Abstract:
OBJECTIVES:The association between body mass index (BMI) and oral diseases was investigated, and levels of obesity-related inflammatory mediators were evaluated. SUBJECTS AND METHODS:Participants (n = 160) were clinically and radiographically examined for oral diseases. Blood profiles were recorded. Levels of adiponectin, leptin, and C-reactive protein (CRP) were measured. RESULTS:One hundred and thirteen (70.6%) participants had overweight or obese status (BMI ≥ 23.0 kg/m2 ). Sum of dental diseases and severe periodontitis were higher in overweight or obese individuals than in normal-weight participants (p = .037 and p = .002, respectively). A significant difference in oral mucosal disorders between normal weight and overweight or obesity was not found. Plasma leukocyte counts, liver enzymes, leptin, and CRP levels were increased while adiponectin levels were decreased in individuals with BMI≥23.0 kg/m2 compared with normal-weight participants. After adjusting for age, sex, fasting plasma glucose level, smoking, and exercise, obesity was associated with sum of dental diseases (ß = 0.239, p = .013), severe periodontitis (OR=4.52; 95% CI 1.37, 14.95, p = .013), adiponectin (ß = -0.359, p < .001), leptin (ß = 0.630, p < .001), and CRP levels (OR=12.66; 95% CI 3.07, 52.21, p < .001). CONCLUSION:Overweight or obese Thai people were related to an increase in inflammatory dental and periodontal diseases with an altered health profile and plasma inflammatory mediators.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Thanakun S,Pornprasertsuk-Damrongsri S,Izumi Ydoi
10.1111/odi.12679subject
Has Abstractpub_date
2017-10-01 00:00:00pages
956-965issue
7eissn
1354-523Xissn
1601-0825journal_volume
23pub_type
杂志文章相关文献
ORAL DISEASES文献大全abstract:INTRODUCTION:Clastic cells, originating from the monocyte-macrophage lineage, resorb mineralized tissues. In periapical periodontitis, alveolar bone around the tooth apex becomes resorbed; however, the roots of the teeth are often left intact by yet unknown mechanisms. Here, we examined the status of clastic cells in a...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12824
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To analyze and compare periodontal parameters in chronic renal failure (CRF) patients undergoing peritoneal dialysis (PD) therapy with a group of patients on hemodialysis (HD) treatment and healthy controls (C). PARTICIPANTS:Seventy-five PD patients (mean age: 44 +/- 12 years) were matched with 41 HD patient...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2007.01372.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:Fourier Transform Infrared microspectroscopy let characterize the macromolecular composition and distribution of tissues and cells, by studying the interaction between infrared radiation and matter. Therefore, we hypothesize to exploit this analytical tool in the analysis of inflamed pulps, to detect the dif...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12635
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Tobacco-related oral squamous cell carcinoma (OSCC) is one of the most common cancers involving Indian males. We assessed the association of IL4 promoter -589 T>C, -33 T>C, and IL6-174 G>C functional genetic polymorphisms with tobacco-related OSCC in Asian Indians. PATIENTS AND METHODS:The IL4 and IL6 promo...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2011.01831.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:CD10 is expressed on the majority of follicle-center lymphomas and Burkitt lymphomas. CD10 has also been shown to be present in a variety of other neoplasms. DESIGN:The aim of this study was a correlation of CD10 and several parameters: age, tumor size, presence of lymph node metastases, clinic stage, histol...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2005.01196.x
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVES:To evaluate clinical, demographic, and histopathological characteristics of pigmented lesions of the oral mucosa. MATERIALS AND METHODS:A cross-sectional study was conducted over a 64-year period. Information was collected from medical charts, and all archived histopathological specimens with diagnoses of a...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12924
更新日期:2018-11-01 00:00:00
abstract::Plasmablastic lymphoma (PBL) has been recently characterised as an aggressive subtype of non-Hodgkin's lymphoma, most frequently arising in the oral cavity of HIV-infected patients. To date, approximately 60 cases fulfilling the clinico-pathological characteristics of PBL have been reported. PBLs are composed of large...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1601-0825.2008.01493.x
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:The early diagnosis and monitoring of Crohn's disease (CD) and orofacial granulomatosis (OFG) might be facilitated by assaying potential disease biomarkers in saliva. Markers of oxidative stress and inflammation were assayed in salivas from patients with CD, OFG and concurrent OFG and CD (OFG + CD). SUBJECT...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13537
更新日期:2021-03-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate the prevalence of areca nut consumption and to identify social and behavioural determinants among a Taiwanese adolescent population. SUBJECTS AND METHODS:A random sample of 5,343 high school students aged between 15-18 years in Kaohsiung, Taiwan, participated in the study. Par...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13467
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:Secretory leukocyte proteinase inhibitor (SLPI) is an endogenous mucosa associated protein that has been proposed to possess anti-human immunodeficiency virus type 1 (HIV-1) activity. The aim of this study was to investigate the biological function of SLPI in salivary mediated inhibition of HIV infection and ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1034/j.1601-0825.2002.01807.x
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVES:The aim was to investigate the attitudes of people with HIV infection towards their own dental care provision and the possible implications for future resource allocation. DESIGN:Sixty-nine HIV positive subjects attending support groups in London were interviewed. Past and current dental visiting behaviour,...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.1998.tb00250.x
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Increasing evidence indicates that andrographolide (ADG) exhibits anti-cancer activity against various cancer cell lines. However, its high hydrophobicity and poor bioavailability restrict its clinical application as a chemopreventative agent. Previously, we have shown that ADG-loaded solid lipid nanoparticl...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13751
更新日期:2020-12-09 00:00:00
abstract:OBJECTIVE:To investigate the prevalence of dental pain among adolescent students and its association with individual, school and city variables, using a multilevel approach. SUBJECTS AND METHODS:Individual and school data were obtained from the National Adolescent School-Based Health Survey (PeNSE) conducted in Brazil...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13100
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:The imbalanced host response in front of a dysbiotic biofilm is one of the major aspects of severe periodontitis, which also presents a strong familial aggregation related to the susceptibility factors transmission within family members. This study hypothesized that aggressive periodontitis (GAgP) patients a...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13738
更新日期:2020-11-30 00:00:00
abstract:OBJECTIVES:Oral lichen planus is a chronic, T-cell-mediated, inflammatory disease that affects the oral cavity. The oral lichen planus pathogenesis is still unclear, however, the main evidence is that the mechanisms of activation of different T lymphocyte pathway induce apoptosis with an increase in Th1 and Th17 subtyp...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12837
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:Orthodontic-induced external apical root resorption (EARR) is a complex phenotype determined by poorly defined mechanical and patient intrinsic factors. The aim of this work was to construct a multifactorial integrative model, including clinical and genetic susceptibility factors, to analyze the risk of devel...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12185
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To assess the effect of adjunctive use of modified cold-atmospheric pressure plasma (MCAP) to surgically mechanical debridement (MD) on peri-implantitis (PI) in beagles. MATERIAL AND METHODS:Bilateral mandibles of beagles with PI, which induced by cotton ligature twined with steel in sub-marginal around the ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13757
更新日期:2020-12-15 00:00:00
abstract:OBJECTIVE:The examination of prophylactic efficacy of tretinoin on oral mucositis, post bone marrow transplantation (BMT). PATIENTS AND METHODS:The study population consisted of 11 patients undergoing BMT. Six tretinoin topically-treated patients (0.25 mg daily of 0.1% tretinoin cream) were matched with five non-treat...
journal_title:Oral diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1601-0825.1997.tb00049.x
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to establish a possible association between the degree of differentiation of squamous cell carcinomas (SCC) derived from rat oral tissues treated in vivo with carcinogen 4NQO, and the expression of TGF-beta on epithelial cells and the distribution of extracellular matrix proteins (la...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.1996.tb00198.x
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:For clinical applications of biomarkers, there is a need for multiplex assays using high throughput platforms. The objective of this study was to determine the efficacy of Luminex Multianalyte Profiling (xMAP) technology for measurement of salivary proteins and to evaluate whether multiplex assays are as effe...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2008.01488.x
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:Characterize the cell profile and immunostaining of proinflammatory markers in an experimental model of bisphosphonate-related osteonecrosis of the jaw (BRONJ). MATERIALS AND METHODS:Male Wistar rats (n = 6-7) were treated chronically with saline solution or zoledronic acid (ZA) at 0.04, 0.20, and 1.00 mg k...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12513
更新日期:2016-10-01 00:00:00
abstract::In order for chairside diagnostic testing to make an impact on dental therapy, practitioners require a better understanding of genetic mutations contributing to the pathophysiology of periodontal disease. Commensal and pathogenic bacterial colonization in oral cavity tissues produces a cascade of proinflammatory signa...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.13030
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Opinions, knowledge, behaviours and attitudes of general dental practitioners on oral cancer prevention and detection have been reported from many countries. However, experiences and skills of oral cancer detection have not been evaluated systematically. OBJECTIVE:To obtain information on behaviours of scre...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2005.01225.x
更新日期:2006-09-01 00:00:00
abstract:AIM:The present study aimed to monitor the clinical outcomes and the metabolic response of periodontal therapy (non-surgical) in patients with periodontitis (chronic) and uncontrolled diabetes (type 2). METHODS:Eighty-eight subjects with periodontitis (chronic) and uncontrolled diabetes (type 2) were enrolled in this ...
journal_title:Oral diseases
pub_type: 杂志文章,随机对照试验
doi:10.1111/odi.13256
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:We determined the correlation between saliva and serum for CA125 and leptin, and evaluated their clinical screening potential for parotid tumours. SUBJECTS AND METHODS:Serum, acid-stimulated bilateral parotid saliva and chewing-stimulated whole saliva were collected and measured the levels of CA125 and lept...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12505
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the antitumor effects of fusion protein hGrB-TV of human granzyme B (hGrB) and truncated vascular endothelial growth factor (tVEGF) on human oral squamous cell carcinoma (OSCC) in vitro and in vivo. METHODS:The fusion protein hGrB-TV was expressed and purified from E. coli bacteria by affinity ch...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12522
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine any association between anxiety and salivary cortisol levels in oral lichen planus (OLP) patients by the case-control method. DESIGN RELEVANT: Forty patients with OLP were evaluated. The OLP diagnosis was established through a composite of accepted clinical and histopath...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1034/j.1601-0825.2003.00960.x
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVE:We investigated the relationship amongst the oral mucosal bacterial community, clinical severity and inflammatory markers in the two most common immune-mediated oral mucosal diseases, namely recurrent aphthous stomatitis (RAS) and oral lichen planus (LP). METHODS:Patients with RAS (n = 15) and LP (n = 18) an...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13420
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:To obtain baseline information on the prevalence of oral problems and disease in institutionalized elderly in a Scottish hospital. DESIGN:A cross-sectional clinical investigation with complementary microbiological studies as appropriate. SUBJECTS AND METHODS:A cohort of 147 elderly in five long-term care wa...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.1995.tb00177.x
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVE:Osteoblast apoptosis is critical for the development and repairing of bone destruction in persistent apical periodontitis (PAP). Enterococcus faecalis is considered as a frequently isolated pathogen of PAP. This study aimed to explore the effect of E. faecalis on apoptosis in osteoblastic MC3T3-E1 cells via a...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12883
更新日期:2019-01-01 00:00:00