Plasmablastic lymphoma: a review.


:Plasmablastic lymphoma (PBL) has been recently characterised as an aggressive subtype of non-Hodgkin's lymphoma, most frequently arising in the oral cavity of HIV-infected patients. To date, approximately 60 cases fulfilling the clinico-pathological characteristics of PBL have been reported. PBLs are composed of large cells with eccentrically located nuclei and deeply basophilic cytoplasm with a paranuclear hof. The tumour cells are invariably immunoreactive for the plasma cell marker CD138, and show monoclonal rearrangement of the immunoglobulin heavy chain gene (IgH) and/or clonal restriction of the Ig light chain (IgL) gene expression in most of the cases. Similar to other types of AIDS-related lymphomas, there is evidence that Epstein-Barr virus and Kaposi-sarcoma associated Human Herpes Virus 8 may play a relevant role in the pathogenesis of PBL. PBL patients have been treated heterogeneously, with a combination of chemotherapy, radiotherapy and/or surgery, and their prognosis is usually poor, with a death rate of approximately 60% at 1 year.


Oral Dis


Oral diseases


Rafaniello Raviele P,Pruneri G,Maiorano E




Has Abstract


2009-01-01 00:00:00














  • Deregulation of desmosomal proteins and extracellular matrix proteases in odontogenic keratocyst.

    abstract:OBJECTIVE:Odontogenic keratocyst (OKC) is a benign lesion that tends to recur after surgical treatment. In an attempt to clarify the molecular basis underlining the OKC pathobiology, we aimed to analyze its proteomic profile. MATERIALS AND METHODS:We compared the proteomic profiles of five OKC and matched normal oral ...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Diniz MG,Duarte-Andrade FF,Stussi F,Vitório JG,Fonseca FP,Ramos Domingues R,Paes Leme AF,Gomes CC,Gomez RS

    更新日期:2020-08-09 00:00:00

  • Mucoepidermoid carcinoma of minor salivary glands: a clinical study of 16 cases and review of the literature.

    abstract:OBJECTIVE:Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of salivary glands with a widely diverse biologic behavior that is correlated with the histological grade of the tumor. The purpose of this study was to evaluate the clinical outcomes of MEC of minor salivary glands in a group of 16 patients, w...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审


    authors: Triantafillidou K,Dimitrakopoulos J,Iordanidis F,Koufogiannis D

    更新日期:2006-07-01 00:00:00

  • Marathon of eponyms: 25 Yersiniosis.

    abstract::The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry,...

    journal_title:Oral diseases

    pub_type: 传,历史文章,杂志文章


    authors: Scully C,Langdon J,Evans J

    更新日期:2012-05-01 00:00:00

  • Multiplexed immunobead-based assay for detection of oral cancer protein biomarkers in saliva.

    abstract:OBJECTIVE:For clinical applications of biomarkers, there is a need for multiplex assays using high throughput platforms. The objective of this study was to determine the efficacy of Luminex Multianalyte Profiling (xMAP) technology for measurement of salivary proteins and to evaluate whether multiplex assays are as effe...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Arellano-Garcia ME,Hu S,Wang J,Henson B,Zhou H,Chia D,Wong DT

    更新日期:2008-11-01 00:00:00

  • Salivary secretion, mucin concentrations and Candida carriage in HIV-infected patients.

    abstract:OBJECTIVES:To test whether the submandibular/sublingual (SMSL) salivary secretion, mucin concentration and candida carriage status were altered in human immunodeficiency virus-positive (HIV+) patients. SUBJECTS AND METHODS:SMSL saliva collected from 48 HIV-infected and 31 HIV-negative men were analyzed for flow rates,...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Jainkittivong A,Lin AL,Johnson DA,Langlais RP,Yeh CK

    更新日期:2009-04-01 00:00:00

  • Pharmacodiagnostic evaluation of EGFR expression in oral squamous cell carcinoma.

    abstract:OBJECTIVE:To determine epidermal growth factor receptor (EGFR) expression in oral squamous cell carcinomas (OSCC), and its possible relationships with clinical findings, histological findings, disease course and prognosis. MATERIALS AND METHODS:Surgical specimens of 47 OSCCs were studied immunohistochemically for dete...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Diniz-Freitas M,García-Caballero T,Antúnez-López J,Gándara-Rey JM,García-García A

    更新日期:2007-05-01 00:00:00

  • Salivary proteomics in lichen planus: A relationship with pathogenesis?

    abstract:OBJECTIVES:Oral lichen planus is a chronic, T-cell-mediated, inflammatory disease that affects the oral cavity. The oral lichen planus pathogenesis is still unclear, however, the main evidence is that the mechanisms of activation of different T lymphocyte pathway induce apoptosis with an increase in Th1 and Th17 subtyp...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Souza MM,Florezi GP,Nico M,de Paula F,Paula FM,Lourenço SV

    更新日期:2018-07-01 00:00:00

  • Immunohistochemical correlation between microvessel density and lymphoid infiltrate in radicular cysts.

    abstract:OBJECTIVE:Radicular cysts occur as a result of the immunological response to continuous antigenic stimulation from root canals. We correlated the immunophenotypical composition of the lymphoid infiltrate to the microvessel density expressed by the count of CD34 reactive endothelial cells in radicular cysts. SUBJECTS A...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Zizzi A,Aspriello SD,Ferrante L,Stramazzotti D,Colella G,Balercia P,Lo Muzio L,Piemontese M,Goteri G,Rubini C

    更新日期:2013-01-01 00:00:00

  • MicroRNA-21 promotes orthodontic tooth movement by modulating the RANKL/OPG balance in T cells.

    abstract:OBJECTIVES:The present study was designed to investigate the effects of microRNA-21 (miR-21) on orthodontic tooth movement. METHODS:The orthodontic tooth movement model was established in C57BL/6 and miR-21-/- mice with or without implantation of activated T cells. Histological and histomorphometrical analyses were pe...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Wu L,Su Y,Lin F,Zhu S,Wang J,Hou Y,Du J,Liu Y,Guo L

    更新日期:2020-03-01 00:00:00

  • The heme oxygenase system and oral diseases.

    abstract::Oral Diseases (2011) 17, 252-257 Heme oxygenase (HO) system catabolizes heme into three products: carbon monoxide (CO), biliverdin/bilirubin and free iron, which consists of three forms identified to date: the oxidative stress-inducible protein HO-1 and the constitutive isozymes HO-2 and HO-3. HO has been involved in ...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审


    authors: Fan W,Huang F,Zhu X,Li D,Fu S,He H

    更新日期:2011-04-01 00:00:00

  • Effects of neratinib and combination with irradiation and chemotherapy in head and neck cancer cells.

    abstract:OBJECTIVE:Prognosis of patients with head and neck squamous cell carcinoma (HNSCC) is still poor. Novel therapeutic approaches are of great interest to improve the effects of radiochemotherapy. We evaluated the effects of tyrosine kinase inhibitor neratinib on HNSCC cell lines CAL27, SCC25 and FaDu as a single agent an...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Schneider S,Thurnher D,Kadletz L,Seemann R,Brunner M,Kotowski U,Schmid R,Lill C,Heiduschka G

    更新日期:2016-11-01 00:00:00

  • Hydrolytic and depolymerising enzyme activity of Prevotella intermedia and Prevotella nigrescens.

    abstract:OBJECTIVE:Prevotella intermedia has been reported to be associated with periodontal disease whilst P. nigrescens has predominantly been isolated from more specific conditions and healthy sites. The aim of the present study was to compare the enzyme activity of these species. MATERIALS AND METHODS:Nine strains of P. in...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Stubbs S,Lewis MA,Waddington RJ,Embery G

    更新日期:1996-12-01 00:00:00

  • Pigmented lesions of the oral mucosa: A cross-sectional study of 458 histopathological specimens.

    abstract:OBJECTIVES:To evaluate clinical, demographic, and histopathological characteristics of pigmented lesions of the oral mucosa. MATERIALS AND METHODS:A cross-sectional study was conducted over a 64-year period. Information was collected from medical charts, and all archived histopathological specimens with diagnoses of a...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Tavares TS,Meirelles DP,de Aguiar MCF,Caldeira PC

    更新日期:2018-11-01 00:00:00

  • Increased expression of TRPV1 in squamous cell carcinoma of the human tongue.

    abstract:OBJECTIVES:Recent reports have unambiguously identified the presence and the growth-modulatory role of transient receptor potential vanilloid-1 (TRPV1), a central integrator of pain sensation, on numerous non-neuronal cell types and, of great importance, in certain malignancies. In this study, we have investigated the ...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Marincsák R,Tóth BI,Czifra G,Márton I,Rédl P,Tar I,Tóth L,Kovács L,Bíró T

    更新日期:2009-07-01 00:00:00

  • Functional variants of IL4 and IL6 genes and risk of tobacco-related oral carcinoma in high-risk Asian Indians.

    abstract:BACKGROUND:Tobacco-related oral squamous cell carcinoma (OSCC) is one of the most common cancers involving Indian males. We assessed the association of IL4 promoter -589 T>C, -33 T>C, and IL6-174 G>C functional genetic polymorphisms with tobacco-related OSCC in Asian Indians. PATIENTS AND METHODS:The IL4 and IL6 promo...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Gaur P,Mittal M,Mohanti B,Das S

    更新日期:2011-10-01 00:00:00

  • Tumour necrosis factor-alpha gene polymorphisms and susceptibility to oral lichen planus.

    abstract:OBJECTIVE: This study is aimed to investigate the association between OLP susceptibility and clinical type in the Thai population and three polymorphisms within the promoter region of the TNF-α at positions -863, -308 and -238 which have putative functional significances. MATERIALS AND METHODS: Genomic DNA from 75 Tha...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Kimkong I,Hirankarn N,Nakkuntod J,Kitkumthorn N

    更新日期:2011-03-01 00:00:00

  • Local drug delivery for oral mucosal diseases: challenges and opportunities.

    abstract::There are few topical formulations used for oral medicine applications most of which have been developed for the management of dermatological conditions. As such, numerous obstacles are faced when utilizing these preparations in the oral cavity, namely enzymatic degradation, taste, limited surface area, poor tissue pe...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审


    authors: Sankar V,Hearnden V,Hull K,Juras DV,Greenberg MS,Kerr AR,Lockhart PB,Patton LL,Porter S,Thornhill M

    更新日期:2011-04-01 00:00:00

  • Arecoline-stimulated placenta growth factor production in gingival epithelial cells: modulation by curcumin.

    abstract:OBJECTIVE:Placenta growth factor (PlGF) is associated with the progression and prognosis of oral cancer. MATERIALS AND METHODS:This study used ELISA, quantitative polymerase chain reaction, and Western blotting to study the arecoline-stimulated (PlGF) protein or mRNA expression in human gingival epithelial S-G cells. ...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Cheng SJ,Ko HH,Cheng SL,Lee JJ,Chen HM,Chang HH,Kok SH,Kuo MY,Chiang CP

    更新日期:2013-07-01 00:00:00

  • The association between serum 25-hydroxyvitamin D levels and dental caries in US adults.

    abstract:OBJECTIVES:We investigated whether 25-hydroxyvitamin D concentration is independently associated with dental caries among adults in the United States. SUBJECTS AND METHODS:This investigation was a cross-sectional study. A total of 4,244 participants (aged 20-80 years) were enrolled through the 2007-2008 National Healt...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Zhou F,Zhou Y,Shi J

    更新日期:2020-10-01 00:00:00

  • Bacteremia after supragingival scaling and dental extraction: Culture and molecular analyses.

    abstract:OBJECTIVE:To study the incidence and magnitude of bacteremia after dental extraction and supragingival scaling. SUBJECTS AND METHODS:Blood samples were taken before and 5 and 30 min after dental extraction and supragingival scaling from individuals at high (n = 44) or negligible risk (n = 51) for infective endocarditi...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Reis LC,Rôças IN,Siqueira JF Jr,de Uzeda M,Lacerda VS,Domingues R,Miranda KR,Saraiva RM

    更新日期:2018-05-01 00:00:00

  • Pathogenesis investigation of miR-199-5p in oral submucous fibrosis based on bioinformatics analysis.

    abstract:OBJECTIVES:Fibrosis diseases are one of the leading causes of suffering and death. However, no systematic investigation has been carried out on fibrosis-related genes. MATERIALS AND METHODS:By querying PubMed using keywords "fibrosis" and "gene" or "protein," we identified fibrosis-related genes in the last decade. Bi...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Yuan Y,Li N,Zeng L,Shen Z,Jiang C

    更新日期:2019-03-01 00:00:00

  • Herpesviruses viral loads and levels of proinflammatory cytokines in apical periodontitis.

    abstract:OBJECTIVES:This study aimed to analyse Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) viral loads in symptomatic and asymptomatic apical periodontitis lesions, to determine levels of TNF-α, IL-1β and IL-6 in these lesions and to investigate a possible correlation between herpesviral copy numbers and levels o...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Jakovljevic A,Knezevic A,Nikolic N,Soldatovic I,Jovanovic T,Milasin J,Andric M

    更新日期:2018-07-01 00:00:00

  • Surface properties of lactobacilli isolated from healthy subjects.

    abstract:OBJECTIVE:Lactobacilli are considered cariogenic micro-organisms. As oral species of lactobacilli have not been thoroughly described, the aim of this work was to isolated and identify these organisms from teeth, tongue, saliva and gum of healthy patients and to describe some of their surface properties. SUBJECTS:Forty...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Colloca ME,Ahumada MC,López ME,Nader-Macías ME

    更新日期:2000-07-01 00:00:00

  • CD10 expression in stromal cells of oral cavity squamous cell carcinoma: a clinic and pathologic correlation.

    abstract:OBJECTIVE:CD10 is expressed on the majority of follicle-center lymphomas and Burkitt lymphomas. CD10 has also been shown to be present in a variety of other neoplasms. DESIGN:The aim of this study was a correlation of CD10 and several parameters: age, tumor size, presence of lymph node metastases, clinic stage, histol...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Piattelli A,Fioroni M,Iezzi G,Perrotti V,Stellini E,Piattelli M,Rubini C

    更新日期:2006-05-01 00:00:00

  • Periodontitis and respiratory diseases: A systematic review with meta-analysis.

    abstract:OBJECTIVE:To conduct a systematic review and meta-analysis to evaluate the recent scientific literature addressing the association between periodontitis and asthma, chronic obstructive pulmonary disease (COPD), and pneumonia. MATERIALS AND METHODS:The search for studies was carried out using MEDLINE/PubMed, EMBASE, Li...

    journal_title:Oral diseases

    pub_type: 杂志文章,meta分析


    authors: Gomes-Filho IS,Cruz SSD,Trindade SC,Passos-Soares JS,Carvalho-Filho PC,Figueiredo ACMG,Lyrio AO,Hintz AM,Pereira MG,Scannapieco F

    更新日期:2020-03-01 00:00:00

  • Andrographolide-loaded solid lipid nanoparticles enhance anti-cancer activity against head and neck cancer and precancerous cells.

    abstract:BACKGROUND:Increasing evidence indicates that andrographolide (ADG) exhibits anti-cancer activity against various cancer cell lines. However, its high hydrophobicity and poor bioavailability restrict its clinical application as a chemopreventative agent. Previously, we have shown that ADG-loaded solid lipid nanoparticl...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Li H,Qu X,Qian W,Song Y,Wang C,Liu W

    更新日期:2020-12-09 00:00:00

  • Toward gene therapy for growth hormone deficiency via salivary gland expression of growth hormone.

    abstract:OBJECTIVES:Salivary glands are useful targets for gene therapeutics. After gene transfer into salivary glands, regulated secretory pathway proteins, such as human growth hormone, are secreted into saliva, whereas constitutive secretory pathway proteins, such as erythropoietin, are secreted into the bloodstream. Secreti...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Racz GZ,Zheng C,Goldsmith CM,Baum BJ,Cawley NX

    更新日期:2015-03-01 00:00:00

  • Hyaline ring granuloma of the mouth-A foreign-body reaction that dentists should be aware of: Critical review of literature and histochemical/immunohistochemical study of a new case.

    abstract::Hyaline ring granuloma (HRG) is a rare and atypical foreign-body granulomatous chronic inflammatory condition. Our aim was to make a critical review of the literature cases and also to illustrate histochemical and immunohistochemical findings of a new case. A modified PICO strategy was used. Inclusion criteria were me...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审


    authors: Kimura TC,Carneiro MC,Coelho YFS,de Sousa SCOM,Veltrini VC

    更新日期:2020-01-24 00:00:00

  • Prevalence of hepatitis virus infection in association with oral diseases requiring surgery.

    abstract:OBJECTIVE:We evaluated the prevalence of hepatitis virus infection in a large population of patients in terms of diseases requiring oral surgery. DESIGN:Retrospective case survey. SUBJECTS AND METHODS:Prevalence of hepatitis B and C virus (HBV, HCV) infection were compared between oral diseases such as inflammation, ...

    journal_title:Oral diseases

    pub_type: 杂志文章


    authors: Takata Y,Takahashi T,Fukuda J

    更新日期:2002-03-01 00:00:00

  • An update of knowledge on the regulatory role of Treg cells in apical periodontitis.

    abstract::Apical periodontitis (AP) is a prevalent infectious and inflammatory disorder that involves inflammation of periapical tissues and the disintegration of alveolar bone. AP may eventually lead to tooth loss if not timely treated. This disease is caused by pathogenic bacteria in the necrotic pulps and root canals, thereb...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审


    authors: Wei L,Xu M,Xiong H

    更新日期:2020-06-02 00:00:00