Abstract:
OBJECTIVE:The examination of prophylactic efficacy of tretinoin on oral mucositis, post bone marrow transplantation (BMT). PATIENTS AND METHODS:The study population consisted of 11 patients undergoing BMT. Six tretinoin topically-treated patients (0.25 mg daily of 0.1% tretinoin cream) were matched with five non-treated control patients comparing mucositis severity, duration and analgetic (morphine) requirements. Concomitant follow-up included conditioning parameters associated with mucositis and engraftment. RESULTS:The mean of oral mucositis peak scores was significantly lower in the tretinoin-treated patients vs the non-treated patients (score 1.5 vs 3.6; P < 0.02). In the majority of cases the duration of the most severe phase of oral mucositis was shorter in the tretinoin-treated group as compared with the control. Only one patient in the experimental group required morphine analgesics compared with four patients in the control group. CONCLUSIONS:This preliminary study indicates that the severity of oral mucositis, both objective and subjective, in BMT patients may be reduced by 0.1% topical tretinoin cream, 0.25 mg, administered daily from the beginning of the BMT conditioning regimen until marrow engraftment.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Cohen G,Elad S,Or R,Galili D,Garfunkel AAdoi
10.1111/j.1601-0825.1997.tb00049.xsubject
Has Abstractpub_date
1997-12-01 00:00:00pages
243-6issue
4eissn
1354-523Xissn
1601-0825journal_volume
3pub_type
临床试验,杂志文章,随机对照试验相关文献
ORAL DISEASES文献大全abstract:OBJECTIVE:To examine whether transient receptor potential vanilloid 2 (TRPV2) contributes to the changes in intra-oral thermal and mechanical sensitivity following the incision of buccal mucosa. MATERIALS AND METHODS:Buccal mucosal pain threshold was measured after the incision. Changes in the number of TRPV2-immunore...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12853
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:We examined the influence of in vitro aging on Campylobacter rectus (C. rectus) lipopolysaccharide (LPS)-stimulated prostaglandin (PG), E2 release frOm human gingival fibroblasts (HGFs). MATERIALS AND METHODS:LPS was prepared from C. rectus ATCC33238. HGFs were established from healing gingival tissue remove...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.1996.tb00225.x
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the effectiveness of aloe vera containing herbal dentifrices in improving plaque control and gingival health. METHODS:A manual and electronic literature (MEDLINE and Cochrane Central Register of Controlled Trials) search was performed up to July 2012, for randomized controlled trials presenting ...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.12113
更新日期:2014-04-01 00:00:00
abstract::The aim of this study was to assess the prevalence of factors associated with oral colonization by Candida spp. in pediatric patients with AIDS. The sample comprised of 117 children. Clinical status, medicines in use, and laboratory findings were obtained from hospital records; sociodemographic data were given by rela...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2010.01765.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:Prognosis of patients with head and neck squamous cell carcinoma (HNSCC) is still poor. Novel therapeutic approaches are of great interest to improve the effects of radiochemotherapy. We evaluated the effects of tyrosine kinase inhibitor neratinib on HNSCC cell lines CAL27, SCC25 and FaDu as a single agent an...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12552
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:Orthodontic-induced external apical root resorption (EARR) is a complex phenotype determined by poorly defined mechanical and patient intrinsic factors. The aim of this work was to construct a multifactorial integrative model, including clinical and genetic susceptibility factors, to analyze the risk of devel...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12185
更新日期:2014-10-01 00:00:00
abstract::Apical periodontitis (AP) is a prevalent infectious and inflammatory disorder that involves inflammation of periapical tissues and the disintegration of alveolar bone. AP may eventually lead to tooth loss if not timely treated. This disease is caused by pathogenic bacteria in the necrotic pulps and root canals, thereb...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.13450
更新日期:2020-06-02 00:00:00
abstract:UNLABELLED:Abnormalities in the p53 gene are regarded as the most consistent genetic abnormalities detected in head and neck squamous cell carcinogenesis. Two new members of the p53 gene family, p73 at the 1p36 region and p63 at the 3q27-29 region, have recently been identified. They share considerable sequence homolog...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1034/j.1601-0825.2003.02920.x
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to evaluate the prevalence and distribution of oral lesions (OLs) in Turkish population. SUBJECTS AND METHODS:In this cross-sectional study, 765 residents (F/M: 375/390) were selected by the cluster sampling method and examined according to WHO criteria. RESULTS:Excessive mela...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2004.01062.x
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVES:To determine glucose transporter 1 (GLUT1) and runt-related transcription factor 2 (RUNX2) expression during reparative dentinogenesis after pulpotomy with mineral trioxide aggregate (MTA) capping. SUBJECTS AND METHODS:Eight-week-old male Wistar rats were used. Pulp of the upper left first molar was exposed...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13230
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:Radicular cysts occur as a result of the immunological response to continuous antigenic stimulation from root canals. We correlated the immunophenotypical composition of the lymphoid infiltrate to the microvessel density expressed by the count of CD34 reactive endothelial cells in radicular cysts. SUBJECTS A...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2012.01961.x
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:To investigate practices and opinions of general dentists in Maryland, USA, related to oral and pharyngeal cancer prevention and early detection. DESIGN AND METHODS:A pre-tested, 34-item questionnaire, cover letter and addressed, stamped envelope were mailed in the summer, 1995, to a simple random sample of...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2000.tb00140.x
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To investigate the therapeutic effect of oral glucosamine (GS) as an adjunct to hyaluronic acid (HA) injection on patients with temporomandibular joint osteoarthritis (TMJ OA). METHODS:In this clinical trial, 136 participants, diagnosed as TMJ OA clinically and radiographically, were enrolled and randomized ...
journal_title:Oral diseases
pub_type: 杂志文章,随机对照试验
doi:10.1111/odi.12760
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To determine the impact of highly active antiretroviral therapy (HAART) on salivary gland function in human immunodeficiency virus (HIV) positive women from the Women's Interagency HIV Study (WIHS). DESIGN:Longitudinal cohort study. SUBJECTS AND METHODS:A total of 668 HIV positive women from the WIHS cohort...
journal_title:Oral diseases
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1601-0825.2008.01456.x
更新日期:2009-01-01 00:00:00
abstract:AIM:To evaluate the role of baseline neutrophil-to-lymphocyte ratio (NLR) as prognostic marker in squamous cell carcinoma of the oropharynx (OPC) treated with definitive chemoradiotherapy (CRT) in the era of HPV status. PATIENTS AND METHODS:A retrospective analysis of 125 patients (pts) affected with locally advanced ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13366
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:Orofacial granulomatosis (OFG) is a rare condition characterized by non-caseating granulomas in the orofacial region. Protease-Activated Receptors (PARs) play a role in inflammatory diseases in diverse human tissues. The aim of the study was to investigate the expression of PAR-1, PAR-2, MMP-2, MMP-9, COX-1, ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2006.01317.x
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:This article sets out to evaluate the prevalence and aetiopathogenesis of edentulism in patients on haemodialysis. SUBJECTS AND METHODS:The study group comprised 44 adult patients with end-stage renal disease (ESRD) on haemodialysis. A control group was formed of 44 individuals matched for age and sex and wi...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12486
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:To comparatively assess periodontal status in patients who chew different products and patients who do not have this habit and to assess how this practice interacts with predisposing factors and risk indicators of disease. METHODS:Patients included in the dental care carried out in a rural community in Indi...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12820
更新日期:2018-07-01 00:00:00
abstract::A wide spectrum of oral lesions has been associated with human immunodeficiency viral infection (HIV), or AIDS. This report describes the case of an HIV-infected patient who developed a case of disseminated sporotrichosis whose first clinical sign was the presence of orofacial lesions. A histopathological study of thi...
journal_title:Oral diseases
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:Cathepsin K was initially discovered as an osteoclast-specific cysteine proteinase, but the enzyme is also expressed in various cancers including oral squamous cell carcinomas. This study aimed to clarify the function of cathepsin K in oral squamous cell carcinomas. MATERIALS AND METHODS:Expression levels of...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12643
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Tobacco-related oral squamous cell carcinoma (OSCC) is one of the most common cancers involving Indian males. We assessed the association of IL4 promoter -589 T>C, -33 T>C, and IL6-174 G>C functional genetic polymorphisms with tobacco-related OSCC in Asian Indians. PATIENTS AND METHODS:The IL4 and IL6 promo...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2011.01831.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:To investigate tooth ultrastructure and mutation of two patients in a family affected with osteogenesis imperfecta (OI) type IV and dentinogenesis imperfecta (DGI). METHODS:Mutations were detected by whole exome and Sanger sequencing. The permanent second molar obtained from the proband (DGI1) and the prima...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13657
更新日期:2020-09-29 00:00:00
abstract:OBJECTIVE:For clinical applications of biomarkers, there is a need for multiplex assays using high throughput platforms. The objective of this study was to determine the efficacy of Luminex Multianalyte Profiling (xMAP) technology for measurement of salivary proteins and to evaluate whether multiplex assays are as effe...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2008.01488.x
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:Candida-induced denture stomatitis is a common debilitating problem among denture wearers. Previously, we described the fabrication of a new denture material that released antifungal drugs when immersed in phosphate buffered saline. Here, we use more clinically relevant immersion conditions (human saliva; 37°...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12456
更新日期:2016-07-01 00:00:00
abstract::The first World Workshop on Oral AIDS was held in San Diego in 1988, organized by John and Deborah Greenspan who saw the need and advantages of getting together all those health workers globally who were interested in oral aspects of HIV with a common purpose of advancing the field collectively and collaboratively. Si...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13385
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:As the era of aging comes, cognitive impairment (CI) is increasing. The impact of rehabilitation of lost tooth on CI remains unclear. This study aimed to investigate whether non-rehabilitated lost teeth (NRLT) is associated with CI among Korean elders. METHODS:A total of 280 elders comprising of 140 cases an...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12960
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To describe the clinical and genetic features of patients with cherubism. MATERIAL AND METHODS:A descriptive analysis of 14 cases from nine different families was carried out. Clinicopathological, imaging, and follow-up data were retrieved from patients' medical files and correlated with the genetic profile ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12705
更新日期:2017-11-01 00:00:00
abstract::The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry,...
journal_title:Oral diseases
pub_type: 历史文章,杂志文章,评审
doi:10.1111/j.1601-0825.2009.01538.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To develop a novel test for chronic ulcerative stomatitis (CUS), a chronic immunologically mediated condition that produces oral ulcerations. Current diagnostic methods require expensive and technically demanding in situ immunofluorescence (IF) studies. DESIGN:An Enzyme-Linked ImmunoSorbent Assay (ELISA) was...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2009.01606.x
更新日期:2010-03-01 00:00:00
abstract::Cannabis, also known as marijuana, is one of the most commonly used substances for medical and recreational purposes globally. With the trend of global legalization of medical use of cannabis and even the recreational use, the prevalence of recreational use of cannabis has increased markedly over the past few years. C...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.13246
更新日期:2020-10-01 00:00:00