Abstract:
:The present study describes the case of a 63-year-old woman presenting with headache, dizziness and vomiting due to a an ovoid mass in the left pre-bulbar cistern, apparently arising from the lower clivus and the foramen magnum. The clinical history revealed the subtotal removal of a right cerebellar low-grade glioma 15 years previously and subsequent conventional 60-Gy radiotherapy. Notably, following gross total resection, histopathological examination showed microscopic features that resulted in a diagnosis of anaplastic ependymoma. The patient underwent surgery to remove the mass and post-operative chemotherapy with temozolomide. A progressive improvement of neurological signs and symptoms was observed during the postoperative course. At the 6-month follow-up, the patient was free from clinical and radiological recurrence. The unusual features of this rare secondary brain tumor were the extrassial location in the posterior fossa, the unusual age-associated location of the histological subtype and the fact that it closely mimicked a skull-base meningioma.
journal_name
Exp Ther Medjournal_title
Experimental and therapeutic medicineauthors
Spallone A,Marchione P,DI Capua M,Belvisi Ddoi
10.3892/etm.2015.2945subject
Has Abstractpub_date
2016-02-01 00:00:00pages
455-457issue
2eissn
1792-0981issn
1792-1015pii
ETM-0-0-2945journal_volume
11pub_type
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