteophytes. Synovial effusions are non-inflammatory, i.e. clear wiht good viscosity and less than 2000 WBC per mm. 3 Cartilage fragments may be seen in the joint fluid. Important systemic diseases that can cause dege...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1975-07-01 00:00:00
abstract:BACKGROUND:Various assays for detecting high-risk human papillomavirus (HR HPV) have been introduced recently, including the Abbott RealTime High-Risk HPV assay. We sought to compare the performance of Abbott PCR to Hybrid Capture 2 for the detection of HR HPV. METHODS:A total of 941 cervical swab specimens were obtai...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2016-09-01 00:00:00
abstract::A 55-year-old Korean woman was initially diagnosed with acute myelomonocytic leukemia (AML). After induction chemotherapy was performed using cytarabine, idarubicin, and G-CSF, complete remission (CR) was subsequently achieved following reinduction chemotherapy using the same chemotherapeutic agents. Thirty-six months...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
abstract::The erythrocyte abnormality most often associated with the toxic effects of commonly used drugs is premature destruction. The mechanisms of erythrocyte destruction include: denaturation of unstable hemoglobins, oxidation of sulfhydril groups in hemoglobin and the erythrocyte membrane in the presence of glucose-6-phosp...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章,评审
doi:
更新日期:1988-01-01 00:00:00
abstract::We report a case of a 69-yr-old previously healthy man with acute spontaneous Achilles tendon rupture and severe tendonitis, which occurred after 2 weeks of steroid therapy for newly diagnosed giant cell arteritis. The Achilles tendon rupture was treated conservatively and the tendonitis resolved incrementally with st...
journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00