Abstract:
OBJECTIVES:To assess the incidence of chronic illness and its effect on veteran centenarians. DESIGN:Retrospective longitudinal cohort study. SETTING:United States Veterans Affairs Corporate Data Warehouse (CDW). PARTICIPANTS:Community-dwelling veterans born between 1910 and 1915 who survived to at least age 80 (N = 86,892; 31,121 octogenarians, 52,420 nonagenarians, 3,351 centenarians). MEASUREMENTS:The Kaplan-Meier method was used to estimate cumulative incidence of chronic conditions according to age group. Incidence rates were compared using the log-rank test. Cox proportional hazards models were used to estimate unadjusted hazard ratios. RESULTS:Ninety-seven percent of Centenarians were male, 88.0% were white, 31.8% were widowed, 87.5% served in World War II, and 63.9% did not have a service-related disability. The incidence rates of chronic illnesses were higher in octogenarians than centenarians (atrial fibrillation, 15.0% vs 0.6%, P < .001; heart failure, 19.3% vs 0.4%, P < .001; chronic obstructive pulmonary disease, 17.9% vs 0.6%, P < .001; hypertension, 29.6% vs 3.0%, P < .001; end-stage renal disease, 7.2% vs 0.1%, P < .001; malignancy, 14.1% vs 0.6%, P < .001; diabetes mellitus, 11.1% vs 0.4%, P < .001; stroke, 4.6% vs 0.4%, P < .001) and in nonagenarians than centenarians (atrial fibrillation, 13.2% vs 3.5%, P < .001; heart failure, 15.8% vs 3.3%, P < .001; chronic obstructive pulmonary disease, 11.8% vs 3.5%, P < .001; hypertension, 27.2% vs 12.8%, P < .001; end-stage renal disease, 11.9% vs 4.5%, P < .001; malignancy, 8.6% vs 2.3%, P < .001; diabetes mellitus, 7.5% vs 2.2%, P < .001; and stroke, 3.5% vs 1.3%, P < .001). CONCLUSION:In a large cohort of predominantly male community-dwelling elderly veterans, centenarians had a lower incidence of chronic illness than those in their 80s and 90s, demonstrating similar compression of morbidity and extension of health span observed in other studies.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Kheirbek RE,Fokar A,Shara N,Bell-Wilson LK,Moore HJ,Olsen E,Blackman MR,Llorente MDdoi
10.1111/jgs.14900subject
Has Abstractpub_date
2017-09-01 00:00:00pages
2100-2106issue
9eissn
0002-8614issn
1532-5415journal_volume
65pub_type
杂志文章abstract::Thyroid disease in the aged, both hypothyroidism and hyperthyroidism, may be subtle or may be present with no clinical symptoms and signs, and is therefore difficult to diagnose on the basis of clinical evaluation. The help of the laboratory is essential in making the diagnosis of disease of the thyroid. Therapeutic s...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.1993.tb06488.x
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVES:To explore how different frameworks and categories of chronic conditions impact multimorbidity (defined as two or more chronic conditions) prevalence estimates and associations with patient-important functional outcomes. DESIGN:Baseline data from a population-based cohort study. SETTING:National sample of ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15921
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To determine the usefulness of timed manual performance measurements (TMP) as predictors of health outcomes, hospitalization, and mortality in a large, heterogeneous sample of elderly people living in the community. DESIGN:Prospective cohort study. SETTING:Central North Carolina. PARTICIPANTS:1,286 communi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1994.tb06068.x
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:To obtain population-based estimates of emergency department (ED) visits by long-term care (LTC) residents. DESIGN:Retrospective cohort study using administrative data. SETTING:All LTC facilities in Ontario, Canada. PARTICIPANTS:All LTC residents who visited an ED at least once during a 6-month period. M...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2010.02736.x
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:To examine whether arterial stiffness is a risk factor for falls in community-dwelling older people. DESIGN:Prospective cohort study. SETTING:Community population, Sydney, Australia. PARTICIPANTS:Community-dwelling older adults (mean age 79.8±4.4, 52.2% female; N=481). MEASUREMENTS:Carotid-femoral pulse ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12931
更新日期:2014-08-01 00:00:00
abstract::It has long been thought that demographic aging and its attendant implications for health and social services is primarily a problem for industrialized wealthy countries. Nothing could be further from the truth since most older persons (and an increasingly higher number) reside in low-income countries. Through a descr...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.16191
更新日期:2019-11-01 00:00:00
abstract::In this study an attempt was made to determine the relationship between cerebral amyloid angiopathy (AA) and other cerebrovascular lesions in the aged. The brains of 128 autopsy patients over 60 years of age were examined by both light and electron microscopy. The frequency of cerebral AA increased with age and was 58...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1981.tb01757.x
更新日期:1981-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To assess the course and prediction of basic activities of daily living (ADL) function in patients after transcatheter aortic valve implantation (TAVI). DESIGN:This was a prospective cohort study. SETTING:The setting was a single academic center in Switzerland. PARTICIPANTS:Participants include...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16927
更新日期:2020-11-06 00:00:00
abstract:OBJECTIVES:To describe the natural history of frailty transitions in a large cohort of community-dwelling older men and identify predictors associated with progression to or improvement from states of greater frailty. DESIGN:Prospective cohort study. SETTING:Six U.S. sites. PARTICIPANTS:Community-dwelling men aged 6...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15003
更新日期:2017-11-01 00:00:00
abstract::It has been reported that postural hypotension in the elderly is common. However, these studies included institutionalized and more or less disabled persons. Furthermore, postural hypotension may be related to baseline blood pressure. In this study, the influence of age and blood pressure on the hemodynamic and plasma...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1989.tb05684.x
更新日期:1989-06-01 00:00:00
abstract:OBJECTIVES:To examine the relationship between persistently high depressive symptoms and long-term changes in functional disability in elderly persons. DESIGN:A community-based, prospective, observational study. SETTING:Participant data from the Cardiovascular Health Study. PARTICIPANTS:From the overall sample of 5,...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53202.x
更新日期:2005-04-01 00:00:00
abstract::Research indicates that lower extremity muscle weakness in the elderly is consistently related to impaired mobility and fall risk. Reversible components of the muscle weakness of aging include underuse syndromes and undernutrition, both of which are prevalent in nursing home populations. The Boston FICSIT study is a n...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1993.tb06714.x
更新日期:1993-03-01 00:00:00
abstract:OBJECTIVES:To identify risk factors for new-onset geriatric epilepsy that may trigger clinicians to consider a differential diagnosis of epilepsy at symptom onset. DESIGN:Retrospective cohort study. SETTING:National Veterans Affairs (VA) databases. PARTICIPANTS:Veterans aged 66 and older in fiscal year 2000 (FY00) w...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.02124.x
更新日期:2009-02-01 00:00:00
abstract::The reported prevalence of depressive symptomatology among the elderly ranges from 5 to 65 percent in hospital and community populations. Depression is considered the most common emotional disorder of advanced age. One of the chief diagnostic problems has been the lack of differentiation between disorders manifested b...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1980.tb00205.x
更新日期:1980-02-01 00:00:00
abstract::Close to 6 million Americans have Alzheimer's disease (AD) or Alzheimer's disease and related dementia (AD/ADRD). These high-need, high-cost patients are vulnerable to receiving poor quality uncoordinated care, ultimately leading to adverse health outcomes, poor quality of life, and misuse of resources. Improving the ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16621
更新日期:2020-07-01 00:00:00
abstract::The incidence, ecology, and mortality of gram-negative bacillary bacteremia in elderly patients were studied in an analysis of 334 episodes over a four-year-period in a 489-bed North Carolina community teaching hospital, 135 (40.4%) of which occurred in patients 70 years of age or older. The bacteremia rate per 1000 h...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1987.tb02311.x
更新日期:1987-03-01 00:00:00
abstract:CONTEXT:Racial differences in receipt of cancer prevention services may be related to poorer outcomes for minorities. Understanding reasons for such differences could help target appropriate interventions. OBJECTIVES:To determine if racial differences exist in the use of cancer prevention services among older blacks a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb04746.x
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:To compare the trajectories of motor and cognitive decline in older adults who progress to dementia with the trajectories of those who do not. To evaluate the added value of measuring motor and cognitive decline longitudinally versus cross-sectionally for predicting dementia. DESIGN:Prospective cohort study...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15341
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVES:To determine the extent to which disease-related symptoms and impairments, which constitute measures of disease severity or targets of therapy, account for the associations between chronic diseases and universal health outcomes. DESIGN:Cross-sectional. SETTING:The Cardiovascular Health Study (CHS) and the ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03576.x
更新日期:2011-09-01 00:00:00
abstract::The effects of Gerovital H3 (a specially stabilized form of procaine hydrochloride) on geriatric psychiatric patients were assessed in a double-blind study at Bronx State Hospital. The mean age of the subjects was 73 years and the average rating for the severity of organic symptoms was "moderate." During the first six...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章
doi:10.1111/j.1532-5415.1975.tb00326.x
更新日期:1975-08-01 00:00:00
abstract:OBJECTIVE:To assess the validity of several equations for estimating creatinine clearance in a large sample of high-functioning, community-dwelling elderly. DESIGN:Serum and 12-hour urine samples were collected and assayed for creatinine using the Jaffe total chromagen method. Fifteen clearance-estimating equations we...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1993.tb07459.x
更新日期:1993-07-01 00:00:00
abstract:OBJECTIVES:To test whether Stepping On, a multifaceted community-based program using a small-group learning environment, is effective in reducing falls in at-risk people living at home. DESIGN:A randomized trial with subjects followed for 14 months. SETTING:The interventions were conducted in community venues, with a...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2004.52411.x
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:The impact of cognitive function and decline on political ideology is unknown. We studied the relationship between cognition and both political orientation and political policy choices in a population of older persons. DESIGN:Longitudinal investigation. SETTING:A retirement community and its surroundings in...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16935
更新日期:2020-10-31 00:00:00
abstract:OBJECTIVES:To examine current utilization patterns of cholinesterase inhibitor (ChEI) therapy for dementia to determine treatment duration, use in long-term care, how often patients receive these drugs until death, and frequency of switching between the available ChEIs. DESIGN:A population-based healthcare administrat...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2007.01377.x
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:To determine whether metabolic syndrome is an independent predictor of decline in mobility in an elderly community sample. DESIGN:Biracial community-based prospective cohort study. SETTING:Urban and rural areas of central North Carolina. PARTICIPANTS:One thousand two hundred twenty-nine older African Amer...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.00607.x
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVES:To identify factors associated with incomplete bladder emptying in older women with overactive bladder (OAB) symptoms. DESIGN:Retrospective medical records review. SETTING:Urodynamic laboratory at a large academic health care system in the southeast United States. PARTICIPANTS:Medical records from women a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13474
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:To provide estimates of change in depressive symptoms and determine how changes in depressive symptom influence recovery of functional status. DESIGN:Prospective cohort study. SETTING:Eleven inpatient medical rehabilitation facilities located across the United States. PARTICIPANTS:Five hundred forty-four ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2010.03266.x
更新日期:2011-02-01 00:00:00
abstract::Contrary to earlier findings, elderly patients are not at significantly greater risk of perioperative morbidity or mortality than younger patients simply because of advanced age. Increased risk, when present, is attributable to pathologic changes that are not uniformly seen in all geriatric patients. Most perioperativ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1983.tb04606.x
更新日期:1983-10-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation on quality of life (QOL). DESIGN:Randomized, double-blind, placebo-controlled trial. SETTING:Independently living individuals from the general older Dutch population. PARTICIPANTS:Three hundred two ind...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2009.02361.x
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVES:To describe decade- long trends (1999-2009) in the rates of not undergoing cardiac catheterization and percutaneous coronary intervention (PCI) in individuals aged 65 and older presenting with an ST-segment elevation acute myocardial infarction (STEMI) and factors associated with not undergoing these procedu...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.13399
更新日期:2015-05-01 00:00:00