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The advantage of digital tomosynthesis for pulmonary nodule detection concerning influence of nodule location and size: a phantom study.

Abstract：

AIM:To investigate the advantage of digital tomosynthesis (DTS) over chest radiography (CXR) and dual-energy subtraction radiography (DES) for pulmonary nodule detection according to the location and size of solid simulated pulmonary nodules (SPNs). MATERIALS AND METHODS:Ninety-six SPNs of variable sizes were inserted into eight different regions of a lung phantom. These regions were further classified into two groups of danger and non-danger zones based on anatomical location influencing the detection of pulmonary nodules. The 96 cases with inserted SPNs and an additional nodule-free 96 control cases all underwent CXR, DES, and DTS examinations. Three observers independently reviewed all the images. The jackknife alternative free-response receiver operating characteristic was used to analyse diagnostic performance for each technique. RESULTS:DTS was superior to CXR and DES for detection of smaller SPNs, except in the retrodiaphragmatic and apical regions. DTS outperformed CXR and DES for detection of larger SPNs in the paramediastinal region. For 5- and 8-mm SPNs, DTS was superior to CXR and DES in the apical, paramediastinal and lateral pulmonary regions. In the retrodiaphragmatic region, the three techniques showed similar diagnostic performance regardless of the SPN size. DES was similar to DTS for detection of 8-mm SPN in the apical region. For 10- and 12-mm SPNs, CXR and DES showed similar diagnostic performance to DTS in the apical and lateral pulmonary regions; however, DTS was superior to CXR and DES in the paramediastinal region. CONCLUSIONS:DTS significantly improved the capability to detect synthetic pulmonary nodules compared with CXR and DES, for detection of smaller nodules in the apical, paramediastinal, and lateral pulmonary regions, and larger nodules located in the paramediastinal region in a thoracic phantom.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

Kim EY,Bista AB,Kim T,Park SY,Park KJ,Kang DK,Sun JS

doi

10.1016/j.crad.2017.03.022

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

796.e1-796.e8

issue

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(17)30131-9

journal_volume

pub_type

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The advantage of digital tomosynthesis for pulmonary nodule detection concerning influence of nodule location and size: a phantom study.